Myoclonus in corticobasal degeneration
Identifieur interne : 005299 ( Main/Curation ); précédent : 005298; suivant : 005300Myoclonus in corticobasal degeneration
Auteurs : Carella [Italie] ; Claudia Ciano [Italie] ; Ferruccio Panzica [Italie] ; Vidmer Scaioli [Italie]Source :
- Movement Disorders [ 0885-3185 ] ; 1997-07.
English descriptors
- KwdEn :
- Aged, Arm, Basal Ganglia (physiopathology), Basal Ganglia Diseases (complications), Basal Ganglia Diseases (physiopathology), Brain Diseases (complications), Brain Diseases (physiopathology), Cerebral Cortex (physiopathology), Corticobasal degeneration, Evoked Potentials, Somatosensory, Female, Humans, Long‐loop responses, Male, Middle Aged, Motor Cortex (physiopathology), Muscle, Skeletal (physiopathology), Myoclonus, Myoclonus (etiology), Myoclonus (physiopathology), Nerve Degeneration, Neural Conduction, Neural Pathways (physiopathology), Parkinson Disease (etiology), Parkinson Disease (physiopathology), Reaction Time, Reflex, Abnormal (physiology), Somatosensory evoked potential.
- MESH :
- complications : Basal Ganglia Diseases, Brain Diseases.
- etiology : Myoclonus, Parkinson Disease.
- physiology : Reflex, Abnormal.
- physiopathology : Basal Ganglia, Basal Ganglia Diseases, Brain Diseases, Cerebral Cortex, Motor Cortex, Muscle, Skeletal, Myoclonus, Neural Pathways, Parkinson Disease.
- Aged, Arm, Evoked Potentials, Somatosensory, Female, Humans, Male, Middle Aged, Nerve Degeneration, Neural Conduction, Reaction Time.
Abstract
Five patients with unilateral myoclonus and a clinical diagnosis of corticobasal degeneration (CBD) were studied. All patients showed enhanced long‐loop responses in their myoclonic arms without enlarged somatosensory potentials. The cortical relay time of the long‐loop responses was studied in three patients, in two of whom it was <2 ms, even in the nonmyoclonic arm. Myoclonus in CBD is probably related to an enhanced long‐loop reflex whose pathway is unlikely to be the same as that in classic cortical reflex myoclonus.
Url:
DOI: 10.1002/mds.870120419
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<term>Basal Ganglia (physiopathology)</term>
<term>Basal Ganglia Diseases (complications)</term>
<term>Basal Ganglia Diseases (physiopathology)</term>
<term>Brain Diseases (complications)</term>
<term>Brain Diseases (physiopathology)</term>
<term>Cerebral Cortex (physiopathology)</term>
<term>Corticobasal degeneration</term>
<term>Evoked Potentials, Somatosensory</term>
<term>Female</term>
<term>Humans</term>
<term>Long‐loop responses</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Motor Cortex (physiopathology)</term>
<term>Muscle, Skeletal (physiopathology)</term>
<term>Myoclonus</term>
<term>Myoclonus (etiology)</term>
<term>Myoclonus (physiopathology)</term>
<term>Nerve Degeneration</term>
<term>Neural Conduction</term>
<term>Neural Pathways (physiopathology)</term>
<term>Parkinson Disease (etiology)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Reaction Time</term>
<term>Reflex, Abnormal (physiology)</term>
<term>Somatosensory evoked potential</term>
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<term>Brain Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Myoclonus</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Reflex, Abnormal</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Basal Ganglia</term>
<term>Basal Ganglia Diseases</term>
<term>Brain Diseases</term>
<term>Cerebral Cortex</term>
<term>Motor Cortex</term>
<term>Muscle, Skeletal</term>
<term>Myoclonus</term>
<term>Neural Pathways</term>
<term>Parkinson Disease</term>
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<term>Arm</term>
<term>Evoked Potentials, Somatosensory</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
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<front><div type="abstract" xml:lang="en">Five patients with unilateral myoclonus and a clinical diagnosis of corticobasal degeneration (CBD) were studied. All patients showed enhanced long‐loop responses in their myoclonic arms without enlarged somatosensory potentials. The cortical relay time of the long‐loop responses was studied in three patients, in two of whom it was <2 ms, even in the nonmyoclonic arm. Myoclonus in CBD is probably related to an enhanced long‐loop reflex whose pathway is unlikely to be the same as that in classic cortical reflex myoclonus.</div>
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