In vitro hypoglycemic effects of Butea monosperma Lam. leaves and bark
Identifieur interne : 001581 ( Ncbi/Curation ); précédent : 001580; suivant : 001582In vitro hypoglycemic effects of Butea monosperma Lam. leaves and bark
Auteurs : M. Harish [Inde] ; Faiyaz Ahmed [Inde] ; Asna Urooj [Inde]Source :
- Journal of Food Science and Technology [ 0022-1155 ] ; 2011.
Abstract
The present study evaluated the antidiabetic potential of
Url:
DOI: 10.1007/s13197-011-0496-8
PubMed: 24493888
PubMed Central: 3907641
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">In vitro hypoglycemic effects of <italic>Butea monosperma</italic> Lam. leaves and bark</title><author><name sortKey="Harish, M" sort="Harish, M" uniqKey="Harish M" first="M." last="Harish">M. Harish</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Department of Studies in Food Science and Nutrition, Manasagangotri, University of Mysore, Mysore, 570006 India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Studies in Food Science and Nutrition, Manasagangotri, University of Mysore, Mysore</wicri:regionArea><wicri:noRegion>Mysore</wicri:noRegion></affiliation></author><author><name sortKey="Ahmed, Faiyaz" sort="Ahmed, Faiyaz" uniqKey="Ahmed F" first="Faiyaz" last="Ahmed">Faiyaz Ahmed</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Department of Studies in Food Science and Nutrition, Manasagangotri, University of Mysore, Mysore, 570006 India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Studies in Food Science and Nutrition, Manasagangotri, University of Mysore, Mysore</wicri:regionArea><wicri:noRegion>Mysore</wicri:noRegion></affiliation></author><author><name sortKey="Urooj, Asna" sort="Urooj, Asna" uniqKey="Urooj A" first="Asna" last="Urooj">Asna Urooj</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Department of Studies in Food Science and Nutrition, Manasagangotri, University of Mysore, Mysore, 570006 India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Studies in Food Science and Nutrition, Manasagangotri, University of Mysore, Mysore</wicri:regionArea><wicri:noRegion>Mysore</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24493888</idno><idno type="pmc">3907641</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907641</idno><idno type="RBID">PMC:3907641</idno><idno type="doi">10.1007/s13197-011-0496-8</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">000500</idno><idno type="wicri:Area/Pmc/Curation">000499</idno><idno type="wicri:Area/Pmc/Checkpoint">000E41</idno><idno type="wicri:Area/Ncbi/Merge">001581</idno><idno type="wicri:Area/Ncbi/Curation">001581</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">In vitro hypoglycemic effects of <italic>Butea monosperma</italic> Lam. leaves and bark</title><author><name sortKey="Harish, M" sort="Harish, M" uniqKey="Harish M" first="M." last="Harish">M. Harish</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Department of Studies in Food Science and Nutrition, Manasagangotri, University of Mysore, Mysore, 570006 India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Studies in Food Science and Nutrition, Manasagangotri, University of Mysore, Mysore</wicri:regionArea><wicri:noRegion>Mysore</wicri:noRegion></affiliation></author><author><name sortKey="Ahmed, Faiyaz" sort="Ahmed, Faiyaz" uniqKey="Ahmed F" first="Faiyaz" last="Ahmed">Faiyaz Ahmed</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Department of Studies in Food Science and Nutrition, Manasagangotri, University of Mysore, Mysore, 570006 India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Studies in Food Science and Nutrition, Manasagangotri, University of Mysore, Mysore</wicri:regionArea><wicri:noRegion>Mysore</wicri:noRegion></affiliation></author><author><name sortKey="Urooj, Asna" sort="Urooj, Asna" uniqKey="Urooj A" first="Asna" last="Urooj">Asna Urooj</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Department of Studies in Food Science and Nutrition, Manasagangotri, University of Mysore, Mysore, 570006 India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Studies in Food Science and Nutrition, Manasagangotri, University of Mysore, Mysore</wicri:regionArea><wicri:noRegion>Mysore</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of Food Science and Technology</title><idno type="ISSN">0022-1155</idno><idno type="eISSN">0975-8402</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The present study evaluated the antidiabetic potential of <italic>Butea monosperma</italic> Lam. Kuntze (Fabaceae) leaves and the stem bark using various in vitro techniques. The samples were studied for their effects on glucose adsorption, diffusion, amylolysis kinetics, enteric enzymes and glucose transport across yeast cells. Both the samples adsorbed glucose and the adsorption of glucose increased with increase in glucose concentration. The samples also inhibited movement of glucose across the dialysis membrane to varying degree in both glucose diffusion and amylolysis kinetic experiment models. <italic>B. monosperma</italic> leaves inhibited α-amylase, α-glucosidase and sucrase enzymes in succession to varying degrees, whereas the bark inhibited only α-amylase to a significant extent and slightly activated α-glucosidase and sucrase enzymes. The extracts of both leaves and bark promoted glucose uptake by yeast cells compared to control. Enhancement of glucose uptake was dependent on both the sample and glucose concentration. It was directly proportional to the sample concentration and inversely proportional to the molar concentration of the glucose. From the results of the study, it is inferred that, <italic>B. monosperma</italic> leaves and bark possesses antidiabetic activity. However, these effects need to be confirmed using in vivo models and clinical trials for its effective utilization as therapeutic agents.</p></div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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