Visual hallucinations as REM sleep behavior disorders in patients with Parkinson's disease
Identifieur interne : 000521 ( Istex/Corpus ); précédent : 000520; suivant : 000522Visual hallucinations as REM sleep behavior disorders in patients with Parkinson's disease
Auteurs : Takashi Nomura ; Yuichi Inoue ; Hidetaka Mitani ; Ryuzo Kawahara ; Masahiro Miyake ; Kenji NakashimaSource :
- Movement Disorders [ 0885-3185 ] ; 2003-07.
English descriptors
Abstract
To clarify whether visual hallucinations in patients with Parkinson's disease (PD) are related to rapid eye movement (REM) sleep, nocturnal polysomnographic variables were compared between a group with hallucinations (hallucinators, n = 14) and a group without hallucinations (nonhallucinators, n = 8). A multiple sleep latency test (MSLT) was performed on 3 hallucinators, and the content of dreams during daytime REM sleep was investigated. The efficacy of clonazepam, a standard treatment choice for REM sleep behavior disorders, was investigated in 8 hallucinators. Nocturnal polysomnograms of the hallucinators showed a higher amount of stage 1–REM sleep with tonic electromyogram (stage 1–REM) than the nonhallucinators, and the reported occurrences of nocturnal hallucinations corresponded with the periods of stage REM or stage 1–REM in most hallucinators. The frequency of sleep onset REM periods (SOREMP) on the MSLT were pathologically high in the hallucinators, and the content of the dreams during the MSLT period was quite similar to their hallucinations. During clonazepam treatment, the frequency of hallucinatory symptoms decreased in 5 of 8 hallucinators. These results indicate that visual hallucinations in PD are likely to be related to a REM sleep disorder manifested as the appearance of both stage 1–REM during the night and SOREMP in the daytime. © 2003 Movement Disorder Society
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DOI: 10.1002/mds.10439
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ISTEX:761A7232099FEC4B2AE34CB40D32D038844E6288Le document en format XML
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A multiple sleep latency test (MSLT) was performed on 3 hallucinators, and the content of dreams during daytime REM sleep was investigated. The efficacy of clonazepam, a standard treatment choice for REM sleep behavior disorders, was investigated in 8 hallucinators. Nocturnal polysomnograms of the hallucinators showed a higher amount of stage 1–REM sleep with tonic electromyogram (stage 1–REM) than the nonhallucinators, and the reported occurrences of nocturnal hallucinations corresponded with the periods of stage REM or stage 1–REM in most hallucinators. The frequency of sleep onset REM periods (SOREMP) on the MSLT were pathologically high in the hallucinators, and the content of the dreams during the MSLT period was quite similar to their hallucinations. During clonazepam treatment, the frequency of hallucinatory symptoms decreased in 5 of 8 hallucinators. These results indicate that visual hallucinations in PD are likely to be related to a REM sleep disorder manifested as the appearance of both stage 1–REM during the night and SOREMP in the daytime. © 2003 Movement Disorder Society</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Takashi Nomura MD</name><affiliations><json:string>Department of Neurology, Institute of Neurological Sciences, Tottori University Faculty of Medicine, Yonago, Japan</json:string></affiliations></json:item><json:item><name>Yuichi Inoue MD</name><affiliations><json:string>Department of Psychiatry, Juntendo University School of Medicine, Hongo, Tokyo, Japan</json:string></affiliations></json:item><json:item><name>Hidetaka Mitani PhD</name><affiliations><json:string>Department of Psychiatry, Tottori University, Faculty of Medicine, Yonago, Japan</json:string></affiliations></json:item><json:item><name>Ryuzo Kawahara MD</name><affiliations><json:string>Department of Psychiatry, Tottori University, Faculty of Medicine, Yonago, Japan</json:string></affiliations></json:item><json:item><name>Masahiro Miyake MD</name><affiliations><json:string>Department of Neurology, Institute of Neurological Sciences, Tottori University Faculty of Medicine, Yonago, Japan</json:string></affiliations></json:item><json:item><name>Kenji Nakashima MD</name><affiliations><json:string>Department of Neurology, Institute of Neurological Sciences, Tottori University Faculty of Medicine, Yonago, Japan</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>REM sleep disorder</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>polysomnography</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>clonazepam</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>hallucination</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item></subject><language><json:string>eng</json:string></language><abstract>To clarify whether visual hallucinations in patients with Parkinson's disease (PD) are related to rapid eye movement (REM) sleep, nocturnal polysomnographic variables were compared between a group with hallucinations (hallucinators, n = 14) and a group without hallucinations (nonhallucinators, n = 8). A multiple sleep latency test (MSLT) was performed on 3 hallucinators, and the content of dreams during daytime REM sleep was investigated. The efficacy of clonazepam, a standard treatment choice for REM sleep behavior disorders, was investigated in 8 hallucinators. Nocturnal polysomnograms of the hallucinators showed a higher amount of stage 1–REM sleep with tonic electromyogram (stage 1–REM) than the nonhallucinators, and the reported occurrences of nocturnal hallucinations corresponded with the periods of stage REM or stage 1–REM in most hallucinators. The frequency of sleep onset REM periods (SOREMP) on the MSLT were pathologically high in the hallucinators, and the content of the dreams during the MSLT period was quite similar to their hallucinations. During clonazepam treatment, the frequency of hallucinatory symptoms decreased in 5 of 8 hallucinators. 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A multiple sleep latency test (MSLT) was performed on 3 hallucinators, and the content of dreams during daytime REM sleep was investigated. The efficacy of clonazepam, a standard treatment choice for REM sleep behavior disorders, was investigated in 8 hallucinators. Nocturnal polysomnograms of the hallucinators showed a higher amount of stage 1–REM sleep with tonic electromyogram (stage 1–REM) than the nonhallucinators, and the reported occurrences of nocturnal hallucinations corresponded with the periods of stage REM or stage 1–REM in most hallucinators. The frequency of sleep onset REM periods (SOREMP) on the MSLT were pathologically high in the hallucinators, and the content of the dreams during the MSLT period was quite similar to their hallucinations. During clonazepam treatment, the frequency of hallucinatory symptoms decreased in 5 of 8 hallucinators. These results indicate that visual hallucinations in PD are likely to be related to a REM sleep disorder manifested as the appearance of both stage 1–REM during the night and SOREMP in the daytime. © 2003 Movement Disorder Society</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>REM sleep disorder</term></item><item><term>polysomnography</term></item><item><term>clonazepam</term></item><item><term>hallucination</term></item><item><term>Parkinson's disease</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Article category</head><item><term>Brief Report</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2002-04-08">Received</change><change when="2002-11-27">Registration</change><change when="2003-07">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/761A7232099FEC4B2AE34CB40D32D038844E6288/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1531-8257</doi><issn type="print">0885-3185</issn><issn type="electronic">1531-8257</issn><idGroup><id type="product" value="MDS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOVEMENT DISORDERS">Movement Disorders</title><title type="short">Mov. 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href="file:MDS.MDS10439.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="1"></count><count type="tableTotal" number="4"></count><count type="referenceTotal" number="28"></count><count type="wordTotal" number="4152"></count></countGroup><titleGroup><title type="main" xml:lang="en">Visual hallucinations as REM sleep behavior disorders in patients with Parkinson's disease</title><title type="short" xml:lang="en">Visual Hallucinations as RBD in PD</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Takashi</givenNames><familyName>Nomura</familyName><degrees>MD</degrees></personName><contactDetails><email>ZVS03523@nifty.ne.jp</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Yuichi</givenNames><familyName>Inoue</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af3"><personName><givenNames>Hidetaka</givenNames><familyName>Mitani</familyName><degrees>PhD</degrees></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af3"><personName><givenNames>Ryuzo</givenNames><familyName>Kawahara</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Masahiro</givenNames><familyName>Miyake</familyName><degrees>MD</degrees></personName></creator><creator xml:id="au6" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Kenji</givenNames><familyName>Nakashima</familyName><degrees>MD</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="JP" type="organization"><unparsedAffiliation>Department of Neurology, Institute of Neurological Sciences, Tottori University Faculty of Medicine, Yonago, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="JP" type="organization"><unparsedAffiliation>Department of Psychiatry, Juntendo University School of Medicine, Hongo, Tokyo, Japan</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="JP" type="organization"><unparsedAffiliation>Department of Psychiatry, Tottori University, Faculty of Medicine, Yonago, Japan</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">REM sleep disorder</keyword><keyword xml:id="kwd2">polysomnography</keyword><keyword xml:id="kwd3">clonazepam</keyword><keyword xml:id="kwd4">hallucination</keyword><keyword xml:id="kwd5">Parkinson's disease</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>To clarify whether visual hallucinations in patients with Parkinson's disease (PD) are related to rapid eye movement (REM) sleep, nocturnal polysomnographic variables were compared between a group with hallucinations (hallucinators, n = 14) and a group without hallucinations (nonhallucinators, n = 8). A multiple sleep latency test (MSLT) was performed on 3 hallucinators, and the content of dreams during daytime REM sleep was investigated. The efficacy of clonazepam, a standard treatment choice for REM sleep behavior disorders, was investigated in 8 hallucinators. Nocturnal polysomnograms of the hallucinators showed a higher amount of stage 1–REM sleep with tonic electromyogram (stage 1–REM) than the nonhallucinators, and the reported occurrences of nocturnal hallucinations corresponded with the periods of stage REM or stage 1–REM in most hallucinators. The frequency of sleep onset REM periods (SOREMP) on the MSLT were pathologically high in the hallucinators, and the content of the dreams during the MSLT period was quite similar to their hallucinations. During clonazepam treatment, the frequency of hallucinatory symptoms decreased in 5 of 8 hallucinators. These results indicate that visual hallucinations in PD are likely to be related to a REM sleep disorder manifested as the appearance of both stage 1–REM during the night and SOREMP in the daytime. © 2003 Movement Disorder Society</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><!--Version 0.6 générée le 4-12-2015--><mods version="3.6"><titleInfo lang="en"><title>Visual hallucinations as REM sleep behavior disorders in patients with Parkinson's disease</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Visual Hallucinations as RBD in PD</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Visual hallucinations as REM sleep behavior disorders in patients with Parkinson's disease</title></titleInfo><name type="personal"><namePart type="given">Takashi</namePart><namePart type="family">Nomura</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Institute of Neurological Sciences, Tottori University Faculty of Medicine, Yonago, Japan</affiliation><description>Correspondence: Department of Neurology, Institute of Neurological Sciences, Tottori University, Faculty of Medicine, 36‐1 Nishimachi, Yonago 683‐8504, Japan</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yuichi</namePart><namePart type="family">Inoue</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Psychiatry, Juntendo University School of Medicine, Hongo, Tokyo, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hidetaka</namePart><namePart type="family">Mitani</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>Department of Psychiatry, Tottori University, Faculty of Medicine, Yonago, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ryuzo</namePart><namePart type="family">Kawahara</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Psychiatry, Tottori University, Faculty of Medicine, Yonago, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Masahiro</namePart><namePart type="family">Miyake</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Institute of Neurological Sciences, Tottori University Faculty of Medicine, Yonago, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Kenji</namePart><namePart type="family">Nakashima</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>Department of Neurology, Institute of Neurological Sciences, Tottori University Faculty of Medicine, Yonago, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre authority="originalCategForm">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2003-07</dateIssued><dateCaptured encoding="w3cdtf">2002-04-08</dateCaptured><dateValid encoding="w3cdtf">2002-11-27</dateValid><copyrightDate encoding="w3cdtf">2003</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">1</extent><extent unit="tables">4</extent><extent unit="references">28</extent><extent unit="words">4152</extent></physicalDescription><abstract lang="en">To clarify whether visual hallucinations in patients with Parkinson's disease (PD) are related to rapid eye movement (REM) sleep, nocturnal polysomnographic variables were compared between a group with hallucinations (hallucinators, n = 14) and a group without hallucinations (nonhallucinators, n = 8). A multiple sleep latency test (MSLT) was performed on 3 hallucinators, and the content of dreams during daytime REM sleep was investigated. The efficacy of clonazepam, a standard treatment choice for REM sleep behavior disorders, was investigated in 8 hallucinators. Nocturnal polysomnograms of the hallucinators showed a higher amount of stage 1–REM sleep with tonic electromyogram (stage 1–REM) than the nonhallucinators, and the reported occurrences of nocturnal hallucinations corresponded with the periods of stage REM or stage 1–REM in most hallucinators. The frequency of sleep onset REM periods (SOREMP) on the MSLT were pathologically high in the hallucinators, and the content of the dreams during the MSLT period was quite similar to their hallucinations. During clonazepam treatment, the frequency of hallucinatory symptoms decreased in 5 of 8 hallucinators. These results indicate that visual hallucinations in PD are likely to be related to a REM sleep disorder manifested as the appearance of both stage 1–REM during the night and SOREMP in the daytime. © 2003 Movement Disorder Society</abstract><subject lang="en"><genre>Keywords</genre><topic>REM sleep disorder</topic><topic>polysomnography</topic><topic>clonazepam</topic><topic>hallucination</topic><topic>Parkinson's disease</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. Disord.</title></titleInfo><subject><genre>article category</genre><topic>Brief Report</topic></subject><identifier type="ISSN">0885-3185</identifier><identifier type="eISSN">1531-8257</identifier><identifier type="DOI">10.1002/(ISSN)1531-8257</identifier><identifier type="PublisherID">MDS</identifier><part><date>2003</date><detail type="volume"><caption>vol.</caption><number>18</number></detail><detail type="issue"><caption>no.</caption><number>7</number></detail><extent unit="pages"><start>812</start><end>817</end><total>6</total></extent></part></relatedItem><identifier type="istex">761A7232099FEC4B2AE34CB40D32D038844E6288</identifier><identifier type="DOI">10.1002/mds.10439</identifier><identifier type="ArticleID">MDS10439</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2003 Movement Disorder Society</accessCondition><recordInfo><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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