OrangerV1, Ncbi, Merge, bibRecord, 000391

Bioavailability and antioxidant effects of orange juice components in humans

Identifieur interne : 000391 ( Ncbi/Merge ); précédent : 000390; suivant : 000392

Bioavailability and antioxidant effects of orange juice components in humans

Auteurs : Adrian A. Franke ; Robert V. Cooney ; Susanne M. Henning [États-Unis] ; Laurie J. Custer

Source :

Journal of agricultural and food chemistry [ 0021-8561 ] ; 2005.

RBID : PMC:2533031

English descriptors

KwdEn :
- Antioxidants (analysis), Antioxidants (pharmacokinetics), Ascorbic Acid (analysis), Ascorbic Acid (blood), Ascorbic Acid (pharmacokinetics), Beverages (analysis), Biological Availability, Carotenoids (administration & dosage), Carotenoids (blood), Carotenoids (pharmacokinetics), Cholesterol, HDL (blood), Cholesterol, LDL (blood), Citrus sinensis (chemistry), Female, Flavanones (administration & dosage), Flavanones (blood), Flavanones (pharmacokinetics), Folic Acid (administration & dosage), Folic Acid (blood), Folic Acid (pharmacokinetics), Fruit (chemistry), Humans, Male, Triglycerides (blood).
MESH :
- chemical , administration & dosage : Carotenoids, Flavanones, Folic Acid.
- chemical , analysis : Antioxidants, Ascorbic Acid.
- chemical , blood : Ascorbic Acid, Carotenoids, Cholesterol, HDL, Cholesterol, LDL, Flavanones, Folic Acid, Triglycerides.
- chemical , pharmacokinetics : Antioxidants, Ascorbic Acid, Carotenoids, Flavanones, Folic Acid.
- analysis : Beverages.
- chemistry : Citrus sinensis, Fruit.
- Biological Availability, Female, Humans, Male.

Abstract

Seven healthy females and six males consumed daily 256 mg vitamin C, 229 mg hesperidin (main flavonoid occurring as glycoside), 6 mg carotenoids (mainly luteins and cryptoxanthins), and 0.16 mg folate by incorporation of daily 236 mL of not-from-concentrate orange juice (OJ) into their habitual diet. At the end of three weeks mean vitamin C, folate, carotenoid, and flavanone plasma concentrations increased significantly relative to baseline by 59% (p<0.001), 46% (p=0.018), and 22% (p<0.001), and 8 fold (p=0.045), respectively. Flavanones were excreted in urine 9 fold more at the end of the intervention (p=0.01) but returned to baseline two days after study completion. After the 3-week intervention plasma concentrations of vitamins A and E did not change. 8-Hydroxy deoxyguanosine (8OHdG) in white blood cells declined by 16% (p=0.38; n=11), and in individuals with high baseline concentrations by 29% (p=0.36; n=7), respectively. LDL-/HDL-cholesterol ratio decreased but cholesterol (HDL, LDL, total) and thiobarbituric acid reactive substance plasma concentrations did not change significantly. We conclude from this pilot study that OJ is an excellent food source to enhance circulating concentrations of valuable hydrophilic as well as lipophilic phytochemicals.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533031

DOI: 10.1021/jf050054y
PubMed: 15969493
PubMed Central: 2533031

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PMC:2533031

Le document en format XML

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<author><name sortKey="Cooney, Robert V" sort="Cooney, Robert V" uniqKey="Cooney R" first="Robert V." last="Cooney">Robert V. Cooney</name>
</author>
<author><name sortKey="Henning, Susanne M" sort="Henning, Susanne M" uniqKey="Henning S" first="Susanne M." last="Henning">Susanne M. Henning</name>
<affiliation wicri:level="2"><nlm:aff id="A1">Center for Human Nutrition, University of California at Los Angeles, CA 90095</nlm:aff>
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<author><name sortKey="Custer, Laurie J" sort="Custer, Laurie J" uniqKey="Custer L" first="Laurie J." last="Custer">Laurie J. Custer</name>
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<term>Ascorbic Acid (pharmacokinetics)</term>
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<term>Fruit (chemistry)</term>
<term>Humans</term>
<term>Male</term>
<term>Triglycerides (blood)</term>
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<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Carotenoids</term>
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<term>Ascorbic Acid</term>
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<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Ascorbic Acid</term>
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<front><div type="abstract" xml:lang="en"><p id="P1">Seven healthy females and six males consumed daily 256 mg vitamin C, 229 mg hesperidin (main flavonoid occurring as glycoside), 6 mg carotenoids (mainly luteins and cryptoxanthins), and 0.16 mg folate by incorporation of daily 236 mL of not-from-concentrate orange juice (OJ) into their habitual diet. At the end of three weeks mean vitamin C, folate, carotenoid, and flavanone plasma concentrations increased significantly relative to baseline by 59% (p<0.001), 46% (p=0.018), and 22% (p<0.001), and 8 fold (p=0.045), respectively. Flavanones were excreted in urine 9 fold more at the end of the intervention (p=0.01) but returned to baseline two days after study completion. After the 3-week intervention plasma concentrations of vitamins A and E did not change. 8-Hydroxy deoxyguanosine (8OHdG) in white blood cells declined by 16% (p=0.38; n=11), and in individuals with high baseline concentrations by 29% (p=0.36; n=7), respectively. LDL-/HDL-cholesterol ratio decreased but cholesterol (HDL, LDL, total) and thiobarbituric acid reactive substance plasma concentrations did not change significantly. We conclude from this pilot study that OJ is an excellent food source to enhance circulating concentrations of valuable hydrophilic as well as lipophilic phytochemicals.</p>
</div>
</front>
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<front><div type="abstract" xml:lang="en"><p id="P1">Seven healthy females and six males consumed daily 256 mg vitamin C, 229 mg hesperidin (main flavonoid occurring as glycoside), 6 mg carotenoids (mainly luteins and cryptoxanthins), and 0.16 mg folate by incorporation of daily 236 mL of not-from-concentrate orange juice (OJ) into their habitual diet. At the end of three weeks mean vitamin C, folate, carotenoid, and flavanone plasma concentrations increased significantly relative to baseline by 59% (p<0.001), 46% (p=0.018), and 22% (p<0.001), and 8 fold (p=0.045), respectively. Flavanones were excreted in urine 9 fold more at the end of the intervention (p=0.01) but returned to baseline two days after study completion. After the 3-week intervention plasma concentrations of vitamins A and E did not change. 8-Hydroxy deoxyguanosine (8OHdG) in white blood cells declined by 16% (p=0.38; n=11), and in individuals with high baseline concentrations by 29% (p=0.36; n=7), respectively. LDL-/HDL-cholesterol ratio decreased but cholesterol (HDL, LDL, total) and thiobarbituric acid reactive substance plasma concentrations did not change significantly. We conclude from this pilot study that OJ is an excellent food source to enhance circulating concentrations of valuable hydrophilic as well as lipophilic phytochemicals.</p>
</div>
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<pubmed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Bioavailability and antioxidant effects of orange juice components in humans.</title>
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<term>Ascorbic Acid (pharmacokinetics)</term>
<term>Beverages (analysis)</term>
<term>Biological Availability</term>
<term>Carotenoids (administration & dosage)</term>
<term>Carotenoids (blood)</term>
<term>Carotenoids (pharmacokinetics)</term>
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<term>Citrus sinensis (chemistry)</term>
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<term>Folic Acid</term>
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<front><div type="abstract" xml:lang="en">Seven healthy females and six males consumed daily 256 mg of vitamin C, 271 mg of flavanones (mainly as glycosides), 6 mg of carotenoids (mainly xanthophylls and cryptoxanthins), and 0.16 mg of folate by incorporation of daily three times 236 mL of not from concentrate orange juice (OJ) into their habitual diet. At the end of 3 weeks, mean vitamin C, folate, carotenoid, and flavanone plasma concentrations increased significantly relative to baseline by 59% (p < 0.001), 46% (p = 0.018), and 22% (p < 0.001), and 8-fold (p = 0.045), respectively. Flavanones were excreted in urine 9-fold more at the end of the intervention (p = 0.01) but returned to baseline 2 days after study completion. After the 3 week intervention, plasma concentrations of vitamins A and E did not change. 8-Hydroxydeoxyguanosine in white blood cells declined by 16% (p = 0.38; n = 11), and in individuals with high baseline concentrations by 29% (p = 0.36; n = 7), respectively. Low-density lipoprotein (LDL)-/high-density lipoprotein (HDL)-cholesterol ratios decreased but cholesterol (HDL, LDL, total) and thiobarbituric acid reactive substance plasma concentrations did not change significantly. We conclude from this pilot study that OJ is an excellent food source to enhance circulating concentrations of valuable hydrophilic as well as lipophilic phytochemicals.</div>
</front>
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Bioavailability and antioxidant effects of orange juice components in humans

Bioavailability and antioxidant effects of orange juice components in humans

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki