Children's vaccines do not induce cross reactivity against SARS-CoV.
Identifieur interne : 000086 ( Ncbi/Checkpoint ); précédent : 000085; suivant : 000087Children's vaccines do not induce cross reactivity against SARS-CoV.
Auteurs : Yang Yu [République populaire de Chine] ; Huali Jin ; Ze Chen ; Qingling L. Yu ; Yijie J. Ma ; Xiaolin L. Sun ; Bin WangSource :
- Journal of clinical pathology [ 0021-9746 ] ; 2007.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antiviraux (sang), Enfant, Enfant d'âge préscolaire, Humains, Immunisation, Lymphocytes T (immunologie), Nourrisson, Réactions croisées (immunologie), Souris, Souris de lignée C57BL, Syndrome respiratoire aigu sévère (immunologie), Sérums immuns (immunologie), Test ELISA (), Vaccins (immunologie), Virus du SRAS (immunologie).
- MESH :
English descriptors
- KwdEn :
- Animals, Antibodies, Viral (blood), Child, Child, Preschool, Cross Reactions (immunology), Enzyme-Linked Immunosorbent Assay (methods), Humans, Immune Sera (immunology), Immunization, Infant, Mice, Mice, Inbred C57BL, SARS Virus (immunology), Severe Acute Respiratory Syndrome (immunology), T-Lymphocytes (immunology), Vaccines (immunology).
- MESH :
- chemical , blood : Antibodies, Viral.
- immunology : Cross Reactions, Immune Sera, SARS Virus, Severe Acute Respiratory Syndrome, T-Lymphocytes, Vaccines.
- methods : Enzyme-Linked Immunosorbent Assay.
- Animals, Child, Child, Preschool, Humans, Immunization, Infant, Mice, Mice, Inbred C57BL.
Abstract
In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.
DOI: 10.1136/jcp.2006.038893
PubMed: 17264247
Affiliations:
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Yu</name></author><author><name sortKey="Ma, Yijie J" sort="Ma, Yijie J" uniqKey="Ma Y" first="Yijie J" last="Ma">Yijie J. Ma</name></author><author><name sortKey="Sun, Xiaolin L" sort="Sun, Xiaolin L" uniqKey="Sun X" first="Xiaolin L" last="Sun">Xiaolin L. 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Yu</name></author><author><name sortKey="Ma, Yijie J" sort="Ma, Yijie J" uniqKey="Ma Y" first="Yijie J" last="Ma">Yijie J. Ma</name></author><author><name sortKey="Sun, Xiaolin L" sort="Sun, Xiaolin L" uniqKey="Sun X" first="Xiaolin L" last="Sun">Xiaolin L. Sun</name></author><author><name sortKey="Wang, Bin" sort="Wang, Bin" uniqKey="Wang B" first="Bin" last="Wang">Bin Wang</name></author></analytic><series><title level="j">Journal of clinical pathology</title><idno type="ISSN">0021-9746</idno><imprint><date when="2007" type="published">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antibodies, Viral (blood)</term><term>Child</term><term>Child, Preschool</term><term>Cross Reactions (immunology)</term><term>Enzyme-Linked Immunosorbent Assay (methods)</term><term>Humans</term><term>Immune Sera (immunology)</term><term>Immunization</term><term>Infant</term><term>Mice</term><term>Mice, Inbred C57BL</term><term>SARS Virus (immunology)</term><term>Severe Acute Respiratory Syndrome (immunology)</term><term>T-Lymphocytes (immunology)</term><term>Vaccines (immunology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Anticorps antiviraux (sang)</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Humains</term><term>Immunisation</term><term>Lymphocytes T (immunologie)</term><term>Nourrisson</term><term>Réactions croisées (immunologie)</term><term>Souris</term><term>Souris de lignée C57BL</term><term>Syndrome respiratoire aigu sévère (immunologie)</term><term>Sérums immuns (immunologie)</term><term>Test ELISA ()</term><term>Vaccins (immunologie)</term><term>Virus du SRAS (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Viral</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Lymphocytes T</term><term>Réactions croisées</term><term>Syndrome respiratoire aigu sévère</term><term>Sérums immuns</term><term>Vaccins</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Cross Reactions</term><term>Immune Sera</term><term>SARS Virus</term><term>Severe Acute Respiratory Syndrome</term><term>T-Lymphocytes</term><term>Vaccines</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Enzyme-Linked Immunosorbent Assay</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antiviraux</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Child</term><term>Child, Preschool</term><term>Humans</term><term>Immunization</term><term>Infant</term><term>Mice</term><term>Mice, Inbred C57BL</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Humains</term><term>Immunisation</term><term>Nourrisson</term><term>Souris</term><term>Souris de lignée C57BL</term><term>Test ELISA</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><noCountry><name sortKey="Chen, Ze" sort="Chen, Ze" uniqKey="Chen Z" first="Ze" last="Chen">Ze Chen</name><name sortKey="Jin, Huali" sort="Jin, Huali" uniqKey="Jin H" first="Huali" last="Jin">Huali Jin</name><name sortKey="Ma, Yijie J" sort="Ma, Yijie J" uniqKey="Ma Y" first="Yijie J" last="Ma">Yijie J. Ma</name><name sortKey="Sun, Xiaolin L" sort="Sun, Xiaolin L" uniqKey="Sun X" first="Xiaolin L" last="Sun">Xiaolin L. Sun</name><name sortKey="Wang, Bin" sort="Wang, Bin" uniqKey="Wang B" first="Bin" last="Wang">Bin Wang</name><name sortKey="Yu, Qingling L" sort="Yu, Qingling L" uniqKey="Yu Q" first="Qingling L" last="Yu">Qingling L. Yu</name></noCountry><country name="République populaire de Chine"><noRegion><name sortKey="Yu, Yang" sort="Yu, Yang" uniqKey="Yu Y" first="Yang" last="Yu">Yang Yu</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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