Treatment of pulmonary hemorrhage in childhood systemic lupus erythematosus with mycophenolate mofetil.
Identifieur interne : 000461 ( PubMed/Corpus ); précédent : 000460; suivant : 000462Treatment of pulmonary hemorrhage in childhood systemic lupus erythematosus with mycophenolate mofetil.
Auteurs : Ahmed S. Samad ; Carol B. LindsleySource :
- Southern medical journal [ 0038-4348 ] ; 2003.
English descriptors
- KwdEn :
- Adolescent, Combined Modality Therapy, Disease Progression, Drug Therapy, Combination, Hemorrhage (diagnosis), Hemorrhage (drug therapy), Humans, Hydroxychloroquine (therapeutic use), Immunosuppressive Agents (therapeutic use), Infusions, Intravenous, Lung Diseases (diagnosis), Lung Diseases (drug therapy), Lupus Erythematosus, Systemic (diagnosis), Lupus Erythematosus, Systemic (drug therapy), Lupus Nephritis (diagnosis), Lupus Nephritis (drug therapy), Male, Methylprednisolone (therapeutic use), Mycophenolic Acid (analogs & derivatives), Mycophenolic Acid (therapeutic use), Plasmapheresis, Prednisone (therapeutic use), Respiration, Artificial.
- MESH :
- chemical , analogs & derivatives : Mycophenolic Acid.
- chemical , therapeutic use : Hydroxychloroquine, Immunosuppressive Agents, Methylprednisolone, Mycophenolic Acid, Prednisone.
- diagnosis : Hemorrhage, Lung Diseases, Lupus Erythematosus, Systemic, Lupus Nephritis.
- drug therapy : Hemorrhage, Lung Diseases, Lupus Erythematosus, Systemic, Lupus Nephritis.
- Adolescent, Combined Modality Therapy, Disease Progression, Drug Therapy, Combination, Humans, Infusions, Intravenous, Male, Plasmapheresis, Respiration, Artificial.
Abstract
Systemic lupus erythematosus is a chronic autoimmune disease of unknown etiology with multisystem involvement. Pulmonary hemorrhage is a major life-threatening manifestation in children and adolescents with systemic lupus erythematosus, as well as in adults. Treatment has traditionally been with high-dose corticosteroids, with or without the addition of cytotoxic agents. We report the response of a patient with childhood systemic lupus erythematosus with recurrent pulmonary hemorrhage to treatment with mycophenolate mofetil.
DOI: 10.1097/01.SMJ.0000054424.20202.7D
PubMed: 12940327
Links to Exploration step
pubmed:12940327Le document en format XML
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<author><name sortKey="Samad, Ahmed S" sort="Samad, Ahmed S" uniqKey="Samad A" first="Ahmed S" last="Samad">Ahmed S. Samad</name>
<affiliation><nlm:affiliation>Department of Pediatrics, University of Kansas Medical Center, Kansas City, Kansas 66160-7330, USA.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lindsley, Carol B" sort="Lindsley, Carol B" uniqKey="Lindsley C" first="Carol B" last="Lindsley">Carol B. Lindsley</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Treatment of pulmonary hemorrhage in childhood systemic lupus erythematosus with mycophenolate mofetil.</title>
<author><name sortKey="Samad, Ahmed S" sort="Samad, Ahmed S" uniqKey="Samad A" first="Ahmed S" last="Samad">Ahmed S. Samad</name>
<affiliation><nlm:affiliation>Department of Pediatrics, University of Kansas Medical Center, Kansas City, Kansas 66160-7330, USA.</nlm:affiliation>
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<author><name sortKey="Lindsley, Carol B" sort="Lindsley, Carol B" uniqKey="Lindsley C" first="Carol B" last="Lindsley">Carol B. Lindsley</name>
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<series><title level="j">Southern medical journal</title>
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<imprint><date when="2003" type="published">2003</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Combined Modality Therapy</term>
<term>Disease Progression</term>
<term>Drug Therapy, Combination</term>
<term>Hemorrhage (diagnosis)</term>
<term>Hemorrhage (drug therapy)</term>
<term>Humans</term>
<term>Hydroxychloroquine (therapeutic use)</term>
<term>Immunosuppressive Agents (therapeutic use)</term>
<term>Infusions, Intravenous</term>
<term>Lung Diseases (diagnosis)</term>
<term>Lung Diseases (drug therapy)</term>
<term>Lupus Erythematosus, Systemic (diagnosis)</term>
<term>Lupus Erythematosus, Systemic (drug therapy)</term>
<term>Lupus Nephritis (diagnosis)</term>
<term>Lupus Nephritis (drug therapy)</term>
<term>Male</term>
<term>Methylprednisolone (therapeutic use)</term>
<term>Mycophenolic Acid (analogs & derivatives)</term>
<term>Mycophenolic Acid (therapeutic use)</term>
<term>Plasmapheresis</term>
<term>Prednisone (therapeutic use)</term>
<term>Respiration, Artificial</term>
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<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Mycophenolic Acid</term>
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<term>Immunosuppressive Agents</term>
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<term>Mycophenolic Acid</term>
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<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Hemorrhage</term>
<term>Lung Diseases</term>
<term>Lupus Erythematosus, Systemic</term>
<term>Lupus Nephritis</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Hemorrhage</term>
<term>Lung Diseases</term>
<term>Lupus Erythematosus, Systemic</term>
<term>Lupus Nephritis</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Combined Modality Therapy</term>
<term>Disease Progression</term>
<term>Drug Therapy, Combination</term>
<term>Humans</term>
<term>Infusions, Intravenous</term>
<term>Male</term>
<term>Plasmapheresis</term>
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<front><div type="abstract" xml:lang="en">Systemic lupus erythematosus is a chronic autoimmune disease of unknown etiology with multisystem involvement. Pulmonary hemorrhage is a major life-threatening manifestation in children and adolescents with systemic lupus erythematosus, as well as in adults. Treatment has traditionally been with high-dose corticosteroids, with or without the addition of cytotoxic agents. We report the response of a patient with childhood systemic lupus erythematosus with recurrent pulmonary hemorrhage to treatment with mycophenolate mofetil.</div>
</front>
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<Day>24</Day>
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<DateRevised><Year>2016</Year>
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<Title>Southern medical journal</Title>
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<ArticleTitle>Treatment of pulmonary hemorrhage in childhood systemic lupus erythematosus with mycophenolate mofetil.</ArticleTitle>
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<Abstract><AbstractText>Systemic lupus erythematosus is a chronic autoimmune disease of unknown etiology with multisystem involvement. Pulmonary hemorrhage is a major life-threatening manifestation in children and adolescents with systemic lupus erythematosus, as well as in adults. Treatment has traditionally been with high-dose corticosteroids, with or without the addition of cytotoxic agents. We report the response of a patient with childhood systemic lupus erythematosus with recurrent pulmonary hemorrhage to treatment with mycophenolate mofetil.</AbstractText>
</Abstract>
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<ForeName>Ahmed S</ForeName>
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