Children’s vaccines do not induce cross reactivity against SARS-CoV
Identifieur interne : 000F18 ( Main/Curation ); précédent : 000F17; suivant : 000F19Children’s vaccines do not induce cross reactivity against SARS-CoV
Auteurs : Yang Yu [République populaire de Chine] ; Huali Jin [République populaire de Chine] ; Ze Chen [République populaire de Chine] ; Qingling L. Yu [République populaire de Chine] ; Yijie J. Ma [République populaire de Chine] ; Xiaolin L. Sun [République populaire de Chine] ; Bin Wang [République populaire de Chine]Source :
- Journal of Clinical Pathology [ 0021-9746 ] ; 2007-02.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antiviraux (sang), Enfant, Enfant d'âge préscolaire, Humains, Immunisation, Lymphocytes T (immunologie), Nourrisson, Réactions croisées (immunologie), Souris, Souris de lignée C57BL, Syndrome respiratoire aigu sévère (immunologie), Sérums immuns (immunologie), Test ELISA (), Vaccins (immunologie), Virus du SRAS (immunologie).
- MESH :
English descriptors
- KwdEn :
- Animals, Antibodies, Viral (blood), Child, Child, Preschool, Cross Reactions (immunology), Enzyme-Linked Immunosorbent Assay (methods), Humans, Immune Sera (immunology), Immunization, Infant, Mice, Mice, Inbred C57BL, SARS CoV, SARS coronavirus, SARS Virus (immunology), SARS, severe acute respiratory syndrome, Severe Acute Respiratory Syndrome (immunology), T-Lymphocytes (immunology), Vaccines (immunology).
- MESH :
- chemical , blood : Antibodies, Viral.
- immunology : Cross Reactions, Immune Sera, SARS Virus, Severe Acute Respiratory Syndrome, T-Lymphocytes, Vaccines.
- methods : Enzyme-Linked Immunosorbent Assay.
- Teeft :
- Ampv, Animals, Attenuated, Bacille, Beijing, Biological science, Bovine serum albumin, Cell proliferation, Child, Child, Preschool, Clinical analysis, Cona, Elisa, Encephalitis, Haemophilus influenzae type, Humans, Immune responses, Immunisation, Immunised, Immunised mice, Immunization, Inbred, Inbred mice, Individual vaccine, Infant, Japanese encephalitis vaccine, Kunming mice, Measles, Meningococcal polysaccharide, Mice, Mice immunised, Mice, Inbred C57BL, Mmrv, Mumps, Nixed1 nixed2, Optical density, Oral poliovirus vaccine, Other factors, Parainfluenza virus, Poliovirus, Polysaccharide, Positive control, Respiratory syndrome, Results show, Rubella, Rubella vaccine, Rubella virus, Sars, Second immunisation, Several vaccines, Specific antibodies, Streptococcus, Streptococcus pneumoniae vaccine, Syndrome, Tetanus, Third immunisation, Vaccine, Vero cells, Virus vaccine, Wang.
Abstract
In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.
Url:
DOI: 10.1136/jcp.2006.038893
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<term>Child</term>
<term>Child, Preschool</term>
<term>Cross Reactions (immunology)</term>
<term>Enzyme-Linked Immunosorbent Assay (methods)</term>
<term>Humans</term>
<term>Immune Sera (immunology)</term>
<term>Immunization</term>
<term>Infant</term>
<term>Mice</term>
<term>Mice, Inbred C57BL</term>
<term>SARS CoV, SARS coronavirus</term>
<term>SARS Virus (immunology)</term>
<term>SARS, severe acute respiratory syndrome</term>
<term>Severe Acute Respiratory Syndrome (immunology)</term>
<term>T-Lymphocytes (immunology)</term>
<term>Vaccines (immunology)</term>
</keywords>
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<term>Anticorps antiviraux (sang)</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Humains</term>
<term>Immunisation</term>
<term>Lymphocytes T (immunologie)</term>
<term>Nourrisson</term>
<term>Réactions croisées (immunologie)</term>
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<term>Souris de lignée C57BL</term>
<term>Syndrome respiratoire aigu sévère (immunologie)</term>
<term>Sérums immuns (immunologie)</term>
<term>Test ELISA ()</term>
<term>Vaccins (immunologie)</term>
<term>Virus du SRAS (immunologie)</term>
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<term>Réactions croisées</term>
<term>Syndrome respiratoire aigu sévère</term>
<term>Sérums immuns</term>
<term>Vaccins</term>
<term>Virus du SRAS</term>
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<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Cross Reactions</term>
<term>Immune Sera</term>
<term>SARS Virus</term>
<term>Severe Acute Respiratory Syndrome</term>
<term>T-Lymphocytes</term>
<term>Vaccines</term>
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<term>Respiratory syndrome</term>
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<front><div type="abstract" xml:lang="en">In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.</div>
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