Validity of the 30‐item geriatric depression scale in patients with Parkinson's disease
Identifieur interne : 003126 ( Main/Exploration ); précédent : 003125; suivant : 003127Validity of the 30‐item geriatric depression scale in patients with Parkinson's disease
Auteurs : William M. Mcdonald [États-Unis] ; Paul E. Holtzheimer [États-Unis] ; Michael Haber [États-Unis] ; Jerrold L. Vitek [États-Unis] ; Kimberly Mcwhorter [États-Unis] ; Mahlon Delong [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2006-10.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Aged, Depression, Depressive Disorder, Major (diagnosis), Depressive Disorder, Major (psychology), Female, Geriatric Assessment (statistics & numerical data), Geriatrics, Human, Humans, Male, Middle Aged, Mood disorder, Nervous system diseases, Pallidotomy, Parkinson Disease (psychology), Parkinson Disease (surgery), Parkinson disease, Parkinson's disease, Personality Inventory (statistics & numerical data), Postoperative Complications (diagnosis), Postoperative Complications (psychology), Psychometrics (statistics & numerical data), ROC Curve, Reproducibility of Results, Validity, depressive disorders, mood disorders due to general medical conditions, rating scales.
- MESH :
- diagnosis : Depressive Disorder, Major, Postoperative Complications.
- psychology : Depressive Disorder, Major, Parkinson Disease, Postoperative Complications.
- statistics & numerical data : Geriatric Assessment, Personality Inventory, Psychometrics.
- surgery : Parkinson Disease.
- Aged, Female, Humans, Male, Middle Aged, Pallidotomy, ROC Curve, Reproducibility of Results.
Abstract
Depression in Parkinson's disease (dPD) is difficult to diagnose because depressive symptoms can overlap with symptoms of Parkinson's disease (PD). Subject‐rated scales such as the 30‐item Geriatric Depression Scale (GDS) may be useful in screening for dPD. There were 57 patients (33 men, 24 women; mean age, 58.6 years [SD ± 8.4]) enrolled in a study of pallidotomy for intractable PD who were evaluated for depression before and after surgery. Subjects were evaluated using the 17‐item Hamilton Depression Rating Scale (HDRS), Structured Clinical Interview for Diagnostic and Statistical Manual‐III (SCID), and the GDS. SCID was used to diagnose major depression with confirmation by an expert geropsychiatrist. Receiver‐operating curves (ROC) were used to identify cutoff points with maximal discriminant validity for diagnosing dPD. A total of 213 evaluation time points were included for the 52 patients with time points that included a valid SCID diagnosis, GDS, and HDRS. A ROC established points of maximum specificity/sensitivity for the GDS at a cutoff of 9/10 (sensitivity = 0.809, specificity = 0.837, positive predictive value [PPV] = 0.584, negative predictive value [NPV] = 0.939) and for the HDRS at a cutoff of 12/13 (sensitivity = 0.810, specificity = 0.821, PPV = 0.580, NPV = 0.934). The GDS was moderately correlated with the HDRS (Pearson's r = 0.54; P < 0.001). The GDS is useful in screening for dPD. A cutoff score of 9/10 has acceptable discriminant validity for dPD, and the GDS has a moderate correlation with the HDRS in PD patients. © 2005 Movement Disorder Society
Url:
DOI: 10.1002/mds.21023
Affiliations:
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Le document en format XML
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<term>Depression</term>
<term>Depressive Disorder, Major (diagnosis)</term>
<term>Depressive Disorder, Major (psychology)</term>
<term>Female</term>
<term>Geriatric Assessment (statistics & numerical data)</term>
<term>Geriatrics</term>
<term>Human</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Mood disorder</term>
<term>Nervous system diseases</term>
<term>Pallidotomy</term>
<term>Parkinson Disease (psychology)</term>
<term>Parkinson Disease (surgery)</term>
<term>Parkinson disease</term>
<term>Parkinson's disease</term>
<term>Personality Inventory (statistics & numerical data)</term>
<term>Postoperative Complications (diagnosis)</term>
<term>Postoperative Complications (psychology)</term>
<term>Psychometrics (statistics & numerical data)</term>
<term>ROC Curve</term>
<term>Reproducibility of Results</term>
<term>Validity</term>
<term>depressive disorders</term>
<term>mood disorders due to general medical conditions</term>
<term>rating scales</term>
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<term>Parkinson Disease</term>
<term>Postoperative Complications</term>
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<term>Personality Inventory</term>
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<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Pallidotomy</term>
<term>ROC Curve</term>
<term>Reproducibility of Results</term>
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<term>Homme</term>
<term>Parkinson maladie</term>
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<term>Validité</term>
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<front><div type="abstract" xml:lang="en">Depression in Parkinson's disease (dPD) is difficult to diagnose because depressive symptoms can overlap with symptoms of Parkinson's disease (PD). Subject‐rated scales such as the 30‐item Geriatric Depression Scale (GDS) may be useful in screening for dPD. There were 57 patients (33 men, 24 women; mean age, 58.6 years [SD ± 8.4]) enrolled in a study of pallidotomy for intractable PD who were evaluated for depression before and after surgery. Subjects were evaluated using the 17‐item Hamilton Depression Rating Scale (HDRS), Structured Clinical Interview for Diagnostic and Statistical Manual‐III (SCID), and the GDS. SCID was used to diagnose major depression with confirmation by an expert geropsychiatrist. Receiver‐operating curves (ROC) were used to identify cutoff points with maximal discriminant validity for diagnosing dPD. A total of 213 evaluation time points were included for the 52 patients with time points that included a valid SCID diagnosis, GDS, and HDRS. A ROC established points of maximum specificity/sensitivity for the GDS at a cutoff of 9/10 (sensitivity = 0.809, specificity = 0.837, positive predictive value [PPV] = 0.584, negative predictive value [NPV] = 0.939) and for the HDRS at a cutoff of 12/13 (sensitivity = 0.810, specificity = 0.821, PPV = 0.580, NPV = 0.934). The GDS was moderately correlated with the HDRS (Pearson's r = 0.54; P < 0.001). The GDS is useful in screening for dPD. A cutoff score of 9/10 has acceptable discriminant validity for dPD, and the GDS has a moderate correlation with the HDRS in PD patients. © 2005 Movement Disorder Society</div>
</front>
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<name sortKey="Holtzheimer, Paul E" sort="Holtzheimer, Paul E" uniqKey="Holtzheimer P" first="Paul E." last="Holtzheimer">Paul E. Holtzheimer</name>
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