List of bibliographic references indexed by Phosphatidylinositol 3-kinases (composition chimique)
Number of relevant bibliographic references: 19.
| Ident. | Authors (with country if any) | Title |
|---|
| 000469 (2018) |
Maristella De Cicco [Allemagne] ; Lech-G Milroy [Pays-Bas] ; Sonja A. Dames [Allemagne] | Target of rapamycin FATC domain as a general membrane anchor: The FKBP-12 like domain of FKBP38 as a case study. |
| 000509 (2018) |
Andrew Hill [États-Unis] ; Brad Niles [États-Unis] ; Andrew Cuyegkeng [États-Unis] ; Ted Powers [États-Unis] | Redesigning TOR Kinase to Explore the Structural Basis for TORC1 and TORC2 Assembly. |
| 000539 (2018) |
Gabriel Castro-Falc N [États-Unis] ; Grant S. Seiler [États-Unis] ; Özlem Demir [États-Unis] ; Manoj K. Rathinaswamy [Canada] ; David Hamelin [Canada] ; Reece M. Hoffmann [Canada] ; Stefanie L. Makowski [États-Unis] ; Anne-Catrin Letzel [États-Unis] ; Seth J. Field [États-Unis] ; John E. Burke [Canada] ; Rommie E. Amaro [États-Unis] ; Chambers C. Hughes [États-Unis] | Neolymphostin A Is a Covalent Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitor That Employs an Unusual Electrophilic Vinylogous Ester. |
| 000619 (2018) |
Denise Rageot [Suisse] ; Thomas Bohnacker [Suisse] ; Anna Melone [Suisse] ; Jean-Baptiste Langlois [Suisse] ; Chiara Borsari [Suisse] ; Petra Hillmann [Suisse] ; Alexander M. Sele [Suisse] ; Florent Beaufils [Suisse] ; Marketa Zvelebil [Suisse] ; Paul Hebeisen [Suisse] ; Wolfgang Löscher [Allemagne] ; John Burke [Canada] ; Doriano Fabbro [Suisse] ; Matthias P. Wymann [Suisse] | Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1/2 Inhibitor for Cancer and Neurological Disorders. |
| 000629 (2018) |
Iva Lu I [Autriche] ; Manoj K. Rathinaswamy [Canada] ; Linda Truebestein [Autriche] ; David J. Hamelin [Canada] ; John E. Burke [Canada] ; Thomas A. Leonard [Autriche] | Conformational sampling of membranes by Akt controls its activation and inactivation. |
| 000C63 (2015) |
Christl Gaubitz [Suisse] ; Taiana M. Oliveira [France] ; Manoel Prouteau [Suisse] ; Alexander Leitner [Suisse] ; Manikandan Karuppasamy [France] ; Georgia Konstantinidou [Suisse] ; Delphine Rispal [Suisse] ; Sandra Eltschinger [Suisse] ; Graham C. Robinson [Suisse] ; Stéphane Thore [France] ; Ruedi Aebersold [Suisse] ; Christiane Schaffitzel [Royaume-Uni] ; Robbie Loewith [Suisse] | Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2. |
| 000E97 (2014) |
Carrie L. Lucas [États-Unis] ; Hye Sun Kuehn [États-Unis] ; Fang Zhao [États-Unis] ; Julie E. Niemela [États-Unis] ; Elissa K. Deenick [Australie] ; Umaimainthan Palendira [Australie] ; Danielle T. Avery [Australie] ; Leen Moens [Australie] ; Jennifer L. Cannons [États-Unis] ; Matthew Biancalana [États-Unis] ; Jennifer Stoddard [États-Unis] ; Weiming Ouyang [États-Unis] ; David M. Frucht [États-Unis] ; V Koneti Rao [États-Unis] ; T Prescott Atkinson [États-Unis] ; Anahita Agharahimi [États-Unis] ; Ashleigh A. Hussey [États-Unis] ; Les R. Folio [États-Unis] ; Kenneth N. Olivier [États-Unis] ; Thomas A. Fleisher [États-Unis] ; Stefania Pittaluga [États-Unis] ; Steven M. Holland [États-Unis] ; Jeffrey I. Cohen [États-Unis] ; Joao B. Oliveira [Brésil] ; Stuart G. Tangye [Australie] ; Pamela L. Schwartzberg [États-Unis] ; Michael J. Lenardo [États-Unis] ; Gulbu Uzel [États-Unis] | Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency. |
| 000F08 (2014) |
Lisa A M. Sommer [Allemagne] ; J Joel Janke ; W F Drew Bennett ; Jochen Bürck ; Anne S. Ulrich ; D Peter Tieleman ; Sonja A. Dames | Characterization of the immersion properties of the peripheral membrane anchor of the FATC domain of the kinase "target of rapamycin" by NMR, oriented CD spectroscopy, and MD simulations. |
| 000F10 (2014) |
Lisa A M. Sommer [Allemagne] ; Sonja A. Dames [Allemagne] | Characterization of residue-dependent differences in the peripheral membrane association of the FATC domain of the kinase 'target of rapamycin' by NMR and CD spectroscopy. |
| 001244 (2011) |
Nobuyasu Ikai [Japon] ; Norihiko Nakazawa ; Takeshi Hayashi ; Mitsuhiro Yanagida | The reverse, but coordinated, roles of Tor2 (TORC1) and Tor1 (TORC2) kinases for growth, cell cycle and separase-mediated mitosis in Schizosaccharomyces pombe. |
| 001329 (2011) |
Rui Gong [République populaire de Chine] ; Li Li ; Yi Liu ; Ping Wang ; Huirong Yang ; Ling Wang ; Jingdong Cheng ; Kun-Liang Guan ; Yanhui Xu | Crystal structure of the Gtr1p-Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation. |
| 001548 (2009) |
Thomas W. Sturgill [États-Unis] ; Michael N. Hall | Activating mutations in TOR are in similar structures as oncogenic mutations in PI3KCalpha. |
| 001581 (2008) |
Thomas W. Sturgill [États-Unis] ; Adiel Cohen ; Melanie Diefenbacher ; Mark Trautwein ; Dietmar E. Martin ; Michael N. Hall | TOR1 and TOR2 have distinct locations in live cells. |
| 001681 (2007) |
Alessandra Adami [Royaume-Uni] ; Bego A García-Alvarez ; Ernesto Arias-Palomo ; David Barford ; Oscar Llorca | Structure of TOR and its complex with KOG1. |
| 001699 (2007) |
Takeshi Hayashi [Japon] ; Mitsuko Hatanaka ; Koji Nagao ; Yukinobu Nakaseko ; Junko Kanoh ; Aya Kokubu ; Masahiro Ebe ; Mitsuhiro Yanagida | Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits. |
| 001797 (2006) |
Aaron Reinke [États-Unis] ; Jenny C-Y Chen ; Sofia Aronova ; Ted Powers | Caffeine targets TOR complex I and provides evidence for a regulatory link between the FRB and kinase domains of Tor1p. |
| 001808 (2005) |
Sonja A. Dames [Suisse] ; José M. Mulet ; Klara Rathgeb-Szabo ; Michael N. Hall ; Stephan Grzesiek | The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability. |
| 001833 (2005) |
Stephan Wullschleger [Suisse] ; Robbie Loewith ; Wolfgang Oppliger ; Michael N. Hall | Molecular organization of target of rapamycin complex 2. |
| 001872 (2004) |
Aaron Reinke [États-Unis] ; Scott Anderson ; J Michael Mccaffery ; John Yates ; Sofia Aronova ; Stephanie Chu ; Stephen Fairclough ; Cory Iverson ; Karen P. Wedaman ; Ted Powers | TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae. |
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