| Ident. | Authors (with country if any) | Title |
|---|
| 000411 (2019) |
Denise Rageot [Suisse] ; Thomas Bohnacker [Suisse] ; Erhan Keles [Suisse] ; Jacob A. Mcphail [Canada] ; Reece M. Hoffmann [Canada] ; Anna Melone [Suisse] ; Chiara Borsari [Suisse] ; Rohitha Sriramaratnam [Suisse] ; Alexander M. Sele [Suisse] ; Florent Beaufils [Suisse] ; Paul Hebeisen [Suisse] ; Doriano Fabbro [Suisse] ; Petra Hillmann [Suisse] ; John E. Burke [Canada] ; Matthias P. Wymann [Suisse] | (S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine (PQR530), a Potent, Orally Bioavailable, and Brain-Penetrable Dual Inhibitor of Class I PI3K and mTOR Kinase. |
| 000438 (2018) |
Jun-Ichi Inaba [États-Unis] ; Peter D. Nagy [États-Unis] | Tombusvirus RNA replication depends on the TOR pathway in yeast and plants. |
| 000441 (2018) |
Fatemeh Khadir [Iran, Canada] ; Christopher R. Shaler [Canada] ; Ahmad Oryan [Iran] ; Patrick T. Rudak [Canada] ; Delfina M. Mazzuca [Canada] ; Tahereh Taheri [Iran] ; Jimmy D. Dikeakos [Canada] ; S M Mansour Haeryfar [Canada] ; Sima Rafati [Iran] | Therapeutic control of leishmaniasis by inhibitors of the mammalian target of rapamycin. |
| 000489 (2018) |
Sebastian Zi Ba [Pologne] ; Artur Kowalik [Pologne] ; Kamil Zalewski [Pologne] ; Natalia Rusetska [Pologne] ; Krzysztof Goryca [Pologne] ; Agata Pia Cik [Pologne] ; Marcin Misiek [Pologne] ; Elwira Bakuła-Zalewska [Pologne] ; Janusz Kopczy Ski [Pologne] ; Kamil Kowalski [Pologne] ; Jakub Radziszewski [Pologne] ; Mariusz Bidzi Ski [Pologne] ; Stanisław G D [Pologne] ; Magdalena Kowalewska [Pologne] | Somatic mutation profiling of vulvar cancer: Exploring therapeutic targets. |
| 000500 (2018) |
Kunlun Xiang [République populaire de Chine] ; Bin Wang [République populaire de Chine] | Role of the PI3K‑AKT‑mTOR pathway in hepatitis B virus infection and replication. |
| 000645 (2018) |
Min Hee Kim [Corée du Sud] ; Joo-Won Park [Corée du Sud] ; Eun-Ji Lee [Corée du Sud] ; Shin Kim [Corée du Sud] ; Sun-Hye Shin [Corée du Sud] ; Jung-Hyuck Ahn [Corée du Sud] ; Yunjae Jung [Corée du Sud] ; Inkeun Park [Corée du Sud] ; Woo-Jae Park [Corée du Sud] | C16‑ceramide and sphingosine 1‑phosphate/S1PR2 have opposite effects on cell growth through mTOR signaling pathway regulation. |
| 000915 (2017) |
Hai-Chang Yin [République populaire de Chine] ; Li-Li Zhao [République populaire de Chine] ; Si-Qi Li [République populaire de Chine] ; Yin-Jie Niu [République populaire de Chine] ; Xin-Jie Jiang [République populaire de Chine] ; Li-Jing Xu [République populaire de Chine] ; Tao-Feng Lu [République populaire de Chine] ; Ling-Xia Han [République populaire de Chine] ; Sheng-Wang Liu [République populaire de Chine] ; Hong-Yan Chen [République populaire de Chine] | Autophagy activated by duck enteritis virus infection positively affects its replication. |
| 000A30 (2016) |
Chun-Yuan Li [Taïwan] ; Yi-Jan Wang [Taïwan] ; Shiao-Wei Huang [Taïwan] ; Cheng-Shun Cheng [Taïwan] ; Han-Ching Wang [Taïwan] | Replication of the Shrimp Virus WSSV Depends on Glutamate-Driven Anaplerosis. |
| 000B43 (2016) |
Longjun Guo [République populaire de Chine] ; Haidong Yu [République populaire de Chine] ; Weihong Gu [République populaire de Chine] ; Xiaolei Luo [République populaire de Chine] ; Ren Li [République populaire de Chine] ; Jian Zhang [République populaire de Chine] ; Yunfei Xu [République populaire de Chine] ; Lijun Yang [République populaire de Chine] ; Nan Shen [République populaire de Chine] ; Li Feng [République populaire de Chine] ; Yue Wang [République populaire de Chine] | Autophagy Negatively Regulates Transmissible Gastroenteritis Virus Replication. |
| 000E58 (2014) |
Michelle E. Doscas [États-Unis] ; Ashley J. Williamson [États-Unis] ; Lydia Usha [États-Unis] ; Yedida Bogachkov [États-Unis] ; Geetha S. Rao [États-Unis] ; Fei Xiao [États-Unis] ; Yimin Wang [États-Unis] ; Carl Ruby [États-Unis] ; Howard Kaufman [États-Unis] ; Jingsong Zhou [États-Unis] ; James W. Williams [États-Unis] ; Yi Li [États-Unis] ; Xiulong Xu [États-Unis] | Inhibition of p70 S6 kinase (S6K1) activity by A77 1726 and its effect on cell proliferation and cell cycle progress. |
| 001072 (2013) |
Xin Li [République populaire de Chine] ; Juan Zhang ; Zhiheng Chen ; Li Yang ; Xiaowei Xing ; Xing Ma ; Zuocheng Yang | Both PI3K- and mTOR-signaling pathways take part in CVB3-induced apoptosis of Hela cells. |
| 001263 (2011) |
Vidyarani Mohankumar [États-Unis] ; Nisha R. Dhanushkodi ; Ramaswamy Raju | Sindbis virus replication, is insensitive to rapamycin and torin1, and suppresses Akt/mTOR pathway late during infection in HEK cells. |
| 001437 (2010) |
Stephen L. Abrams [États-Unis] ; Linda S. Steelman ; John G. Shelton ; William Chappell ; Jörg B Secke ; Franca Stivala ; Marco Donia ; Ferdinando Nicoletti ; Massimo Libra ; Alberto M. Martelli ; James A. Mccubrey | Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy. |
| 001534 (2009) |
Gal Almogy [États-Unis] ; Garry P. Nolan | Conditional protein stabilization via the small molecules Shld-1 and rapamycin increases the signal-to-noise ratio with tet-inducible gene expression. |
| 001716 (2007) |
Takayuki Ikezoe [Japon] ; Chie Nishioka ; Kentaro Bandobashi ; Yang Yang ; Yoshio Kuwayama ; Yoshihiro Adachi ; Tamotsu Takeuchi ; H Phillip Koeffler ; Hirokuni Taguchi | Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells. |
| 001803 (2006) |
Jing Fang [États-Unis] ; Qiao Meng ; Peter K. Vogt ; Ruiwen Zhang ; Bing-Hua Jiang | A downstream kinase of the mammalian target of rapamycin, p70S6K1, regulates human double minute 2 protein phosphorylation and stability. |
| 001853 (2005) |
Shigeru Kanda [Japon] ; Yasuyoshi Miyata ; Yasushi Mochizuki ; Toshifumi Matsuyama ; Hiroshi Kanetake | Angiopoietin 1 is mitogenic for cultured endothelial cells. |
| 001861 (2004) |
Heath D. Skinner [États-Unis] ; Jenny Z. Zheng ; Jing Fang ; Faton Agani ; Bing-Hua Jiang | Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling. |
| 001898 (2004) |
Ning Gao [États-Unis] ; Daniel C. Flynn ; Zhuo Zhang ; Xiao-Song Zhong ; Valerie Walker ; Ke Jian Liu ; Xianglin Shi ; Bing-Hua Jiang | G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells. |
| 001923 (2003) |
Kristopher K. Frese [États-Unis] ; Siu Sylvia Lee ; Darby L. Thomas ; Isabel J. Latorre ; Robert S. Weiss ; Britt A. Glaunsinger ; Ronald T. Javier | Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein. |
| 001960 (2002) |
Kevin T. Nguyen [États-Unis] ; Cong S. Zong ; Shailaja Uttamsingh ; Pallavi Sachdev ; Monica Bhanot ; Mai-Thao Le ; Joseph L-K Chan ; Lu-Hai Wang | The role of phosphatidylinositol 3-kinase, rho family GTPases, and STAT3 in Ros-induced cell transformation. |
