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Re-understanding anti-influenza strategy: attach equal importance to antiviral and anti-inflammatory therapies

Identifieur interne : 000C90 ( Pmc/Corpus ); précédent : 000C89; suivant : 000C91

Re-understanding anti-influenza strategy: attach equal importance to antiviral and anti-inflammatory therapies

Auteurs : Zhengtu Li ; Li Li ; Shuai Zhao ; Jing Li ; Hongxia Zhou ; Yunhui Zhang ; Zifeng Yang ; Bing Yuan

Source :

RBID : PMC:6072919

Abstract

The direct replication of influenza virus is not the only cause of harm to human health; influenza infection leading to a hyper-inflammatory immune response can also result in serious conditions. So, the treatment strategy for influenza needs to keep balance between antivirus and anti-inflammation. Herein, we review the treatment strategies of anti-influenza drugs and traditional Chinese medicines.


Url:
DOI: 10.21037/jtd.2018.03.169
PubMed: 30116604
PubMed Central: 6072919

Links to Exploration step

PMC:6072919

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<div type="abstract" xml:lang="en">
<p>The direct replication of influenza virus is not the only cause of harm to human health; influenza infection leading to a hyper-inflammatory immune response can also result in serious conditions. So, the treatment strategy for influenza needs to keep balance between antivirus and anti-inflammation. Herein, we review the treatment strategies of anti-influenza drugs and traditional Chinese medicines.</p>
</div>
</front>
</TEI>
<pmc article-type="review-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
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<journal-id journal-id-type="nlm-ta">J Thorac Dis</journal-id>
<journal-id journal-id-type="iso-abbrev">J Thorac Dis</journal-id>
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<journal-title-group>
<journal-title>Journal of Thoracic Disease</journal-title>
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<issn pub-type="ppub">2072-1439</issn>
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<article-id pub-id-type="pmid">30116604</article-id>
<article-id pub-id-type="pmc">6072919</article-id>
<article-id pub-id-type="publisher-id">jtd-10-S19-S2248</article-id>
<article-id pub-id-type="doi">10.21037/jtd.2018.03.169</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Review Article</subject>
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<title-group>
<article-title>Re-understanding anti-influenza strategy: attach equal importance to antiviral and anti-inflammatory therapies</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Li</surname>
<given-names>Zhengtu</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="author-notes" rid="afn2">
<sup>#</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Li</surname>
<given-names>Li</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<xref ref-type="author-notes" rid="afn2">
<sup>#</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Zhao</surname>
<given-names>Shuai</given-names>
</name>
<xref ref-type="aff" rid="aff3">
<sup>3</sup>
</xref>
<xref ref-type="author-notes" rid="afn2">
<sup>#</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Li</surname>
<given-names>Jing</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
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<contrib contrib-type="author">
<name>
<surname>Zhou</surname>
<given-names>Hongxia</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
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<name>
<surname>Zhang</surname>
<given-names>Yunhui</given-names>
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<sup>4</sup>
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<surname>Yang</surname>
<given-names>Zifeng</given-names>
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<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff5">
<sup>5</sup>
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<given-names>Bing</given-names>
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<aff id="aff1">
<label>1</label>
State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University,
<institution>(Guangzhou Medical University)</institution>
,
<addr-line>Guangzhou 510120</addr-line>
,
<country>China</country>
;</aff>
<aff id="aff2">
<label>2</label>
Department of Respiration, The First Hospital of Yulin, Yulin
<addr-line>719000,
<country>China</country>
</addr-line>
;</aff>
<aff id="aff3">
<label>3</label>
Department of Emergency,
<institution>The Second Clinical College of Guangzhou University of Chinese Medicine</institution>
,
<addr-line>Guangzhou 510120</addr-line>
,
<country>China</country>
;</aff>
<aff id="aff4">
<label>4</label>
Department of Respiration,
<institution>First People’s Hospital of Yunnan Province</institution>
,
<addr-line>Yunnan 650032</addr-line>
,
<country>China</country>
;</aff>
<aff id="aff5">
<label>5</label>
Department of Faculty of Chinese Medicine, Macau University of Science and Technology, Macau
<addr-line>519020,
<country>China</country>
</addr-line>
</aff>
</contrib-group>
<author-notes>
<fn id="afn1">
<p>
<italic>Contributions:</italic>
(I) Conception and design: Z Li, Y Zhang, B Yuan, Z Yang; (II) Administrative support: L Li, S Zhao, H Zhou, J Li, B Yuan; (III) Provision of study materials or patients: L Li, S Zhao; (IV) Collection and assembly of data: H Zhou, J Li; (V) Data analysis and interpretation: Z Li, L Li, S Zhao, B Yuan; (VI) Manuscript writing: All authors; (VII) Final approval of the manuscript: All authors.</p>
</fn>
<fn id="afn2" fn-type="equal">
<label>#</label>
<p>These authors contributed equally to this work.</p>
</fn>
<corresp id="cor1">
<italic>Correspondence to:</italic>
Zifeng Yang. State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Hospital of Guangzhou Medical University, No. 151, Rd. Yanjiang, Guangzhou 510000, China. Email:
<email xlink:href="jeffyah@163.com">jeffyah@163.com</email>
; Bing Yuan. Department of Respiration, First People’s Hospital of Yunnan Province, No. 157, Jinbi Road, Kunming 50032, China. Email:
<email xlink:href="506638016@qq.com">506638016@qq.com</email>
.</corresp>
<fn fn-type="COI-statement">
<p>
<italic>Conflicts of Interest:</italic>
The authors have no conflicts of interest to declare.</p>
</fn>
</author-notes>
<pub-date pub-type="epub-ppub">
<month>7</month>
<year>2018</year>
</pub-date>
<pmc-comment>Fake ppub date generated by PMC from publisher pub-date/@pub-type='epub-ppub' </pmc-comment>
<pub-date pub-type="ppub">
<month>7</month>
<year>2018</year>
</pub-date>
<volume>10</volume>
<issue>Suppl 19</issue>
<fpage>S2248</fpage>
<lpage>S2259</lpage>
<history>
<date date-type="received">
<day>12</day>
<month>7</month>
<year>2017</year>
</date>
<date date-type="accepted">
<day>21</day>
<month>12</month>
<year>2017</year>
</date>
</history>
<permissions>
<copyright-statement>2018 Journal of Thoracic Disease. All rights reserved.</copyright-statement>
<copyright-year>2018</copyright-year>
<copyright-holder>Journal of Thoracic Disease.</copyright-holder>
</permissions>
<abstract>
<p>The direct replication of influenza virus is not the only cause of harm to human health; influenza infection leading to a hyper-inflammatory immune response can also result in serious conditions. So, the treatment strategy for influenza needs to keep balance between antivirus and anti-inflammation. Herein, we review the treatment strategies of anti-influenza drugs and traditional Chinese medicines.</p>
</abstract>
<kwd-group kwd-group-type="author">
<title>Keywords: </title>
<kwd>Influenza</kwd>
<kwd>antivirus</kwd>
<kwd>anti-inflammation</kwd>
<kwd>chemical drug</kwd>
<kwd>traditional Chinese medicine</kwd>
</kwd-group>
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</front>
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