Allostatic Load, Perceived Stress, and Health: A Prospective Study in Two Age Groups
Identifieur interne : 001944 ( Main/Exploration ); précédent : 001943; suivant : 001945Allostatic Load, Perceived Stress, and Health: A Prospective Study in Two Age Groups
Auteurs : J. Hellhammer [Allemagne] ; W. Schlotz [Allemagne] ; A A Stone [États-Unis] ; K M Pirke [Allemagne] ; D. Hellhammer [Allemagne]Source :
- Annals of the New York Academy of Sciences [ 0077-8923 ] ; 2004-12.
English descriptors
- KwdEn :
- Adult, Aged, Aging (physiology), Depression (epidemiology), Depression (psychology), Female, Fibrinogen (metabolism), Health, Humans, Hydrocortisone (deficiency), Hydrocortisone (metabolism), Hypothalamo-Hypophyseal System (physiology), Male, Pituitary-Adrenal System (physiology), Saliva (metabolism), Seasons, Stress, Psychological (complications), Stress, Psychological (physiopathology), WHR, allostatic load, chronic stress, cortisol, fibrinogen, health, hypocortisolism, protective and damaging effects.
- MESH :
- chemical , deficiency : Hydrocortisone.
- chemical , metabolism : Fibrinogen, Hydrocortisone.
- complications : Stress, Psychological.
- epidemiology : Depression.
- metabolism : Saliva.
- physiology : Aging, Hypothalamo-Hypophyseal System, Pituitary-Adrenal System.
- physiopathology : Stress, Psychological.
- psychology : Depression.
- Adult, Aged, Female, Health, Humans, Male, Seasons.
Abstract
Abstract: Overactivity of the hypothalamus‐pituitary‐adrenal axis (HPAA) has been observed in the presence of acute stress and, under chronic conditions, in disorders such as depression and anorexia nervosa as well as in cardiovascular and metabolic disorders. However, there may be other stress‐related disorders (fatigue, pain, etc) that seem to be associated with mild hypocortisolism. This suggests that two major subtypes of the HPAA response to stress need to be discriminated. In this study, we investigated 76 subjects with and without hypocortisolism, respectively, over a 1‐year period. Surprisingly, hypocortisolemic subjects had a lower allostatic load but they scored higher on measures of depression, perceived stress, and physical complaints. We propose a protective role of the hypocortisolemic stress response on cardiovascular and metabolic disorders, particularly in the elderly.
Url:
DOI: 10.1196/annals.1314.002
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000738
- to stream Istex, to step Curation: 000692
- to stream Istex, to step Checkpoint: 000A14
- to stream PubMed, to step Corpus: 000727
- to stream PubMed, to step Curation: 000727
- to stream PubMed, to step Checkpoint: 000727
- to stream Ncbi, to step Merge: 000184
- to stream Ncbi, to step Curation: 000184
- to stream Ncbi, to step Checkpoint: 000184
- to stream Main, to step Merge: 001B35
- to stream Main, to step Curation: 001944
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Allostatic Load, Perceived Stress, and Health: A Prospective Study in Two Age Groups</title>
<author><name sortKey="Hellhammer, J" sort="Hellhammer, J" uniqKey="Hellhammer J" first="J" last="Hellhammer">J. Hellhammer</name>
</author>
<author><name sortKey="Schlotz, W" sort="Schlotz, W" uniqKey="Schlotz W" first="W" last="Schlotz">W. Schlotz</name>
</author>
<author><name sortKey="Stone, A A" sort="Stone, A A" uniqKey="Stone A" first="A A" last="Stone">A A Stone</name>
</author>
<author><name sortKey="Pirke, K M" sort="Pirke, K M" uniqKey="Pirke K" first="K M" last="Pirke">K M Pirke</name>
</author>
<author><name sortKey="Hellhammer, D" sort="Hellhammer, D" uniqKey="Hellhammer D" first="D" last="Hellhammer">D. Hellhammer</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:266ED5AB7FDD7E7DA8533AB71BB8AA2599AFCD04</idno>
<date when="2004" year="2004">2004</date>
<idno type="doi">10.1196/annals.1314.002</idno>
<idno type="url">https://api.istex.fr/document/266ED5AB7FDD7E7DA8533AB71BB8AA2599AFCD04/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000738</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000738</idno>
<idno type="wicri:Area/Istex/Curation">000692</idno>
<idno type="wicri:Area/Istex/Checkpoint">000A14</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000A14</idno>
<idno type="wicri:doubleKey">0077-8923:2004:Hellhammer J:allostatic:load:perceived</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:15677392</idno>
<idno type="wicri:Area/PubMed/Corpus">000727</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000727</idno>
<idno type="wicri:Area/PubMed/Curation">000727</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000727</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000727</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000727</idno>
<idno type="wicri:Area/Ncbi/Merge">000184</idno>
<idno type="wicri:Area/Ncbi/Curation">000184</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000184</idno>
<idno type="wicri:doubleKey">0077-8923:2004:Hellhammer J:allostatic:load:perceived</idno>
<idno type="wicri:Area/Main/Merge">001B35</idno>
<idno type="wicri:Area/Main/Curation">001944</idno>
<idno type="wicri:Area/Main/Exploration">001944</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Allostatic Load, Perceived Stress, and Health: A Prospective Study in Two Age Groups</title>
<author><name sortKey="Hellhammer, J" sort="Hellhammer, J" uniqKey="Hellhammer J" first="J" last="Hellhammer">J. Hellhammer</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychobiology, Trier University, D‐54290 Trier</wicri:regionArea>
<wicri:noRegion>54290 Trier</wicri:noRegion>
<wicri:noRegion>D‐54290 Trier</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><country wicri:rule="url">Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Schlotz, W" sort="Schlotz, W" uniqKey="Schlotz W" first="W" last="Schlotz">W. Schlotz</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychobiology, Trier University, D‐54290 Trier</wicri:regionArea>
<wicri:noRegion>54290 Trier</wicri:noRegion>
<wicri:noRegion>D‐54290 Trier</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stone, A A" sort="Stone, A A" uniqKey="Stone A" first="A A" last="Stone">A A Stone</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, SUNY, Stony Brook, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pirke, K M" sort="Pirke, K M" uniqKey="Pirke K" first="K M" last="Pirke">K M Pirke</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychobiology, Trier University, D‐54290 Trier</wicri:regionArea>
<wicri:noRegion>54290 Trier</wicri:noRegion>
<wicri:noRegion>D‐54290 Trier</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hellhammer, D" sort="Hellhammer, D" uniqKey="Hellhammer D" first="D" last="Hellhammer">D. Hellhammer</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychobiology, Trier University, D‐54290 Trier</wicri:regionArea>
<wicri:noRegion>54290 Trier</wicri:noRegion>
<wicri:noRegion>D‐54290 Trier</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Annals of the New York Academy of Sciences</title>
<idno type="ISSN">0077-8923</idno>
<idno type="eISSN">1749-6632</idno>
<imprint><publisher>Blackwell Publishing Ltd</publisher>
<pubPlace>Oxford, UK</pubPlace>
<date type="published" when="2004-12">2004-12</date>
<biblScope unit="volume">1032</biblScope>
<biblScope unit="issue">1</biblScope>
<biblScope unit="page" from="8">8</biblScope>
<biblScope unit="page" to="13">13</biblScope>
</imprint>
<idno type="ISSN">0077-8923</idno>
</series>
<idno type="istex">266ED5AB7FDD7E7DA8533AB71BB8AA2599AFCD04</idno>
<idno type="DOI">10.1196/annals.1314.002</idno>
<idno type="ArticleID">NYAS8</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0077-8923</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aging (physiology)</term>
<term>Depression (epidemiology)</term>
<term>Depression (psychology)</term>
<term>Female</term>
<term>Fibrinogen (metabolism)</term>
<term>Health</term>
<term>Humans</term>
<term>Hydrocortisone (deficiency)</term>
<term>Hydrocortisone (metabolism)</term>
<term>Hypothalamo-Hypophyseal System (physiology)</term>
<term>Male</term>
<term>Pituitary-Adrenal System (physiology)</term>
<term>Saliva (metabolism)</term>
<term>Seasons</term>
<term>Stress, Psychological (complications)</term>
<term>Stress, Psychological (physiopathology)</term>
<term>WHR</term>
<term>allostatic load</term>
<term>chronic stress</term>
<term>cortisol</term>
<term>fibrinogen</term>
<term>health</term>
<term>hypocortisolism</term>
<term>protective and damaging effects</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="deficiency" xml:lang="en"><term>Hydrocortisone</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Fibrinogen</term>
<term>Hydrocortisone</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Stress, Psychological</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Depression</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Saliva</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Aging</term>
<term>Hypothalamo-Hypophyseal System</term>
<term>Pituitary-Adrenal System</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Stress, Psychological</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Depression</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Female</term>
<term>Health</term>
<term>Humans</term>
<term>Male</term>
<term>Seasons</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract">Abstract: Overactivity of the hypothalamus‐pituitary‐adrenal axis (HPAA) has been observed in the presence of acute stress and, under chronic conditions, in disorders such as depression and anorexia nervosa as well as in cardiovascular and metabolic disorders. However, there may be other stress‐related disorders (fatigue, pain, etc) that seem to be associated with mild hypocortisolism. This suggests that two major subtypes of the HPAA response to stress need to be discriminated. In this study, we investigated 76 subjects with and without hypocortisolism, respectively, over a 1‐year period. Surprisingly, hypocortisolemic subjects had a lower allostatic load but they scored higher on measures of depression, perceived stress, and physical complaints. We propose a protective role of the hypocortisolemic stress response on cardiovascular and metabolic disorders, particularly in the elderly.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>États-Unis</li>
</country>
<region><li>État de New York</li>
</region>
</list>
<tree><country name="Allemagne"><noRegion><name sortKey="Hellhammer, J" sort="Hellhammer, J" uniqKey="Hellhammer J" first="J" last="Hellhammer">J. Hellhammer</name>
</noRegion>
<name sortKey="Hellhammer, D" sort="Hellhammer, D" uniqKey="Hellhammer D" first="D" last="Hellhammer">D. Hellhammer</name>
<name sortKey="Hellhammer, J" sort="Hellhammer, J" uniqKey="Hellhammer J" first="J" last="Hellhammer">J. Hellhammer</name>
<name sortKey="Pirke, K M" sort="Pirke, K M" uniqKey="Pirke K" first="K M" last="Pirke">K M Pirke</name>
<name sortKey="Schlotz, W" sort="Schlotz, W" uniqKey="Schlotz W" first="W" last="Schlotz">W. Schlotz</name>
</country>
<country name="États-Unis"><region name="État de New York"><name sortKey="Stone, A A" sort="Stone, A A" uniqKey="Stone A" first="A A" last="Stone">A A Stone</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Rhénanie/explor/UnivTrevesV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001944 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001944 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Rhénanie |area= UnivTrevesV1 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:266ED5AB7FDD7E7DA8533AB71BB8AA2599AFCD04 |texte= Allostatic Load, Perceived Stress, and Health: A Prospective Study in Two Age Groups }}
![]() | This area was generated with Dilib version V0.6.31. | ![]() |