Serveur d'exploration autour de Joseph Jankovic

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Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

Identifieur interne : 001917 ( Main/Exploration ); précédent : 001916; suivant : 001918

Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

Auteurs : E Lai [États-Unis] ; J Jankovic [États-Unis] ; J Krauss [États-Unis] ; W Ondo [États-Unis] ; R Grossman [États-Unis]

Source :

RBID : Pascal:00-0521167

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English descriptors

Abstract

The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale "off" state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both "off" and "on" states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).


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Le document en format XML

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<div type="abstract" xml:lang="en">The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale "off" state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both "off" and "on" states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).</div>
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