Treatment of pulmonary hemorrhage in childhood systemic lupus erythematosus with mycophenolate mofetil.
Identifieur interne : 000461 ( PubMed/Curation ); précédent : 000460; suivant : 000462Treatment of pulmonary hemorrhage in childhood systemic lupus erythematosus with mycophenolate mofetil.
Auteurs : Ahmed S. Samad [États-Unis] ; Carol B. LindsleySource :
- Southern medical journal [ 0038-4348 ] ; 2003.
Descripteurs français
- KwdFr :
- Acide mycophénolique (analogues et dérivés), Acide mycophénolique (usage thérapeutique), Adolescent, Association de médicaments, Association thérapeutique, Glomérulonéphrite lupique (diagnostic), Glomérulonéphrite lupique (traitement médicamenteux), Humains, Hydroxychloroquine (usage thérapeutique), Hémorragie (diagnostic), Hémorragie (traitement médicamenteux), Immunosuppresseurs (usage thérapeutique), Lupus érythémateux disséminé (diagnostic), Lupus érythémateux disséminé (traitement médicamenteux), Maladies pulmonaires (diagnostic), Maladies pulmonaires (traitement médicamenteux), Mâle, Méthylprednisolone (usage thérapeutique), Perfusions veineuses, Plasmaphérèse, Prednisone (usage thérapeutique), Ventilation artificielle, Évolution de la maladie.
- MESH :
- analogues et dérivés : Acide mycophénolique.
- diagnostic : Glomérulonéphrite lupique, Hémorragie, Lupus érythémateux disséminé, Maladies pulmonaires.
- traitement médicamenteux : Glomérulonéphrite lupique, Hémorragie, Lupus érythémateux disséminé, Maladies pulmonaires.
- usage thérapeutique : Acide mycophénolique, Hydroxychloroquine, Immunosuppresseurs, Méthylprednisolone, Prednisone.
- Adolescent, Association de médicaments, Association thérapeutique, Humains, Mâle, Perfusions veineuses, Plasmaphérèse, Ventilation artificielle, Évolution de la maladie.
English descriptors
- KwdEn :
- Adolescent, Combined Modality Therapy, Disease Progression, Drug Therapy, Combination, Hemorrhage (diagnosis), Hemorrhage (drug therapy), Humans, Hydroxychloroquine (therapeutic use), Immunosuppressive Agents (therapeutic use), Infusions, Intravenous, Lung Diseases (diagnosis), Lung Diseases (drug therapy), Lupus Erythematosus, Systemic (diagnosis), Lupus Erythematosus, Systemic (drug therapy), Lupus Nephritis (diagnosis), Lupus Nephritis (drug therapy), Male, Methylprednisolone (therapeutic use), Mycophenolic Acid (analogs & derivatives), Mycophenolic Acid (therapeutic use), Plasmapheresis, Prednisone (therapeutic use), Respiration, Artificial.
- MESH :
- chemical , analogs & derivatives : Mycophenolic Acid.
- chemical , therapeutic use : Hydroxychloroquine, Immunosuppressive Agents, Methylprednisolone, Mycophenolic Acid, Prednisone.
- diagnosis : Hemorrhage, Lung Diseases, Lupus Erythematosus, Systemic, Lupus Nephritis.
- drug therapy : Hemorrhage, Lung Diseases, Lupus Erythematosus, Systemic, Lupus Nephritis.
- Adolescent, Combined Modality Therapy, Disease Progression, Drug Therapy, Combination, Humans, Infusions, Intravenous, Male, Plasmapheresis, Respiration, Artificial.
Abstract
Systemic lupus erythematosus is a chronic autoimmune disease of unknown etiology with multisystem involvement. Pulmonary hemorrhage is a major life-threatening manifestation in children and adolescents with systemic lupus erythematosus, as well as in adults. Treatment has traditionally been with high-dose corticosteroids, with or without the addition of cytotoxic agents. We report the response of a patient with childhood systemic lupus erythematosus with recurrent pulmonary hemorrhage to treatment with mycophenolate mofetil.
DOI: 10.1097/01.SMJ.0000054424.20202.7D
PubMed: 12940327
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Pulmonary hemorrhage is a major life-threatening manifestation in children and adolescents with systemic lupus erythematosus, as well as in adults. Treatment has traditionally been with high-dose corticosteroids, with or without the addition of cytotoxic agents. We report the response of a patient with childhood systemic lupus erythematosus with recurrent pulmonary hemorrhage to treatment with mycophenolate mofetil.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">12940327</PMID><DateCompleted><Year>2003</Year><Month>09</Month><Day>24</Day></DateCompleted><DateRevised><Year>2016</Year><Month>11</Month><Day>24</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0038-4348</ISSN><JournalIssue CitedMedium="Print"><Volume>96</Volume><Issue>7</Issue><PubDate><Year>2003</Year><Month>Jul</Month></PubDate></JournalIssue><Title>Southern medical journal</Title><ISOAbbreviation>South. Med. 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