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Cyclosporin-A inhibits the expression of cyclooxygenase-2 in gingiva.

Identifieur interne : 006862 ( Main/Merge ); précédent : 006861; suivant : 006863

Cyclosporin-A inhibits the expression of cyclooxygenase-2 in gingiva.

Auteurs : C-Y Chiang [République populaire de Chine] ; Y-T Chen ; F-M Hung ; H-P Tu ; M M-J Fu ; E. Fu

Source :

RBID : pubmed:17760822

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English descriptors

Abstract

Various inflammatory mediators are involved in the development of cyclosporine A-induced gingival overgrowth. In this study, the gingival expression of cyclooxygenase-2 after cyclosporine A therapy was examined in vivo and in vitro.

DOI: 10.1111/j.1600-0765.2006.00967.x
PubMed: 17760822

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pubmed:17760822

Le document en format XML

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<nlm:affiliation>Department of Periodontology, School of Dentistry, National Defense Medical Center and Tri-Service General Hospital, Taipei, Taiwan, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Periodontology, School of Dentistry, National Defense Medical Center and Tri-Service General Hospital, Taipei, Taiwan</wicri:regionArea>
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<name sortKey="Chen, Y T" sort="Chen, Y T" uniqKey="Chen Y" first="Y-T" last="Chen">Y-T Chen</name>
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<name sortKey="Hung, F M" sort="Hung, F M" uniqKey="Hung F" first="F-M" last="Hung">F-M Hung</name>
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<term>Cyclooxygenase 2 (analysis)</term>
<term>Cyclooxygenase 2 Inhibitors (pharmacology)</term>
<term>Cyclosporine (pharmacology)</term>
<term>Dinoprostone (analysis)</term>
<term>Enzyme Inhibitors (pharmacology)</term>
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<term>Fibroblasts (enzymology)</term>
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<term>Gingiva (enzymology)</term>
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<term>Rats, Sprague-Dawley</term>
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<div type="abstract" xml:lang="en">Various inflammatory mediators are involved in the development of cyclosporine A-induced gingival overgrowth. In this study, the gingival expression of cyclooxygenase-2 after cyclosporine A therapy was examined in vivo and in vitro.</div>
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