《胸部恶性肿瘤围术期静脉血栓栓塞症预防中国专家共识(2018版)》解读之围术期高凝状态篇
Identifieur interne : 000253 ( Main/Exploration ); précédent : 000252; suivant : 000254《胸部恶性肿瘤围术期静脉血栓栓塞症预防中国专家共识(2018版)》解读之围术期高凝状态篇
Auteurs :Source :
- Chinese Journal of Lung Cancer [ 1009-3419 ] ; 2019.
Abstract
静脉血栓栓塞症(venous thromboembolism, VTE)是肺癌围术期常见的并发症,也是导致院内非预期死亡的重要原因。VTE临床相关的高危因素包括:患者自身的因素(高龄、肥胖等)、肿瘤相关因素(分型、分期等)、治疗相关因素(化疗、手术等)。除此之外,肿瘤细胞会表达癌性促凝因子(cancer procoagulant, CP)、组织因子(tissue factor, TF)、炎症因子等,或是激活血小板、炎性细胞等相关细胞,直接或间接地活化凝血过程,引起血液高凝状态,从而促进VTE的发生。同时,相关的生物标记物也可反映肺癌患者围术期的凝血状态,这有助于更准确地筛选VTE高危患者,更精准地予以预防策略。
Url:
DOI: 10.3779/j.issn.1009-3419.2019.12.03
PubMed: 31874669
PubMed Central: 6935033
Affiliations:
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<front><div type="abstract" xml:lang="en"><p>静脉血栓栓塞症(venous thromboembolism, VTE)是肺癌围术期常见的并发症,也是导致院内非预期死亡的重要原因。VTE临床相关的高危因素包括:患者自身的因素(高龄、肥胖等)、肿瘤相关因素(分型、分期等)、治疗相关因素(化疗、手术等)。除此之外,肿瘤细胞会表达癌性促凝因子(cancer procoagulant, CP)、组织因子(tissue factor, TF)、炎症因子等,或是激活血小板、炎性细胞等相关细胞,直接或间接地活化凝血过程,引起血液高凝状态,从而促进VTE的发生。同时,相关的生物标记物也可反映肺癌患者围术期的凝血状态,这有助于更准确地筛选VTE高危患者,更精准地予以预防策略。</p>
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