Identification of novel variants in LRRK2 gene in patients with Parkinson's disease in Serbian population.
Identifieur interne : 000496 ( Ncbi/Merge ); précédent : 000495; suivant : 000497Identification of novel variants in LRRK2 gene in patients with Parkinson's disease in Serbian population.
Auteurs : Milena. Jankovi [Serbie] ; Nikola. Kresojevi [Serbie] ; Valerija. Dobri [Serbie] ; Vladana. Markovi [Serbie] ; Igor. Petrovi [Serbie] ; Ivana. Novakovi [Serbie] ; Vladimir. Kosti [Serbie]Source :
- Journal of the neurological sciences ; 2015.
Descripteurs français
- Wicri :
- geographic : Serbie.
English descriptors
- KwdEn :
- Adult, Aged, DNA Mutational Analysis, Exons, Female, Genetic Predisposition to Disease (genetics), Genotype, Humans, Male, Middle Aged, Parkinson Disease (epidemiology), Parkinson Disease (genetics), Polymorphism, Single Nucleotide (genetics), Protein-Serine-Threonine Kinases (genetics), Serbia (epidemiology), Young Adult.
- MESH :
- chemical , genetics : Protein-Serine-Threonine Kinases.
- geographic , epidemiology : Serbia.
- epidemiology : Parkinson Disease.
- genetics : Genetic Predisposition to Disease, Parkinson Disease, Polymorphism, Single Nucleotide.
- Adult, Aged, DNA Mutational Analysis, Exons, Female, Genotype, Humans, Male, Middle Aged, Young Adult.
Abstract
Mutations in LRRK2 (leucine-rich repeat kinase 2) are the most common cause of autosomal dominant Parkinson's disease (PD). Large international studies have revealed that pathogenic mutations are clustered in several exons coding for functional domains of LRRK2 protein, but the mutation frequency differs among populations. Systematic study of LRRK2 mutation prevalence and phenotype in Serbian population has not been performed.
DOI: 10.1016/j.jns.2015.04.002
PubMed: 25899316
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000013
- to stream PubMed, to step Curation: 000013
- to stream PubMed, to step Checkpoint: 000009
Links to Exploration step
pubmed:25899316Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Identification of novel variants in LRRK2 gene in patients with Parkinson's disease in Serbian population.</title><author><name sortKey="Jankovi, Milena Z" sort="Jankovi, Milena Z" uniqKey="Jankovi M" first="Milena" last="Jankovi">Milena. Jankovi</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="Kresojevi, Nikola D" sort="Kresojevi, Nikola D" uniqKey="Kresojevi N" first="Nikola" last="Kresojevi">Nikola. Kresojevi</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="Dobri I, Valerija S" sort="Dobri I, Valerija S" uniqKey="Dobri I V" first="Valerija" last="Dobri">Valerija. Dobri</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="Markovi, Vladana V" sort="Markovi, Vladana V" uniqKey="Markovi V" first="Vladana" last="Markovi">Vladana. Markovi</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="Petrovi, Igor N" sort="Petrovi, Igor N" uniqKey="Petrovi I" first="Igor" last="Petrovi">Igor. Petrovi</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="Novakovi, Ivana V" sort="Novakovi, Ivana V" uniqKey="Novakovi I" first="Ivana" last="Novakovi">Ivana. Novakovi</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Human Genetics, School of Medicine, University of Belgrade, Visegradska 26, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Institute for Human Genetics, School of Medicine, University of Belgrade, Visegradska 26, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="Kosti, Vladimir S" sort="Kosti, Vladimir S" uniqKey="Kosti V" first="Vladimir" last="Kosti">Vladimir. Kosti</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia. Electronic address: vladimir.s.kostic@gmail.com.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:25899316</idno><idno type="pmid">25899316</idno><idno type="doi">10.1016/j.jns.2015.04.002</idno><idno type="wicri:Area/PubMed/Corpus">000013</idno><idno type="wicri:Area/PubMed/Curation">000013</idno><idno type="wicri:Area/PubMed/Checkpoint">000009</idno><idno type="wicri:Area/Ncbi/Merge">000496</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Identification of novel variants in LRRK2 gene in patients with Parkinson's disease in Serbian population.</title><author><name sortKey="Jankovi, Milena Z" sort="Jankovi, Milena Z" uniqKey="Jankovi M" first="Milena" last="Jankovi">Milena. Jankovi</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="Kresojevi, Nikola D" sort="Kresojevi, Nikola D" uniqKey="Kresojevi N" first="Nikola" last="Kresojevi">Nikola. Kresojevi</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="Dobri I, Valerija S" sort="Dobri I, Valerija S" uniqKey="Dobri I V" first="Valerija" last="Dobri">Valerija. Dobri</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="Markovi, Vladana V" sort="Markovi, Vladana V" uniqKey="Markovi V" first="Vladana" last="Markovi">Vladana. Markovi</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="Petrovi, Igor N" sort="Petrovi, Igor N" uniqKey="Petrovi I" first="Igor" last="Petrovi">Igor. Petrovi</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="Novakovi, Ivana V" sort="Novakovi, Ivana V" uniqKey="Novakovi I" first="Ivana" last="Novakovi">Ivana. Novakovi</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Human Genetics, School of Medicine, University of Belgrade, Visegradska 26, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Institute for Human Genetics, School of Medicine, University of Belgrade, Visegradska 26, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="Kosti, Vladimir S" sort="Kosti, Vladimir S" uniqKey="Kosti V" first="Vladimir" last="Kosti">Vladimir. Kosti</name><affiliation wicri:level="1"><nlm:affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia. Electronic address: vladimir.s.kostic@gmail.com.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of the neurological sciences</title><idno type="e-ISSN">1878-5883</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>DNA Mutational Analysis</term><term>Exons</term><term>Female</term><term>Genetic Predisposition to Disease (genetics)</term><term>Genotype</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (epidemiology)</term><term>Parkinson Disease (genetics)</term><term>Polymorphism, Single Nucleotide (genetics)</term><term>Protein-Serine-Threonine Kinases (genetics)</term><term>Serbia (epidemiology)</term><term>Young Adult</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Protein-Serine-Threonine Kinases</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Serbia</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Genetic Predisposition to Disease</term><term>Parkinson Disease</term><term>Polymorphism, Single Nucleotide</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>DNA Mutational Analysis</term><term>Exons</term><term>Female</term><term>Genotype</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Young Adult</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Serbie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Mutations in LRRK2 (leucine-rich repeat kinase 2) are the most common cause of autosomal dominant Parkinson's disease (PD). Large international studies have revealed that pathogenic mutations are clustered in several exons coding for functional domains of LRRK2 protein, but the mutation frequency differs among populations. Systematic study of LRRK2 mutation prevalence and phenotype in Serbian population has not been performed.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">25899316</PMID><DateCreated><Year>2015</Year><Month>05</Month><Day>18</Day></DateCreated><DateCompleted><Year>2016</Year><Month>01</Month><Day>29</Day></DateCompleted><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1878-5883</ISSN><JournalIssue CitedMedium="Internet"><Volume>353</Volume><Issue>1-2</Issue><PubDate><Year>2015</Year></PubDate></JournalIssue><Title>Journal of the neurological sciences</Title><ISOAbbreviation>J. Neurol. Sci.</ISOAbbreviation></Journal><ArticleTitle>Identification of novel variants in LRRK2 gene in patients with Parkinson's disease in Serbian population.</ArticleTitle><Pagination><MedlinePgn>59-62</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jns.2015.04.002</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0022-510X(15)00199-9</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Mutations in LRRK2 (leucine-rich repeat kinase 2) are the most common cause of autosomal dominant Parkinson's disease (PD). Large international studies have revealed that pathogenic mutations are clustered in several exons coding for functional domains of LRRK2 protein, but the mutation frequency differs among populations. Systematic study of LRRK2 mutation prevalence and phenotype in Serbian population has not been performed.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Comprehensive mutation screening of selected exons of LRRK2 was performed in 486 Serbian PD patients.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Previously reported mutations I1371V and G2019S were identified in a single patient each, and c.4536+3A>G substitution in two patients. G2019S is the most common, pathogenic mutation, while pathogenic roles for recurrent variants I1371V and c.4536+3A>G are not confirmed yet. Two novel variants S1508G and I1991V were discovered in 2 unrelated patients. These variants are considered as disease causing according to several software predictions, but additional segregation and functional analyses are required.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Mutation frequency in our study (1.23%) was similar to other European populations, although the most common mutations were underestimated and novel variants were detected. In most cases, symptoms of LRRK2-PD are similar to sporadic PD, so estimation of frequency and penetrance of mutations in different populations is important for efficient genetic testing strategy and counseling.</AbstractText><CopyrightInformation>Copyright © 2015 Elsevier B.V. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Janković</LastName><ForeName>Milena Z</ForeName><Initials>MZ</Initials><AffiliationInfo><Affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kresojević</LastName><ForeName>Nikola D</ForeName><Initials>ND</Initials><AffiliationInfo><Affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dobričić</LastName><ForeName>Valerija S</ForeName><Initials>VS</Initials><AffiliationInfo><Affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marković</LastName><ForeName>Vladana V</ForeName><Initials>VV</Initials><AffiliationInfo><Affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Petrović</LastName><ForeName>Igor N</ForeName><Initials>IN</Initials><AffiliationInfo><Affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Novaković</LastName><ForeName>Ivana V</ForeName><Initials>IV</Initials><AffiliationInfo><Affiliation>Institute for Human Genetics, School of Medicine, University of Belgrade, Visegradska 26, Belgrade, Serbia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kostić</LastName><ForeName>Vladimir S</ForeName><Initials>VS</Initials><AffiliationInfo><Affiliation>Neurology Clinic, School of Medicine, University of Belgrade, Dr. Subotica 6, Belgrade, Serbia. Electronic address: vladimir.s.kostic@gmail.com.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>04</Month><Day>12</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>J Neurol Sci</MedlineTA><NlmUniqueID>0375403</NlmUniqueID><ISSNLinking>0022-510X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>EC 2.7.11.1</RegistryNumber><NameOfSubstance UI="C495280">LRRK2 protein, human</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 2.7.11.1</RegistryNumber><NameOfSubstance UI="D017346">Protein-Serine-Threonine Kinases</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004252">DNA Mutational Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005091">Exons</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D020022">Genetic Predisposition to Disease</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000235">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005838">Genotype</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000453">epidemiology</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000235">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D020641">Polymorphism, Single Nucleotide</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000235">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D017346">Protein-Serine-Threonine Kinases</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000235">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" Type="Geographic" UI="D055771">Serbia</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000453">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D055815">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Genetics</Keyword><Keyword MajorTopicYN="N">LRRK2</Keyword><Keyword MajorTopicYN="N">Late onset</Keyword><Keyword MajorTopicYN="N">Mutation</Keyword><Keyword MajorTopicYN="N">PARK8</Keyword><Keyword MajorTopicYN="N">Parkinson's disease</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year><Month>12</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2015</Year><Month>3</Month><Day>10</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>4</Month><Day>2</Day></PubMedPubDate><PubMedPubDate PubStatus="aheadofprint"><Year>2015</Year><Month>4</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>4</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>4</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>1</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">25899316</ArticleId><ArticleId IdType="pii">S0022-510X(15)00199-9</ArticleId><ArticleId IdType="doi">10.1016/j.jns.2015.04.002</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Serbie</li></country></list><tree><country name="Serbie"><noRegion><name sortKey="Jankovi, Milena Z" sort="Jankovi, Milena Z" uniqKey="Jankovi M" first="Milena" last="Jankovi">Milena. Jankovi</name></noRegion><name sortKey="Dobri I, Valerija S" sort="Dobri I, Valerija S" uniqKey="Dobri I V" first="Valerija" last="Dobri">Valerija. Dobri</name><name sortKey="Kosti, Vladimir S" sort="Kosti, Vladimir S" uniqKey="Kosti V" first="Vladimir" last="Kosti">Vladimir. Kosti</name><name sortKey="Kresojevi, Nikola D" sort="Kresojevi, Nikola D" uniqKey="Kresojevi N" first="Nikola" last="Kresojevi">Nikola. Kresojevi</name><name sortKey="Markovi, Vladana V" sort="Markovi, Vladana V" uniqKey="Markovi V" first="Vladana" last="Markovi">Vladana. Markovi</name><name sortKey="Novakovi, Ivana V" sort="Novakovi, Ivana V" uniqKey="Novakovi I" first="Ivana" last="Novakovi">Ivana. Novakovi</name><name sortKey="Petrovi, Igor N" sort="Petrovi, Igor N" uniqKey="Petrovi I" first="Igor" last="Petrovi">Igor. Petrovi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/JankovicV1/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000496 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 000496 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= JankovicV1
|flux= Ncbi
|étape= Merge
|type= RBID
|clé= pubmed:25899316
|texte= Identification of novel variants in LRRK2 gene in patients with Parkinson's disease in Serbian population.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:25899316" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a JankovicV1
| This area was generated with Dilib version V0.6.19. |  |