Use of the Human Coronavirus 2012 (MERS) GeneSig kit for MERS-CoV detection.
Identifieur interne : 002799 ( Ncbi/Curation ); précédent : 002798; suivant : 002800Use of the Human Coronavirus 2012 (MERS) GeneSig kit for MERS-CoV detection.
Auteurs : Rouba Hoteit [Liban] ; Dina Shammaa [Liban] ; Rami Mahfouz [Liban]Source :
- Gene reports [ 2452-0144 ] ; 2016.
Abstract
Mortality due to MERS-CoV infection is common especially among immunocompromised patients. The pathogenesis and the transmission mode of this virus are still not well understood. The name of the virus is derived from the area of its appearance and the genomic sequence that was used in the development of qRT-PCR assays for MERS-CoV detection was retrieved from the first detected case isolate. The employed assays target various regions including the area upstream of the envelope gene (upE) that is used for screening and the open reading frames (ORF) 1a and 1b used for confirmation.
DOI: 10.1016/j.genrep.2016.04.004
PubMed: 32289095
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