Children’s vaccines do not induce cross reactivity against SARS-CoV
Identifieur interne : 000274 ( Istex/Corpus ); précédent : 000273; suivant : 000275Children’s vaccines do not induce cross reactivity against SARS-CoV
Auteurs : Yang Yu ; Huali Jin ; Ze Chen ; Qingling L. Yu ; Yijie J. Ma ; Xiaolin L. Sun ; Bin WangSource :
- Journal of Clinical Pathology [ 0021-9746 ] ; 2007-02.
English descriptors
- KwdEn :
- Teeft :
- Ampv, Attenuated, Bacille, Beijing, Biological science, Bovine serum albumin, Cell proliferation, Clinical analysis, Cona, Elisa, Encephalitis, Haemophilus influenzae type, Immune responses, Immunisation, Immunised, Immunised mice, Inbred, Inbred mice, Individual vaccine, Japanese encephalitis vaccine, Kunming mice, Measles, Meningococcal polysaccharide, Mice immunised, Mmrv, Mumps, Nixed1 nixed2, Optical density, Oral poliovirus vaccine, Other factors, Parainfluenza virus, Poliovirus, Polysaccharide, Positive control, Respiratory syndrome, Results show, Rubella, Rubella vaccine, Rubella virus, Sars, Second immunisation, Several vaccines, Specific antibodies, Streptococcus, Streptococcus pneumoniae vaccine, Syndrome, Tetanus, Third immunisation, Vaccine, Vero cells, Virus vaccine, Wang.
Abstract
In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.
Url:
DOI: 10.1136/jcp.2006.038893
Links to Exploration step
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<journal-title>Journal of Clinical Pathology</journal-title>
<abbrev-journal-title abbrev-type="publisher">J Clin Pathol</abbrev-journal-title>
<issn pub-type="ppub">0021-9746</issn>
<issn pub-type="epub">1472-4146</issn>
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<article-id pub-id-type="doi">10.1136/jcp.2006.038893</article-id>
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<title-group><article-title>Children’s vaccines do not induce cross reactivity against SARS-CoV</article-title>
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<contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Yu</surname>
<given-names>Yang</given-names>
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<contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Jin</surname>
<given-names>Huali</given-names>
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<contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Chen</surname>
<given-names>Ze</given-names>
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<contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Yu</surname>
<given-names>Qingling L</given-names>
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<contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Ma</surname>
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<contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Sun</surname>
<given-names>Xiaolin L</given-names>
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<contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Wang</surname>
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<aff id="AFF1"><label>1</label>
State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, China</aff>
<aff id="AFF2"><label>2</label>
Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China</aff>
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<author-notes><corresp>Correspondence to:
Dr B Wang
State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, 2 Yuanmingyuan Xi Road, Beijing 100094, China; <ext-link xlink:href="bwang3@cau.edu.cn" ext-link-type="email" xlink:type="simple">bwang3@cau.edu.cn</ext-link>
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<year>2007</year>
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<pub-date pub-type="epub"><day>30</day>
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<year>2007</year>
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<volume>60</volume>
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<fpage>208</fpage>
<history><date date-type="accepted"><day>06</day>
<month>06</month>
<year>2006</year>
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<abstract xml:lang="en"><p>In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.</p>
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<note type="author-notes">Correspondence to:
Dr B Wang
State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, 2 Yuanmingyuan Xi Road, Beijing 100094, China; bwang3@cau.edu.cn</note>
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