Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans
Identifieur interne : 006113 ( Ncbi/Merge ); précédent : 006112; suivant : 006114Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans
Auteurs : Paulo José Pasquali [Brésil] ; Marcelo Lucchesi Teixeira [Brésil] ; Thiago Altro De Oliveira [Brésil] ; Luis Guilherme Scavone De Macedo [Brésil] ; Antonio Carlos Aloise [Brésil] ; André Antonio Pelegrine [Brésil]Source :
- International Journal of Biomaterials [ 1687-8787 ] ; 2015.
Abstract
Url:
DOI: 10.1155/2015/121286
PubMed: 26543482
PubMed Central: 4620258
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 002D27
- to stream Pmc, to step Curation: 002D27
- to stream Pmc, to step Checkpoint: 000C76
Links to Exploration step
PMC:4620258Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans</title><author><name sortKey="Pasquali, Paulo Jose" sort="Pasquali, Paulo Jose" uniqKey="Pasquali P" first="Paulo José" last="Pasquali">Paulo José Pasquali</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea><wicri:noRegion>13045-755 Campinas</wicri:noRegion></affiliation></author><author><name sortKey="Teixeira, Marcelo Lucchesi" sort="Teixeira, Marcelo Lucchesi" uniqKey="Teixeira M" first="Marcelo Lucchesi" last="Teixeira">Marcelo Lucchesi Teixeira</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Prosthodontics, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Prosthodontics, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea><wicri:noRegion>13045-755 Campinas</wicri:noRegion></affiliation></author><author><name sortKey="De Oliveira, Thiago Altro" sort="De Oliveira, Thiago Altro" uniqKey="De Oliveira T" first="Thiago Altro" last="De Oliveira">Thiago Altro De Oliveira</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea><wicri:noRegion>13045-755 Campinas</wicri:noRegion></affiliation></author><author><name sortKey="De Macedo, Luis Guilherme Scavone" sort="De Macedo, Luis Guilherme Scavone" uniqKey="De Macedo L" first="Luis Guilherme Scavone" last="De Macedo">Luis Guilherme Scavone De Macedo</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea><wicri:noRegion>13045-755 Campinas</wicri:noRegion></affiliation></author><author><name sortKey="Aloise, Antonio Carlos" sort="Aloise, Antonio Carlos" uniqKey="Aloise A" first="Antonio Carlos" last="Aloise">Antonio Carlos Aloise</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea><wicri:noRegion>13045-755 Campinas</wicri:noRegion></affiliation></author><author><name sortKey="Pelegrine, Andre Antonio" sort="Pelegrine, Andre Antonio" uniqKey="Pelegrine A" first="André Antonio" last="Pelegrine">André Antonio Pelegrine</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea><wicri:noRegion>13045-755 Campinas</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26543482</idno><idno type="pmc">4620258</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620258</idno><idno type="RBID">PMC:4620258</idno><idno type="doi">10.1155/2015/121286</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">002D27</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002D27</idno><idno type="wicri:Area/Pmc/Curation">002D27</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002D27</idno><idno type="wicri:Area/Pmc/Checkpoint">000C76</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000C76</idno><idno type="wicri:Area/Ncbi/Merge">006113</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans</title><author><name sortKey="Pasquali, Paulo Jose" sort="Pasquali, Paulo Jose" uniqKey="Pasquali P" first="Paulo José" last="Pasquali">Paulo José Pasquali</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea><wicri:noRegion>13045-755 Campinas</wicri:noRegion></affiliation></author><author><name sortKey="Teixeira, Marcelo Lucchesi" sort="Teixeira, Marcelo Lucchesi" uniqKey="Teixeira M" first="Marcelo Lucchesi" last="Teixeira">Marcelo Lucchesi Teixeira</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Prosthodontics, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Prosthodontics, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea><wicri:noRegion>13045-755 Campinas</wicri:noRegion></affiliation></author><author><name sortKey="De Oliveira, Thiago Altro" sort="De Oliveira, Thiago Altro" uniqKey="De Oliveira T" first="Thiago Altro" last="De Oliveira">Thiago Altro De Oliveira</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea><wicri:noRegion>13045-755 Campinas</wicri:noRegion></affiliation></author><author><name sortKey="De Macedo, Luis Guilherme Scavone" sort="De Macedo, Luis Guilherme Scavone" uniqKey="De Macedo L" first="Luis Guilherme Scavone" last="De Macedo">Luis Guilherme Scavone De Macedo</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea><wicri:noRegion>13045-755 Campinas</wicri:noRegion></affiliation></author><author><name sortKey="Aloise, Antonio Carlos" sort="Aloise, Antonio Carlos" uniqKey="Aloise A" first="Antonio Carlos" last="Aloise">Antonio Carlos Aloise</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea><wicri:noRegion>13045-755 Campinas</wicri:noRegion></affiliation></author><author><name sortKey="Pelegrine, Andre Antonio" sort="Pelegrine, Andre Antonio" uniqKey="Pelegrine A" first="André Antonio" last="Pelegrine">André Antonio Pelegrine</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas</wicri:regionArea><wicri:noRegion>13045-755 Campinas</wicri:noRegion></affiliation></author></analytic><series><title level="j">International Journal of Biomaterials</title><idno type="ISSN">1687-8787</idno><idno type="eISSN">1687-8795</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><italic>Purpose</italic>. To investigate the regenerative results obtained with the association of bone marrow aspirate concentrate using the Bone Marrow Aspirate Concentrate (BMAC) method to a xenogeneic bone graft (Bio-Oss) in sinus floor elevation. <italic>Materials and Methods</italic>. Using a randomized controlled study design in eight consecutive patients (age of 55.4 ± 9.2 years), 16 sinus floor lift procedures were performed with Bio-Oss alone (control group, CG, <italic>n</italic> = 8) or combined with bone marrow aspirate concentrate obtained via the BMAC method (test group, TG, <italic>n</italic> = 8). Six months after the grafting procedures, bone biopsies were harvested during implant placement and were analyzed by histomorphometry. <italic>Results</italic>. Histomorphometric analysis revealed a significantly higher amount (<italic>p</italic> < 0.05) of vital mineralized tissue in TG when compared to the CG (55.15 ± 20.91% and 27.30 ± 5.55%, resp.). For nonvital mineralized tissue, TG presented a statistically higher level of Bio-Oss resorption (<italic>p</italic> < 0.05) when compared with the CG (6.32 ± 12.03% and 22.79 ± 9.60%, resp.). Both groups (TG and CG) showed no significantly different levels (<italic>p</italic> > 0.05) of nonmineralized tissue (38.53 ± 13.08% and 49.90 ± 7.64%, resp.). <italic>Conclusion</italic>. The use of bone marrow concentrate obtained by BMAC method increased bone formation in sinus lift procedures.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Chaushu, G" uniqKey="Chaushu G">G. Chaushu</name></author><author><name sortKey="Mardinger, O" uniqKey="Mardinger O">O. Mardinger</name></author><author><name sortKey="Peleg, M" uniqKey="Peleg M">M. Peleg</name></author><author><name sortKey="Ghelfan, O" uniqKey="Ghelfan O">O. Ghelfan</name></author><author><name sortKey="Nissan, J" uniqKey="Nissan J">J. Nissan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boyne, P J" uniqKey="Boyne P">P. J. Boyne</name></author><author><name sortKey="James, R A" uniqKey="James R">R. A. James</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Prolo, D J" uniqKey="Prolo D">D. J. Prolo</name></author><author><name sortKey="Rodrigo, J J" uniqKey="Rodrigo J">J. J. Rodrigo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jensen, S S" uniqKey="Jensen S">S. S. Jensen</name></author><author><name sortKey="Terheyden, H" uniqKey="Terheyden H">H. Terheyden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ferreira, C E A" uniqKey="Ferreira C">C. E. A. Ferreira</name></author><author><name sortKey="Novaes, A B" uniqKey="Novaes A">A. B. Novaes</name></author><author><name sortKey="Haraszthy, V I" uniqKey="Haraszthy V">V. I. Haraszthy</name></author><author><name sortKey="Bittencourt, M" uniqKey="Bittencourt M">M. Bittencourt</name></author><author><name sortKey="Martinelli, C B" uniqKey="Martinelli C">C. B. Martinelli</name></author><author><name sortKey="Luczyszyn, S M" uniqKey="Luczyszyn S">S. M. Luczyszyn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jensen, T" uniqKey="Jensen T">T. Jensen</name></author><author><name sortKey="Schou, S" uniqKey="Schou S">S. Schou</name></author><author><name sortKey="Stavropoulos, A" uniqKey="Stavropoulos A">A. Stavropoulos</name></author><author><name sortKey="Terheyden, H" uniqKey="Terheyden H">H. Terheyden</name></author><author><name sortKey="Holmstrup, P" uniqKey="Holmstrup P">P. Holmstrup</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stacchi, C" uniqKey="Stacchi C">C. Stacchi</name></author><author><name sortKey="Orsini, G" uniqKey="Orsini G">G. Orsini</name></author><author><name sortKey="Di Iorio, D" uniqKey="Di Iorio D">D. Di Iorio</name></author><author><name sortKey="Breschi, L" uniqKey="Breschi L">L. Breschi</name></author><author><name sortKey="Di Lenarda, R" uniqKey="Di Lenarda R">R. Di Lenarda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Contar, C M M" uniqKey="Contar C">C. M. M. Contar</name></author><author><name sortKey="Sarot, J R" uniqKey="Sarot J">J. R. Sarot</name></author><author><name sortKey="Da Costa, M B" uniqKey="Da Costa M">M. B. da Costa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cordaro, L" uniqKey="Cordaro L">L. Cordaro</name></author><author><name sortKey="Bosshardt, D D" uniqKey="Bosshardt D">D. D. Bosshardt</name></author><author><name sortKey="Palattella, P" uniqKey="Palattella P">P. Palattella</name></author><author><name sortKey="Rao, W" uniqKey="Rao W">W. Rao</name></author><author><name sortKey="Serino, G" uniqKey="Serino G">G. Serino</name></author><author><name sortKey="Chiapasco, M" uniqKey="Chiapasco M">M. Chiapasco</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frenken, J W F H" uniqKey="Frenken J">J. W. F. H. Frenken</name></author><author><name sortKey="Bouwman, W F" uniqKey="Bouwman W">W. F. Bouwman</name></author><author><name sortKey="Bravenboer, N" uniqKey="Bravenboer N">N. Bravenboer</name></author><author><name sortKey="Zijderveld, S A" uniqKey="Zijderveld S">S. A. Zijderveld</name></author><author><name sortKey="Schulten, E A J M" uniqKey="Schulten E">E. A. J. M. Schulten</name></author><author><name sortKey="Ten Bruggenkate, C M" uniqKey="Ten Bruggenkate C">C. M. Ten Bruggenkate</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gurevitch, O" uniqKey="Gurevitch O">O. Gurevitch</name></author><author><name sortKey="Kurkalli, B G S" uniqKey="Kurkalli B">B. G. S. Kurkalli</name></author><author><name sortKey="Prigozhina, T" uniqKey="Prigozhina T">T. Prigozhina</name></author><author><name sortKey="Kasir, J" uniqKey="Kasir J">J. Kasir</name></author><author><name sortKey="Gaft, A" uniqKey="Gaft A">A. Gaft</name></author><author><name sortKey="Slavin, S" uniqKey="Slavin S">S. Slavin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kale, S" uniqKey="Kale S">S. Kale</name></author><author><name sortKey="Long, M W" uniqKey="Long M">M. W. Long</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yamamoto, N" uniqKey="Yamamoto N">N. Yamamoto</name></author><author><name sortKey="Furuya, K" uniqKey="Furuya K">K. Furuya</name></author><author><name sortKey="Hanada, K" uniqKey="Hanada K">K. Hanada</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kaigler, D" uniqKey="Kaigler D">D. Kaigler</name></author><author><name sortKey="Krebsbach, P H" uniqKey="Krebsbach P">P. H. Krebsbach</name></author><author><name sortKey="Polverini, P J" uniqKey="Polverini P">P. J. Polverini</name></author><author><name sortKey="Mooney, D J" uniqKey="Mooney D">D. J. Mooney</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lucarelli, E" uniqKey="Lucarelli E">E. Lucarelli</name></author><author><name sortKey="Fini, M" uniqKey="Fini M">M. Fini</name></author><author><name sortKey="Beccheroni, A" uniqKey="Beccheroni A">A. Beccheroni</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sauerbier, S" uniqKey="Sauerbier S">S. Sauerbier</name></author><author><name sortKey="Stricker, A" uniqKey="Stricker A">A. Stricker</name></author><author><name sortKey="Kuschnierz, J" uniqKey="Kuschnierz J">J. Kuschnierz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sauerbier, S" uniqKey="Sauerbier S">S. Sauerbier</name></author><author><name sortKey="Rickert, D" uniqKey="Rickert D">D. Rickert</name></author><author><name sortKey="Gutwald, R" uniqKey="Gutwald R">R. Gutwald</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rickert, D" uniqKey="Rickert D">D. Rickert</name></author><author><name sortKey="Sauerbier, S" uniqKey="Sauerbier S">S. Sauerbier</name></author><author><name sortKey="Nagursky, H" uniqKey="Nagursky H">H. Nagursky</name></author><author><name sortKey="Menne, D" uniqKey="Menne D">D. Menne</name></author><author><name sortKey="Vissink, A" uniqKey="Vissink A">A. Vissink</name></author><author><name sortKey="Raghoebar, G M" uniqKey="Raghoebar G">G. M. Raghoebar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, D Z" uniqKey="Lee D">D. Z. Lee</name></author><author><name sortKey="Chen, S T" uniqKey="Chen S">S. T. Chen</name></author><author><name sortKey="Darby, I B" uniqKey="Darby I">I. B. Darby</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sampson, S" uniqKey="Sampson S">S. Sampson</name></author><author><name sortKey="Botto Van Bemden, A" uniqKey="Botto Van Bemden A">A. Botto-van Bemden</name></author><author><name sortKey="Aufiero, D" uniqKey="Aufiero D">D. Aufiero</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wallace, S S" uniqKey="Wallace S">S. S. Wallace</name></author><author><name sortKey="Froum, S J" uniqKey="Froum S">S. J. Froum</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Del Fabbro, M" uniqKey="Del Fabbro M">M. Del Fabbro</name></author><author><name sortKey="Testori, T" uniqKey="Testori T">T. Testori</name></author><author><name sortKey="Francetti, L" uniqKey="Francetti L">L. Francetti</name></author><author><name sortKey="Weinstein, R" uniqKey="Weinstein R">R. Weinstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nkenke, E" uniqKey="Nkenke E">E. Nkenke</name></author><author><name sortKey="Stelzle, F" uniqKey="Stelzle F">F. Stelzle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klijn, R J" uniqKey="Klijn R">R. J. Klijn</name></author><author><name sortKey="Meijer, G J" uniqKey="Meijer G">G. J. Meijer</name></author><author><name sortKey="Bronkhorst, E M" uniqKey="Bronkhorst E">E. M. Bronkhorst</name></author><author><name sortKey="Jansen, J A" uniqKey="Jansen J">J. A. Jansen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klijn, R J" uniqKey="Klijn R">R. J. Klijn</name></author><author><name sortKey="Meijer, G J" uniqKey="Meijer G">G. J. Meijer</name></author><author><name sortKey="Bronkhorst, E M" uniqKey="Bronkhorst E">E. M. Bronkhorst</name></author><author><name sortKey="Jansen, J A" uniqKey="Jansen J">J. A. Jansen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Berglundh, T" uniqKey="Berglundh T">T. Berglundh</name></author><author><name sortKey="Lindhe, J" uniqKey="Lindhe J">J. Lindhe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Piattelli, M" uniqKey="Piattelli M">M. Piattelli</name></author><author><name sortKey="Favero, G A" uniqKey="Favero G">G. A. Favero</name></author><author><name sortKey="Scarano, A" uniqKey="Scarano A">A. Scarano</name></author><author><name sortKey="Orsini, G" uniqKey="Orsini G">G. Orsini</name></author><author><name sortKey="Piattelli, A" uniqKey="Piattelli A">A. Piattelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hallman, M" uniqKey="Hallman M">M. Hallman</name></author><author><name sortKey="Lundgren, S" uniqKey="Lundgren S">S. Lundgren</name></author><author><name sortKey="Sennerby, L" uniqKey="Sennerby L">L. Sennerby</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sollazzo, V" uniqKey="Sollazzo V">V. Sollazzo</name></author><author><name sortKey="Palmieri, A" uniqKey="Palmieri A">A. Palmieri</name></author><author><name sortKey="Scapoli, L" uniqKey="Scapoli L">L. Scapoli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Esfahanizadeh, N" uniqKey="Esfahanizadeh N">N. Esfahanizadeh</name></author><author><name sortKey="Rokn, A R" uniqKey="Rokn A">A. R. Rokn</name></author><author><name sortKey="Paknejad, M" uniqKey="Paknejad M">M. Paknejad</name></author><author><name sortKey="Motahari, P" uniqKey="Motahari P">P. Motahari</name></author><author><name sortKey="Daneshparvar, H" uniqKey="Daneshparvar H">H. Daneshparvar</name></author><author><name sortKey="Shamshiri, A R" uniqKey="Shamshiri A">A. R. Shamshiri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pelegrine, A A" uniqKey="Pelegrine A">A. A. Pelegrine</name></author><author><name sortKey="Da Costa, C E S" uniqKey="Da Costa C">C. E. S. da Costa</name></author><author><name sortKey="Correa, M E P" uniqKey="Correa M">M. E. P. Correa</name></author><author><name sortKey="Marques, J F C" uniqKey="Marques J">J. F. C. Marques</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Da Costa, C E S" uniqKey="Da Costa C">C. E. S. da Costa</name></author><author><name sortKey="Pelegrine, A A" uniqKey="Pelegrine A">A. A. Pelegrine</name></author><author><name sortKey="Fagundes, D J" uniqKey="Fagundes D">D. J. Fagundes</name></author><author><name sortKey="De Jesus Simoes, M" uniqKey="De Jesus Simoes M">M. de Jesus Simoes</name></author><author><name sortKey="Taha, M O" uniqKey="Taha M">M. O. Taha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pelegrine, A A" uniqKey="Pelegrine A">A. A. Pelegrine</name></author><author><name sortKey="Aloise, A C" uniqKey="Aloise A">A. C. Aloise</name></author><author><name sortKey="Zimmermann, A" uniqKey="Zimmermann A">A. Zimmermann</name></author><author><name sortKey="De Mello E Oliveira, R" uniqKey="De Mello E Oliveira R">R. de Mello e Oliveira</name></author><author><name sortKey="Ferreira, L M" uniqKey="Ferreira L">L. M. Ferreira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nagata, M" uniqKey="Nagata M">M. Nagata</name></author><author><name sortKey="Hoshina, H" uniqKey="Hoshina H">H. Hoshina</name></author><author><name sortKey="Li, M" uniqKey="Li M">M. Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, F" uniqKey="Chen F">F. Chen</name></author><author><name sortKey="Feng, X" uniqKey="Feng X">X. Feng</name></author><author><name sortKey="Wu, W" uniqKey="Wu W">W. Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sakai, S" uniqKey="Sakai S">S. Sakai</name></author><author><name sortKey="Mishima, H" uniqKey="Mishima H">H. Mishima</name></author><author><name sortKey="Ishii, T" uniqKey="Ishii T">T. Ishii</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sauerbier, S" uniqKey="Sauerbier S">S. Sauerbier</name></author><author><name sortKey="Stricker, A" uniqKey="Stricker A">A. Stricker</name></author><author><name sortKey="Kuschnierz, J" uniqKey="Kuschnierz J">J. Kuschnierz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lucarelli, E" uniqKey="Lucarelli E">E. Lucarelli</name></author><author><name sortKey="Donati, D" uniqKey="Donati D">D. Donati</name></author><author><name sortKey="Cenacchi, A" uniqKey="Cenacchi A">A. Cenacchi</name></author><author><name sortKey="Fornasari, P M" uniqKey="Fornasari P">P. M. Fornasari</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Int J Biomater</journal-id><journal-id journal-id-type="iso-abbrev">Int J Biomater</journal-id><journal-id journal-id-type="publisher-id">IJBM</journal-id><journal-title-group><journal-title>International Journal of Biomaterials</journal-title></journal-title-group><issn pub-type="ppub">1687-8787</issn><issn pub-type="epub">1687-8795</issn><publisher><publisher-name>Hindawi Publishing Corporation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">26543482</article-id><article-id pub-id-type="pmc">4620258</article-id><article-id pub-id-type="doi">10.1155/2015/121286</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Pasquali</surname><given-names>Paulo José</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Teixeira</surname><given-names>Marcelo Lucchesi</given-names></name><xref ref-type="aff" rid="I2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>de Oliveira</surname><given-names>Thiago Altro</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>de Macedo</surname><given-names>Luis Guilherme Scavone</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Aloise</surname><given-names>Antonio Carlos</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Pelegrine</surname><given-names>André Antonio</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib></contrib-group><aff id="I1"><sup>1</sup>Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</aff><aff id="I2"><sup>2</sup>Department of Prosthodontics, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil</aff><author-notes><corresp id="cor1">*André Antonio Pelegrine: <email>pelegrineandre@gmail.com</email></corresp><fn fn-type="other"><p>Academic Editor: Sean Peel</p></fn></author-notes><pub-date pub-type="ppub"><year>2015</year></pub-date><pub-date pub-type="epub"><day>12</day><month>10</month><year>2015</year></pub-date><volume>2015</volume><elocation-id>121286</elocation-id><history><date date-type="received"><day>14</day><month>6</month><year>2015</year></date><date date-type="rev-recd"><day>3</day><month>9</month><year>2015</year></date><date date-type="accepted"><day>27</day><month>9</month><year>2015</year></date></history><permissions><copyright-statement>Copyright © 2015 Paulo José Pasquali et al.</copyright-statement><copyright-year>2015</copyright-year><license xlink:href="https://creativecommons.org/licenses/by/3.0/"><license-p>This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><p><italic>Purpose</italic>. To investigate the regenerative results obtained with the association of bone marrow aspirate concentrate using the Bone Marrow Aspirate Concentrate (BMAC) method to a xenogeneic bone graft (Bio-Oss) in sinus floor elevation. <italic>Materials and Methods</italic>. Using a randomized controlled study design in eight consecutive patients (age of 55.4 ± 9.2 years), 16 sinus floor lift procedures were performed with Bio-Oss alone (control group, CG, <italic>n</italic> = 8) or combined with bone marrow aspirate concentrate obtained via the BMAC method (test group, TG, <italic>n</italic> = 8). Six months after the grafting procedures, bone biopsies were harvested during implant placement and were analyzed by histomorphometry. <italic>Results</italic>. Histomorphometric analysis revealed a significantly higher amount (<italic>p</italic> < 0.05) of vital mineralized tissue in TG when compared to the CG (55.15 ± 20.91% and 27.30 ± 5.55%, resp.). For nonvital mineralized tissue, TG presented a statistically higher level of Bio-Oss resorption (<italic>p</italic> < 0.05) when compared with the CG (6.32 ± 12.03% and 22.79 ± 9.60%, resp.). Both groups (TG and CG) showed no significantly different levels (<italic>p</italic> > 0.05) of nonmineralized tissue (38.53 ± 13.08% and 49.90 ± 7.64%, resp.). <italic>Conclusion</italic>. The use of bone marrow concentrate obtained by BMAC method increased bone formation in sinus lift procedures.</p></abstract></article-meta></front><floats-group><fig id="fig1" orientation="portrait" position="float"><label>Figure 1</label><caption><p>Cone-beam computed tomography scans of the posterior maxillary region.</p></caption><graphic xlink:href="IJBM2015-121286.001"></graphic></fig><fig id="fig2" orientation="portrait" position="float"><label>Figure 2</label><caption><p>Bone marrow was collected from all the patients by aspiration through a puncture 2 cm laterocaudally from the superior posterior iliac crest.</p></caption><graphic xlink:href="IJBM2015-121286.002"></graphic></fig><fig id="fig3" orientation="portrait" position="float"><label>Figure 3</label><caption><p>After centrifugation for 14 minutes, two phases were obtained within the container: (1) the supernatant plasma above and (2) precipitated bone marrow cells concentrate below.</p></caption><graphic xlink:href="IJBM2015-121286.003"></graphic></fig><fig id="fig4" orientation="portrait" position="float"><label>Figure 4</label><caption><p>The Schneiderian membrane seen through the lateral window in the maxillary sinus.</p></caption><graphic xlink:href="IJBM2015-121286.004"></graphic></fig><fig id="fig5" orientation="portrait" position="float"><label>Figure 5</label><caption><p>Maxillary sinus was grafted with xenogeneic bone from bovine hydroxyapatite.</p></caption><graphic xlink:href="IJBM2015-121286.005"></graphic></fig><fig id="fig6" orientation="portrait" position="float"><label>Figure 6</label><caption><p>Xenograft combined with the bone marrow concentrate, immediately before being used.</p></caption><graphic xlink:href="IJBM2015-121286.006"></graphic></fig><fig id="fig7" orientation="portrait" position="float"><label>Figure 7</label><caption><p>Bone specimens removed by a trephine bur.</p></caption><graphic xlink:href="IJBM2015-121286.007"></graphic></fig><fig id="fig8" orientation="portrait" position="float"><label>Figure 8</label><caption><p>Dental implants (Blackfix, AS Technology, São José dos Campos, Brazil) immediately after they are placed.</p></caption><graphic xlink:href="IJBM2015-121286.008"></graphic></fig><fig id="fig9" orientation="portrait" position="float"><label>Figure 9</label><caption><p>(a) Histological image of control group, stained by Masson's trichrome technique. Augmentation 20x. (b) Histological image of experimental group, stained by Masson's trichrome technique. Augmentation 20x.</p></caption><graphic xlink:href="IJBM2015-121286.009"></graphic></fig><table-wrap id="tab1" orientation="portrait" position="float"><label>Table 1</label><caption><p>Statistical comparison of mean values (in percentage, %) between CG and TG.</p></caption><table frame="hsides" rules="groups"><thead><tr><th align="center" colspan="4" rowspan="1">Histomorphometric intergroup analysis</th></tr><tr><th align="left" rowspan="2" colspan="1">Tissues</th><th align="center" colspan="2" rowspan="1">Groups</th><th align="center" rowspan="2" colspan="1"><italic>p</italic> value</th></tr><tr><th align="center" rowspan="1" colspan="1">CG</th><th align="center" rowspan="1" colspan="1">TG</th></tr></thead><tbody><tr><td align="left" rowspan="1" colspan="1">NVMT</td><td align="center" rowspan="1" colspan="1">22.79 ± 9.60</td><td align="center" rowspan="1" colspan="1">6.32 ± 12.03</td><td align="center" rowspan="1" colspan="1">0.006</td></tr><tr><td align="left" rowspan="1" colspan="1">VMT</td><td align="center" rowspan="1" colspan="1">27.30 ± 5.55</td><td align="center" rowspan="1" colspan="1">55.15 ± 20.91</td><td align="center" rowspan="1" colspan="1">0.002</td></tr><tr><td align="left" rowspan="1" colspan="1">NMT</td><td align="center" rowspan="1" colspan="1">49.90 ± 7.64</td><td align="center" rowspan="1" colspan="1">38.53 ± 13.08</td><td align="center" rowspan="1" colspan="1">0.09</td></tr></tbody></table><table-wrap-foot><fn><p>NVMT: nonvital mineralized tissue, VMT: vital mineralized tissue, NMT: nonmineralized tissue, CG: control group, and TG: test group.</p></fn><fn><p>Statistically significant <italic>p</italic> ≤ 0.05 (Mann-Whitney with correction by Sidak-Bonferroni test).</p></fn></table-wrap-foot></table-wrap></floats-group></pmc><affiliations><list><country><li>Brésil</li></country></list><tree><country name="Brésil"><noRegion><name sortKey="Pasquali, Paulo Jose" sort="Pasquali, Paulo Jose" uniqKey="Pasquali P" first="Paulo José" last="Pasquali">Paulo José Pasquali</name></noRegion><name sortKey="Aloise, Antonio Carlos" sort="Aloise, Antonio Carlos" uniqKey="Aloise A" first="Antonio Carlos" last="Aloise">Antonio Carlos Aloise</name><name sortKey="De Macedo, Luis Guilherme Scavone" sort="De Macedo, Luis Guilherme Scavone" uniqKey="De Macedo L" first="Luis Guilherme Scavone" last="De Macedo">Luis Guilherme Scavone De Macedo</name><name sortKey="De Oliveira, Thiago Altro" sort="De Oliveira, Thiago Altro" uniqKey="De Oliveira T" first="Thiago Altro" last="De Oliveira">Thiago Altro De Oliveira</name><name sortKey="Pelegrine, Andre Antonio" sort="Pelegrine, Andre Antonio" uniqKey="Pelegrine A" first="André Antonio" last="Pelegrine">André Antonio Pelegrine</name><name sortKey="Teixeira, Marcelo Lucchesi" sort="Teixeira, Marcelo Lucchesi" uniqKey="Teixeira M" first="Marcelo Lucchesi" last="Teixeira">Marcelo Lucchesi Teixeira</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006113 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 006113 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Ncbi
|étape= Merge
|type= RBID
|clé= PMC:4620258
|texte= Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:26543482" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a EdenteV2
| This area was generated with Dilib version V0.6.32. |  |