ChloroquineV1, PascalFrancis, Checkpoint, bibRecord, 000033

Antiplasmodial Phenolic Compounds from Piptadenia pervillei

Identifieur interne : 000033 ( PascalFrancis/Checkpoint ); précédent : 000032; suivant : 000034

Antiplasmodial Phenolic Compounds from Piptadenia pervillei

Auteurs : Voahangy Ramanandraibe [Madagascar] ; Philippe Grellier [France] ; Marie-Thérèse Martin [France] ; Alexandre Deville [France] ; Roger Joyeau [France] ; David Ramanitrahasimbola [Madagascar] ; Elisabeth Mouray [France] ; Philippe Rasoanaivo [Madagascar] ; Lengo Mambu [France]

Source :

Planta medica [ 0032-0943 ] ; 2008.

RBID : Pascal:08-0207828

Descripteurs français

Pascal (Inist)
- Antipaludique, Leguminosae, Pharmacognosie, Plante médicinale, Origine végétale, Antiparasitaire, Catéchine gallate.
Wicri :
- topic : Plante médicinale.

English descriptors

KwdEn :
- Antimalarial, Leguminosae, Medicinal plant, Parasiticide, Pharmacognosy, Plant origin.

Abstract

Piptadenia pervillei Vatke (Fabaceae) was selected from a screening programme devoted to the search of naturally-occuring antimalarial compounds from plants of Madagascar. Bioassay-guided fractionation of the ethyl acetate extract of the leaves led to the isolation of four phenolic compounds, (+)-catechin (1), (+)-catechin 5-gallate (2), (+)-catechin 3-gallate (3) and ethyl gallate (4). Structures were determined by NMR and mass spectroscopy. Compounds 2 and 3 displayed the highest in vitro activity against the chloroquine-resistant strain FcBl of Plasmodium falciparum with IC_so values of 1.2 pM and 1.0 pM, respectively, and no significant cytotoxicity against the human embryonic lung cells MRC-5 was measured (IC₅₀ values >75μM). Five analogues (5-9) of (+)-catechin 5-gallate (2) were synthesized and evaluated for their antiplasmodial activity.

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000031
to stream PascalFrancis, to step Curation: 000035

Links to Exploration step

Pascal:08-0207828

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Antiplasmodial Phenolic Compounds from Piptadenia pervillei</title>
<author><name sortKey="Ramanandraibe, Voahangy" sort="Ramanandraibe, Voahangy" uniqKey="Ramanandraibe V" first="Voahangy" last="Ramanandraibe">Voahangy Ramanandraibe</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratoire de Bio-thérapeutique, Institut Malgache de Recherches Appliquées</s1>
<s2>Antananarivo</s2>
<s3>MDG</s3>
<sZ>1 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Madagascar</country>
<wicri:noRegion>Antananarivo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Grellier, Philippe" sort="Grellier, Philippe" uniqKey="Grellier P" first="Philippe" last="Grellier">Philippe Grellier</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>USM 0504 Biologie Fonctionnelle des Protozoaires, Département Régulations, Développement et Diversité Moléculaire, Muséum National d'Histoire Naturelle</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>2 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Martin, Marie Therese" sort="Martin, Marie Therese" uniqKey="Martin M" first="Marie-Thérèse" last="Martin">Marie-Thérèse Martin</name>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Institut de Chimie des Substances Naturelles, CNRS</s1>
<s2>Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region" nuts="2">Île-de-France</region>
<settlement type="city">Gif-sur-Yvette</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Deville, Alexandre" sort="Deville, Alexandre" uniqKey="Deville A" first="Alexandre" last="Deville">Alexandre Deville</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>USM 0502-UMR 5154 CNRS Chimie et Biochimie des Substances Naturelles, Département Régulations, Développement et Diversité Moléculaire, Muséum National d'Histoire Naturelle</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Joyeau, Roger" sort="Joyeau, Roger" uniqKey="Joyeau R" first="Roger" last="Joyeau">Roger Joyeau</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>USM 0502-UMR 5154 CNRS Chimie et Biochimie des Substances Naturelles, Département Régulations, Développement et Diversité Moléculaire, Muséum National d'Histoire Naturelle</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ramanitrahasimbola, David" sort="Ramanitrahasimbola, David" uniqKey="Ramanitrahasimbola D" first="David" last="Ramanitrahasimbola">David Ramanitrahasimbola</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratoire de Bio-thérapeutique, Institut Malgache de Recherches Appliquées</s1>
<s2>Antananarivo</s2>
<s3>MDG</s3>
<sZ>1 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Madagascar</country>
<wicri:noRegion>Antananarivo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mouray, Elisabeth" sort="Mouray, Elisabeth" uniqKey="Mouray E" first="Elisabeth" last="Mouray">Elisabeth Mouray</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>USM 0504 Biologie Fonctionnelle des Protozoaires, Département Régulations, Développement et Diversité Moléculaire, Muséum National d'Histoire Naturelle</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>2 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rasoanaivo, Philippe" sort="Rasoanaivo, Philippe" uniqKey="Rasoanaivo P" first="Philippe" last="Rasoanaivo">Philippe Rasoanaivo</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratoire de Bio-thérapeutique, Institut Malgache de Recherches Appliquées</s1>
<s2>Antananarivo</s2>
<s3>MDG</s3>
<sZ>1 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Madagascar</country>
<wicri:noRegion>Antananarivo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mambu, Lengo" sort="Mambu, Lengo" uniqKey="Mambu L" first="Lengo" last="Mambu">Lengo Mambu</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>USM 0502-UMR 5154 CNRS Chimie et Biochimie des Substances Naturelles, Département Régulations, Développement et Diversité Moléculaire, Muséum National d'Histoire Naturelle</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">08-0207828</idno>
<date when="2008">2008</date>
<idno type="stanalyst">PASCAL 08-0207828 INIST</idno>
<idno type="RBID">Pascal:08-0207828</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000031</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000035</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000033</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000033</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Antiplasmodial Phenolic Compounds from Piptadenia pervillei</title>
<author><name sortKey="Ramanandraibe, Voahangy" sort="Ramanandraibe, Voahangy" uniqKey="Ramanandraibe V" first="Voahangy" last="Ramanandraibe">Voahangy Ramanandraibe</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratoire de Bio-thérapeutique, Institut Malgache de Recherches Appliquées</s1>
<s2>Antananarivo</s2>
<s3>MDG</s3>
<sZ>1 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Madagascar</country>
<wicri:noRegion>Antananarivo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Grellier, Philippe" sort="Grellier, Philippe" uniqKey="Grellier P" first="Philippe" last="Grellier">Philippe Grellier</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>USM 0504 Biologie Fonctionnelle des Protozoaires, Département Régulations, Développement et Diversité Moléculaire, Muséum National d'Histoire Naturelle</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>2 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Martin, Marie Therese" sort="Martin, Marie Therese" uniqKey="Martin M" first="Marie-Thérèse" last="Martin">Marie-Thérèse Martin</name>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Institut de Chimie des Substances Naturelles, CNRS</s1>
<s2>Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region" nuts="2">Île-de-France</region>
<settlement type="city">Gif-sur-Yvette</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Deville, Alexandre" sort="Deville, Alexandre" uniqKey="Deville A" first="Alexandre" last="Deville">Alexandre Deville</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>USM 0502-UMR 5154 CNRS Chimie et Biochimie des Substances Naturelles, Département Régulations, Développement et Diversité Moléculaire, Muséum National d'Histoire Naturelle</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Joyeau, Roger" sort="Joyeau, Roger" uniqKey="Joyeau R" first="Roger" last="Joyeau">Roger Joyeau</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>USM 0502-UMR 5154 CNRS Chimie et Biochimie des Substances Naturelles, Département Régulations, Développement et Diversité Moléculaire, Muséum National d'Histoire Naturelle</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ramanitrahasimbola, David" sort="Ramanitrahasimbola, David" uniqKey="Ramanitrahasimbola D" first="David" last="Ramanitrahasimbola">David Ramanitrahasimbola</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratoire de Bio-thérapeutique, Institut Malgache de Recherches Appliquées</s1>
<s2>Antananarivo</s2>
<s3>MDG</s3>
<sZ>1 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Madagascar</country>
<wicri:noRegion>Antananarivo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mouray, Elisabeth" sort="Mouray, Elisabeth" uniqKey="Mouray E" first="Elisabeth" last="Mouray">Elisabeth Mouray</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>USM 0504 Biologie Fonctionnelle des Protozoaires, Département Régulations, Développement et Diversité Moléculaire, Muséum National d'Histoire Naturelle</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>2 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rasoanaivo, Philippe" sort="Rasoanaivo, Philippe" uniqKey="Rasoanaivo P" first="Philippe" last="Rasoanaivo">Philippe Rasoanaivo</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Laboratoire de Bio-thérapeutique, Institut Malgache de Recherches Appliquées</s1>
<s2>Antananarivo</s2>
<s3>MDG</s3>
<sZ>1 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Madagascar</country>
<wicri:noRegion>Antananarivo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mambu, Lengo" sort="Mambu, Lengo" uniqKey="Mambu L" first="Lengo" last="Mambu">Lengo Mambu</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>USM 0502-UMR 5154 CNRS Chimie et Biochimie des Substances Naturelles, Département Régulations, Développement et Diversité Moléculaire, Muséum National d'Histoire Naturelle</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Planta medica</title>
<title level="j" type="abbreviated">Planta med.</title>
<idno type="ISSN">0032-0943</idno>
<imprint><date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Planta medica</title>
<title level="j" type="abbreviated">Planta med.</title>
<idno type="ISSN">0032-0943</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antimalarial</term>
<term>Leguminosae</term>
<term>Medicinal plant</term>
<term>Parasiticide</term>
<term>Pharmacognosy</term>
<term>Plant origin</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Antipaludique</term>
<term>Leguminosae</term>
<term>Pharmacognosie</term>
<term>Plante médicinale</term>
<term>Origine végétale</term>
<term>Antiparasitaire</term>
<term>Catéchine gallate</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Plante médicinale</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Piptadenia pervillei Vatke (Fabaceae) was selected from a screening programme devoted to the search of naturally-occuring antimalarial compounds from plants of Madagascar. Bioassay-guided fractionation of the ethyl acetate extract of the leaves led to the isolation of four phenolic compounds, (+)-catechin (1), (+)-catechin 5-gallate (2), (+)-catechin 3-gallate (3) and ethyl gallate (4). Structures were determined by NMR and mass spectroscopy. Compounds 2 and 3 displayed the highest in vitro activity against the chloroquine-resistant strain FcBl of Plasmodium falciparum with IC<sub>so</sub>
 values of 1.2 pM and 1.0 pM, respectively, and no significant cytotoxicity against the human embryonic lung cells MRC-5 was measured (IC<sub>50</sub>
 values >75μM). Five analogues (5-9) of (+)-catechin 5-gallate (2) were synthesized and evaluated for their antiplasmodial activity.</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0032-0943</s0>
</fA01>
<fA02 i1="01"><s0>PLMEAA</s0>
</fA02>
<fA03 i2="1"><s0>Planta med.</s0>
</fA03>
<fA05><s2>74</s2>
</fA05>
<fA06><s2>4</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Antiplasmodial Phenolic Compounds from Piptadenia pervillei</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>RAMANANDRAIBE (Voahangy)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>GRELLIER (Philippe)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>MARTIN (Marie-Thérèse)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>DEVILLE (Alexandre)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>JOYEAU (Roger)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>RAMANITRAHASIMBOLA (David)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>MOURAY (Elisabeth)</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>RASOANAIVO (Philippe)</s1>
</fA11>
<fA11 i1="09" i2="1"><s1>MAMBU (Lengo)</s1>
</fA11>
<fA14 i1="01"><s1>Laboratoire de Bio-thérapeutique, Institut Malgache de Recherches Appliquées</s1>
<s2>Antananarivo</s2>
<s3>MDG</s3>
<sZ>1 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>USM 0504 Biologie Fonctionnelle des Protozoaires, Département Régulations, Développement et Diversité Moléculaire, Muséum National d'Histoire Naturelle</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>2 aut.</sZ>
<sZ>7 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Institut de Chimie des Substances Naturelles, CNRS</s1>
<s2>Gif-sur-Yvette</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
</fA14>
<fA14 i1="04"><s1>USM 0502-UMR 5154 CNRS Chimie et Biochimie des Substances Naturelles, Département Régulations, Développement et Diversité Moléculaire, Muséum National d'Histoire Naturelle</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>9 aut.</sZ>
</fA14>
<fA20><s1>417-421</s1>
</fA20>
<fA21><s1>2008</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>9624</s2>
<s5>354000183350430100</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2008 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>23 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>08-0207828</s0>
</fA47>
<fA60><s1>P</s1>
<s3>CR</s3>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Planta medica</s0>
</fA64>
<fA66 i1="01"><s0>DEU</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Piptadenia pervillei Vatke (Fabaceae) was selected from a screening programme devoted to the search of naturally-occuring antimalarial compounds from plants of Madagascar. Bioassay-guided fractionation of the ethyl acetate extract of the leaves led to the isolation of four phenolic compounds, (+)-catechin (1), (+)-catechin 5-gallate (2), (+)-catechin 3-gallate (3) and ethyl gallate (4). Structures were determined by NMR and mass spectroscopy. Compounds 2 and 3 displayed the highest in vitro activity against the chloroquine-resistant strain FcBl of Plasmodium falciparum with IC<sub>so</sub>
 values of 1.2 pM and 1.0 pM, respectively, and no significant cytotoxicity against the human embryonic lung cells MRC-5 was measured (IC<sub>50</sub>
 values >75μM). Five analogues (5-9) of (+)-catechin 5-gallate (2) were synthesized and evaluated for their antiplasmodial activity.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B02A04</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Antipaludique</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Antimalarial</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Antipalúdico</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Leguminosae</s0>
<s2>NS</s2>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Leguminosae</s0>
<s2>NS</s2>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Leguminosae</s0>
<s2>NS</s2>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Pharmacognosie</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Pharmacognosy</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Farmacognosia</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Plante médicinale</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Medicinal plant</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Planta medicinal</s0>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Origine végétale</s0>
<s5>23</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Plant origin</s0>
<s5>23</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Origen vegetal</s0>
<s5>23</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Antiparasitaire</s0>
<s5>24</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Parasiticide</s0>
<s5>24</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Antiparasitario</s0>
<s5>24</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Catéchine gallate</s0>
<s4>INC</s4>
<s5>86</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Dicotyledones</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Dicotyledones</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Dicotyledones</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Angiospermae</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Angiospermae</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Angiospermae</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Spermatophyta</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Spermatophyta</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Spermatophyta</s0>
<s2>NS</s2>
</fC07>
<fN21><s1>133</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
<affiliations><list><country><li>France</li>
<li>Madagascar</li>
</country>
<region><li>Île-de-France</li>
</region>
<settlement><li>Gif-sur-Yvette</li>
<li>Paris</li>
</settlement>
</list>
<tree><country name="Madagascar"><noRegion><name sortKey="Ramanandraibe, Voahangy" sort="Ramanandraibe, Voahangy" uniqKey="Ramanandraibe V" first="Voahangy" last="Ramanandraibe">Voahangy Ramanandraibe</name>
</noRegion>
<name sortKey="Ramanitrahasimbola, David" sort="Ramanitrahasimbola, David" uniqKey="Ramanitrahasimbola D" first="David" last="Ramanitrahasimbola">David Ramanitrahasimbola</name>
<name sortKey="Rasoanaivo, Philippe" sort="Rasoanaivo, Philippe" uniqKey="Rasoanaivo P" first="Philippe" last="Rasoanaivo">Philippe Rasoanaivo</name>
</country>
<country name="France"><region name="Île-de-France"><name sortKey="Grellier, Philippe" sort="Grellier, Philippe" uniqKey="Grellier P" first="Philippe" last="Grellier">Philippe Grellier</name>
</region>
<name sortKey="Deville, Alexandre" sort="Deville, Alexandre" uniqKey="Deville A" first="Alexandre" last="Deville">Alexandre Deville</name>
<name sortKey="Joyeau, Roger" sort="Joyeau, Roger" uniqKey="Joyeau R" first="Roger" last="Joyeau">Roger Joyeau</name>
<name sortKey="Mambu, Lengo" sort="Mambu, Lengo" uniqKey="Mambu L" first="Lengo" last="Mambu">Lengo Mambu</name>
<name sortKey="Martin, Marie Therese" sort="Martin, Marie Therese" uniqKey="Martin M" first="Marie-Thérèse" last="Martin">Marie-Thérèse Martin</name>
<name sortKey="Mouray, Elisabeth" sort="Mouray, Elisabeth" uniqKey="Mouray E" first="Elisabeth" last="Mouray">Elisabeth Mouray</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/PascalFrancis/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000033 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Checkpoint/biblio.hfd -nk 000033 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    ChloroquineV1
   |flux=    PascalFrancis
   |étape=   Checkpoint
   |type=    RBID
   |clé=     Pascal:08-0207828
   |texte=   Antiplasmodial Phenolic Compounds from Piptadenia pervillei
}}

This area was generated with Dilib version V0.6.33.
Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021

	Serveur d'exploration Chloroquine
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration Chloroquine

Antiplasmodial Phenolic Compounds from Piptadenia pervillei

Antiplasmodial Phenolic Compounds from Piptadenia pervillei

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri