List of bibliographic references indexed by Relation structure-activité (MeSH)
Number of relevant bibliographic references: 21.
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0 - 20][
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Ident. | Authors (with country if any) | Title |
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000341 (2019) |
Saleem Ahmad [République populaire de Chine] ; Sen Wang [République populaire de Chine] ; Weizhong Wu [République populaire de Chine] ; Kunlong Yang [République populaire de Chine] ; Yan Feng Zhang [République populaire de Chine] ; Elisabeth Tumukunde [République populaire de Chine] ; Shihua Wang [République populaire de Chine] ; Yu Wang [République populaire de Chine] | Functional Analysis of Peptidyl-prolyl cis-trans Isomerase from Aspergillus flavus. |
000411 (2019) |
Denise Rageot [Suisse] ; Thomas Bohnacker [Suisse] ; Erhan Keles [Suisse] ; Jacob A. Mcphail [Canada] ; Reece M. Hoffmann [Canada] ; Anna Melone [Suisse] ; Chiara Borsari [Suisse] ; Rohitha Sriramaratnam [Suisse] ; Alexander M. Sele [Suisse] ; Florent Beaufils [Suisse] ; Paul Hebeisen [Suisse] ; Doriano Fabbro [Suisse] ; Petra Hillmann [Suisse] ; John E. Burke [Canada] ; Matthias P. Wymann [Suisse] | (S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine (PQR530), a Potent, Orally Bioavailable, and Brain-Penetrable Dual Inhibitor of Class I PI3K and mTOR Kinase. |
000483 (2018) |
Qingwen Huang [République populaire de Chine] ; Lijun Xie [République populaire de Chine] ; Xiaoming Chen [République populaire de Chine] ; Hui Yu [République populaire de Chine] ; Yubing Lv [République populaire de Chine] ; Xuehui Huang [République populaire de Chine] ; Jiayin Ying [République populaire de Chine] ; Congshen Zheng [République populaire de Chine] ; Yuanrong Cheng [République populaire de Chine] ; Jie Huang [République populaire de Chine] | Synthesis and anticancer activity of novel rapamycin C-28 containing triazole moiety compounds. |
000605 (2018) |
Ruth Martín [Norvège] ; Sandra Lopez-Aviles [Norvège] | Express yourself: how PP2A-B55Pab1 helps TORC1 talk to TORC2. |
000999 (2016) |
Lijun Xie [République populaire de Chine] ; Jie Huang [République populaire de Chine] ; Xiaoming Chen [République populaire de Chine] ; Hui Yu [République populaire de Chine] ; Kualiang Li [République populaire de Chine] ; Dan Yang [République populaire de Chine] ; Xiaqin Chen [République populaire de Chine] ; Jiayin Ying [République populaire de Chine] ; Fusheng Pan [République populaire de Chine] ; Youbing Lv [République populaire de Chine] ; Yuanrong Cheng [République populaire de Chine] | Synthesis of Rapamycin Derivatives Containing the Triazole Moiety Used as Potential mTOR-Targeted Anticancer Agents. |
000F75 (2013) |
Yoan R. Monneau [France] ; Heddy Soufari ; Christopher J. Nelson ; Cameron D. Mackereth | Structure and activity of the peptidyl-prolyl isomerase domain from the histone chaperone Fpr4 toward histone H3 proline isomerization. |
001360 (2011) |
Isabel Rodríguez-Escudero [Espagne] ; María D. Oliver ; Amparo Andrés-Pons ; María Molina ; Víctor J. Cid ; Rafael Pulido | A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromes. |
001395 (2010) |
T. Sato [États-Unis] ; A. Nakashima ; L. Guo ; K. Coffman ; F. Tamanoi | Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancer. |
001693 (2007) |
Fumiaki Ikeda [Japon] ; Shigeki Tanaka ; Hidenori Ohki ; Satoru Matsumoto ; Katsuyuki Maki ; Masataka Katashima ; David Barrett ; Yoshiyasu Aoki | Role of micafungin in the antifungal armamentarium. |
001794 (2006) |
Suzanne D. Clutter [États-Unis] ; James E. Fortney ; Laura F. Gibson | Chemotherapy disrupts activity of translational regulatory proteins in bone marrow stromal cells. |
001808 (2005) |
Sonja A. Dames [Suisse] ; José M. Mulet ; Klara Rathgeb-Szabo ; Michael N. Hall ; Stephan Grzesiek | The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability. |
001818 (2005) |
Christine Van Hoof [Belgique] ; Ellen Martens ; Sari Longin ; Jan Jordens ; Ilse Stevens ; Veerle Janssens ; Jozef Goris | Specific interactions of PP2A and PP2A-like phosphatases with the yeast PTPA homologues, Ypa1 and Ypa2. |
001840 (2005) |
E. Foulstone [Royaume-Uni] ; S. Prince ; O. Zaccheo ; J L Burns ; J. Harper ; C. Jacobs ; D. Church ; A B Hassan | Insulin-like growth factor ligands, receptors, and binding proteins in cancer. |
001887 (2004) |
Edmund I. Graziani [États-Unis] ; Mia Y. Summers ; Jeffrey E. Janso ; Ker Yu ; Valerie S. Bernan ; Michael Greenstein ; Guy T. Carter | Isolation, structure determination and biological activity of 15-deoxo-7,32-O-didesmethylrapamycin from the soil actinomycete LL-D45042. |
001901 (2004) |
Jana Narasimhan [États-Unis] ; Kirk A. Staschke ; Ronald C. Wek | Dimerization is required for activation of eIF2 kinase Gcn2 in response to diverse environmental stress conditions. |
001959 (2002) |
Alleyn T. Plowright [États-Unis] ; Scott E. Schaus ; Andrew G. Myers | Transcriptional response pathways in a yeast strain sensitive to saframycin a and a more potent analog: evidence for a common basis of activity. |
001A04 (2001) |
A C Gingras [Canada] ; B. Raught ; N. Sonenberg | Regulation of translation initiation by FRAP/mTOR. |
001A94 (1996) |
A. Bell [Irlande (pays)] ; H C Roberts ; L H Chappell | The antiparasite effects of cyclosporin A: possible drug targets and clinical applications. |
001B12 (1995) |
J I Luengo [États-Unis] ; D S Yamashita ; D. Dunnington ; A K Beck ; L W Rozamus ; H K Yen ; M J Bossard ; M A Levy ; A. Hand ; T. Newman-Tarr | Structure-activity studies of rapamycin analogs: evidence that the C-7 methoxy group is part of the effector domain and positioned at the FKBP12-FRAP interface. |
001B30 (1994) |
M J Bossard [États-Unis] ; D J Bergsma ; M. Brandt ; G P Livi ; W K Eng ; R K Johnson ; M A Levy | Catalytic and ligand binding properties of the FK506 binding protein FKBP12: effects of the single amino acid substitution of Tyr82 to Leu. |
001B34 (1993) |
P L Koser [États-Unis] ; W K Eng ; M J Bossard ; M M Mclaughlin ; R. Cafferkey ; G M Sathe ; L. Faucette ; M A Levy ; R K Johnson ; D J Bergsma ; G P Livi | The tyrosine89 residue of yeast FKBP12 is required for rapamycin binding. |
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