Upregulation of transforming growth factor-beta1 and vascular endothelial growth factor gene and protein expression in cyclosporin-induced overgrown edentulous gingiva in rats.
Identifieur interne : 007113 ( Main/Curation ); précédent : 007112; suivant : 007114Upregulation of transforming growth factor-beta1 and vascular endothelial growth factor gene and protein expression in cyclosporin-induced overgrown edentulous gingiva in rats.
Auteurs : Yen-Teen Chen [Taïwan] ; Hsiao-Pei Tu ; Yu-Tang Chin ; E-Chin Shen ; Cheng-Yang Chiang ; Ching-Hwa Gau ; Earl FuSource :
- Journal of periodontology [ 0022-3492 ] ; 2005.
Descripteurs français
- KwdFr :
- ARN messager (analyse), Animaux, Bouche édentée (anatomopathologie), Ciclosporine (effets indésirables), Croissance exagérée de la gencive (), Facteur de croissance IGF-I (), Facteur de croissance endothéliale vasculaire de type A (), Facteur de croissance transformant bêta (), Facteur de croissance transformant bêta-1, Gencive (), Gencive (anatomopathologie), Immunohistochimie, Mâle, Protéines proto-oncogènes c-sis (), Rat Sprague-Dawley, Rats, Réaction de polymérisation en chaîne, Régulation positive ().
- MESH :
- analyse : ARN messager.
- anatomopathologie : Bouche édentée, Gencive.
- effets indésirables : Ciclosporine.
- Animaux, Croissance exagérée de la gencive, Facteur de croissance IGF-I, Facteur de croissance endothéliale vasculaire de type A, Facteur de croissance transformant bêta, Facteur de croissance transformant bêta-1, Gencive, Immunohistochimie, Mâle, Protéines proto-oncogènes c-sis, Rat Sprague-Dawley, Rats, Réaction de polymérisation en chaîne, Régulation positive.
English descriptors
- KwdEn :
- Animals, Cyclosporine (adverse effects), Gingiva (drug effects), Gingiva (pathology), Gingival Overgrowth (chemically induced), Immunohistochemistry, Insulin-Like Growth Factor I (drug effects), Male, Mouth, Edentulous (pathology), Polymerase Chain Reaction, Proto-Oncogene Proteins c-sis (drug effects), RNA, Messenger (analysis), Rats, Rats, Sprague-Dawley, Transforming Growth Factor beta (drug effects), Transforming Growth Factor beta1, Up-Regulation (drug effects), Vascular Endothelial Growth Factor A (drug effects).
- MESH :
- chemical , adverse effects : Cyclosporine.
- chemical , analysis : RNA, Messenger.
- chemically induced : Gingival Overgrowth.
- drug effects : Gingiva, Insulin-Like Growth Factor I, Proto-Oncogene Proteins c-sis, Transforming Growth Factor beta, Up-Regulation, Vascular Endothelial Growth Factor A.
- pathology : Gingiva, Mouth, Edentulous.
- Animals, Immunohistochemistry, Male, Polymerase Chain Reaction, Rats, Rats, Sprague-Dawley, Transforming Growth Factor beta1.
Abstract
To examine the effects of cyclosporin A (CsA) on the expression of growth factors in induced gingival overgrowth with limited contributing factors arising from local inflammation caused by bacterial plaque, this study of gingival overgrowth was designed on the edentulous ridge of rats.
DOI: 10.1902/jop.2005.76.12.2267
PubMed: 16332239
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