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Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

Identifieur interne : 000011 ( PascalFrancis/Curation ); précédent : 000010; suivant : 000012

Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

Auteurs : E Lai [États-Unis] ; J Jankovic [États-Unis] ; J Krauss [États-Unis] ; W Ondo [États-Unis] ; R Grossman [États-Unis]

Source :

RBID : Pascal:00-0521167

Descripteurs français

English descriptors

Abstract

The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale "off" state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both "off" and "on" states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).
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A11 04  1    @1 ONDO (W. G.)
A11 05  1    @1 GROSSMAN (R. G.)
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C01 01    ENG  @0 The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale "off" state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both "off" and "on" states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).
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C03 02  X  FRE  @0 Pallidum @5 04
C03 02  X  ENG  @0 Pallidum @5 04
C03 02  X  SPA  @0 Pallidum @5 04
C03 03  X  FRE  @0 Section chirurgicale @5 07
C03 03  X  ENG  @0 Surgical section @5 07
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C07 04  X  SPA  @0 Extrapiramidal síndrome @5 40
C07 05  X  FRE  @0 Maladie dégénérative @5 41
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C07 05  X  SPA  @0 Enfermedad degenerativa @5 41
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C07 06  X  ENG  @0 Brain (vertebrata) @5 45
C07 06  X  SPA  @0 Encéfalo @5 45
C07 07  X  FRE  @0 Chirurgie @5 53
C07 07  X  ENG  @0 Surgery @5 53
C07 07  X  SPA  @0 Cirugía @5 53
N21       @1 346

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Pascal:00-0521167

Le document en format XML

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<s0>Cirugía</s0>
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