Coordination of Cell Cycle Progression and Mitotic Spindle Assembly Involves Histone H3 Lysine 4 Methylation by Set1/COMPASS.
Identifieur interne : 001235 ( PubMed/Corpus ); précédent : 001234; suivant : 001236Coordination of Cell Cycle Progression and Mitotic Spindle Assembly Involves Histone H3 Lysine 4 Methylation by Set1/COMPASS.
Auteurs : Traude H. Beilharz ; Paul F. Harrison ; Douglas Maya Miles ; Michael Ming See ; Uyen Minh Merry Le ; Ming Kalanon ; Melissa Jane Curtis ; Qambar Hasan ; Julie Saksouk ; Thanasis Margaritis ; Frank Holstege ; Vincent Geli ; Bernhard DichtlSource :
- Genetics [ 1943-2631 ] ; 2017.
English descriptors
- KwdEn :
- Chromatin (metabolism), DNA-Binding Proteins (metabolism), Histone-Lysine N-Methyltransferase (genetics), Histone-Lysine N-Methyltransferase (metabolism), Histones (genetics), Histones (metabolism), Lysine (metabolism), M Phase Cell Cycle Checkpoints (physiology), Methylation, Mitosis (physiology), Protein Processing, Post-Translational, Saccharomyces cerevisiae (cytology), Saccharomyces cerevisiae (enzymology), Saccharomyces cerevisiae (genetics), Saccharomyces cerevisiae (metabolism), Saccharomyces cerevisiae Proteins (genetics), Saccharomyces cerevisiae Proteins (metabolism), Spindle Apparatus (metabolism), Transcription Factors (metabolism), Ubiquitination.
- MESH :
- chemical , genetics : Histone-Lysine N-Methyltransferase, Histones, Saccharomyces cerevisiae Proteins.
- chemical , metabolism : Chromatin, DNA-Binding Proteins, Histone-Lysine N-Methyltransferase, Histones, Lysine, Saccharomyces cerevisiae Proteins, Transcription Factors.
- cytology : Saccharomyces cerevisiae.
- enzymology : Saccharomyces cerevisiae.
- genetics : Saccharomyces cerevisiae.
- metabolism : Saccharomyces cerevisiae, Spindle Apparatus.
- physiology : M Phase Cell Cycle Checkpoints, Mitosis.
- Methylation, Protein Processing, Post-Translational, Ubiquitination.
Abstract
Methylation of histone H3 lysine 4 (H3K4) by Set1 complex/COMPASS is a hallmark of eukaryotic chromatin, but it remains poorly understood how this post-translational modification contributes to the regulation of biological processes like the cell cycle. Here, we report a H3K4 methylation-dependent pathway in Saccharomyces cerevisiae that governs toxicity toward benomyl, a microtubule destabilizing drug. Benomyl-sensitive growth of wild-type cells required mono- and dimethylation of H3K4 and Pho23, a PHD-containing subunit of the Rpd3L complex. Δset1 and Δpho23 deletions suppressed defects associated with ipl1-2 aurora kinase mutant, an integral component of the spindle assembly checkpoint during mitosis. Benomyl resistance of Δset1 strains was accompanied by deregulation of all four tubulin genes and the phenotype was suppressed by tub2-423 and Δtub3 mutations, establishing a genetic link between H3K4 methylation and microtubule function. Most interestingly, sine wave fitting and clustering of transcript abundance time series in synchronized cells revealed a requirement for Set1 for proper cell-cycle-dependent gene expression and Δset1 cells displayed delayed entry into S phase. Disruption of G1/S regulation in Δmbp1 and Δswi4 transcription factor mutants duplicated both benomyl resistance and suppression of ipl1-2 as was observed with Δset1 Taken together our results support a role for H3K4 methylation in the coordination of cell-cycle progression and proper assembly of the mitotic spindle during mitosis.
DOI: 10.1534/genetics.116.194852
PubMed: 28049706
Links to Exploration step
pubmed:28049706Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Coordination of Cell Cycle Progression and Mitotic Spindle Assembly Involves Histone H3 Lysine 4 Methylation by Set1/COMPASS.</title><author><name sortKey="Beilharz, Traude H" sort="Beilharz, Traude H" uniqKey="Beilharz T" first="Traude H" last="Beilharz">Traude H. Beilharz</name><affiliation><nlm:affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Harrison, Paul F" sort="Harrison, Paul F" uniqKey="Harrison P" first="Paul F" last="Harrison">Paul F. Harrison</name><affiliation><nlm:affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Miles, Douglas Maya" sort="Miles, Douglas Maya" uniqKey="Miles D" first="Douglas Maya" last="Miles">Douglas Maya Miles</name><affiliation><nlm:affiliation>Marseille Cancer Research Center, U1068 Inserm, UMR7258 CNRS, Aix Marseille University, Institut Paoli-Calmettes, F-13009 Marseille, France. Equipe Labellisée Ligue.</nlm:affiliation></affiliation></author><author><name sortKey="See, Michael Ming" sort="See, Michael Ming" uniqKey="See M" first="Michael Ming" last="See">Michael Ming See</name><affiliation><nlm:affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Le, Uyen Minh Merry" sort="Le, Uyen Minh Merry" uniqKey="Le U" first="Uyen Minh Merry" last="Le">Uyen Minh Merry Le</name><affiliation><nlm:affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Kalanon, Ming" sort="Kalanon, Ming" uniqKey="Kalanon M" first="Ming" last="Kalanon">Ming Kalanon</name><affiliation><nlm:affiliation>Centre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, Victoria 3125, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Curtis, Melissa Jane" sort="Curtis, Melissa Jane" uniqKey="Curtis M" first="Melissa Jane" last="Curtis">Melissa Jane Curtis</name><affiliation><nlm:affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Hasan, Qambar" sort="Hasan, Qambar" uniqKey="Hasan Q" first="Qambar" last="Hasan">Qambar Hasan</name><affiliation><nlm:affiliation>Centre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, Victoria 3125, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Saksouk, Julie" sort="Saksouk, Julie" uniqKey="Saksouk J" first="Julie" last="Saksouk">Julie Saksouk</name><affiliation><nlm:affiliation>Institute of Human Genetics, UPR 1142, CNRS, 34396 Montpellier, France.</nlm:affiliation></affiliation></author><author><name sortKey="Margaritis, Thanasis" sort="Margaritis, Thanasis" uniqKey="Margaritis T" first="Thanasis" last="Margaritis">Thanasis Margaritis</name><affiliation><nlm:affiliation>Molecular Cancer Research, University Medical Center Utrecht-Princess Máxima Center for Pediatric Oncology, 3584 Utrecht, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Holstege, Frank" sort="Holstege, Frank" uniqKey="Holstege F" first="Frank" last="Holstege">Frank Holstege</name><affiliation><nlm:affiliation>Molecular Cancer Research, University Medical Center Utrecht-Princess Máxima Center for Pediatric Oncology, 3584 Utrecht, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Geli, Vincent" sort="Geli, Vincent" uniqKey="Geli V" first="Vincent" last="Geli">Vincent Geli</name><affiliation><nlm:affiliation>Marseille Cancer Research Center, U1068 Inserm, UMR7258 CNRS, Aix Marseille University, Institut Paoli-Calmettes, F-13009 Marseille, France. Equipe Labellisée Ligue Bernhard.Dichtl@deakin.edu.au vincent.geli@inserm.fr.</nlm:affiliation></affiliation></author><author><name sortKey="Dichtl, Bernhard" sort="Dichtl, Bernhard" uniqKey="Dichtl B" first="Bernhard" last="Dichtl">Bernhard Dichtl</name><affiliation><nlm:affiliation>Centre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, Victoria 3125, Australia Bernhard.Dichtl@deakin.edu.au vincent.geli@inserm.fr.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28049706</idno><idno type="pmid">28049706</idno><idno type="doi">10.1534/genetics.116.194852</idno><idno type="wicri:Area/PubMed/Corpus">001235</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001235</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Coordination of Cell Cycle Progression and Mitotic Spindle Assembly Involves Histone H3 Lysine 4 Methylation by Set1/COMPASS.</title><author><name sortKey="Beilharz, Traude H" sort="Beilharz, Traude H" uniqKey="Beilharz T" first="Traude H" last="Beilharz">Traude H. Beilharz</name><affiliation><nlm:affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Harrison, Paul F" sort="Harrison, Paul F" uniqKey="Harrison P" first="Paul F" last="Harrison">Paul F. Harrison</name><affiliation><nlm:affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Miles, Douglas Maya" sort="Miles, Douglas Maya" uniqKey="Miles D" first="Douglas Maya" last="Miles">Douglas Maya Miles</name><affiliation><nlm:affiliation>Marseille Cancer Research Center, U1068 Inserm, UMR7258 CNRS, Aix Marseille University, Institut Paoli-Calmettes, F-13009 Marseille, France. Equipe Labellisée Ligue.</nlm:affiliation></affiliation></author><author><name sortKey="See, Michael Ming" sort="See, Michael Ming" uniqKey="See M" first="Michael Ming" last="See">Michael Ming See</name><affiliation><nlm:affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Le, Uyen Minh Merry" sort="Le, Uyen Minh Merry" uniqKey="Le U" first="Uyen Minh Merry" last="Le">Uyen Minh Merry Le</name><affiliation><nlm:affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Kalanon, Ming" sort="Kalanon, Ming" uniqKey="Kalanon M" first="Ming" last="Kalanon">Ming Kalanon</name><affiliation><nlm:affiliation>Centre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, Victoria 3125, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Curtis, Melissa Jane" sort="Curtis, Melissa Jane" uniqKey="Curtis M" first="Melissa Jane" last="Curtis">Melissa Jane Curtis</name><affiliation><nlm:affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Hasan, Qambar" sort="Hasan, Qambar" uniqKey="Hasan Q" first="Qambar" last="Hasan">Qambar Hasan</name><affiliation><nlm:affiliation>Centre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, Victoria 3125, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Saksouk, Julie" sort="Saksouk, Julie" uniqKey="Saksouk J" first="Julie" last="Saksouk">Julie Saksouk</name><affiliation><nlm:affiliation>Institute of Human Genetics, UPR 1142, CNRS, 34396 Montpellier, France.</nlm:affiliation></affiliation></author><author><name sortKey="Margaritis, Thanasis" sort="Margaritis, Thanasis" uniqKey="Margaritis T" first="Thanasis" last="Margaritis">Thanasis Margaritis</name><affiliation><nlm:affiliation>Molecular Cancer Research, University Medical Center Utrecht-Princess Máxima Center for Pediatric Oncology, 3584 Utrecht, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Holstege, Frank" sort="Holstege, Frank" uniqKey="Holstege F" first="Frank" last="Holstege">Frank Holstege</name><affiliation><nlm:affiliation>Molecular Cancer Research, University Medical Center Utrecht-Princess Máxima Center for Pediatric Oncology, 3584 Utrecht, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Geli, Vincent" sort="Geli, Vincent" uniqKey="Geli V" first="Vincent" last="Geli">Vincent Geli</name><affiliation><nlm:affiliation>Marseille Cancer Research Center, U1068 Inserm, UMR7258 CNRS, Aix Marseille University, Institut Paoli-Calmettes, F-13009 Marseille, France. Equipe Labellisée Ligue Bernhard.Dichtl@deakin.edu.au vincent.geli@inserm.fr.</nlm:affiliation></affiliation></author><author><name sortKey="Dichtl, Bernhard" sort="Dichtl, Bernhard" uniqKey="Dichtl B" first="Bernhard" last="Dichtl">Bernhard Dichtl</name><affiliation><nlm:affiliation>Centre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, Victoria 3125, Australia Bernhard.Dichtl@deakin.edu.au vincent.geli@inserm.fr.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Genetics</title><idno type="eISSN">1943-2631</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Chromatin (metabolism)</term><term>DNA-Binding Proteins (metabolism)</term><term>Histone-Lysine N-Methyltransferase (genetics)</term><term>Histone-Lysine N-Methyltransferase (metabolism)</term><term>Histones (genetics)</term><term>Histones (metabolism)</term><term>Lysine (metabolism)</term><term>M Phase Cell Cycle Checkpoints (physiology)</term><term>Methylation</term><term>Mitosis (physiology)</term><term>Protein Processing, Post-Translational</term><term>Saccharomyces cerevisiae (cytology)</term><term>Saccharomyces cerevisiae (enzymology)</term><term>Saccharomyces cerevisiae (genetics)</term><term>Saccharomyces cerevisiae (metabolism)</term><term>Saccharomyces cerevisiae Proteins (genetics)</term><term>Saccharomyces cerevisiae Proteins (metabolism)</term><term>Spindle Apparatus (metabolism)</term><term>Transcription Factors (metabolism)</term><term>Ubiquitination</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Histone-Lysine N-Methyltransferase</term><term>Histones</term><term>Saccharomyces cerevisiae Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Chromatin</term><term>DNA-Binding Proteins</term><term>Histone-Lysine N-Methyltransferase</term><term>Histones</term><term>Lysine</term><term>Saccharomyces cerevisiae Proteins</term><term>Transcription Factors</term></keywords><keywords scheme="MESH" qualifier="cytology" xml:lang="en"><term>Saccharomyces cerevisiae</term></keywords><keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Saccharomyces cerevisiae</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Saccharomyces cerevisiae</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Saccharomyces cerevisiae</term><term>Spindle Apparatus</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>M Phase Cell Cycle Checkpoints</term><term>Mitosis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Methylation</term><term>Protein Processing, Post-Translational</term><term>Ubiquitination</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Methylation of histone H3 lysine 4 (H3K4) by Set1 complex/COMPASS is a hallmark of eukaryotic chromatin, but it remains poorly understood how this post-translational modification contributes to the regulation of biological processes like the cell cycle. Here, we report a H3K4 methylation-dependent pathway in Saccharomyces cerevisiae that governs toxicity toward benomyl, a microtubule destabilizing drug. Benomyl-sensitive growth of wild-type cells required mono- and dimethylation of H3K4 and Pho23, a PHD-containing subunit of the Rpd3L complex. Δset1 and Δpho23 deletions suppressed defects associated with ipl1-2 aurora kinase mutant, an integral component of the spindle assembly checkpoint during mitosis. Benomyl resistance of Δset1 strains was accompanied by deregulation of all four tubulin genes and the phenotype was suppressed by tub2-423 and Δtub3 mutations, establishing a genetic link between H3K4 methylation and microtubule function. Most interestingly, sine wave fitting and clustering of transcript abundance time series in synchronized cells revealed a requirement for Set1 for proper cell-cycle-dependent gene expression and Δset1 cells displayed delayed entry into S phase. Disruption of G1/S regulation in Δmbp1 and Δswi4 transcription factor mutants duplicated both benomyl resistance and suppression of ipl1-2 as was observed with Δset1 Taken together our results support a role for H3K4 methylation in the coordination of cell-cycle progression and proper assembly of the mitotic spindle during mitosis.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28049706</PMID><DateCreated><Year>2017</Year><Month>01</Month><Day>04</Day></DateCreated><DateCompleted><Year>2017</Year><Month>06</Month><Day>13</Day></DateCompleted><DateRevised><Year>2017</Year><Month>06</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1943-2631</ISSN><JournalIssue CitedMedium="Internet"><Volume>205</Volume><Issue>1</Issue><PubDate><Year>2017</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Genetics</Title><ISOAbbreviation>Genetics</ISOAbbreviation></Journal><ArticleTitle>Coordination of Cell Cycle Progression and Mitotic Spindle Assembly Involves Histone H3 Lysine 4 Methylation by Set1/COMPASS.</ArticleTitle><Pagination><MedlinePgn>185-199</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1534/genetics.116.194852</ELocationID><Abstract><AbstractText>Methylation of histone H3 lysine 4 (H3K4) by Set1 complex/COMPASS is a hallmark of eukaryotic chromatin, but it remains poorly understood how this post-translational modification contributes to the regulation of biological processes like the cell cycle. Here, we report a H3K4 methylation-dependent pathway in Saccharomyces cerevisiae that governs toxicity toward benomyl, a microtubule destabilizing drug. Benomyl-sensitive growth of wild-type cells required mono- and dimethylation of H3K4 and Pho23, a PHD-containing subunit of the Rpd3L complex. Δset1 and Δpho23 deletions suppressed defects associated with ipl1-2 aurora kinase mutant, an integral component of the spindle assembly checkpoint during mitosis. Benomyl resistance of Δset1 strains was accompanied by deregulation of all four tubulin genes and the phenotype was suppressed by tub2-423 and Δtub3 mutations, establishing a genetic link between H3K4 methylation and microtubule function. Most interestingly, sine wave fitting and clustering of transcript abundance time series in synchronized cells revealed a requirement for Set1 for proper cell-cycle-dependent gene expression and Δset1 cells displayed delayed entry into S phase. Disruption of G1/S regulation in Δmbp1 and Δswi4 transcription factor mutants duplicated both benomyl resistance and suppression of ipl1-2 as was observed with Δset1 Taken together our results support a role for H3K4 methylation in the coordination of cell-cycle progression and proper assembly of the mitotic spindle during mitosis.</AbstractText><CopyrightInformation>Copyright © 2017 by the Genetics Society of America.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Beilharz</LastName><ForeName>Traude H</ForeName><Initials>TH</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-8942-9502</Identifier><AffiliationInfo><Affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Harrison</LastName><ForeName>Paul F</ForeName><Initials>PF</Initials><AffiliationInfo><Affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Monash Bioinformatics Platform, Monash University, Melbourne, Victoria 3800, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Miles</LastName><ForeName>Douglas Maya</ForeName><Initials>DM</Initials><AffiliationInfo><Affiliation>Marseille Cancer Research Center, U1068 Inserm, UMR7258 CNRS, Aix Marseille University, Institut Paoli-Calmettes, F-13009 Marseille, France. Equipe Labellisée Ligue.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>See</LastName><ForeName>Michael Ming</ForeName><Initials>MM</Initials><AffiliationInfo><Affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Le</LastName><ForeName>Uyen Minh Merry</ForeName><Initials>UM</Initials><AffiliationInfo><Affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kalanon</LastName><ForeName>Ming</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Centre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, Victoria 3125, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Curtis</LastName><ForeName>Melissa Jane</ForeName><Initials>MJ</Initials><AffiliationInfo><Affiliation>Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hasan</LastName><ForeName>Qambar</ForeName><Initials>Q</Initials><AffiliationInfo><Affiliation>Centre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, Victoria 3125, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Saksouk</LastName><ForeName>Julie</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Institute of Human Genetics, UPR 1142, CNRS, 34396 Montpellier, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Margaritis</LastName><ForeName>Thanasis</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Molecular Cancer Research, University Medical Center Utrecht-Princess Máxima Center for Pediatric Oncology, 3584 Utrecht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Holstege</LastName><ForeName>Frank</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Molecular Cancer Research, University Medical Center Utrecht-Princess Máxima Center for Pediatric Oncology, 3584 Utrecht, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Geli</LastName><ForeName>Vincent</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Marseille Cancer Research Center, U1068 Inserm, UMR7258 CNRS, Aix Marseille University, Institut Paoli-Calmettes, F-13009 Marseille, France. Equipe Labellisée Ligue Bernhard.Dichtl@deakin.edu.au vincent.geli@inserm.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dichtl</LastName><ForeName>Bernhard</ForeName><Initials>B</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-5514-4982</Identifier><AffiliationInfo><Affiliation>Centre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, Victoria 3125, Australia Bernhard.Dichtl@deakin.edu.au vincent.geli@inserm.fr.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>11</Month><Day>14</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Genetics</MedlineTA><NlmUniqueID>0374636</NlmUniqueID><ISSNLinking>0016-6731</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D002843">Chromatin</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D004268">DNA-Binding Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D006657">Histones</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D029701">Saccharomyces cerevisiae Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014157">Transcription Factors</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 2.1.1.43</RegistryNumber><NameOfSubstance UI="D011495">Histone-Lysine N-Methyltransferase</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 2.1.1.43</RegistryNumber><NameOfSubstance UI="C411250">SET1 protein, S cerevisiae</NameOfSubstance></Chemical><Chemical><RegistryNumber>K3Z4F929H6</RegistryNumber><NameOfSubstance UI="D008239">Lysine</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Genetics. 2005 Sep;171(1):49-61</RefSource><PMID Version="1">15965243</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Cell. 2003 Mar;11(3):709-19</RefSource><PMID Version="1">12667453</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Cell Biol. 1990 Oct;10(10):5295-304</RefSource><PMID Version="1">2204812</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2086-91</RefSource><PMID Version="1">17284592</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Rev Mol Cell Biol. 2007 May;8(5):379-93</RefSource><PMID Version="1">17426725</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Genes Dev. 2009 Apr 15;23 (8):951-62</RefSource><PMID Version="1">19346402</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nature. 2002 Jul 4;418(6893):104-8</RefSource><PMID Version="1">12077605</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 2005 Nov 18;123(4):593-605</RefSource><PMID Version="1">16286008</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Genome Biol. 2010;11(3):R24</RefSource><PMID Version="1">20193063</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 2001 Feb 9;104(3):377-86</RefSource><PMID Version="1">11239395</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 2005 Nov 18;123(4):581-92</RefSource><PMID Version="1">16286007</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 2005 Aug 26;122(4):517-27</RefSource><PMID Version="1">16122420</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Cell Biol. 1988 Jun;106(6):1997-2010</RefSource><PMID Version="1">3290223</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell Cycle. 2009 Jan 15;8(2):214-7</RefSource><PMID Version="1">19158488</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 2005 Sep 9;122(5):723-34</RefSource><PMID Version="1">16143104</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Methods Mol Biol. 2015;1300:105-12</RefSource><PMID Version="1">25916708</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16609-14</RefSource><PMID Version="1">17925448</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Biol Cell. 1997 Dec;8(12):2421-36</RefSource><PMID Version="1">9398665</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Biol Chem. 2001 Jun 29;276(26):24068-74</RefSource><PMID Version="1">11306585</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>EMBO J. 2004 May 5;23(9):1957-67</RefSource><PMID Version="1">15071505</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 1991 Aug 9;66(3):519-31</RefSource><PMID Version="1">1651172</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nucleic Acids Res. 2014 Apr;42(7):4348-62</RefSource><PMID Version="1">24497191</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Rev Mol Cell Biol. 2014 Nov;15(11):703-8</RefSource><PMID Version="1">25315270</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Biol. 2012;10(7):e1001369</RefSource><PMID Version="1">22912562</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Cell. 2005 Sep 16;19(6):849-56</RefSource><PMID Version="1">16168379</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):E1016-25</RefSource><PMID Version="1">23382196</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Cell Biol. 1995 Dec;131(6 Pt 2):1775-88</RefSource><PMID Version="1">8557744</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):12902-7</RefSource><PMID Version="1">11687631</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Cell Biol. 1986 Nov;6(11):3722-33</RefSource><PMID Version="1">3540600</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 1983 May;33(1):211-9</RefSource><PMID Version="1">6380751</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Biochemistry. 1981 Jun 9;20(12):3629-33</RefSource><PMID Version="1">7020758</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):90-4</RefSource><PMID Version="1">11752412</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2007 Apr 3;104(14 ):5836-41</RefSource><PMID Version="1">17389396</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Cell Biol. 1982 Sep;2(9):1064-79</RefSource><PMID Version="1">6757720</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nature. 2004 Mar 4;428(6978):93-7</RefSource><PMID Version="1">14961024</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 2007 Feb 23;128(4):693-705</RefSource><PMID Version="1">17320507</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>EMBO J. 2009 Jun 17;28(12):1697-707</RefSource><PMID Version="1">19407817</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Biol Chem. 2003 Sep 5;278(36):33625-8</RefSource><PMID Version="1">12876293</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Cell. 2006 Aug;23 (4):483-96</RefSource><PMID Version="1">16916637</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nucleic Acids Res. 2007;35(7):2428-39</RefSource><PMID Version="1">17392337</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Genet. 2011 Mar;7(3):e1001354</RefSource><PMID Version="1">21483810</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8695-700</RefSource><PMID Version="1">12060701</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 2005 Jun 3;121(5):725-37</RefSource><PMID Version="1">15935759</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Cell Biol. 1996 Jul;134(2):443-54</RefSource><PMID Version="1">8707828</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>RNA. 2012 Jun;18(6):1289-95</RefSource><PMID Version="1">22543866</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Biochem Cell Biol. 2006 Aug;84(4):536-48</RefSource><PMID Version="1">16936826</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>RNA. 2015 Aug;21(8):1502-10</RefSource><PMID Version="1">26092945</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Cell. 2003 Mar;11(3):721-9</RefSource><PMID Version="1">12667454</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 2002 Feb 8;108(3):317-29</RefSource><PMID Version="1">11853667</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Biol Chem. 2007 Jan 26;282(4):2450-5</RefSource><PMID Version="1">17142463</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 2011 Sep 2;146(5):709-19</RefSource><PMID Version="1">21884933</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nature. 2002 Sep 26;419(6905):407-11</RefSource><PMID Version="1">12353038</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>EMBO Rep. 2003 Jan;4(1):94-9</RefSource><PMID Version="1">12524528</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Cell Biol. 1988 Oct;107(4):1409-26</RefSource><PMID Version="1">3049620</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Genes Dev. 2016 May 15;30(10 ):1187-97</RefSource><PMID Version="1">27198228</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Cell Biol. 2006 Jan;8(1):78-83</RefSource><PMID Version="1">16327780</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>RNA. 2004 Jun;10(6):965-77</RefSource><PMID Version="1">15146080</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cell. 2009 Apr 17;137(2):259-72</RefSource><PMID Version="1">19379692</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Mol Biol. 2005 Oct 28;353(3):477-84</RefSource><PMID Version="1">16185711</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Syst Biol. 2014 Jun 21;10:732</RefSource><PMID Version="1">24952590</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>EMBO J. 2001 Dec 17;20(24):7137-48</RefSource><PMID Version="1">11742990</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Rev Mol Cell Biol. 2013 Aug;14(8):518-28</RefSource><PMID Version="1">23877564</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Cell. 2007 Jul 6;27(1):107-19</RefSource><PMID Version="1">17612494</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Biol Cell. 1994 Jan;5(1):29-43</RefSource><PMID Version="1">8186463</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Genes Dev. 2001 Dec 15;15(24):3286-95</RefSource><PMID Version="1">11751634</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Yeast. 2003 Jul 15;20(9):827-35</RefSource><PMID Version="1">12845608</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Genet. 2012 Sep;8(9):e1002952</RefSource><PMID Version="1">23028359</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D002843" MajorTopicYN="N">Chromatin</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004268" MajorTopicYN="N">DNA-Binding Proteins</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011495" MajorTopicYN="N">Histone-Lysine N-Methyltransferase</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006657" MajorTopicYN="N">Histones</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008239" MajorTopicYN="N">Lysine</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D059566" MajorTopicYN="N">M Phase Cell Cycle Checkpoints</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008745" MajorTopicYN="N">Methylation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008938" MajorTopicYN="N">Mitosis</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011499" MajorTopicYN="N">Protein Processing, Post-Translational</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012441" MajorTopicYN="N">Saccharomyces cerevisiae</DescriptorName><QualifierName UI="Q000166" MajorTopicYN="N">cytology</QualifierName><QualifierName UI="Q000201" MajorTopicYN="N">enzymology</QualifierName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D029701" MajorTopicYN="N">Saccharomyces cerevisiae Proteins</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008941" MajorTopicYN="N">Spindle Apparatus</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014157" MajorTopicYN="N">Transcription Factors</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D054875" MajorTopicYN="N">Ubiquitination</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">aurora kinase</Keyword><Keyword MajorTopicYN="N">benomyl</Keyword><Keyword MajorTopicYN="N">cell cycle</Keyword><Keyword MajorTopicYN="N">gene expression</Keyword><Keyword MajorTopicYN="N">histone methylation</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>08</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>11</Month><Day>07</Day></PubMedPubDate><PubMedPubDate PubStatus="pmc-release"><Year>2018</Year><Month>01</Month><Day>01</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>1</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>1</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>6</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28049706</ArticleId><ArticleId IdType="pii">genetics.116.194852</ArticleId><ArticleId IdType="doi">10.1534/genetics.116.194852</ArticleId><ArticleId IdType="pmc">PMC5223502</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001235 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 001235 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:28049706
|texte= Coordination of Cell Cycle Progression and Mitotic Spindle Assembly Involves Histone H3 Lysine 4 Methylation by Set1/COMPASS.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:28049706" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |