Antiviral activity of interferon-based combination therapy in critically ill patients with COVID-19: Preliminary observations.
Identifieur interne : 000569 ( Main/Corpus ); précédent : 000568; suivant : 000570Antiviral activity of interferon-based combination therapy in critically ill patients with COVID-19: Preliminary observations.
Auteurs : Paolo Gaibani ; Tommaso Tonetti ; Michele Bartoletti ; Maria Carla Re ; Pierluigi Viale ; V Marco RanieriSource :
- Journal of global antimicrobial resistance [ 2213-7173 ] ; 2021.
English descriptors
- KwdEn :
- Antiviral Agents (therapeutic use), COVID-19 (drug therapy), COVID-19 (virology), Critical Illness (therapy), Drug Therapy, Combination (MeSH), Humans (MeSH), Hydroxychloroquine (therapeutic use), Interferon beta-1a (therapeutic use), Interferons (therapeutic use), Lopinavir (therapeutic use), Ritonavir (therapeutic use), SARS-CoV-2 (isolation & purification), Viral Load (drug effects).
- MESH :
- chemical , therapeutic use : Antiviral Agents, Hydroxychloroquine, Interferon beta-1a, Interferons, Lopinavir, Ritonavir.
- drug effects : Viral Load.
- drug therapy : COVID-19.
- isolation & purification : SARS-CoV-2.
- therapy : Critical Illness.
- virology : COVID-19.
- Drug Therapy, Combination, Humans.
DOI: 10.1016/j.jgar.2020.12.011
PubMed: 33385588
PubMed Central: PMC7833089
Links to Exploration step
pubmed:33385588Le document en format XML
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Orsola-Malpighi University Hospital, Bologna, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Tonetti, Tommaso" sort="Tonetti, Tommaso" uniqKey="Tonetti T" first="Tommaso" last="Tonetti">Tommaso Tonetti</name><affiliation><nlm:affiliation>Alma Mater Studiorum-Università di Bologna, Dipartimento di Scienze Mediche e Chirurgiche, Anesthesia and Intensive Care Medicine, IRCCS Policlinico di Sant'Orsola, Bologna, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Bartoletti, Michele" sort="Bartoletti, Michele" uniqKey="Bartoletti M" first="Michele" last="Bartoletti">Michele Bartoletti</name><affiliation><nlm:affiliation>Operative Unit of Infectious Diseases, IRCCS S. Orsola-Malpighi University Hospital, 9 via G. Massarenti, 40138 Bologna, Italy. Electronic address: m.bartoletti@unibo.it.</nlm:affiliation></affiliation></author><author><name sortKey="Re, Maria Carla" sort="Re, Maria Carla" uniqKey="Re M" first="Maria Carla" last="Re">Maria Carla Re</name><affiliation><nlm:affiliation>Operative Unit of Clinical Microbiology, IRCCS S. Orsola-Malpighi University Hospital, Bologna, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Viale, Pierluigi" sort="Viale, Pierluigi" uniqKey="Viale P" first="Pierluigi" last="Viale">Pierluigi Viale</name><affiliation><nlm:affiliation>Operative Unit of Infectious Diseases, IRCCS S. Orsola-Malpighi University Hospital, 9 via G. Massarenti, 40138 Bologna, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Ranieri, V Marco" sort="Ranieri, V Marco" uniqKey="Ranieri V" first="V Marco" last="Ranieri">V Marco Ranieri</name><affiliation><nlm:affiliation>Alma Mater Studiorum-Università di Bologna, Dipartimento di Scienze Mediche e Chirurgiche, Anesthesia and Intensive Care Medicine, IRCCS Policlinico di Sant'Orsola, Bologna, Italy.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2021">2021</date><idno type="RBID">pubmed:33385588</idno><idno type="pmid">33385588</idno><idno type="doi">10.1016/j.jgar.2020.12.011</idno><idno type="pmc">PMC7833089</idno><idno type="wicri:Area/Main/Corpus">000569</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000569</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Antiviral activity of interferon-based combination therapy in critically ill patients with COVID-19: Preliminary observations.</title><author><name sortKey="Gaibani, Paolo" sort="Gaibani, Paolo" uniqKey="Gaibani P" first="Paolo" last="Gaibani">Paolo Gaibani</name><affiliation><nlm:affiliation>Operative Unit of Clinical Microbiology, IRCCS S. Orsola-Malpighi University Hospital, Bologna, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Tonetti, Tommaso" sort="Tonetti, Tommaso" uniqKey="Tonetti T" first="Tommaso" last="Tonetti">Tommaso Tonetti</name><affiliation><nlm:affiliation>Alma Mater Studiorum-Università di Bologna, Dipartimento di Scienze Mediche e Chirurgiche, Anesthesia and Intensive Care Medicine, IRCCS Policlinico di Sant'Orsola, Bologna, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Bartoletti, Michele" sort="Bartoletti, Michele" uniqKey="Bartoletti M" first="Michele" last="Bartoletti">Michele Bartoletti</name><affiliation><nlm:affiliation>Operative Unit of Infectious Diseases, IRCCS S. Orsola-Malpighi University Hospital, 9 via G. Massarenti, 40138 Bologna, Italy. Electronic address: m.bartoletti@unibo.it.</nlm:affiliation></affiliation></author><author><name sortKey="Re, Maria Carla" sort="Re, Maria Carla" uniqKey="Re M" first="Maria Carla" last="Re">Maria Carla Re</name><affiliation><nlm:affiliation>Operative Unit of Clinical Microbiology, IRCCS S. Orsola-Malpighi University Hospital, Bologna, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Viale, Pierluigi" sort="Viale, Pierluigi" uniqKey="Viale P" first="Pierluigi" last="Viale">Pierluigi Viale</name><affiliation><nlm:affiliation>Operative Unit of Infectious Diseases, IRCCS S. Orsola-Malpighi University Hospital, 9 via G. Massarenti, 40138 Bologna, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Ranieri, V Marco" sort="Ranieri, V Marco" uniqKey="Ranieri V" first="V Marco" last="Ranieri">V Marco Ranieri</name><affiliation><nlm:affiliation>Alma Mater Studiorum-Università di Bologna, Dipartimento di Scienze Mediche e Chirurgiche, Anesthesia and Intensive Care Medicine, IRCCS Policlinico di Sant'Orsola, Bologna, Italy.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Journal of global antimicrobial resistance</title><idno type="eISSN">2213-7173</idno><imprint><date when="2021" type="published">2021</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antiviral Agents (therapeutic use)</term><term>COVID-19 (drug therapy)</term><term>COVID-19 (virology)</term><term>Critical Illness (therapy)</term><term>Drug Therapy, Combination (MeSH)</term><term>Humans (MeSH)</term><term>Hydroxychloroquine (therapeutic use)</term><term>Interferon beta-1a (therapeutic use)</term><term>Interferons (therapeutic use)</term><term>Lopinavir (therapeutic use)</term><term>Ritonavir (therapeutic use)</term><term>SARS-CoV-2 (isolation & purification)</term><term>Viral Load (drug effects)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term><term>Hydroxychloroquine</term><term>Interferon beta-1a</term><term>Interferons</term><term>Lopinavir</term><term>Ritonavir</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Viral Load</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>COVID-19</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>SARS-CoV-2</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Critical Illness</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>COVID-19</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Drug Therapy, Combination</term><term>Humans</term></keywords></textClass></profileDesc></teiHeader></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">33385588</PMID><DateCompleted><Year>2021</Year><Month>04</Month><Day>14</Day></DateCompleted><DateRevised><Year>2021</Year><Month>04</Month><Day>14</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2213-7173</ISSN><JournalIssue CitedMedium="Internet"><Volume>24</Volume><PubDate><Year>2021</Year><Month>03</Month></PubDate></JournalIssue><Title>Journal of global antimicrobial resistance</Title><ISOAbbreviation>J Glob Antimicrob Resist</ISOAbbreviation></Journal><ArticleTitle>Antiviral activity of interferon-based combination therapy in critically ill patients with COVID-19: Preliminary observations.</ArticleTitle><Pagination><MedlinePgn>124-126</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S2213-7165(20)30325-8</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jgar.2020.12.011</ELocationID><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gaibani</LastName><ForeName>Paolo</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Operative Unit of Clinical Microbiology, IRCCS S. 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Massarenti, 40138 Bologna, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ranieri</LastName><ForeName>V Marco</ForeName><Initials>VM</Initials><AffiliationInfo><Affiliation>Alma Mater Studiorum-Università di Bologna, Dipartimento di Scienze Mediche e Chirurgiche, Anesthesia and Intensive Care Medicine, IRCCS Policlinico di Sant'Orsola, Bologna, Italy.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016422">Letter</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>12</Month><Day>29</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>J Glob Antimicrob Resist</MedlineTA><NlmUniqueID>101622459</NlmUniqueID><ISSNLinking>2213-7165</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000998">Antiviral 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