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Effect of fenfluramine on episodic ACTH and cortisol secretion.

Identifieur interne : 000B17 ( Ncbi/Checkpoint ); précédent : 000B16; suivant : 000B18

Effect of fenfluramine on episodic ACTH and cortisol secretion.

Auteurs : T H Schürmeyer [Allemagne] ; G. Brademann ; A. Von Zur Mühlen

Source :

RBID : pubmed:8796137

English descriptors

Abstract

The central serotoninergic system is known to modulate the activity of the hypothalamic-pituitary-adrenal axis, but the effect of fenfluramine, a serotonin reuptake inhibitor, on ACTH and cortisol secretion is not well understood. We have therefore evaluated its effects on the hypothalamic-pituitary-adrenal axis in healthy controls.

PubMed: 8796137


Affiliations:


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pubmed:8796137

Le document en format XML

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<name sortKey="Schurmeyer, T H" sort="Schurmeyer, T H" uniqKey="Schurmeyer T" first="T H" last="Schürmeyer">T H Schürmeyer</name>
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<nlm:affiliation>Department of Endocrinology and Metabolism, The University, Trier, FR Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Endocrinology and Metabolism, The University, Trier</wicri:regionArea>
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<wicri:noRegion>Trier</wicri:noRegion>
<wicri:noRegion>Trier</wicri:noRegion>
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<name sortKey="Brademann, G" sort="Brademann, G" uniqKey="Brademann G" first="G" last="Brademann">G. Brademann</name>
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<name sortKey="Von Zur Muhlen, A" sort="Von Zur Muhlen, A" uniqKey="Von Zur Muhlen A" first="A" last="Von Zur Mühlen">A. Von Zur Mühlen</name>
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<term>Adrenocorticotropic Hormone (secretion)</term>
<term>Adult</term>
<term>Corticotropin-Releasing Hormone</term>
<term>Data Interpretation, Statistical</term>
<term>Fenfluramine (blood)</term>
<term>Fenfluramine (pharmacology)</term>
<term>Humans</term>
<term>Hydrocortisone (blood)</term>
<term>Hydrocortisone (secretion)</term>
<term>Hypothalamo-Hypophyseal System (drug effects)</term>
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<term>Pituitary-Adrenal System (drug effects)</term>
<term>Pituitary-Adrenal System (secretion)</term>
<term>Serotonin Uptake Inhibitors (blood)</term>
<term>Serotonin Uptake Inhibitors (pharmacology)</term>
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<term>Adrenocorticotropic Hormone</term>
<term>Fenfluramine</term>
<term>Hydrocortisone</term>
<term>Serotonin Uptake Inhibitors</term>
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<term>Fenfluramine</term>
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<term>Adrenocorticotropic Hormone</term>
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