JankovicV1, Main, Exploration, bibRecordById, pubmed:25899316

Identification of novel variants in LRRK2 gene in patients with Parkinson's disease in Serbian population.

Identifieur interne : 000024 ( Main/Exploration ); précédent : 000023; suivant : 000025

Identification of novel variants in LRRK2 gene in patients with Parkinson's disease in Serbian population.

Auteurs : Milena. Jankovi [Serbie] ; Nikola. Kresojevi [Serbie] ; Valerija. Dobri [Serbie] ; Vladana. Markovi [Serbie] ; Igor. Petrovi [Serbie] ; Ivana. Novakovi [Serbie] ; Vladimir. Kosti [Serbie]

Source :

Journal of the neurological sciences ; 2015.

RBID : pubmed:25899316

Descripteurs français

Wicri :
- geographic : Serbie.

English descriptors

KwdEn :
- Adult, Aged, DNA Mutational Analysis, Exons, Female, Genetic Predisposition to Disease (genetics), Genotype, Humans, Male, Middle Aged, Parkinson Disease (epidemiology), Parkinson Disease (genetics), Polymorphism, Single Nucleotide (genetics), Protein-Serine-Threonine Kinases (genetics), Serbia (epidemiology), Young Adult.
MESH :
- chemical , genetics : Protein-Serine-Threonine Kinases.
- geographic , epidemiology : Serbia.
- epidemiology : Parkinson Disease.
- genetics : Genetic Predisposition to Disease, Parkinson Disease, Polymorphism, Single Nucleotide.
- Adult, Aged, DNA Mutational Analysis, Exons, Female, Genotype, Humans, Male, Middle Aged, Young Adult.

Abstract

Mutations in LRRK2 (leucine-rich repeat kinase 2) are the most common cause of autosomal dominant Parkinson's disease (PD). Large international studies have revealed that pathogenic mutations are clustered in several exons coding for functional domains of LRRK2 protein, but the mutation frequency differs among populations. Systematic study of LRRK2 mutation prevalence and phenotype in Serbian population has not been performed.

DOI: 10.1016/j.jns.2015.04.002
PubMed: 25899316

Affiliations:

Serbie

Le document en format XML

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<author><name sortKey="Jankovi, Milena Z" sort="Jankovi, Milena Z" uniqKey="Jankovi M" first="Milena" last="Jankovi">Milena. Jankovi</name>
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<author><name sortKey="Kresojevi, Nikola D" sort="Kresojevi, Nikola D" uniqKey="Kresojevi N" first="Nikola" last="Kresojevi">Nikola. Kresojevi</name>
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<country xml:lang="fr">Serbie</country>
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<author><name sortKey="Dobri I, Valerija S" sort="Dobri I, Valerija S" uniqKey="Dobri I V" first="Valerija" last="Dobri">Valerija. Dobri</name>
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<author><name sortKey="Markovi, Vladana V" sort="Markovi, Vladana V" uniqKey="Markovi V" first="Vladana" last="Markovi">Vladana. Markovi</name>
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<author><name sortKey="Novakovi, Ivana V" sort="Novakovi, Ivana V" uniqKey="Novakovi I" first="Ivana" last="Novakovi">Ivana. Novakovi</name>
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<author><name sortKey="Kosti, Vladimir S" sort="Kosti, Vladimir S" uniqKey="Kosti V" first="Vladimir" last="Kosti">Vladimir. Kosti</name>
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<front><div type="abstract" xml:lang="en">Mutations in LRRK2 (leucine-rich repeat kinase 2) are the most common cause of autosomal dominant Parkinson's disease (PD). Large international studies have revealed that pathogenic mutations are clustered in several exons coding for functional domains of LRRK2 protein, but the mutation frequency differs among populations. Systematic study of LRRK2 mutation prevalence and phenotype in Serbian population has not been performed.</div>
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<tree><country name="Serbie"><noRegion><name sortKey="Jankovi, Milena Z" sort="Jankovi, Milena Z" uniqKey="Jankovi M" first="Milena" last="Jankovi">Milena. Jankovi</name>
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Serveur d'exploration autour de Joseph Jankovic

Identification of novel variants in LRRK2 gene in patients with Parkinson's disease in Serbian population.

Identification of novel variants in LRRK2 gene in patients with Parkinson's disease in Serbian population.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration autour de Joseph Jankovic
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