Serveur d'exploration MERS

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Middle East respiratory syndrome (MERS)

Identifieur interne : 001429 ( Pmc/Curation ); précédent : 001428; suivant : 001430

Middle East respiratory syndrome (MERS)

Auteurs : Cheston B. Cunha [États-Unis] ; Steven M. Opal [États-Unis]

Source :

RBID : PMC:4139405

Abstract

Coronaviruses have traditionally been associated with mild upper respiratory tract infections throughout the world. In the fall of 2002, a new coronavirus emerged in in Asia causing severe viral pneumonia, i.e., severe acute respiratory syndrome (SARS). Nearly a decade following the SARS epidemic, a new coronavirus causing severe viral pneumonia has emerged, i.e., middle east respiratory syndrome (MERS). Since the initial case of MERS-CoV occurred in June of 2012 in Saudi Arabia there have been 688 confirmed cases and 282 deaths in 20 countries.

 

Although both SARS and MERS are caused by coronaviruses, SARS was characterized by efficient human transmission and relatively low mortality rate. In contrast, MERS is relatively inefficiently transmitted to humans but has a high mortality rate. Given the potential overlap in presentation and manifestation, it is important to understand the clinical and epidemiologic differences between MERS, SARS and influenza.


Url:
DOI: 10.4161/viru.32077
PubMed: 25089913
PubMed Central: 4139405

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Links to Exploration step

PMC:4139405

Le document en format XML

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<p>Although both SARS and MERS are caused by coronaviruses, SARS was characterized by efficient human transmission and relatively low mortality rate. In contrast, MERS is relatively inefficiently transmitted to humans but has a high mortality rate. Given the potential overlap in presentation and manifestation, it is important to understand the clinical and epidemiologic differences between MERS, SARS and influenza.</p>
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<name sortKey="Cotten, M" uniqKey="Cotten M">M Cotten</name>
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<name sortKey="Watson, Sj" uniqKey="Watson S">SJ Watson</name>
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<name sortKey="Kellam, P" uniqKey="Kellam P">P Kellam</name>
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<author>
<name sortKey="Zumla, A" uniqKey="Zumla A">A Zumla</name>
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<name sortKey="Assiri, A" uniqKey="Assiri A">A Assiri</name>
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<author>
<name sortKey="Rabeeah, Aa" uniqKey="Rabeeah A">AA Rabeeah</name>
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<author>
<name sortKey="Al Tawfiq, Ja" uniqKey="Al Tawfiq J">JA Al-Tawfiq</name>
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<name sortKey="Stephens, Gm" uniqKey="Stephens G">GM Stephens</name>
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<name sortKey="Cunha, Ba" uniqKey="Cunha B">BA Cunha</name>
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<pmc article-type="review-article">
<pmc-dir>properties open_access</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Virulence</journal-id>
<journal-id journal-id-type="iso-abbrev">Virulence</journal-id>
<journal-id journal-id-type="publisher-id">VIRU</journal-id>
<journal-title-group>
<journal-title>Virulence</journal-title>
</journal-title-group>
<issn pub-type="ppub">2150-5594</issn>
<issn pub-type="epub">2150-5608</issn>
<publisher>
<publisher-name>Landes Bioscience</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">25089913</article-id>
<article-id pub-id-type="pmc">4139405</article-id>
<article-id pub-id-type="publisher-id">2014VIRULENCE0095</article-id>
<article-id pub-id-type="doi">10.4161/viru.32077</article-id>
<article-id pub-id-type="pii">32077</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Review</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Middle East respiratory syndrome (MERS)</article-title>
<subtitle>A new zoonotic viral pneumonia</subtitle>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Cunha</surname>
<given-names>Cheston B</given-names>
</name>
<xref ref-type="aff" rid="A1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="A2">
<sup>2</sup>
</xref>
<xref ref-type="corresp" rid="cor1">*</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Opal</surname>
<given-names>Steven M</given-names>
</name>
<xref ref-type="aff" rid="A2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="A3">
<sup>3</sup>
</xref>
</contrib>
<aff id="A1">
<label>1</label>
Division of Infectious Disease; Rhode Island Hospital and The Miriam Hospital; Providence, RI USA</aff>
<aff id="A2">
<label>2</label>
Division of Infectious Disease; Brown University Alpert School of Medicine; Providence, RI USA</aff>
<aff id="A3">
<label>3</label>
Division of Infectious Disease; Memorial Hospital; Pawtucket, RI USA</aff>
</contrib-group>
<author-notes>
<corresp id="cor1">
<label>*</label>
Correspondence to: Cheston B Cunha, Email:
<email xlink:href="ccunha@lifespan.org">ccunha@lifespan.org</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub">
<day>15</day>
<month>8</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="epub">
<day>04</day>
<month>8</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="pmc-release">
<day>15</day>
<month>8</month>
<year>2015</year>
</pub-date>
<pmc-comment> PMC Release delay is 12 months and 0 days and was based on the . </pmc-comment>
<volume>5</volume>
<issue>6</issue>
<fpage>650</fpage>
<lpage>654</lpage>
<history>
<date date-type="received">
<day>16</day>
<month>7</month>
<year>2014</year>
</date>
<date date-type="accepted">
<day>19</day>
<month>7</month>
<year>2014</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright © 2014 Landes Bioscience</copyright-statement>
<copyright-year>2014</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">
<license-p>This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.</license-p>
</license>
</permissions>
<abstract>
<p>Coronaviruses have traditionally been associated with mild upper respiratory tract infections throughout the world. In the fall of 2002, a new coronavirus emerged in in Asia causing severe viral pneumonia, i.e., severe acute respiratory syndrome (SARS). Nearly a decade following the SARS epidemic, a new coronavirus causing severe viral pneumonia has emerged, i.e., middle east respiratory syndrome (MERS). Since the initial case of MERS-CoV occurred in June of 2012 in Saudi Arabia there have been 688 confirmed cases and 282 deaths in 20 countries. </p>
<p> </p>
<p>Although both SARS and MERS are caused by coronaviruses, SARS was characterized by efficient human transmission and relatively low mortality rate. In contrast, MERS is relatively inefficiently transmitted to humans but has a high mortality rate. Given the potential overlap in presentation and manifestation, it is important to understand the clinical and epidemiologic differences between MERS, SARS and influenza.</p>
</abstract>
<kwd-group kwd-group-type="author">
<title>Keywords: </title>
<kwd>MERS</kwd>
<kwd>Middle Eastern respiratory syndrome</kwd>
<kwd>coronavirus</kwd>
<kwd>emerging pathogens</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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