Biocompatibility and manageability of a new fixable bone graft for the treatment of localized bone defects: preliminary study in a dog model.
Identifieur interne : 006083 ( Main/Exploration ); précédent : 006082; suivant : 006084Biocompatibility and manageability of a new fixable bone graft for the treatment of localized bone defects: preliminary study in a dog model.
Auteurs : Filippo Fontana [Italie] ; Isabella Rocchietta ; Claudia Dellavia ; Myron Nevins ; Massimo SimionSource :
- The International journal of periodontics & restorative dentistry [ 0198-7569 ] ; 2008.
Descripteurs français
- KwdFr :
- Animaux, Attribution aléatoire, Bovins, Chiens, Collagène (usage thérapeutique), Durapatite (usage thérapeutique), Equus caballus, Facteurs temps, Fixateurs internes, Lâchage de suture (étiologie), Mandibule (), Mandibule (anatomopathologie), Matériaux biocompatibles (usage thérapeutique), Minéraux (usage thérapeutique), Modèles animaux, Mâchoire partiellement édentée (), Mâchoire partiellement édentée (anatomopathologie), Mâle, Prémolaire, Reconstruction de crête alvéolaire (), Reconstruction de crête alvéolaire (instrumentation), Remodelage osseux (physiologie), Substituts osseux (usage thérapeutique), Sécurité, Trame osseuse (transplantation), Vis orthopédiques.
- MESH :
- anatomopathologie : Mandibule, Mâchoire partiellement édentée.
- physiologie : Remodelage osseux.
- usage thérapeutique : Collagène, Durapatite, Matériaux biocompatibles, Minéraux, Reconstruction de crête alvéolaire, Substituts osseux, Trame osseuse.
- étiologie : Lâchage de suture.
- Animaux, Attribution aléatoire, Bovins, Chiens, Equus caballus, Facteurs temps, Fixateurs internes, Mandibule, Modèles animaux, Mâchoire partiellement édentée, Mâle, Prémolaire, Reconstruction de crête alvéolaire, Sécurité, Vis orthopédiques.
English descriptors
- KwdEn :
- Alveolar Ridge Augmentation (instrumentation), Alveolar Ridge Augmentation (methods), Animals, Bicuspid, Biocompatible Materials (therapeutic use), Bone Matrix (transplantation), Bone Remodeling (physiology), Bone Screws, Bone Substitutes (therapeutic use), Cattle, Collagen (therapeutic use), Dogs, Durapatite (therapeutic use), Horses, Internal Fixators, Jaw, Edentulous, Partially (pathology), Jaw, Edentulous, Partially (surgery), Male, Mandible (pathology), Mandible (surgery), Minerals (therapeutic use), Models, Animal, Random Allocation, Safety, Surgical Wound Dehiscence (etiology), Time Factors.
- MESH :
- chemical , therapeutic use : Biocompatible Materials, Bone Substitutes, Collagen, Durapatite, Minerals.
- etiology : Surgical Wound Dehiscence.
- instrumentation : Alveolar Ridge Augmentation.
- methods : Alveolar Ridge Augmentation.
- pathology : Jaw, Edentulous, Partially, Mandible.
- physiology : Bone Remodeling.
- surgery : Jaw, Edentulous, Partially, Mandible.
- transplantation : Bone Matrix.
- Animals, Bicuspid, Bone Screws, Cattle, Dogs, Horses, Internal Fixators, Male, Models, Animal, Random Allocation, Safety, Time Factors.
Abstract
The present investigation was performed to compare the biocompatibility, safety, and manageability of a newly developed bone block and a deproteinized bovine bone block (Bio-Oss) for the treatment of localized bone defects in a dog model. Two male beagle dogs were used for this study. The mandibular premolars were extracted and two saddle-type defects were created bilaterally in the edentulous area. The defects were filled according to a randomized design with Bio-Oss bone block or with an equine hydroxyapatite plus collagen bone block (eHAC). Most control and test sites developed dehiscences during healing. After 4 weeks, the animals were euthanized and each hemimandible was prepared for histologic examination. No significant difference in terms of local tolerance was observed between test and control sites, and test and control sites showed similar histologic findings. However, a significant difference was noticed between the Bio-Oss block and the new bone block in terms of manageability.
PubMed: 19146056
Affiliations:
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Le document en format XML
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<term>Biocompatible Materials (therapeutic use)</term>
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<term>Bone Remodeling (physiology)</term>
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<term>Collagen (therapeutic use)</term>
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<term>Durapatite (therapeutic use)</term>
<term>Horses</term>
<term>Internal Fixators</term>
<term>Jaw, Edentulous, Partially (pathology)</term>
<term>Jaw, Edentulous, Partially (surgery)</term>
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<term>Mandible (surgery)</term>
<term>Minerals (therapeutic use)</term>
<term>Models, Animal</term>
<term>Random Allocation</term>
<term>Safety</term>
<term>Surgical Wound Dehiscence (etiology)</term>
<term>Time Factors</term>
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<term>Durapatite (usage thérapeutique)</term>
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<term>Prémolaire</term>
<term>Reconstruction de crête alvéolaire ()</term>
<term>Reconstruction de crête alvéolaire (instrumentation)</term>
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<front><div type="abstract" xml:lang="en">The present investigation was performed to compare the biocompatibility, safety, and manageability of a newly developed bone block and a deproteinized bovine bone block (Bio-Oss) for the treatment of localized bone defects in a dog model. Two male beagle dogs were used for this study. The mandibular premolars were extracted and two saddle-type defects were created bilaterally in the edentulous area. The defects were filled according to a randomized design with Bio-Oss bone block or with an equine hydroxyapatite plus collagen bone block (eHAC). Most control and test sites developed dehiscences during healing. After 4 weeks, the animals were euthanized and each hemimandible was prepared for histologic examination. No significant difference in terms of local tolerance was observed between test and control sites, and test and control sites showed similar histologic findings. However, a significant difference was noticed between the Bio-Oss block and the new bone block in terms of manageability.</div>
</front>
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