| Ident. | Authors (with country if any) | Title |
|---|
| 000071 (2020) |
Yuko Fujioka [Japon] ; Jahangir Md Alam [Japon] ; Daisuke Noshiro [Japon] ; Kazunari Mouri [Japon] ; Toshio Ando [Japon] ; Yasushi Okada [Japon] ; Alexander I. May [Japon] ; Roland L. Knorr [Allemagne, Japon] ; Kuninori Suzuki [Japon] ; Yoshinori Ohsumi [Japon] ; Nobuo N. Noda [Japon] | Phase separation organizes the site of autophagosome formation. |
| 000084 (2020) |
Wipawee Saenwongsa [Thaïlande] ; Arnone Nithichanon [Thaïlande] ; Malinee Chittaganpitch [Thaïlande] ; Kampaew Buayai [Thaïlande] ; Chidchamai Kewcharoenwong [Thaïlande] ; Boonyarat Thumrongwilainet [Thaïlande] ; Patcharavadee Butta [Thaïlande] ; Tanapat Palaga [Thaïlande] ; Yoshimasa Takahashi [Japon] ; Manabu Ato [Japon] ; Ganjana Lertmemongkolchai [Thaïlande] | Metformin-induced suppression of IFN-α via mTORC1 signalling following seasonal vaccination is associated with impaired antibody responses in type 2 diabetes. |
| 000103 (2020) |
Gotaro Toda [Japon] ; Kotaro Soeda [Japon] ; Yukiko Okazaki [Japon] ; Naoki Kobayashi [Japon] ; Yukari Masuda [Japon] ; Naoko Arakawa [Japon] ; Hirotsugu Suwanai [Japon] ; Yosuke Masamoto [Japon] ; Yoshihiko Izumida [Japon] ; Nozomu Kamei [Japon] ; Takayoshi Sasako [Japon] ; Ryo Suzuki [Japon] ; Tetsuya Kubota [Japon] ; Naoto Kubota [Japon] ; Mineo Kurokawa [Japon] ; Kazuyuki Tobe [Japon] ; Tetsuo Noda [Japon] ; Kenya Honda [Japon] ; Domenico Accili [États-Unis] ; Toshimasa Yamauchi [Japon] ; Takashi Kadowaki [Japon] ; Kohjiro Ueki [Japon] | Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation. |
| 000115 (2020) |
Hirotaka Toh [Japon] ; Takashi Nozawa [Japon] ; Atsuko Minowa-Nozawa [Japon] ; Miyako Hikichi [Japon] ; Shintaro Nakajima [Japon] ; Chihiro Aikawa [Japon] ; Ichiro Nakagawa [Japon] | Group A Streptococcus modulates RAB1- and PIK3C3 complex-dependent autophagy. |
| 000119 (2020) |
Koji Kasahara [Japon] ; Risa Nakayama [Japon] ; Yuh Shiwa [Japon] ; Yu Kanesaki [Japon] ; Taichiro Ishige [Japon] ; Hirofumi Yoshikawa [Japon] ; Tetsuro Kokubo [Japon] | Fpr1, a primary target of rapamycin, functions as a transcription factor for ribosomal protein genes cooperatively with Hmo1 in Saccharomyces cerevisiae. |
| 000126 (2020) |
Jun Arii [Japon] ; Fumio Maeda [Japon] ; Yuhei Maruzuru [Japon] ; Naoto Koyanagi [Japon] ; Akihisa Kato [Japon] ; Yasuko Mori [Japon] ; Yasushi Kawaguchi [Japon] | ESCRT-III controls nuclear envelope deformation induced by progerin. |
| 000159 (2020) |
Tetsushi Kataura [Japon] ; Etsu Tashiro [Japon] ; Shota Nishikawa [Japon] ; Kensuke Shibahara [Japon] ; Yoshihito Muraoka [Japon] ; Masahiro Miura [Japon] ; Shun Sakai [Japon] ; Naohiro Katoh [Japon] ; Misato Totsuka [Japon] ; Masafumi Onodera [Japon] ; Kazuo Shin-Ya [Japon] ; Kengo Miyamoto [Japon] ; Yukiko Sasazawa [Japon] ; Nobutaka Hattori [Japon] ; Shinji Saiki [Japon] ; Masaya Imoto [Japon] | A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers. |
| 000252 (2019) |
Takayuki Imanishi [Japon] ; Midori Unno [Japon] ; Wakana Kobayashi [Japon] ; Natsumi Yoneda [Japon] ; Satoshi Matsuda [Japon] ; Kazutaka Ikeda [Japon] ; Takayuki Hoshii [Japon] ; Atsushi Hirao [Japon] ; Kensuke Miyake [Japon] ; Glen N. Barber [États-Unis] ; Makoto Arita [Japon] ; Ken J. Ishii [Japon] ; Shizuo Akira [Japon] ; Takashi Saito [Japon] | Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function. |
| 000267 (2019) |
Daisuke Watanabe [Japon] ; Takuma Kajihara [Japon] ; Yukiko Sugimoto [Japon] ; Kenichi Takagi [Japon] ; Megumi Mizuno [Japon] ; Yan Zhou [Japon] ; Jiawen Chen [Japon] ; Kojiro Takeda [Japon] ; Hisashi Tatebe [Japon] ; Kazuhiro Shiozaki [Japon] ; Nobushige Nakazawa [Japon] ; Shingo Izawa [Japon] ; Takeshi Akao [Japon] ; Hitoshi Shimoi [Japon] ; Tatsuya Maeda [Japon] ; Hiroshi Takagi [Japon] | Nutrient Signaling via the TORC1-Greatwall-PP2AB55δ Pathway Is Responsible for the High Initial Rates of Alcoholic Fermentation in Sake Yeast Strains of Saccharomyces cerevisiae. |
| 000347 (2019) |
Kensuke Miyake [Japon] ; Shin-Ichiroh Saitoh [Japon] ; Ryota Sato [Japon] ; Takuma Shibata [Japon] ; Ryutaro Fukui [Japon] ; Yusuke Murakami [Japon] | Endolysosomal compartments as platforms for orchestrating innate immune and metabolic sensors. |
| 000416 (2018) |
Yoko Otsubo [Japon] ; Tomohiko Matsuo [Japon] ; Akiko Nishimura [Japon] ; Masayuki Yamamoto [Japon] ; Akira Yamashita [Japon] | tRNA production links nutrient conditions to the onset of sexual differentiation through the TORC1 pathway. |
| 000473 (2018) |
Natsumi Kawasaki [Japon] ; Kazunobu Isogaya [Japon] ; Shingo Dan [Japon] ; Takao Yamori [Japon] ; Hiroshi Takano [Japon] ; Ryoji Yao [Japon] ; Yasuyuki Morishita [Japon] ; Luna Taguchi [Japon] ; Masato Morikawa [Japon, Suède] ; Carl-Henrik Heldin [Suède] ; Tetsuo Noda [Japon] ; Shogo Ehata [Japon] ; Kohei Miyazono [Japon, Suède] ; Daizo Koinuma [Japon] | TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling. |
| 000504 (2018) |
Mitsuhiro Kanamori [Japon] ; Hiroko Nakatsukasa [Japon] ; Minako Ito [Japon] ; Shunsuke Chikuma [Japon] ; Akihiko Yoshimura [Japon] | Reprogramming of Th1 cells into regulatory T cells through rewiring of the metabolic status. |
| 000591 (2018) |
Ik-Jung Kim [États-Unis] ; Jeongmin Lee [États-Unis] ; Seung J. Oh [États-Unis] ; Mee-Sup Yoon [Corée du Sud] ; Sung-Soo Jang [États-Unis] ; Robin L. Holland [États-Unis] ; Michael L. Reno [États-Unis] ; Mohammed N. Hamad [États-Unis] ; Tatsuya Maeda [Japon] ; Hee Jung Chung [États-Unis] ; Jie Chen [États-Unis] ; Steven R. Blanke [États-Unis] | Helicobacter pylori Infection Modulates Host Cell Metabolism through VacA-Dependent Inhibition of mTORC1. |
| 000633 (2018) |
Ryota Sato [Japon] ; Akihisa Kato [Japon] ; Takahiko Chimura [Japon] ; Shin-Ichiroh Saitoh [Japon] ; Takuma Shibata [Japon] ; Yusuke Murakami [Japon] ; Ryutaro Fukui [Japon] ; Kaiwen Liu [Japon] ; Yun Zhang [Japon] ; Jun Arii [Japon] ; Ge-Hong Sun-Wada [Japon] ; Yoh Wada [Japon] ; Tsuneo Ikenoue [Japon] ; Glen N. Barber [États-Unis] ; Toshiya Manabe [Japon] ; Yasushi Kawaguchi [Japon] ; Kensuke Miyake [Japon] | Combating herpesvirus encephalitis by potentiating a TLR3-mTORC2 axis. |
| 000642 (2018) |
Md Golam Mostofa [Japon] ; Muhammad Arifur Rahman [Japon] ; Naoki Koike [Japon] ; Akter Mst Yeasmin [Japon] ; Nafisa Islam [Japon] ; Talukdar Muhammad Waliullah [Japon] ; Shun Hosoyamada [Japon] ; Mitsugu Shimobayashi [Suisse] ; Takehiko Kobayashi [Japon] ; Michael N. Hall [Suisse] ; Takashi Ushimaru [Oman, Japon] | CLIP and cohibin separate rDNA from nucleolar proteins destined for degradation by nucleophagy. |
| 000673 (2018) |
Wakana Saso [Japon] ; Senko Tsukuda [Japon] ; Hirofumi Ohashi [Japon] ; Kento Fukano [Japon] ; Ryo Morishita [Japon] ; Satoko Matsunaga [Japon] ; Mio Ohki [Japon] ; Akihide Ryo [Japon] ; Sam-Yong Park [Japon] ; Ryosuke Suzuki [Japon] ; Hideki Aizaki [Japon] ; Masamichi Muramatsu [Japon] ; Camille Sureau [France] ; Takaji Wakita [Japon] ; Tetsuro Matano [Japon] ; Koichi Watashi [Japon] | A new strategy to identify hepatitis B virus entry inhibitors by AlphaScreen technology targeting the envelope-receptor interaction. |
| 000693 (2017) |
Tomoko Kawamata ; Tetsuro Horie [Japon] ; Miou Matsunami ; Michiko Sasaki ; Yoshinori Ohsumi [Japon] | Zinc starvation induces autophagy in yeast. |
| 000733 (2017) |
Shin-Ichiroh Saitoh [Japon] ; Fumiko Abe [Japon] ; Atsuo Kanno [Japon] ; Natsuko Tanimura [Japon] ; Yoshiko Mori Saitoh [Japon] ; Ryutaro Fukui [Japon] ; Takuma Shibata [Japon] ; Katsuaki Sato [Japon] ; Takeshi Ichinohe [Japon] ; Mayumi Hayashi [Japon] ; Kazuishi Kubota [Japon] ; Hiroko Kozuka-Hata [Japon] ; Masaaki Oyama [Japon] ; Yorifumi Kikko [Japon] ; Toshiaki Katada [Japon] ; Kenji Kontani [Japon] ; Kensuke Miyake [Japon] | TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells. |
| 000744 (2017) |
Kayo Ikeda [Japon] ; Makoto Kinoshita [Japon] ; Hisako Kayama [Japon] ; Shushi Nagamori [Japon] ; Pornparn Kongpracha [Japon] ; Eiji Umemoto [Japon] ; Ryu Okumura [Japon] ; Takashi Kurakawa [Japon] ; Mari Murakami [Japon] ; Norihisa Mikami [Japon] ; Yasunori Shintani [Japon] ; Satoko Ueno [Japon] ; Ayatoshi Andou [Japon] ; Morihiro Ito [Japon] ; Hideki Tsumura [Japon] ; Koji Yasutomo [Japon] ; Keiichi Ozono [Japon] ; Seiji Takashima [Japon] ; Shimon Sakaguchi [Japon] ; Yoshikatsu Kanai [Japon] ; Kiyoshi Takeda [Japon] | Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells. |
| 000918 (2017) |
Yuki Kunisada [Japon] ; Shingo Eikawa [Japon] ; Nahoko Tomonobu [Japon] ; Shohei Domae [Japon] ; Takenori Uehara [Japon] ; Shohei Hori [Japon] ; Yukihiro Furusawa [Japon] ; Koji Hase [Japon] ; Akira Sasaki [Japon] ; Heiichiro Udono [Japon] | Attenuation of CD4+CD25+ Regulatory T Cells in the Tumor Microenvironment by Metformin, a Type 2 Diabetes Drug. |
| 000928 (2017) |
Mirai Tanigawa [Japon] ; Tatsuya Maeda [Japon] | An In Vitro TORC1 Kinase Assay That Recapitulates the Gtr-Independent Glutamine-Responsive TORC1 Activation Mechanism on Yeast Vacuoles. |
| 000948 (2016) |
Koji Taniguchi [États-Unis, Japon] ; Shinichiro Yamachika [États-Unis] ; Feng He [États-Unis] ; Michael Karin [États-Unis] | p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer. |
| 000949 (2016) |
Atsushi Umemura [Japon] ; Feng He [États-Unis] ; Koji Taniguchi [Japon] ; Hayato Nakagawa [Japon] ; Shinichiro Yamachika [États-Unis] ; Joan Font-Burgada [États-Unis] ; Zhenyu Zhong [États-Unis] ; Shankar Subramaniam [États-Unis] ; Sindhu Raghunandan [États-Unis] ; Angeles Duran [États-Unis] ; Juan F. Linares [États-Unis] ; Miguel Reina-Campos [États-Unis] ; Shiori Umemura [Japon] ; Mark A. Valasek [États-Unis] ; Ekihiro Seki [États-Unis] ; Kanji Yamaguchi [Japon] ; Kazuhiko Koike [Japon] ; Yoshito Itoh [Japon] ; Maria T. Diaz-Meco [États-Unis] ; Jorge Moscat [États-Unis] ; Michael Karin [États-Unis] | p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells. |
| 000952 (2016) |
David R. Driscoll [États-Unis] ; Saadia A. Karim [Royaume-Uni] ; Makoto Sano [Japon] ; David M. Gay [Royaume-Uni] ; Wright Jacob [Royaume-Uni] ; Jun Yu [États-Unis] ; Yusuke Mizukami [États-Unis] ; Aarthi Gopinathan [Royaume-Uni] ; Duncan I. Jodrell [Royaume-Uni] ; T R Jeffry Evans [Royaume-Uni] ; Nabeel Bardeesy [États-Unis] ; Michael N. Hall [Suisse] ; Brian J. Quattrochi [États-Unis] ; David S. Klimstra [États-Unis] ; Simon T. Barry [Royaume-Uni] ; Owen J. Sansom [Royaume-Uni] ; Brian C. Lewis [États-Unis] ; Jennifer P. Morton [Royaume-Uni] | mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer. |
| 000C25 (2015) |
Tatsuhiro Sato [Japon] ; Hitomi Akasu ; Wataru Shimono ; Chisa Matsu ; Yuki Fujiwara ; Yoshio Shibagaki ; Jeffrey J. Heard ; Fuyuhiko Tamanoi ; Seisuke Hattori | Rheb protein binds CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamoylase, and dihydroorotase) protein in a GTP- and effector domain-dependent manner and influences its cellular localization and carbamoyl-phosphate synthetase (CPSase) activity. |
| 000C58 (2015) |
Tatsuo Adachi [Japon] ; Yasuhiko Matsumoto ; Yoshinori Inagaki ; Kazuhisa Sekimizu | Niemann-Pick disease type C2 protein induces autophagy and inhibits growth in FM3A breast cancer cells. |
| 000E11 (2014) |
Yoko Otsubo [Japon] ; Akira Yamashita [Japon] ; Hayao Ohno [Japon] ; Masayuki Yamamoto [Japon] | S. pombe TORC1 activates the ubiquitin-proteasomal degradation of the meiotic regulator Mei2 in cooperation with Pat1 kinase. |
| 000F23 (2014) |
Han-Ming Shen [Singapour] ; Noboru Mizushima [Japon] | At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy. |
| 000F90 (2013) |
Shigenori Nagai [Japon] ; Yutaka Kurebayashi ; Shigeo Koyasu | Role of PI3K/Akt and mTOR complexes in Th17 cell differentiation. |
| 001049 (2013) |
Shin Yanagisawa [Japon] ; Takashi Kikuma ; Katsuhiko Kitamoto | Functional analysis of Aoatg1 and detection of the Cvt pathway in Aspergillus oryzae. |
| 001052 (2013) |
Kuninori Suzuki [Japon] ; Manami Akioka ; Chika Kondo-Kakuta ; Hayashi Yamamoto ; Yoshinori Ohsumi | Fine mapping of autophagy-related proteins during autophagosome formation in Saccharomyces cerevisiae. |
| 001100 (2012) |
Terunao Takahara [Japon] ; Tatsuya Maeda | Transient sequestration of TORC1 into stress granules during heat stress. |
| 001114 (2012) |
Terunao Takahara [Japon] ; Tatsuya Maeda | TORC1 of fission yeast is rapamycin-sensitive. |
| 001117 (2012) |
Teruhiko Imamura [Japon] ; Taro Shiga ; Koichiro Kinugawa ; Naoko Kato ; Miyoko Endo ; Toshiro Inaba ; Hisataka Maki ; Masaru Hatano ; Atsushi Yao ; Yasunobu Hirata ; Ryozo Nagai | Successful conversion to everolimus after cytomegalovirus infection in a heart transplant recipient. |
| 001145 (2012) |
Yutaka Kurebayashi [Japon] ; Shigenori Nagai ; Ai Ikejiri ; Masashi Ohtani ; Kenji Ichiyama ; Yukiko Baba ; Taketo Yamada ; Shohei Egami ; Takayuki Hoshii ; Atsushi Hirao ; Satoshi Matsuda ; Shigeo Koyasu | PI3K-Akt-mTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi1 expression and nuclear translocation of RORγ. |
| 001198 (2012) |
Ai Ikejiri [Japon] ; Shigenori Nagai ; Nobuhito Goda ; Yutaka Kurebayashi ; Mayuko Osada-Oka ; Keiyo Takubo ; Toshio Suda ; Shigeo Koyasu | Dynamic regulation of Th17 differentiation by oxygen concentrations. |
| 001526 (2009) |
Yoichiro Ohne [Japon] ; Terunao Takahara ; Tatsuya Maeda | Evaluation of mTOR function by a gain-of-function approach. |
| 001555 (2008) |
Yoko Otsubo [Japon] ; Masayuki Yamamato | TOR signaling in fission yeast. |
| 001613 (2008) |
Masashi Ohtani [Japon] ; Shigenori Nagai ; Shuhei Kondo ; Shinta Mizuno ; Kozue Nakamura ; Masanobu Tanabe ; Tsutomu Takeuchi ; Satoshi Matsuda ; Shigeo Koyasu | Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells. |
| 001693 (2007) |
Fumiaki Ikeda [Japon] ; Shigeki Tanaka ; Hidenori Ohki ; Satoru Matsumoto ; Katsuyuki Maki ; Masataka Katashima ; David Barrett ; Yoshiyasu Aoki | Role of micafungin in the antifungal armamentarium. |
| 001715 (2007) |
Tomohiko Matsuo [Japon] ; Yoko Otsubo ; Jun Urano ; Fuyuhiko Tamanoi ; Masayuki Yamamoto | Loss of the TOR kinase Tor2 mimics nitrogen starvation and activates the sexual development pathway in fission yeast. |
| 001764 (2006) |
Terunao Takahara [Japon] ; Kenta Hara ; Kazuyoshi Yonezawa ; Hiroyuki Sorimachi ; Tatsuya Maeda | Nutrient-dependent multimerization of the mammalian target of rapamycin through the N-terminal HEAT repeat region. |
| 001785 (2006) |
Takashi Kikuma [Japon] ; Mamoru Ohneda ; Manabu Arioka ; Katsuhiko Kitamoto | Functional analysis of the ATG8 homologue Aoatg8 and role of autophagy in differentiation and germination in Aspergillus oryzae. |
| 001838 (2005) |
Tomoyuki Araki [Japon] ; Yukifumi Uesono ; Tomoko Oguchi ; Akio Toh-E | LAS24/KOG1, a component of the TOR complex 1 (TORC1), is needed for resistance to local anesthetic tetracaine and normal distribution of actin cytoskeleton in yeast. |
| 001936 (2003) |
Yuri Nagai [Japon] ; Satoru Nogami ; Fumi Kumagai-Sano ; Yoshikazu Ohya | Karyopherin-mediated nuclear import of the homing endonuclease VMA1-derived endonuclease is required for self-propagation of the coding region. |
| 001A15 (2001) |
M. Takahashi [Japon] ; Y. Nakagawa ; J A Berzofsky ; H. Takahashi | Counter-regulation of cytolytic activity and cytokine production in HIV-1-specific murine CD8+ cytotoxic T lymphocytes by free antigenic peptide. |
| 001B05 (1996) |
H. Kitagawa [Japon] ; Y. Hotta ; K. Fujiki ; A. Kanai | Cloning and high expression of rabbit FKBP25 in cornea. |
