Relevance of 3D Cholangiography and Transient Elastography to Assess Cystic Fibrosis-Associated Liver Disease?
Identifieur interne : 000043 ( Main/Exploration ); précédent : 000042; suivant : 000044Relevance of 3D Cholangiography and Transient Elastography to Assess Cystic Fibrosis-Associated Liver Disease?
Auteurs : C. Lemaitre [France] ; S. Dominique [France] ; E. Billoud [France] ; M. Eliezer [France] ; H. Montialoux [France] ; M. Quillard [France] ; G. Riachi [France] ; E. Koning [France] ; H. Morisse-Pradier [France] ; G. Savoye [France] ; C. Savoye-Collet [France] ; O. Goria [France]Source :
- Canadian Respiratory Journal [ 1198-2241 ] ; 2016.
Abstract
Url:
DOI: 10.1155/2016/4592702
PubMed: 27445541
PubMed Central: 4939173
Affiliations:
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<author><name sortKey="Lemaitre, C" sort="Lemaitre, C" uniqKey="Lemaitre C" first="C." last="Lemaitre">C. Lemaitre</name>
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<author><name sortKey="Dominique, S" sort="Dominique, S" uniqKey="Dominique S" first="S." last="Dominique">S. Dominique</name>
<affiliation wicri:level="1"><nlm:aff id="I2">Department of Pneumology, Adult Cystic Fibrosis Centre, Rouen University Hospital, Rouen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Pneumology, Adult Cystic Fibrosis Centre, Rouen University Hospital, Rouen</wicri:regionArea>
<placeName><settlement type="city">Rouen</settlement>
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<author><name sortKey="Billoud, E" sort="Billoud, E" uniqKey="Billoud E" first="E." last="Billoud">E. Billoud</name>
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<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Gastroenterology, Le Havre General Hospital, Le Havre</wicri:regionArea>
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<author><name sortKey="Eliezer, M" sort="Eliezer, M" uniqKey="Eliezer M" first="M." last="Eliezer">M. Eliezer</name>
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<author><name sortKey="Montialoux, H" sort="Montialoux, H" uniqKey="Montialoux H" first="H." last="Montialoux">H. Montialoux</name>
<affiliation wicri:level="1"><nlm:aff id="I1">Department of Gastroenterology and Hepatology, Rouen University Hospital, Rouen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Gastroenterology and Hepatology, Rouen University Hospital, Rouen</wicri:regionArea>
<placeName><settlement type="city">Rouen</settlement>
</placeName>
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<author><name sortKey="Quillard, M" sort="Quillard, M" uniqKey="Quillard M" first="M." last="Quillard">M. Quillard</name>
<affiliation wicri:level="1"><nlm:aff id="I5">Clinical Biology Institute, Rouen University Hospital, Rouen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Clinical Biology Institute, Rouen University Hospital, Rouen</wicri:regionArea>
<placeName><settlement type="city">Rouen</settlement>
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<author><name sortKey="Riachi, G" sort="Riachi, G" uniqKey="Riachi G" first="G." last="Riachi">G. Riachi</name>
<affiliation wicri:level="1"><nlm:aff id="I1">Department of Gastroenterology and Hepatology, Rouen University Hospital, Rouen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Gastroenterology and Hepatology, Rouen University Hospital, Rouen</wicri:regionArea>
<placeName><settlement type="city">Rouen</settlement>
</placeName>
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<author><name sortKey="Koning, E" sort="Koning, E" uniqKey="Koning E" first="E." last="Koning">E. Koning</name>
<affiliation wicri:level="1"><nlm:aff id="I4">Department of Radiology, Rouen University Hospital, Rouen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Radiology, Rouen University Hospital, Rouen</wicri:regionArea>
<placeName><settlement type="city">Rouen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Morisse Pradier, H" sort="Morisse Pradier, H" uniqKey="Morisse Pradier H" first="H." last="Morisse-Pradier">H. Morisse-Pradier</name>
<affiliation wicri:level="1"><nlm:aff id="I2">Department of Pneumology, Adult Cystic Fibrosis Centre, Rouen University Hospital, Rouen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Pneumology, Adult Cystic Fibrosis Centre, Rouen University Hospital, Rouen</wicri:regionArea>
<placeName><settlement type="city">Rouen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Savoye, G" sort="Savoye, G" uniqKey="Savoye G" first="G." last="Savoye">G. Savoye</name>
<affiliation wicri:level="1"><nlm:aff id="I1">Department of Gastroenterology and Hepatology, Rouen University Hospital, Rouen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Gastroenterology and Hepatology, Rouen University Hospital, Rouen</wicri:regionArea>
<placeName><settlement type="city">Rouen</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="I6">INSERM U1073, Institute for Research and Innovation in Biomedicine, Faculty of Medicine, University of Rouen, Rouen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U1073, Institute for Research and Innovation in Biomedicine, Faculty of Medicine, University of Rouen, Rouen</wicri:regionArea>
<placeName><settlement type="city">Rouen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Savoye Collet, C" sort="Savoye Collet, C" uniqKey="Savoye Collet C" first="C." last="Savoye-Collet">C. Savoye-Collet</name>
<affiliation wicri:level="1"><nlm:aff id="I4">Department of Radiology, Rouen University Hospital, Rouen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Radiology, Rouen University Hospital, Rouen</wicri:regionArea>
<placeName><settlement type="city">Rouen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Goria, O" sort="Goria, O" uniqKey="Goria O" first="O." last="Goria">O. Goria</name>
<affiliation wicri:level="1"><nlm:aff id="I1">Department of Gastroenterology and Hepatology, Rouen University Hospital, Rouen, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Gastroenterology and Hepatology, Rouen University Hospital, Rouen</wicri:regionArea>
<placeName><settlement type="city">Rouen</settlement>
</placeName>
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</analytic>
<series><title level="j">Canadian Respiratory Journal</title>
<idno type="ISSN">1198-2241</idno>
<idno type="eISSN">1916-7245</idno>
<imprint><date when="2016">2016</date>
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<front><div type="abstract" xml:lang="en"><p><italic>Background.</italic>
Cystic fibrosis-associated liver disease (CFLD) is a major cause of death. The objective of our retrospective study was to describe the relevance of magnetic resonance imaging (MRI) and liver stiffness measurement (LSM) for CFLD evaluation.<italic> Methods.</italic>
All cystic fibrosis adult patients evaluated by MRI and LSM were included. MR signs of portal hypertension (PHT), dysmorphia, or cholangitis were collected and LSM expressed in kPa and Metavir.<italic> Results.</italic>
Of 25 patients, 52% had abnormal MRI. Median LSM was 5.7 kPa (3.4–9.9). Three patients had F2 score and one had F3 score. In patients with PHT, LSM was 7.85 kPa (3.7–9.9) compared to 5 (3.4–7.5) in others, <italic>p</italic>
= 0.02. In patients with abnormal liver function tests, 50% had increased LSM (≥F2), whereas 94% with normal tests had normal LSM (<italic>p</italic>
= 0.04). Seven patients had abnormal MRI despite normal ultrasonography.<italic> Conclusions.</italic>
MRI and LSM provide useful information on CFLD and may help to screen patients with PHT.</p>
</div>
</front>
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</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>France</li>
</country>
<settlement><li>Le Havre</li>
<li>Rouen</li>
</settlement>
</list>
<tree><country name="France"><noRegion><name sortKey="Lemaitre, C" sort="Lemaitre, C" uniqKey="Lemaitre C" first="C." last="Lemaitre">C. Lemaitre</name>
</noRegion>
<name sortKey="Billoud, E" sort="Billoud, E" uniqKey="Billoud E" first="E." last="Billoud">E. Billoud</name>
<name sortKey="Dominique, S" sort="Dominique, S" uniqKey="Dominique S" first="S." last="Dominique">S. Dominique</name>
<name sortKey="Eliezer, M" sort="Eliezer, M" uniqKey="Eliezer M" first="M." last="Eliezer">M. Eliezer</name>
<name sortKey="Goria, O" sort="Goria, O" uniqKey="Goria O" first="O." last="Goria">O. Goria</name>
<name sortKey="Koning, E" sort="Koning, E" uniqKey="Koning E" first="E." last="Koning">E. Koning</name>
<name sortKey="Montialoux, H" sort="Montialoux, H" uniqKey="Montialoux H" first="H." last="Montialoux">H. Montialoux</name>
<name sortKey="Morisse Pradier, H" sort="Morisse Pradier, H" uniqKey="Morisse Pradier H" first="H." last="Morisse-Pradier">H. Morisse-Pradier</name>
<name sortKey="Quillard, M" sort="Quillard, M" uniqKey="Quillard M" first="M." last="Quillard">M. Quillard</name>
<name sortKey="Riachi, G" sort="Riachi, G" uniqKey="Riachi G" first="G." last="Riachi">G. Riachi</name>
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</country>
</tree>
</affiliations>
</record>
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