Parsing the life-shortening effects of dietary protein: effects of individual amino acids.
Identifieur interne : 001234 ( PubMed/Corpus ); précédent : 001233; suivant : 001235Parsing the life-shortening effects of dietary protein: effects of individual amino acids.
Auteurs : Sara Arganda ; Sofia Bouchebti ; Sepideh Bazazi ; Sophie Le Hesran ; Camille Puga ; Gérard Latil ; Stephen J. Simpson ; Audrey DussutourSource :
- Proceedings. Biological sciences [ 1471-2954 ] ; 2017.
Abstract
High-protein diets shorten lifespan in many organisms. Is it because protein digestion is energetically costly or because the final products (the amino acids) are harmful? To answer this question while circumventing the life-history trade-off between reproduction and longevity, we fed sterile ant workers on diets based on whole proteins or free amino acids. We found that (i) free amino acids shortened lifespan even more than proteins; (ii) the higher the amino acid-to-carbohydrate ratio, the shorter ants lived and the lower their lipid reserves; (iii) for the same amino acid-to-carbohydrate ratio, ants eating free amino acids had more lipid reserves than those eating whole proteins; and (iv) on whole protein diets, ants seem to regulate food intake by prioritizing sugar, while on free amino acid diets, they seem to prioritize amino acids. To test the effect of the amino acid profile, we tested diets containing proportions of each amino acid that matched the ant's exome; surprisingly, longevity was unaffected by this change. We further tested diets with all amino acids under-represented except one, finding that methionine, serine, threonine and phenylalanine are especially harmful. All together, our results show certain amino acids are key elements behind the high-protein diet reduction in lifespan.
DOI: 10.1098/rspb.2016.2052
PubMed: 28053059
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pubmed:28053059Le document en format XML
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<front><div type="abstract" xml:lang="en">High-protein diets shorten lifespan in many organisms. Is it because protein digestion is energetically costly or because the final products (the amino acids) are harmful? To answer this question while circumventing the life-history trade-off between reproduction and longevity, we fed sterile ant workers on diets based on whole proteins or free amino acids. We found that (i) free amino acids shortened lifespan even more than proteins; (ii) the higher the amino acid-to-carbohydrate ratio, the shorter ants lived and the lower their lipid reserves; (iii) for the same amino acid-to-carbohydrate ratio, ants eating free amino acids had more lipid reserves than those eating whole proteins; and (iv) on whole protein diets, ants seem to regulate food intake by prioritizing sugar, while on free amino acid diets, they seem to prioritize amino acids. To test the effect of the amino acid profile, we tested diets containing proportions of each amino acid that matched the ant's exome; surprisingly, longevity was unaffected by this change. We further tested diets with all amino acids under-represented except one, finding that methionine, serine, threonine and phenylalanine are especially harmful. All together, our results show certain amino acids are key elements behind the high-protein diet reduction in lifespan.</div>
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<Abstract><AbstractText>High-protein diets shorten lifespan in many organisms. Is it because protein digestion is energetically costly or because the final products (the amino acids) are harmful? To answer this question while circumventing the life-history trade-off between reproduction and longevity, we fed sterile ant workers on diets based on whole proteins or free amino acids. We found that (i) free amino acids shortened lifespan even more than proteins; (ii) the higher the amino acid-to-carbohydrate ratio, the shorter ants lived and the lower their lipid reserves; (iii) for the same amino acid-to-carbohydrate ratio, ants eating free amino acids had more lipid reserves than those eating whole proteins; and (iv) on whole protein diets, ants seem to regulate food intake by prioritizing sugar, while on free amino acid diets, they seem to prioritize amino acids. To test the effect of the amino acid profile, we tested diets containing proportions of each amino acid that matched the ant's exome; surprisingly, longevity was unaffected by this change. We further tested diets with all amino acids under-represented except one, finding that methionine, serine, threonine and phenylalanine are especially harmful. All together, our results show certain amino acids are key elements behind the high-protein diet reduction in lifespan.</AbstractText>
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<CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>J Exp Biol. 1995 Feb;198(Pt 2):273-81</RefSource>
<PMID Version="1">7699310</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Biochim Biophys Acta. 2002 Apr 24;1586(3):344-52</RefSource>
<PMID Version="1">11997085</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Cell. 2015 Mar 26;161(1):106-18</RefSource>
<PMID Version="1">25815989</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Nature. 2009 Dec 24;462(7276):1061-4</RefSource>
<PMID Version="1">19956092</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS Genet. 2014 Feb 06;10(2):e1004113</RefSource>
<PMID Version="1">24516402</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Proc Biol Sci. 2012 Jun 22;279(1737):2402-8</RefSource>
<PMID Version="1">22357267</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Exp Biol. 2016 Mar;219(Pt 6):824-33</RefSource>
<PMID Version="1">26985052</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3481-6</RefSource>
<PMID Version="1">25733862</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21236-41</RefSource>
<PMID Version="1">19948964</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Am Coll Nutr. 2004 Oct;23(5):373-85</RefSource>
<PMID Version="1">15466943</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2004 May 25;101(21):7999-8004</RefSource>
<PMID Version="1">15141092</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Nutr. 1971 Sep;101(9):1117-25</RefSource>
<PMID Version="1">5096135</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Appetite. 2003 Oct;41(2):123-40</RefSource>
<PMID Version="1">14550310</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Curr Biol. 2009 May 12;19(9):740-4</RefSource>
<PMID Version="1">19345104</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Int J Obes Relat Metab Disord. 1999 Mar;23(3):287-92</RefSource>
<PMID Version="1">10193874</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Annu Rev Entomol. 2006;51:113-35</RefSource>
<PMID Version="1">16332206</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Int J Cancer. 2013 Mar 1;132(5):1213-21</RefSource>
<PMID Version="1">22858865</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Science. 2011 Jul 1;333(6038):101-4</RefSource>
<PMID Version="1">21596954</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Nutr. 1993 Feb;123(2):269-74</RefSource>
<PMID Version="1">8429371</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Cell Mol Life Sci. 2016 Mar;73(6):1237-52</RefSource>
<PMID Version="1">26718486</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Aging (Albany NY). 2009 Oct 22;1(10):875-80</RefSource>
<PMID Version="1">20157561</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2014 May 15;9(5):e97729</RefSource>
<PMID Version="1">24830393</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Age (Dordr). 2007 Mar;29(1):29-39</RefSource>
<PMID Version="1">19424828</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Insect Physiol. 2014 Dec;71:78-86</RefSource>
<PMID Version="1">25450562</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>BMC Genet. 2015 Feb 03;16:8</RefSource>
<PMID Version="1">25643626</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Physiol. 1998 Sep;275(3 Pt 1):C857-69</RefSource>
<PMID Version="1">9730971</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Aging (Albany NY). 2014 May;6(5):390-8</RefSource>
<PMID Version="1">24861087</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5673-8</RefSource>
<PMID Version="1">21282631</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Curr Biol. 2004 Jun 22;14(12):1065-79</RefSource>
<PMID Version="1">15202999</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Nature. 2004 Dec 23;432(7020):1024-7</RefSource>
<PMID Version="1">15616562</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Nat Commun. 2014 Apr 07;5:3592</RefSource>
<PMID Version="1">24710037</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Nutr. 1953 Sep;51(1):71-84</RefSource>
<PMID Version="1">13097227</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>FASEB J. 1994 Dec;8(15):1302-7</RefSource>
<PMID Version="1">8001743</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Cell Metab. 2011 Aug 3;14(2):154-60</RefSource>
<PMID Version="1">21803286</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Insect Physiol. 2007 Nov;53(11):1101-11</RefSource>
<PMID Version="1">17681527</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Comp Biochem Physiol B Biochem Mol Biol. 1995 Sep;112(1):15-9</RefSource>
<PMID Version="1">7584843</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2498-503</RefSource>
<PMID Version="1">18268352</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2013 Nov 07;8(11):e79319</RefSource>
<PMID Version="1">24244480</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Insect Physiol. 2014 Oct;69:19-26</RefSource>
<PMID Version="1">24751909</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Exp Biol. 2008 Jul;211(Pt 14):2224-32</RefSource>
<PMID Version="1">18587116</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Insect Physiol. 2012 Apr;58(4):433-49</RefSource>
<PMID Version="1">22230793</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2014 Nov 13;9(11):e112801</RefSource>
<PMID Version="1">25392989</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
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