JankovicV1, Main, Curation, bibRecord, 001917

Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

Identifieur interne : 001917 ( Main/Curation ); précédent : 001916; suivant : 001918

Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

Auteurs : E Lai [États-Unis] ; J Jankovic [États-Unis] ; J Krauss [États-Unis] ; W Ondo [États-Unis] ; R Grossman [États-Unis]

Source :

Neurology [ 0028-3878 ] ; 2000.

RBID : Pascal:00-0521167

Descripteurs français

Pascal (Inist)
- Parkinson maladie, Pallidum, Section chirurgicale, Long terme, Efficacité traitement, Homme.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Adult, Aged, Female, Follow-Up Studies, Functional Laterality (physiology), Globus Pallidus (surgery), Human, Humans, Long term, Male, Middle Aged, Pallidum, Parkinson Disease (surgery), Parkinson disease, Surgical section, Time Factors, Treatment efficiency.
MESH :
- physiology : Functional Laterality.
- surgery : Globus Pallidus, Parkinson Disease.
- Adult, Aged, Female, Follow-Up Studies, Humans, Male, Middle Aged, Time Factors.

Abstract

The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale "off" state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both "off" and "on" states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).

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Le document en format XML

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<front><div type="abstract" xml:lang="en">The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale "off" state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both "off" and "on" states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).</div>
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<front><div type="abstract" xml:lang="en">The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale "off" state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both "off" and "on" states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).</div>
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<author><name sortKey="Jankovic, J" sort="Jankovic, J" uniqKey="Jankovic J" first="J" last="Jankovic">Joseph Jankovic</name>
<affiliation><country>États-Unis</country>
<placeName><settlement type="city">Houston</settlement>
<region type="state">Texas</region>
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<orgName type="university" n="3">Baylor College of Medicine</orgName>
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<author><name sortKey="Ondo, W G" sort="Ondo, W G" uniqKey="Ondo W" first="W" last="Ondo">W Ondo</name>
</author>
<author><name sortKey="Grossman, R G" sort="Grossman, R G" uniqKey="Grossman R" first="R" last="Grossman">R Grossman</name>
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<date when="2000">2000</date>
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<idno type="wicri:doubleKey">0028-3878:2000:Lai E:long:term:efficacy</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease.</title>
<author><name sortKey="Lai, E C" sort="Lai, E C" uniqKey="Lai E" first="E" last="Lai">E Lai</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, Baylor College of Medicine, The Methodist Hospital, Houston Veterans Affairs Medical Center, TX 77030, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Baylor College of Medicine, The Methodist Hospital, Houston Veterans Affairs Medical Center, TX 77030</wicri:regionArea>
<placeName><region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jankovic, J" sort="Jankovic, J" uniqKey="Jankovic J" first="J" last="Jankovic">Joseph Jankovic</name>
<affiliation><country>États-Unis</country>
<placeName><settlement type="city">Houston</settlement>
<region type="state">Texas</region>
</placeName>
<orgName type="university" n="3">Baylor College of Medicine</orgName>
</affiliation>
</author>
<author><name sortKey="Krauss, J K" sort="Krauss, J K" uniqKey="Krauss J" first="J" last="Krauss">J Krauss</name>
</author>
<author><name sortKey="Ondo, W G" sort="Ondo, W G" uniqKey="Ondo W" first="W" last="Ondo">W Ondo</name>
</author>
<author><name sortKey="Grossman, R G" sort="Grossman, R G" uniqKey="Grossman R" first="R" last="Grossman">R Grossman</name>
</author>
</analytic>
<series><title level="j">Neurology</title>
<idno type="ISSN">0028-3878</idno>
<imprint><date when="2000" type="published">2000</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Functional Laterality (physiology)</term>
<term>Globus Pallidus (surgery)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (surgery)</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Functional Laterality</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Globus Pallidus</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Time Factors</term>
</keywords>
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<front><div type="abstract" xml:lang="en">The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale "off" state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p <0.001). Improvements in parkinsonian symptoms were maintained in both"off" and "on" states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).</div>
</front>
</TEI>
</PubMed>
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Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

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