The prevalence of Middle East respiratory syndrome coronavirus (MERS‐CoV) antibodies in dromedary camels in Israel
Identifieur interne : 001E51 ( Ncbi/Merge ); précédent : 001E50; suivant : 001E52The prevalence of Middle East respiratory syndrome coronavirus (MERS‐CoV) antibodies in dromedary camels in Israel
Auteurs : Jennifer L. Harcourt ; Nir Rudoler ; Azaibi Tamin ; Eyal Leshem ; Michal Rasis ; Michael Giladi ; Lia M. HaynesSource :
- Zoonoses and Public Health [ 1863-1959 ] ; 2018.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antiviraux (sang), Anticorps neutralisants (sang), Chameaux (virologie), Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie), Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification), Femelle, Infections à coronavirus (médecine vétérinaire), Infections à coronavirus (sang), Infections à coronavirus (virologie), Infections à coronavirus (épidémiologie), Israël, Mâle, Prévalence, Zoonoses (épidémiologie), Études séroépidémiologiques.
- MESH :
- immunologie : Coronavirus du syndrome respiratoire du Moyen-Orient.
- isolement et purification : Coronavirus du syndrome respiratoire du Moyen-Orient.
- médecine vétérinaire : Infections à coronavirus.
- sang : Anticorps antiviraux, Anticorps neutralisants, Infections à coronavirus.
- virologie : Chameaux, Infections à coronavirus.
- épidémiologie : Infections à coronavirus, Zoonoses.
- Animaux, Femelle, Israël, Mâle, Prévalence, Études séroépidémiologiques.
- Wicri :
- geographic : Israël.
English descriptors
- KwdEn :
- Animals, Antibodies, Neutralizing (blood), Antibodies, Viral (blood), Camelus (virology), Coronavirus Infections (blood), Coronavirus Infections (epidemiology), Coronavirus Infections (veterinary), Coronavirus Infections (virology), Female, Israel, Male, Middle East Respiratory Syndrome Coronavirus (immunology), Middle East Respiratory Syndrome Coronavirus (isolation & purification), Prevalence, Seroepidemiologic Studies, Zoonoses (epidemiology).
- MESH :
- chemical , blood : Antibodies, Neutralizing, Antibodies, Viral.
- geographic : Israel.
- blood : Coronavirus Infections.
- epidemiology : Coronavirus Infections, Zoonoses.
- immunology : Middle East Respiratory Syndrome Coronavirus.
- isolation & purification : Middle East Respiratory Syndrome Coronavirus.
- veterinary : Coronavirus Infections.
- virology : Camelus, Coronavirus Infections.
- Animals, Female, Male, Prevalence, Seroepidemiologic Studies.
Abstract
Middle East respiratory syndrome coronavirus, MERS‐CoV, was identified in Saudi Arabia in 2012, and as of January 29, 2018, there were 2,123 laboratory‐confirmed MERS‐CoV cases reported to WHO (WHO, 2018,
Url:
DOI: 10.1111/zph.12482
PubMed: 29855166
PubMed Central: 6274617
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000753
- to stream Pmc, to step Curation: 000753
- to stream Pmc, to step Checkpoint: 000448
- to stream PubMed, to step Corpus: 000881
- to stream PubMed, to step Curation: 000881
- to stream PubMed, to step Checkpoint: 000736
Links to Exploration step
PMC:6274617Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The prevalence of Middle East respiratory syndrome coronavirus (MERS‐CoV) antibodies in dromedary camels in Israel</title>
<author><name sortKey="Harcourt, Jennifer L" sort="Harcourt, Jennifer L" uniqKey="Harcourt J" first="Jennifer L." last="Harcourt">Jennifer L. Harcourt</name>
<affiliation><nlm:aff id="zph12482-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rudoler, Nir" sort="Rudoler, Nir" uniqKey="Rudoler N" first="Nir" last="Rudoler">Nir Rudoler</name>
<affiliation><nlm:aff id="zph12482-aff-0002"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tamin, Azaibi" sort="Tamin, Azaibi" uniqKey="Tamin A" first="Azaibi" last="Tamin">Azaibi Tamin</name>
<affiliation><nlm:aff id="zph12482-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Leshem, Eyal" sort="Leshem, Eyal" uniqKey="Leshem E" first="Eyal" last="Leshem">Eyal Leshem</name>
<affiliation><nlm:aff id="zph12482-aff-0003"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rasis, Michal" sort="Rasis, Michal" uniqKey="Rasis M" first="Michal" last="Rasis">Michal Rasis</name>
<affiliation><nlm:aff id="zph12482-aff-0004"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Giladi, Michael" sort="Giladi, Michael" uniqKey="Giladi M" first="Michael" last="Giladi">Michael Giladi</name>
<affiliation><nlm:aff id="zph12482-aff-0004"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="zph12482-aff-0005"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Haynes, Lia M" sort="Haynes, Lia M" uniqKey="Haynes L" first="Lia M." last="Haynes">Lia M. Haynes</name>
<affiliation><nlm:aff id="zph12482-aff-0006"></nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">29855166</idno>
<idno type="pmc">6274617</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274617</idno>
<idno type="RBID">PMC:6274617</idno>
<idno type="doi">10.1111/zph.12482</idno>
<date when="2018">2018</date>
<idno type="wicri:Area/Pmc/Corpus">000753</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000753</idno>
<idno type="wicri:Area/Pmc/Curation">000753</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000753</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000448</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000448</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:29855166</idno>
<idno type="wicri:Area/PubMed/Corpus">000881</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000881</idno>
<idno type="wicri:Area/PubMed/Curation">000881</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000881</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000736</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000736</idno>
<idno type="wicri:Area/Ncbi/Merge">001E51</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The prevalence of Middle East respiratory syndrome coronavirus (MERS‐CoV) antibodies in dromedary camels in Israel</title>
<author><name sortKey="Harcourt, Jennifer L" sort="Harcourt, Jennifer L" uniqKey="Harcourt J" first="Jennifer L." last="Harcourt">Jennifer L. Harcourt</name>
<affiliation><nlm:aff id="zph12482-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rudoler, Nir" sort="Rudoler, Nir" uniqKey="Rudoler N" first="Nir" last="Rudoler">Nir Rudoler</name>
<affiliation><nlm:aff id="zph12482-aff-0002"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tamin, Azaibi" sort="Tamin, Azaibi" uniqKey="Tamin A" first="Azaibi" last="Tamin">Azaibi Tamin</name>
<affiliation><nlm:aff id="zph12482-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Leshem, Eyal" sort="Leshem, Eyal" uniqKey="Leshem E" first="Eyal" last="Leshem">Eyal Leshem</name>
<affiliation><nlm:aff id="zph12482-aff-0003"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rasis, Michal" sort="Rasis, Michal" uniqKey="Rasis M" first="Michal" last="Rasis">Michal Rasis</name>
<affiliation><nlm:aff id="zph12482-aff-0004"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Giladi, Michael" sort="Giladi, Michael" uniqKey="Giladi M" first="Michael" last="Giladi">Michael Giladi</name>
<affiliation><nlm:aff id="zph12482-aff-0004"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="zph12482-aff-0005"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Haynes, Lia M" sort="Haynes, Lia M" uniqKey="Haynes L" first="Lia M." last="Haynes">Lia M. Haynes</name>
<affiliation><nlm:aff id="zph12482-aff-0006"></nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Zoonoses and Public Health</title>
<idno type="ISSN">1863-1959</idno>
<idno type="eISSN">1863-2378</idno>
<imprint><date when="2018">2018</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Antibodies, Neutralizing (blood)</term>
<term>Antibodies, Viral (blood)</term>
<term>Camelus (virology)</term>
<term>Coronavirus Infections (blood)</term>
<term>Coronavirus Infections (epidemiology)</term>
<term>Coronavirus Infections (veterinary)</term>
<term>Coronavirus Infections (virology)</term>
<term>Female</term>
<term>Israel</term>
<term>Male</term>
<term>Middle East Respiratory Syndrome Coronavirus (immunology)</term>
<term>Middle East Respiratory Syndrome Coronavirus (isolation & purification)</term>
<term>Prevalence</term>
<term>Seroepidemiologic Studies</term>
<term>Zoonoses (epidemiology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Anticorps antiviraux (sang)</term>
<term>Anticorps neutralisants (sang)</term>
<term>Chameaux (virologie)</term>
<term>Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie)</term>
<term>Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification)</term>
<term>Femelle</term>
<term>Infections à coronavirus (médecine vétérinaire)</term>
<term>Infections à coronavirus (sang)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Infections à coronavirus (épidémiologie)</term>
<term>Israël</term>
<term>Mâle</term>
<term>Prévalence</term>
<term>Zoonoses (épidémiologie)</term>
<term>Études séroépidémiologiques</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Neutralizing</term>
<term>Antibodies, Viral</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Israel</term>
</keywords>
<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Coronavirus Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Zoonoses</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term>
</keywords>
<keywords scheme="MESH" qualifier="médecine vétérinaire" xml:lang="fr"><term>Infections à coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antiviraux</term>
<term>Anticorps neutralisants</term>
<term>Infections à coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Coronavirus Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Chameaux</term>
<term>Infections à coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Camelus</term>
<term>Coronavirus Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Zoonoses</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Female</term>
<term>Male</term>
<term>Prevalence</term>
<term>Seroepidemiologic Studies</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Femelle</term>
<term>Israël</term>
<term>Mâle</term>
<term>Prévalence</term>
<term>Études séroépidémiologiques</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Israël</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><title>Abstract</title>
<p>Middle East respiratory syndrome coronavirus, MERS‐CoV, was identified in Saudi Arabia in 2012, and as of January 29, 2018, there were 2,123 laboratory‐confirmed MERS‐CoV cases reported to WHO (WHO, 2018, <ext-link ext-link-type="uri" xlink:href="https://www.who.int/emergencies/mers-cov/en/">https://www.who.int/emergencies/mers-cov/en/</ext-link>
). Multiple studies suggest that dromedary camels are a source for human MERS‐CoV infection. MERS‐CoV‐specific antibodies have been detected in the serum of dromedary camels across Northern Africa and across the Arabian Peninsula. Israel's geographic location places Israel at risk for MERS‐CoV infection. To date, MERS‐CoV‐related illness has not been reported and the burden of MERS‐CoV infection in the Israeli population is unknown. The seroprevalence of MERS‐CoV‐specific antibodies in Israeli dromedary camels is unknown. The objective of this study was to determine the prevalence of MERS‐CoV seropositivity in dromedary camels in Israel. The prevalence of MERS‐CoV antibodies in Israeli camels was examined in 71 camel sera collected from four farms across Israel by MERS‐CoV‐specific microneutralization (Mnt) assay and confirmed by MERS‐CoV‐specific immunofluorescence assay (IFA). Although this study cannot rule out potential antibody cross‐reactivity by IFA, the presence of bovine coronavirus‐specific antibodies do not appear to impact detection of MERS‐CoV antibodies by Mnt. MERS‐CoV neutralizing antibodies were detectable in 51 (71.8%) camel sera, and no association was observed between the presence of neutralizing antibodies and camel age or gender. These findings extend the known range of MERS‐CoV circulation in Middle Eastern camels. The high rate of MERS‐CoV‐specific antibody seropositivity in dromedary camels in the absence of any reported human MERS cases suggests that there is still much to be learned about the dynamics of camel‐to‐human transmission of MERS‐CoV.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<double pmid="29855166"><pmc><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The prevalence of Middle East respiratory syndrome coronavirus (MERS‐CoV) antibodies in dromedary camels in Israel</title>
<author><name sortKey="Harcourt, Jennifer L" sort="Harcourt, Jennifer L" uniqKey="Harcourt J" first="Jennifer L." last="Harcourt">Jennifer L. Harcourt</name>
<affiliation><nlm:aff id="zph12482-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rudoler, Nir" sort="Rudoler, Nir" uniqKey="Rudoler N" first="Nir" last="Rudoler">Nir Rudoler</name>
<affiliation><nlm:aff id="zph12482-aff-0002"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tamin, Azaibi" sort="Tamin, Azaibi" uniqKey="Tamin A" first="Azaibi" last="Tamin">Azaibi Tamin</name>
<affiliation><nlm:aff id="zph12482-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Leshem, Eyal" sort="Leshem, Eyal" uniqKey="Leshem E" first="Eyal" last="Leshem">Eyal Leshem</name>
<affiliation><nlm:aff id="zph12482-aff-0003"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rasis, Michal" sort="Rasis, Michal" uniqKey="Rasis M" first="Michal" last="Rasis">Michal Rasis</name>
<affiliation><nlm:aff id="zph12482-aff-0004"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Giladi, Michael" sort="Giladi, Michael" uniqKey="Giladi M" first="Michael" last="Giladi">Michael Giladi</name>
<affiliation><nlm:aff id="zph12482-aff-0004"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="zph12482-aff-0005"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Haynes, Lia M" sort="Haynes, Lia M" uniqKey="Haynes L" first="Lia M." last="Haynes">Lia M. Haynes</name>
<affiliation><nlm:aff id="zph12482-aff-0006"></nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">29855166</idno>
<idno type="pmc">6274617</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274617</idno>
<idno type="RBID">PMC:6274617</idno>
<idno type="doi">10.1111/zph.12482</idno>
<date when="2018">2018</date>
<idno type="wicri:Area/Pmc/Corpus">000753</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000753</idno>
<idno type="wicri:Area/Pmc/Curation">000753</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000753</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000448</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000448</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The prevalence of Middle East respiratory syndrome coronavirus (MERS‐CoV) antibodies in dromedary camels in Israel</title>
<author><name sortKey="Harcourt, Jennifer L" sort="Harcourt, Jennifer L" uniqKey="Harcourt J" first="Jennifer L." last="Harcourt">Jennifer L. Harcourt</name>
<affiliation><nlm:aff id="zph12482-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rudoler, Nir" sort="Rudoler, Nir" uniqKey="Rudoler N" first="Nir" last="Rudoler">Nir Rudoler</name>
<affiliation><nlm:aff id="zph12482-aff-0002"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tamin, Azaibi" sort="Tamin, Azaibi" uniqKey="Tamin A" first="Azaibi" last="Tamin">Azaibi Tamin</name>
<affiliation><nlm:aff id="zph12482-aff-0001"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Leshem, Eyal" sort="Leshem, Eyal" uniqKey="Leshem E" first="Eyal" last="Leshem">Eyal Leshem</name>
<affiliation><nlm:aff id="zph12482-aff-0003"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Rasis, Michal" sort="Rasis, Michal" uniqKey="Rasis M" first="Michal" last="Rasis">Michal Rasis</name>
<affiliation><nlm:aff id="zph12482-aff-0004"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Giladi, Michael" sort="Giladi, Michael" uniqKey="Giladi M" first="Michael" last="Giladi">Michael Giladi</name>
<affiliation><nlm:aff id="zph12482-aff-0004"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="zph12482-aff-0005"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Haynes, Lia M" sort="Haynes, Lia M" uniqKey="Haynes L" first="Lia M." last="Haynes">Lia M. Haynes</name>
<affiliation><nlm:aff id="zph12482-aff-0006"></nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Zoonoses and Public Health</title>
<idno type="ISSN">1863-1959</idno>
<idno type="eISSN">1863-2378</idno>
<imprint><date when="2018">2018</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><title>Abstract</title>
<p>Middle East respiratory syndrome coronavirus, MERS‐CoV, was identified in Saudi Arabia in 2012, and as of January 29, 2018, there were 2,123 laboratory‐confirmed MERS‐CoV cases reported to WHO (WHO, 2018, <ext-link ext-link-type="uri" xlink:href="https://www.who.int/emergencies/mers-cov/en/">https://www.who.int/emergencies/mers-cov/en/</ext-link>
). Multiple studies suggest that dromedary camels are a source for human MERS‐CoV infection. MERS‐CoV‐specific antibodies have been detected in the serum of dromedary camels across Northern Africa and across the Arabian Peninsula. Israel's geographic location places Israel at risk for MERS‐CoV infection. To date, MERS‐CoV‐related illness has not been reported and the burden of MERS‐CoV infection in the Israeli population is unknown. The seroprevalence of MERS‐CoV‐specific antibodies in Israeli dromedary camels is unknown. The objective of this study was to determine the prevalence of MERS‐CoV seropositivity in dromedary camels in Israel. The prevalence of MERS‐CoV antibodies in Israeli camels was examined in 71 camel sera collected from four farms across Israel by MERS‐CoV‐specific microneutralization (Mnt) assay and confirmed by MERS‐CoV‐specific immunofluorescence assay (IFA). Although this study cannot rule out potential antibody cross‐reactivity by IFA, the presence of bovine coronavirus‐specific antibodies do not appear to impact detection of MERS‐CoV antibodies by Mnt. MERS‐CoV neutralizing antibodies were detectable in 51 (71.8%) camel sera, and no association was observed between the presence of neutralizing antibodies and camel age or gender. These findings extend the known range of MERS‐CoV circulation in Middle Eastern camels. The high rate of MERS‐CoV‐specific antibody seropositivity in dromedary camels in the absence of any reported human MERS cases suggests that there is still much to be learned about the dynamics of camel‐to‐human transmission of MERS‐CoV.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
</listBibl>
</div1>
</back>
</TEI>
</pmc>
<pubmed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The prevalence of Middle East respiratory syndrome coronavirus (MERS-CoV) antibodies in dromedary camels in Israel.</title>
<author><name sortKey="Harcourt, Jennifer L" sort="Harcourt, Jennifer L" uniqKey="Harcourt J" first="Jennifer L" last="Harcourt">Jennifer L. Harcourt</name>
<affiliation wicri:level="1"><nlm:affiliation>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Gastroenteritis and Respiratory Viruses Laboratory Branch, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia.</nlm:affiliation>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Gastroenteritis and Respiratory Viruses Laboratory Branch, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea>
<wicri:noRegion>Atlanta</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rudoler, Nir" sort="Rudoler, Nir" uniqKey="Rudoler N" first="Nir" last="Rudoler">Nir Rudoler</name>
<affiliation wicri:level="1"><nlm:affiliation>Koret School of Veterinary Medicine, Faculty of Agriculture, Hebrew University, Rehovot, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Koret School of Veterinary Medicine, Faculty of Agriculture, Hebrew University, Rehovot</wicri:regionArea>
<wicri:noRegion>Rehovot</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tamin, Azaibi" sort="Tamin, Azaibi" uniqKey="Tamin A" first="Azaibi" last="Tamin">Azaibi Tamin</name>
<affiliation wicri:level="1"><nlm:affiliation>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Gastroenteritis and Respiratory Viruses Laboratory Branch, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia.</nlm:affiliation>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Gastroenteritis and Respiratory Viruses Laboratory Branch, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea>
<wicri:noRegion>Atlanta</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Leshem, Eyal" sort="Leshem, Eyal" uniqKey="Leshem E" first="Eyal" last="Leshem">Eyal Leshem</name>
<affiliation wicri:level="1"><nlm:affiliation>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Epidemiology Branch, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia.</nlm:affiliation>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Epidemiology Branch, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea>
<wicri:noRegion>Atlanta</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rasis, Michal" sort="Rasis, Michal" uniqKey="Rasis M" first="Michal" last="Rasis">Michal Rasis</name>
<affiliation wicri:level="1"><nlm:affiliation>Bernard Pridan Laboratory for Molecular Biology of Infectious Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Bernard Pridan Laboratory for Molecular Biology of Infectious Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv</wicri:regionArea>
<wicri:noRegion>Tel Aviv</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Giladi, Michael" sort="Giladi, Michael" uniqKey="Giladi M" first="Michael" last="Giladi">Michael Giladi</name>
<affiliation wicri:level="1"><nlm:affiliation>Bernard Pridan Laboratory for Molecular Biology of Infectious Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Bernard Pridan Laboratory for Molecular Biology of Infectious Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv</wicri:regionArea>
<wicri:noRegion>Tel Aviv</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Haynes, Lia M" sort="Haynes, Lia M" uniqKey="Haynes L" first="Lia M" last="Haynes">Lia M. Haynes</name>
<affiliation wicri:level="1"><nlm:affiliation>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia.</nlm:affiliation>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea>
<wicri:noRegion>Atlanta</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2018">2018</date>
<idno type="RBID">pubmed:29855166</idno>
<idno type="pmid">29855166</idno>
<idno type="doi">10.1111/zph.12482</idno>
<idno type="wicri:Area/PubMed/Corpus">000881</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000881</idno>
<idno type="wicri:Area/PubMed/Curation">000881</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000881</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000736</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000736</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">The prevalence of Middle East respiratory syndrome coronavirus (MERS-CoV) antibodies in dromedary camels in Israel.</title>
<author><name sortKey="Harcourt, Jennifer L" sort="Harcourt, Jennifer L" uniqKey="Harcourt J" first="Jennifer L" last="Harcourt">Jennifer L. Harcourt</name>
<affiliation wicri:level="1"><nlm:affiliation>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Gastroenteritis and Respiratory Viruses Laboratory Branch, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia.</nlm:affiliation>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Gastroenteritis and Respiratory Viruses Laboratory Branch, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea>
<wicri:noRegion>Atlanta</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rudoler, Nir" sort="Rudoler, Nir" uniqKey="Rudoler N" first="Nir" last="Rudoler">Nir Rudoler</name>
<affiliation wicri:level="1"><nlm:affiliation>Koret School of Veterinary Medicine, Faculty of Agriculture, Hebrew University, Rehovot, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Koret School of Veterinary Medicine, Faculty of Agriculture, Hebrew University, Rehovot</wicri:regionArea>
<wicri:noRegion>Rehovot</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tamin, Azaibi" sort="Tamin, Azaibi" uniqKey="Tamin A" first="Azaibi" last="Tamin">Azaibi Tamin</name>
<affiliation wicri:level="1"><nlm:affiliation>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Gastroenteritis and Respiratory Viruses Laboratory Branch, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia.</nlm:affiliation>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Gastroenteritis and Respiratory Viruses Laboratory Branch, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea>
<wicri:noRegion>Atlanta</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Leshem, Eyal" sort="Leshem, Eyal" uniqKey="Leshem E" first="Eyal" last="Leshem">Eyal Leshem</name>
<affiliation wicri:level="1"><nlm:affiliation>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Epidemiology Branch, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia.</nlm:affiliation>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Epidemiology Branch, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea>
<wicri:noRegion>Atlanta</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rasis, Michal" sort="Rasis, Michal" uniqKey="Rasis M" first="Michal" last="Rasis">Michal Rasis</name>
<affiliation wicri:level="1"><nlm:affiliation>Bernard Pridan Laboratory for Molecular Biology of Infectious Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Bernard Pridan Laboratory for Molecular Biology of Infectious Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv</wicri:regionArea>
<wicri:noRegion>Tel Aviv</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Giladi, Michael" sort="Giladi, Michael" uniqKey="Giladi M" first="Michael" last="Giladi">Michael Giladi</name>
<affiliation wicri:level="1"><nlm:affiliation>Bernard Pridan Laboratory for Molecular Biology of Infectious Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Bernard Pridan Laboratory for Molecular Biology of Infectious Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv</wicri:regionArea>
<wicri:noRegion>Tel Aviv</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Haynes, Lia M" sort="Haynes, Lia M" uniqKey="Haynes L" first="Lia M" last="Haynes">Lia M. Haynes</name>
<affiliation wicri:level="1"><nlm:affiliation>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia.</nlm:affiliation>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>National Center for Immunization and Respiratory Diseases, Division of Viral Diseases, Centers for Disease Control and Prevention (CDC), Atlanta</wicri:regionArea>
<wicri:noRegion>Atlanta</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Zoonoses and public health</title>
<idno type="eISSN">1863-2378</idno>
<imprint><date when="2018" type="published">2018</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Antibodies, Neutralizing (blood)</term>
<term>Antibodies, Viral (blood)</term>
<term>Camelus (virology)</term>
<term>Coronavirus Infections (blood)</term>
<term>Coronavirus Infections (epidemiology)</term>
<term>Coronavirus Infections (veterinary)</term>
<term>Coronavirus Infections (virology)</term>
<term>Female</term>
<term>Israel</term>
<term>Male</term>
<term>Middle East Respiratory Syndrome Coronavirus (immunology)</term>
<term>Middle East Respiratory Syndrome Coronavirus (isolation & purification)</term>
<term>Prevalence</term>
<term>Seroepidemiologic Studies</term>
<term>Zoonoses (epidemiology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Anticorps antiviraux (sang)</term>
<term>Anticorps neutralisants (sang)</term>
<term>Chameaux (virologie)</term>
<term>Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie)</term>
<term>Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification)</term>
<term>Femelle</term>
<term>Infections à coronavirus (médecine vétérinaire)</term>
<term>Infections à coronavirus (sang)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Infections à coronavirus (épidémiologie)</term>
<term>Israël</term>
<term>Mâle</term>
<term>Prévalence</term>
<term>Zoonoses (épidémiologie)</term>
<term>Études séroépidémiologiques</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Neutralizing</term>
<term>Antibodies, Viral</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Israel</term>
</keywords>
<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Coronavirus Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Zoonoses</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term>
</keywords>
<keywords scheme="MESH" qualifier="médecine vétérinaire" xml:lang="fr"><term>Infections à coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antiviraux</term>
<term>Anticorps neutralisants</term>
<term>Infections à coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Coronavirus Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Chameaux</term>
<term>Infections à coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Camelus</term>
<term>Coronavirus Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Zoonoses</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Female</term>
<term>Male</term>
<term>Prevalence</term>
<term>Seroepidemiologic Studies</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Femelle</term>
<term>Israël</term>
<term>Mâle</term>
<term>Prévalence</term>
<term>Études séroépidémiologiques</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Israël</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Middle East respiratory syndrome coronavirus, MERS-CoV, was identified in Saudi Arabia in 2012, and as of January 29, 2018, there were 2,123 laboratory-confirmed MERS-CoV cases reported to WHO (WHO, 2018, https://www.who.int/emergencies/mers-cov/en/). Multiple studies suggest that dromedary camels are a source for human MERS-CoV infection. MERS-CoV-specific antibodies have been detected in the serum of dromedary camels across Northern Africa and across the Arabian Peninsula. Israel's geographic location places Israel at risk for MERS-CoV infection. To date, MERS-CoV-related illness has not been reported and the burden of MERS-CoV infection in the Israeli population is unknown. The seroprevalence of MERS-CoV-specific antibodies in Israeli dromedary camels is unknown. The objective of this study was to determine the prevalence of MERS-CoV seropositivity in dromedary camels in Israel. The prevalence of MERS-CoV antibodies in Israeli camels was examined in 71 camel sera collected from four farms across Israel by MERS-CoV-specific microneutralization (Mnt) assay and confirmed by MERS-CoV-specific immunofluorescence assay (IFA). Although this study cannot rule out potential antibody cross-reactivity by IFA, the presence of bovine coronavirus-specific antibodies do not appear to impact detection of MERS-CoV antibodies by Mnt. MERS-CoV neutralizing antibodies were detectable in 51 (71.8%) camel sera, and no association was observed between the presence of neutralizing antibodies and camel age or gender. These findings extend the known range of MERS-CoV circulation in Middle Eastern camels. The high rate of MERS-CoV-specific antibody seropositivity in dromedary camels in the absence of any reported human MERS cases suggests that there is still much to be learned about the dynamics of camel-to-human transmission of MERS-CoV.</div>
</front>
</TEI>
</pubmed>
</double>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001E51 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 001E51 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= MersV1 |flux= Ncbi |étape= Merge |type= RBID |clé= PMC:6274617 |texte= The prevalence of Middle East respiratory syndrome coronavirus (MERS‐CoV) antibodies in dromedary camels in Israel }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:29855166" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \ | NlmPubMed2Wicri -a MersV1
![]() | This area was generated with Dilib version V0.6.33. | ![]() |