LymphedemaV1, Main, Exploration, bibRecord, 004E20

In Vivo Flow Cytometry: A Horizon of Opportunities

Identifieur interne : 004E20 ( Main/Exploration ); précédent : 004E19; suivant : 004E21

In Vivo Flow Cytometry: A Horizon of Opportunities

Auteurs : Valery V. Tuchin [Russie] ; Attila Tárnok ; Vladimir P. Zharov [États-Unis]

Source :

Cytometry. Part A : the journal of the International Society for Analytical Cytology [ 1552-4922 ] ; 2011.

RBID : PMC:3663136

Abstract

Flow cytometry has been a fundamental tool of biological discovery for many years. Invasive extraction of cells from a living organism, however, may lead to changes in cell properties and prevents studying cells in their native environment. These problems can be overcome by use of in vivo flow cytometry which provides detection and imaging of circulating normal and abnormal cells directlyin blood or lymph flow. The goal of this mini-review is to provide a brief history, features and challenges of this new generation of flow cytometry methods and instruments. Spectrum of possibilities of in vivo flow cytometry in biological science (e.g., cell metabolism, immune function, or apoptosis) and medical fields (e.g., cancer, infection, cardiovascular disorder) including integrated photoacoustic-photothermal theranostics of circulating abnormal cells are discussed with focus on recent advances of this new platform.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663136

DOI: 10.1002/cyto.a.21143
PubMed: 21915991
PubMed Central: 3663136

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p id="P1">Flow cytometry has been a fundamental tool of biological discovery for many years. Invasive extraction of cells from a living organism, however, may lead to changes in cell properties and prevents studying cells in their native environment. These problems can be overcome by use of <italic>in vivo</italic>
 flow cytometry which provides detection and imaging of circulating normal and abnormal cells directlyin blood or lymph flow. The goal of this mini-review is to provide a brief history, features and challenges of this new generation of flow cytometry methods and instruments. Spectrum of possibilities of <italic>in vivo</italic>
 flow cytometry in biological science (e.g., cell metabolism, immune function, or apoptosis) and medical fields (e.g., cancer, infection, cardiovascular disorder) including integrated photoacoustic-photothermal theranostics of circulating abnormal cells are discussed with focus on recent advances of this new platform.</p>
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Serveur d'exploration sur le lymphœdème

In Vivo Flow Cytometry: A Horizon of Opportunities

In Vivo Flow Cytometry: A Horizon of Opportunities

Source :

Abstract

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