Re-understanding anti-influenza strategy: attach equal importance to antiviral and anti-inflammatory therapies
Identifieur interne : 000C90 ( Pmc/Curation ); précédent : 000C89; suivant : 000C91Re-understanding anti-influenza strategy: attach equal importance to antiviral and anti-inflammatory therapies
Auteurs : Zhengtu Li [République populaire de Chine] ; Li Li ; Shuai Zhao [République populaire de Chine] ; Jing Li [République populaire de Chine] ; Hongxia Zhou [République populaire de Chine] ; Yunhui Zhang [République populaire de Chine] ; Zifeng Yang [République populaire de Chine] ; Bing Yuan [République populaire de Chine]Source :
- Journal of Thoracic Disease [ 2072-1439 ] ; 2018.
Abstract
The direct replication of influenza virus is not the only cause of harm to human health; influenza infection leading to a hyper-inflammatory immune response can also result in serious conditions. So, the treatment strategy for influenza needs to keep balance between antivirus and anti-inflammation. Herein, we review the treatment strategies of anti-influenza drugs and traditional Chinese medicines.
Url:
DOI: 10.21037/jtd.2018.03.169
PubMed: 30116604
PubMed Central: 6072919
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Hospital of Yulin, Yulin<addr-line>719000,<country>China</country></addr-line>;</nlm:aff></affiliation></author><author><name sortKey="Zhao, Shuai" sort="Zhao, Shuai" uniqKey="Zhao S" first="Shuai" last="Zhao">Shuai Zhao</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Emergency,<institution>The Second Clinical College of Guangzhou University of Chinese Medicine</institution>,<addr-line>Guangzhou 510120</addr-line>,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Li, Jing" sort="Li, Jing" uniqKey="Li J" first="Jing" last="Li">Jing Li</name><affiliation wicri:level="1"><nlm:aff id="aff1">State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University,<institution>(Guangzhou Medical University)</institution>,<addr-line>Guangzhou 510120</addr-line>,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zhou, Hongxia" sort="Zhou, Hongxia" uniqKey="Zhou H" first="Hongxia" last="Zhou">Hongxia Zhou</name><affiliation wicri:level="1"><nlm:aff id="aff1">State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University,<institution>(Guangzhou Medical University)</institution>,<addr-line>Guangzhou 510120</addr-line>,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Yunhui" sort="Zhang, Yunhui" uniqKey="Zhang Y" 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see nlm:aff country strict</wicri:regionArea></affiliation><affiliation><nlm:aff id="aff5">Department of Faculty of Chinese Medicine, Macau University of Science and Technology, Macau<addr-line>519020,<country>China</country></addr-line></nlm:aff></affiliation></author><author><name sortKey="Yuan, Bing" sort="Yuan, Bing" uniqKey="Yuan B" first="Bing" last="Yuan">Bing Yuan</name><affiliation wicri:level="1"><nlm:aff id="aff1">State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University,<institution>(Guangzhou Medical University)</institution>,<addr-line>Guangzhou 510120</addr-line>,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff4">Department of Respiration,<institution>First 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strategy: attach equal importance to antiviral and anti-inflammatory therapies</title><author><name sortKey="Li, Zhengtu" sort="Li, Zhengtu" uniqKey="Li Z" first="Zhengtu" last="Li">Zhengtu Li</name><affiliation wicri:level="1"><nlm:aff id="aff1">State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University,<institution>(Guangzhou Medical University)</institution>,<addr-line>Guangzhou 510120</addr-line>,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Li, Li" sort="Li, Li" uniqKey="Li L" first="Li" last="Li">Li Li</name><affiliation><nlm:aff id="aff2">Department of Respiration, The First Hospital of Yulin, Yulin<addr-line>719000,<country>China</country></addr-line>;</nlm:aff></affiliation></author><author><name sortKey="Zhao, Shuai" sort="Zhao, Shuai" uniqKey="Zhao S" first="Shuai" last="Zhao">Shuai Zhao</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Emergency,<institution>The Second Clinical College of Guangzhou University of Chinese Medicine</institution>,<addr-line>Guangzhou 510120</addr-line>,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Li, Jing" sort="Li, Jing" uniqKey="Li J" first="Jing" last="Li">Jing Li</name><affiliation wicri:level="1"><nlm:aff id="aff1">State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University,<institution>(Guangzhou Medical University)</institution>,<addr-line>Guangzhou 510120</addr-line>,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zhou, Hongxia" sort="Zhou, Hongxia" uniqKey="Zhou H" first="Hongxia" last="Zhou">Hongxia Zhou</name><affiliation wicri:level="1"><nlm:aff id="aff1">State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University,<institution>(Guangzhou Medical University)</institution>,<addr-line>Guangzhou 510120</addr-line>,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Yunhui" sort="Zhang, Yunhui" uniqKey="Zhang Y" first="Yunhui" last="Zhang">Yunhui Zhang</name><affiliation wicri:level="1"><nlm:aff id="aff4">Department of Respiration,<institution>First People’s Hospital of Yunnan Province</institution>,<addr-line>Yunnan 650032</addr-line>,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Yang, Zifeng" sort="Yang, Zifeng" uniqKey="Yang Z" first="Zifeng" last="Yang">Zifeng Yang</name><affiliation wicri:level="1"><nlm:aff id="aff1">State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University,<institution>(Guangzhou Medical University)</institution>,<addr-line>Guangzhou 510120</addr-line>,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation><nlm:aff id="aff5">Department of Faculty of Chinese Medicine, Macau University of Science and Technology, Macau<addr-line>519020,<country>China</country></addr-line></nlm:aff></affiliation></author><author><name sortKey="Yuan, Bing" sort="Yuan, Bing" uniqKey="Yuan B" first="Bing" last="Yuan">Bing Yuan</name><affiliation wicri:level="1"><nlm:aff id="aff1">State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University,<institution>(Guangzhou Medical University)</institution>,<addr-line>Guangzhou 510120</addr-line>,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff4">Department of Respiration,<institution>First People’s Hospital of Yunnan Province</institution>,<addr-line>Yunnan 650032</addr-line>,<country>China</country>;</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Journal of Thoracic Disease</title><idno type="ISSN">2072-1439</idno><idno type="eISSN">2077-6624</idno><imprint><date when="2018">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The direct replication of influenza virus is not the only cause of harm to human health; influenza infection leading to a hyper-inflammatory immune response can also result in serious conditions. So, the treatment strategy for influenza needs to keep balance between antivirus and anti-inflammation. Herein, we review the treatment strategies of anti-influenza drugs and traditional Chinese medicines.</p></div></front></TEI><pmc article-type="review-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Thorac Dis</journal-id><journal-id journal-id-type="iso-abbrev">J Thorac Dis</journal-id><journal-id journal-id-type="publisher-id">JTD</journal-id><journal-title-group><journal-title>Journal of Thoracic Disease</journal-title></journal-title-group><issn pub-type="ppub">2072-1439</issn><issn pub-type="epub">2077-6624</issn><publisher><publisher-name>AME Publishing Company</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">30116604</article-id><article-id pub-id-type="pmc">6072919</article-id><article-id pub-id-type="publisher-id">jtd-10-S19-S2248</article-id><article-id pub-id-type="doi">10.21037/jtd.2018.03.169</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title>Re-understanding anti-influenza strategy: attach equal importance to antiviral and anti-inflammatory therapies</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Li</surname><given-names>Zhengtu</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="author-notes" rid="afn2"><sup>#</sup></xref></contrib><contrib contrib-type="author"><name><surname>Li</surname><given-names>Li</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="author-notes" rid="afn2"><sup>#</sup></xref></contrib><contrib contrib-type="author"><name><surname>Zhao</surname><given-names>Shuai</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref><xref ref-type="author-notes" rid="afn2"><sup>#</sup></xref></contrib><contrib contrib-type="author"><name><surname>Li</surname><given-names>Jing</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Zhou</surname><given-names>Hongxia</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Zhang</surname><given-names>Yunhui</given-names></name><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Yang</surname><given-names>Zifeng</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff5"><sup>5</sup></xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Yuan</surname><given-names>Bing</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib><aff id="aff1"><label>1</label>State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University,<institution>(Guangzhou Medical University)</institution>,<addr-line>Guangzhou 510120</addr-line>,<country>China</country>;</aff><aff id="aff2"><label>2</label>Department of Respiration, The First Hospital of Yulin, Yulin<addr-line>719000,<country>China</country></addr-line>;</aff><aff id="aff3"><label>3</label>Department of Emergency,<institution>The Second Clinical College of Guangzhou University of Chinese Medicine</institution>,<addr-line>Guangzhou 510120</addr-line>,<country>China</country>;</aff><aff id="aff4"><label>4</label>Department of Respiration,<institution>First People’s Hospital of Yunnan Province</institution>,<addr-line>Yunnan 650032</addr-line>,<country>China</country>;</aff><aff id="aff5"><label>5</label>Department of Faculty of Chinese Medicine, Macau University of Science and Technology, Macau<addr-line>519020,<country>China</country></addr-line></aff></contrib-group><author-notes><fn id="afn1"><p><italic>Contributions:</italic> (I) Conception and design: Z Li, Y Zhang, B Yuan, Z Yang; (II) Administrative support: L Li, S Zhao, H Zhou, J Li, B Yuan; (III) Provision of study materials or patients: L Li, S Zhao; (IV) Collection and assembly of data: H Zhou, J Li; (V) Data analysis and interpretation: Z Li, L Li, S Zhao, B Yuan; (VI) Manuscript writing: All authors; (VII) Final approval of the manuscript: All authors.</p></fn><fn id="afn2" fn-type="equal"><label>#</label><p>These authors contributed equally to this work.</p></fn><corresp id="cor1"><italic>Correspondence to:</italic> Zifeng Yang. State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Hospital of Guangzhou Medical University, No. 151, Rd. Yanjiang, Guangzhou 510000, China. Email: <email xlink:href="jeffyah@163.com">jeffyah@163.com</email>; Bing Yuan. Department of Respiration, First People’s Hospital of Yunnan Province, No. 157, Jinbi Road, Kunming 50032, China. Email: <email xlink:href="506638016@qq.com">506638016@qq.com</email>.</corresp><fn fn-type="COI-statement"><p><italic>Conflicts of Interest:</italic> The authors have no conflicts of interest to declare.</p></fn></author-notes><pub-date pub-type="epub-ppub"><month>7</month><year>2018</year></pub-date><pmc-comment>Fake ppub date generated by PMC from publisher
pub-date/@pub-type='epub-ppub' </pmc-comment>
<pub-date pub-type="ppub"><month>7</month><year>2018</year></pub-date><volume>10</volume><issue>Suppl 19</issue><fpage>S2248</fpage><lpage>S2259</lpage><history><date date-type="received"><day>12</day><month>7</month><year>2017</year></date><date date-type="accepted"><day>21</day><month>12</month><year>2017</year></date></history><permissions><copyright-statement>2018 Journal of Thoracic Disease. All rights reserved.</copyright-statement><copyright-year>2018</copyright-year><copyright-holder>Journal of Thoracic Disease.</copyright-holder></permissions><abstract><p>The direct replication of influenza virus is not the only cause of harm to human health; influenza infection leading to a hyper-inflammatory immune response can also result in serious conditions. So, the treatment strategy for influenza needs to keep balance between antivirus and anti-inflammation. Herein, we review the treatment strategies of anti-influenza drugs and traditional Chinese medicines.</p></abstract><kwd-group kwd-group-type="author"><title>Keywords: </title><kwd>Influenza</kwd><kwd>antivirus</kwd><kwd>anti-inflammation</kwd><kwd>chemical drug</kwd><kwd>traditional Chinese medicine</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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