Symptoms and duration of the prodromal phase in parkinson's disease
Identifieur interne : 002965 ( Istex/Corpus ); précédent : 002964; suivant : 002966Symptoms and duration of the prodromal phase in parkinson's disease
Auteurs : Ed G. Gonera ; Martin Van'T Hof ; Hans J. C. Berger ; Chris Van Weel ; HorstinkSource :
- Movement Disorders [ 0885-3185 ] ; 1997-11.
English descriptors
Abstract
To investigate the duration of a prodromal phase before the onset of the classic symptoms of idiopathic Parkinson's disease the authors conducted a retrospective case control study of 60 patients with Parkinson's disease and 58 age‐ and sex‐matched control subjects, covering the decade preceding the onset of classic Parkinson's disease. The symptoms were derived from files of the patients general practitioners. Compared with control subjects, patients pre‐Parkinson's disease had more central nervous system, psychologic, musculoskeletal, and cardiovascular (i.e., autonomic) symptoms. Patients pre‐Parkinson's disease also made more visits to general practitioners and medical specialists. The results indicate that the onset of classic parkinsonism is frequently precede by a prodromal phase lasting from 4–6 years.
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DOI: 10.1002/mds.870120607
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ISTEX:272AF50BC9F94B8233CBFC32F1D7A88ABF43F63FLe document en format XML
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The symptoms were derived from files of the patients general practitioners. Compared with control subjects, patients pre‐Parkinson's disease had more central nervous system, psychologic, musculoskeletal, and cardiovascular (i.e., autonomic) symptoms. Patients pre‐Parkinson's disease also made more visits to general practitioners and medical specialists. 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The symptoms were derived from files of the patients general practitioners. Compared with control subjects, patients pre‐Parkinson's disease had more central nervous system, psychologic, musculoskeletal, and cardiovascular (i.e., autonomic) symptoms. Patients pre‐Parkinson's disease also made more visits to general practitioners and medical specialists. The results indicate that the onset of classic parkinsonism is frequently precede by a prodromal phase lasting from 4–6 years.</abstract><subject lang="en"><genre>Keywords</genre><topic>Prodromal symptom</topic><topic>Preclinical phase</topic><topic>Parkinson's disease</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. 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