MovDisordV3, Main, Curation, bibRecord, 002060

Serial volumetric MRI in Parkinsonian disorders

Identifieur interne : 002060 ( Main/Curation ); précédent : 002059; suivant : 002061

Serial volumetric MRI in Parkinsonian disorders

Auteurs : Edward J. Wild [Royaume-Uni] ; Nick C. Fox [Royaume-Uni]

Source :

Movement Disorders [ 0885-3185 ] ; 2009.

RBID : ISTEX:8D31798F89627389ED9EE4A060C8AEC61BF31A56

Descripteurs français

Pascal (Inist)
- Atrophie multisystématisée, Démence à corps de Lewy, Imagerie RMN, Maladie de Parkinson, Pathologie du système nerveux.

English descriptors

KwdEn :
- Disease Progression, Humans, Lewy Body Disease (pathology), Lewy body dementia, Magnetic Resonance Imaging (methods), Multiple System Atrophy (pathology), Multiple system atrophy, Nervous system diseases, Nuclear magnetic resonance imaging, Parkinson Disease (diagnosis), Parkinson Disease (pathology), Parkinson disease, Supranuclear Palsy, Progressive (pathology), dementia with lewy bodies, magnetic resonance imaging, multiple system atrophy, parkinson's disease, progressive supranuclear palsy.
MESH :
- diagnosis : Parkinson Disease.
- methods : Magnetic Resonance Imaging.
- pathology : Lewy Body Disease, Multiple System Atrophy, Parkinson Disease, Supranuclear Palsy, Progressive.
- Disease Progression, Humans.

Abstract

Tracking progression in neurodegenerative diseases is hampered by the limitations of the clinical rating scales, which are seldom linear, suffer from floor and ceiling effects, lack the ability to distinguish symptomatic change from disease modification, and are limited by imperfect intra‐ and inter‐rater reliability. The promise of an era of neuroprotective therapies renders urgent the search for reliable measures of progression. Biomarkers have the potential to enhance several aspects of both therapeutic trials and clinical practice. MRI‐based measures of cerebral volume can provide a surrogate for neuronal loss and several techniques have been applied to elucidate disease processes, aid diagnosis, and enable monitoring of progression in a variety of Parkinsonian disorders, including Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, progressive supranuclear palsy and Huntington's disease. We review the approaches to, and findings revealed by, serial volumetric MRI in these disorders. © 2009 Movement Disorder Society

Url:

https://api.istex.fr/document/8D31798F89627389ED9EE4A060C8AEC61BF31A56/fulltext/pdf

DOI: 10.1002/mds.22500

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ISTEX:8D31798F89627389ED9EE4A060C8AEC61BF31A56

Le document en format XML

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	Movement Disorders (revue)
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Movement Disorders (revue)

Serial volumetric MRI in Parkinsonian disorders

Serial volumetric MRI in Parkinsonian disorders

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

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