Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans
Identifieur interne : 000F71 ( Main/Exploration ); précédent : 000F70; suivant : 000F72Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans
Auteurs : Paulo José Pasquali [Brésil] ; Marcelo Lucchesi Teixeira [Brésil] ; Thiago Altro De Oliveira [Brésil] ; Luis Guilherme Scavone De Macedo [Brésil] ; Antonio Carlos Aloise [Brésil] ; André Antonio Pelegrine [Brésil]Source :
- International Journal of Biomaterials [ 1687-8787 ] ; 2015.
Abstract
Url:
DOI: 10.1155/2015/121286
PubMed: 26543482
PubMed Central: 4620258
Affiliations:
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans</title>
<author><name sortKey="Pasquali, Paulo Jose" sort="Pasquali, Paulo Jose" uniqKey="Pasquali P" first="Paulo José" last="Pasquali">Paulo José Pasquali</name>
<affiliation wicri:level="1"><nlm:aff id="I1">Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea>
<wicri:noRegion>13045-755 Campinas</wicri:noRegion>
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<author><name sortKey="Teixeira, Marcelo Lucchesi" sort="Teixeira, Marcelo Lucchesi" uniqKey="Teixeira M" first="Marcelo Lucchesi" last="Teixeira">Marcelo Lucchesi Teixeira</name>
<affiliation wicri:level="1"><nlm:aff id="I2">Department of Prosthodontics, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff>
<country xml:lang="fr">Brésil</country>
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<wicri:noRegion>13045-755 Campinas</wicri:noRegion>
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<author><name sortKey="De Oliveira, Thiago Altro" sort="De Oliveira, Thiago Altro" uniqKey="De Oliveira T" first="Thiago Altro" last="De Oliveira">Thiago Altro De Oliveira</name>
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<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea>
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<author><name sortKey="De Macedo, Luis Guilherme Scavone" sort="De Macedo, Luis Guilherme Scavone" uniqKey="De Macedo L" first="Luis Guilherme Scavone" last="De Macedo">Luis Guilherme Scavone De Macedo</name>
<affiliation wicri:level="1"><nlm:aff id="I1">Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff>
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<author><name sortKey="Aloise, Antonio Carlos" sort="Aloise, Antonio Carlos" uniqKey="Aloise A" first="Antonio Carlos" last="Aloise">Antonio Carlos Aloise</name>
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</affiliation>
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<author><name sortKey="Pelegrine, Andre Antonio" sort="Pelegrine, Andre Antonio" uniqKey="Pelegrine A" first="André Antonio" last="Pelegrine">André Antonio Pelegrine</name>
<affiliation wicri:level="1"><nlm:aff id="I1">Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea>
<wicri:noRegion>13045-755 Campinas</wicri:noRegion>
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<series><title level="j">International Journal of Biomaterials</title>
<idno type="ISSN">1687-8787</idno>
<idno type="eISSN">1687-8795</idno>
<imprint><date when="2015">2015</date>
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<front><div type="abstract" xml:lang="en"><p><italic>Purpose</italic>
. To investigate the regenerative results obtained with the association of bone marrow aspirate concentrate using the Bone Marrow Aspirate Concentrate (BMAC) method to a xenogeneic bone graft (Bio-Oss) in sinus floor elevation. <italic>Materials and Methods</italic>
. Using a randomized controlled study design in eight consecutive patients (age of 55.4 ± 9.2 years), 16 sinus floor lift procedures were performed with Bio-Oss alone (control group, CG, <italic>n</italic>
= 8) or combined with bone marrow aspirate concentrate obtained via the BMAC method (test group, TG, <italic>n</italic>
= 8). Six months after the grafting procedures, bone biopsies were harvested during implant placement and were analyzed by histomorphometry. <italic>Results</italic>
. Histomorphometric analysis revealed a significantly higher amount (<italic>p</italic>
< 0.05) of vital mineralized tissue in TG when compared to the CG (55.15 ± 20.91% and 27.30 ± 5.55%, resp.). For nonvital mineralized tissue, TG presented a statistically higher level of Bio-Oss resorption (<italic>p</italic>
< 0.05) when compared with the CG (6.32 ± 12.03% and 22.79 ± 9.60%, resp.). Both groups (TG and CG) showed no significantly different levels (<italic>p</italic>
> 0.05) of nonmineralized tissue (38.53 ± 13.08% and 49.90 ± 7.64%, resp.). <italic>Conclusion</italic>
. The use of bone marrow concentrate obtained by BMAC method increased bone formation in sinus lift procedures.</p>
</div>
</front>
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<name sortKey="Aloise, Antonio Carlos" sort="Aloise, Antonio Carlos" uniqKey="Aloise A" first="Antonio Carlos" last="Aloise">Antonio Carlos Aloise</name>
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