Biocompatibility and manageability of a new fixable bone graft for the treatment of localized bone defects: preliminary study in a dog model.
Identifieur interne : 002560 ( Ncbi/Merge ); précédent : 002559; suivant : 002561Biocompatibility and manageability of a new fixable bone graft for the treatment of localized bone defects: preliminary study in a dog model.
Auteurs : Filippo Fontana [Italie] ; Isabella Rocchietta ; Claudia Dellavia ; Myron Nevins ; Massimo SimionSource :
- The International journal of periodontics & restorative dentistry [ 0198-7569 ] ; 2008.
Descripteurs français
- KwdFr :
- Animaux, Attribution aléatoire, Bovins, Chiens, Collagène (usage thérapeutique), Durapatite (usage thérapeutique), Equus caballus, Facteurs temps, Fixateurs internes, Lâchage de suture (étiologie), Mandibule (), Mandibule (anatomopathologie), Matériaux biocompatibles (usage thérapeutique), Minéraux (usage thérapeutique), Modèles animaux, Mâchoire partiellement édentée (), Mâchoire partiellement édentée (anatomopathologie), Mâle, Prémolaire, Reconstruction de crête alvéolaire (), Reconstruction de crête alvéolaire (instrumentation), Remodelage osseux (physiologie), Substituts osseux (usage thérapeutique), Sécurité, Trame osseuse (transplantation), Vis orthopédiques.
- MESH :
- anatomopathologie : Mandibule, Mâchoire partiellement édentée.
- physiologie : Remodelage osseux.
- usage thérapeutique : Collagène, Durapatite, Matériaux biocompatibles, Minéraux, Reconstruction de crête alvéolaire, Substituts osseux, Trame osseuse.
- étiologie : Lâchage de suture.
- Animaux, Attribution aléatoire, Bovins, Chiens, Equus caballus, Facteurs temps, Fixateurs internes, Mandibule, Modèles animaux, Mâchoire partiellement édentée, Mâle, Prémolaire, Reconstruction de crête alvéolaire, Sécurité, Vis orthopédiques.
English descriptors
- KwdEn :
- Alveolar Ridge Augmentation (instrumentation), Alveolar Ridge Augmentation (methods), Animals, Bicuspid, Biocompatible Materials (therapeutic use), Bone Matrix (transplantation), Bone Remodeling (physiology), Bone Screws, Bone Substitutes (therapeutic use), Cattle, Collagen (therapeutic use), Dogs, Durapatite (therapeutic use), Horses, Internal Fixators, Jaw, Edentulous, Partially (pathology), Jaw, Edentulous, Partially (surgery), Male, Mandible (pathology), Mandible (surgery), Minerals (therapeutic use), Models, Animal, Random Allocation, Safety, Surgical Wound Dehiscence (etiology), Time Factors.
- MESH :
- chemical , therapeutic use : Biocompatible Materials, Bone Substitutes, Collagen, Durapatite, Minerals.
- etiology : Surgical Wound Dehiscence.
- instrumentation : Alveolar Ridge Augmentation.
- methods : Alveolar Ridge Augmentation.
- pathology : Jaw, Edentulous, Partially, Mandible.
- physiology : Bone Remodeling.
- surgery : Jaw, Edentulous, Partially, Mandible.
- transplantation : Bone Matrix.
- Animals, Bicuspid, Bone Screws, Cattle, Dogs, Horses, Internal Fixators, Male, Models, Animal, Random Allocation, Safety, Time Factors.
Abstract
The present investigation was performed to compare the biocompatibility, safety, and manageability of a newly developed bone block and a deproteinized bovine bone block (Bio-Oss) for the treatment of localized bone defects in a dog model. Two male beagle dogs were used for this study. The mandibular premolars were extracted and two saddle-type defects were created bilaterally in the edentulous area. The defects were filled according to a randomized design with Bio-Oss bone block or with an equine hydroxyapatite plus collagen bone block (eHAC). Most control and test sites developed dehiscences during healing. After 4 weeks, the animals were euthanized and each hemimandible was prepared for histologic examination. No significant difference in terms of local tolerance was observed between test and control sites, and test and control sites showed similar histologic findings. However, a significant difference was noticed between the Bio-Oss block and the new bone block in terms of manageability.
PubMed: 19146056
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Two male beagle dogs were used for this study. The mandibular premolars were extracted and two saddle-type defects were created bilaterally in the edentulous area. The defects were filled according to a randomized design with Bio-Oss bone block or with an equine hydroxyapatite plus collagen bone block (eHAC). Most control and test sites developed dehiscences during healing. After 4 weeks, the animals were euthanized and each hemimandible was prepared for histologic examination. No significant difference in terms of local tolerance was observed between test and control sites, and test and control sites showed similar histologic findings. 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Two male beagle dogs were used for this study. The mandibular premolars were extracted and two saddle-type defects were created bilaterally in the edentulous area. The defects were filled according to a randomized design with Bio-Oss bone block or with an equine hydroxyapatite plus collagen bone block (eHAC). Most control and test sites developed dehiscences during healing. After 4 weeks, the animals were euthanized and each hemimandible was prepared for histologic examination. No significant difference in terms of local tolerance was observed between test and control sites, and test and control sites showed similar histologic findings. However, a significant difference was noticed between the Bio-Oss block and the new bone block in terms of manageability.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Fontana</LastName><ForeName>Filippo</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Implantology, School of Dentistry, University of Milano, Italy. filofontana@libero.it</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rocchietta</LastName><ForeName>Isabella</ForeName><Initials>I</Initials></Author><Author ValidYN="Y"><LastName>Dellavia</LastName><ForeName>Claudia</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Nevins</LastName><ForeName>Myron</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Simion</LastName><ForeName>Massimo</ForeName><Initials>M</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Int J Periodontics Restorative Dent</MedlineTA><NlmUniqueID>8200894</NlmUniqueID><ISSNLinking>0198-7569</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C077540">Bio-Oss</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D001672">Biocompatible Materials</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D018786">Bone Substitutes</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D008903">Minerals</NameOfSubstance></Chemical><Chemical><RegistryNumber>9007-34-5</RegistryNumber><NameOfSubstance UI="D003094">Collagen</NameOfSubstance></Chemical><Chemical><RegistryNumber>91D9GV0Z28</RegistryNumber><NameOfSubstance UI="D017886">Durapatite</NameOfSubstance></Chemical></ChemicalList><CitationSubset>D</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000540" MajorTopicYN="N">Alveolar Ridge Augmentation</DescriptorName><QualifierName UI="Q000295" MajorTopicYN="N">instrumentation</QualifierName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001641" MajorTopicYN="N">Bicuspid</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001672" MajorTopicYN="N">Biocompatible Materials</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001857" MajorTopicYN="N">Bone Matrix</DescriptorName><QualifierName UI="Q000637" MajorTopicYN="N">transplantation</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016723" 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MajorTopicYN="N">Horses</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016268" MajorTopicYN="N">Internal Fixators</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007576" MajorTopicYN="N">Jaw, Edentulous, Partially</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008334" MajorTopicYN="N">Mandible</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008903" MajorTopicYN="N">Minerals</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D023421" MajorTopicYN="N">Models, Animal</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011897" MajorTopicYN="N">Random Allocation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012449" MajorTopicYN="N">Safety</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013529" MajorTopicYN="N">Surgical Wound Dehiscence</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2009</Year><Month>1</Month><Day>17</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2009</Year><Month>1</Month><Day>17</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2009</Year><Month>4</Month><Day>1</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">19146056</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Italie</li></country></list><tree><noCountry><name sortKey="Dellavia, Claudia" sort="Dellavia, Claudia" uniqKey="Dellavia C" first="Claudia" last="Dellavia">Claudia Dellavia</name><name sortKey="Nevins, Myron" sort="Nevins, Myron" uniqKey="Nevins M" first="Myron" last="Nevins">Myron Nevins</name><name sortKey="Rocchietta, Isabella" sort="Rocchietta, Isabella" uniqKey="Rocchietta I" first="Isabella" last="Rocchietta">Isabella Rocchietta</name><name sortKey="Simion, Massimo" sort="Simion, Massimo" uniqKey="Simion M" first="Massimo" last="Simion">Massimo Simion</name></noCountry><country name="Italie"><noRegion><name sortKey="Fontana, Filippo" sort="Fontana, Filippo" uniqKey="Fontana F" first="Filippo" last="Fontana">Filippo Fontana</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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