Trowel: a fast and accurate error correction module for Illumina sequencing reads.
Identifieur interne : 000E53 ( Ncbi/Checkpoint ); précédent : 000E52; suivant : 000E54Trowel: a fast and accurate error correction module for Illumina sequencing reads.
Auteurs : Eun-Cheon Lim [Allemagne] ; Jonas Müller [Allemagne] ; Jörg Hagmann [Allemagne] ; Stefan R. Henz [Allemagne] ; Sang-Tae Kim [Allemagne] ; Detlef Weigel [Allemagne]Source :
- Bioinformatics (Oxford, England) [ 1367-4811 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- methods : High-Throughput Nucleotide Sequencing.
- Algorithms, Software.
Abstract
The ability to accurately read the order of nucleotides in DNA and RNA is fundamental for modern biology. Errors in next-generation sequencing can lead to many artifacts, from erroneous genome assemblies to mistaken inferences about RNA editing. Uneven coverage in datasets also contributes to false corrections.
DOI: 10.1093/bioinformatics/btu513
PubMed: 25075116
Affiliations:
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<front><div type="abstract" xml:lang="en">The ability to accurately read the order of nucleotides in DNA and RNA is fundamental for modern biology. Errors in next-generation sequencing can lead to many artifacts, from erroneous genome assemblies to mistaken inferences about RNA editing. Uneven coverage in datasets also contributes to false corrections.</div>
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