Effect of treatment with intravenous immunoglobulin on quality of life in patients with stiff‐person syndrome
Identifieur interne : 004483 ( Main/Exploration ); précédent : 004482; suivant : 004484Effect of treatment with intravenous immunoglobulin on quality of life in patients with stiff‐person syndrome
Auteurs : Willibald Gerschlager [Royaume-Uni] ; Peter Brown [Royaume-Uni]Source :
- Movement Disorders [ 0885-3185 ] ; 2002-05.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Adulte.
English descriptors
- KwdEn :
- Adult, Aged, Case study, Chemotherapy, Evolution, Female, Humans, Immunoglobulins, Immunoglobulins, Intravenous (therapeutic use), Intravenous administration, Male, Middle Aged, Prognosis, Quality of Life, Quality of life, Questionnaires, Stiff man syndrome, Stiff-Person Syndrome (drug therapy), Stiff-Person Syndrome (psychology), Time Factors, Treatment, Treatment Outcome, quality of life, stiff‐person syndrome.
- MESH :
- chemical , therapeutic use : Immunoglobulins, Intravenous.
- drug therapy : Stiff-Person Syndrome.
- psychology : Stiff-Person Syndrome.
- Aged, Female, Humans, Male, Middle Aged, Quality of Life, Questionnaires, Time Factors, Treatment Outcome.
Abstract
The therapeutic effects of intravenous immunoglobulin (IVIG) on the stiff‐person syndrome (SPS) have been described exclusively in case reports or open‐label studies in terms of clinical outcomes. We investigate whether IVIG improves quality of life (QoL) in the SPS. Six patients with the classic form of SPS completed a generic QoL instrument, the SF‐36, and a Visual Analogue Scale (VAS) before treatment as well as 2 weeks after completion of a course of IVIG. There was significant improvement in the SF‐36 subscores for pain, social functioning, general mental health, and energy–vitality with treatment. The VAS also improved significantly. We conclude that treatment with IVIG improves QoL in the SPS. © 2002 Movement Disorder Society.
Url:
DOI: 10.1002/mds.10043
Affiliations:
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Le document en format XML
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We investigate whether IVIG improves quality of life (QoL) in the SPS. Six patients with the classic form of SPS completed a generic QoL instrument, the SF‐36, and a Visual Analogue Scale (VAS) before treatment as well as 2 weeks after completion of a course of IVIG. There was significant improvement in the SF‐36 subscores for pain, social functioning, general mental health, and energy–vitality with treatment. The VAS also improved significantly. We conclude that treatment with IVIG improves QoL in the SPS. © 2002 Movement Disorder Society.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li></region><settlement><li>Londres</li></settlement></list><tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Gerschlager, Willibald" sort="Gerschlager, Willibald" uniqKey="Gerschlager W" first="Willibald" last="Gerschlager">Willibald Gerschlager</name></region><name sortKey="Brown, Peter" sort="Brown, Peter" uniqKey="Brown P" first="Peter" last="Brown">Peter Brown</name><name sortKey="Brown, Peter" sort="Brown, Peter" uniqKey="Brown P" first="Peter" last="Brown">Peter Brown</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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