Neandertal and Denisovan DNA from Pleistocene sediments.
Identifieur interne : 000747 ( PubMed/Checkpoint ); précédent : 000746; suivant : 000748Neandertal and Denisovan DNA from Pleistocene sediments.
Auteurs : Viviane Slon [Allemagne] ; Charlotte Hopfe [Allemagne] ; Clemens L. Wei [Allemagne] ; Fabrizio Mafessoni [Allemagne] ; Marco De La Rasilla [Espagne] ; Carles Lalueza-Fox [Espagne] ; Antonio Rosas [Espagne] ; Marie Soressi [Pays-Bas] ; Monika V. Knul [Royaume-Uni] ; Rebecca Miller [Belgique] ; John R. Stewart [Royaume-Uni] ; Anatoly P. Derevianko [Russie] ; Zenobia Jacobs [Australie] ; Bo Li [Australie] ; Richard G. Roberts [Australie] ; Michael V. Shunkov [Russie] ; Henry De Lumley [France] ; Christian Perrenoud [France] ; Ivan Guši [Croatie] ; Željko Ku An [Croatie] ; Pavao Rudan [Croatie] ; Ayinuer Aximu-Petri [Allemagne] ; Elena Essel [Allemagne] ; Sarah Nagel [Allemagne] ; Birgit Nickel [Allemagne] ; Anna Schmidt [Allemagne] ; Kay Prüfer [Allemagne] ; Janet Kelso [Allemagne] ; Hernán A. Burbano [Allemagne] ; Svante P Bo [Allemagne] ; Matthias Meyer [Allemagne]Source :
- Science (New York, N.Y.) [ 1095-9203 ] ; 2017.
Abstract
Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.
DOI: 10.1126/science.aam9695
PubMed: 28450384
Affiliations:
- Allemagne, Australie, Belgique, Croatie, Espagne, France, Pays-Bas, Royaume-Uni, Russie
- Catalogne, Communauté de Madrid, District de Leipzig, Hollande-Méridionale, Province de Liège, Saxe (Land)
- Barcelone, Leipzig, Leyde, Liège, Madrid
- Université de Liège
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Zagreb</wicri:regionArea><wicri:noRegion>10000 Zagreb</wicri:noRegion></affiliation></author><author><name sortKey="Aximu Petri, Ayinuer" sort="Aximu Petri, Ayinuer" uniqKey="Aximu Petri A" first="Ayinuer" last="Aximu-Petri">Ayinuer Aximu-Petri</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Essel, Elena" sort="Essel, Elena" uniqKey="Essel E" first="Elena" last="Essel">Elena Essel</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Nagel, Sarah" sort="Nagel, Sarah" uniqKey="Nagel S" first="Sarah" last="Nagel">Sarah Nagel</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Nickel, Birgit" sort="Nickel, Birgit" uniqKey="Nickel B" first="Birgit" last="Nickel">Birgit Nickel</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Schmidt, Anna" sort="Schmidt, Anna" uniqKey="Schmidt A" first="Anna" last="Schmidt">Anna Schmidt</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Prufer, Kay" sort="Prufer, Kay" uniqKey="Prufer K" first="Kay" last="Prüfer">Kay Prüfer</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Kelso, Janet" sort="Kelso, Janet" uniqKey="Kelso J" first="Janet" last="Kelso">Janet Kelso</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Burbano, Hernan A" sort="Burbano, Hernan A" uniqKey="Burbano H" first="Hernán A" last="Burbano">Hernán A. Burbano</name><affiliation wicri:level="1"><nlm:affiliation>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen</wicri:regionArea><wicri:noRegion>72076 Tübingen</wicri:noRegion><wicri:noRegion>72076 Tübingen</wicri:noRegion><wicri:noRegion>72076 Tübingen</wicri:noRegion></affiliation></author><author><name sortKey="P Bo, Svante" sort="P Bo, Svante" uniqKey="P Bo S" first="Svante" last="P Bo">Svante P Bo</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Meyer, Matthias" sort="Meyer, Matthias" uniqKey="Meyer M" first="Matthias" last="Meyer">Matthias Meyer</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany. viviane_slon@eva.mpg.de mmeyer@eva.mpg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28450384</idno><idno type="pmid">28450384</idno><idno type="doi">10.1126/science.aam9695</idno><idno type="wicri:Area/PubMed/Corpus">000D00</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000D00</idno><idno type="wicri:Area/PubMed/Curation">000C97</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000C97</idno><idno type="wicri:Area/PubMed/Checkpoint">000C97</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000C97</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Neandertal and Denisovan DNA from Pleistocene sediments.</title><author><name sortKey="Slon, Viviane" sort="Slon, Viviane" uniqKey="Slon V" first="Viviane" last="Slon">Viviane Slon</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany. viviane_slon@eva.mpg.de mmeyer@eva.mpg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Hopfe, Charlotte" sort="Hopfe, Charlotte" uniqKey="Hopfe C" first="Charlotte" last="Hopfe">Charlotte Hopfe</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Wei, Clemens L" sort="Wei, Clemens L" uniqKey="Wei C" first="Clemens L" last="Wei">Clemens L. Wei</name><affiliation wicri:level="1"><nlm:affiliation>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen</wicri:regionArea><wicri:noRegion>72076 Tübingen</wicri:noRegion><wicri:noRegion>72076 Tübingen</wicri:noRegion><wicri:noRegion>72076 Tübingen</wicri:noRegion></affiliation></author><author><name sortKey="Mafessoni, Fabrizio" sort="Mafessoni, Fabrizio" uniqKey="Mafessoni F" first="Fabrizio" last="Mafessoni">Fabrizio Mafessoni</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="De La Rasilla, Marco" sort="De La Rasilla, Marco" uniqKey="De La Rasilla M" first="Marco" last="De La Rasilla">Marco De La Rasilla</name><affiliation wicri:level="1"><nlm:affiliation>Área de Prehistoria, Department of History, Universidad de Oviedo, Calle Teniente Alfonso Martínez s/n, 33011 Oviedo, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Área de Prehistoria, Department of History, Universidad de Oviedo, Calle Teniente Alfonso Martínez s/n, 33011 Oviedo</wicri:regionArea><wicri:noRegion>33011 Oviedo</wicri:noRegion></affiliation></author><author><name sortKey="Lalueza Fox, Carles" sort="Lalueza Fox, Carles" uniqKey="Lalueza Fox C" first="Carles" last="Lalueza-Fox">Carles Lalueza-Fox</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Evolutionary Biology, Universitat Pompeu Fabra-Consejo Superior de Investigaciones Científicas (UPF-CSIC), 08003 Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Institute of Evolutionary Biology, Universitat Pompeu Fabra-Consejo Superior de Investigaciones Científicas (UPF-CSIC), 08003 Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Rosas, Antonio" sort="Rosas, Antonio" uniqKey="Rosas A" first="Antonio" last="Rosas">Antonio Rosas</name><affiliation wicri:level="1"><nlm:affiliation>Departamento de Paleobiología, Museo Nacional de Ciencias Naturales, CSIC, 28006 Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Departamento de Paleobiología, Museo Nacional de Ciencias Naturales, CSIC, 28006 Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Soressi, Marie" sort="Soressi, Marie" uniqKey="Soressi M" first="Marie" last="Soressi">Marie Soressi</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Archaeology, Leiden University, 2333CC Leiden, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Faculty of Archaeology, Leiden University, 2333CC Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Knul, Monika V" sort="Knul, Monika V" uniqKey="Knul M" first="Monika V" last="Knul">Monika V. Knul</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Science and Technology, Bournemouth University, Poole, Dorset, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Faculty of Science and Technology, Bournemouth University, Poole, Dorset</wicri:regionArea><wicri:noRegion>Dorset</wicri:noRegion></affiliation></author><author><name sortKey="Miller, Rebecca" sort="Miller, Rebecca" uniqKey="Miller R" first="Rebecca" last="Miller">Rebecca Miller</name><affiliation wicri:level="4"><nlm:affiliation>Service de Préhistoire, Université de Liège, 4000 Liège, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Service de Préhistoire, Université de Liège, 4000 Liège</wicri:regionArea><placeName><region type="province" nuts="2">Province de Liège</region><settlement type="city">Liège</settlement><settlement type="city">Liège</settlement></placeName><orgName type="university">Université de Liège</orgName></affiliation></author><author><name sortKey="Stewart, John R" sort="Stewart, John R" uniqKey="Stewart J" first="John R" last="Stewart">John R. Stewart</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Science and Technology, Bournemouth University, Poole, Dorset, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Faculty of Science and Technology, Bournemouth University, Poole, Dorset</wicri:regionArea><wicri:noRegion>Dorset</wicri:noRegion></affiliation></author><author><name sortKey="Derevianko, Anatoly P" sort="Derevianko, Anatoly P" uniqKey="Derevianko A" first="Anatoly P" last="Derevianko">Anatoly P. Derevianko</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk, RU-630090, Russia.</nlm:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Institute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk, RU-630090</wicri:regionArea><wicri:noRegion>RU-630090</wicri:noRegion></affiliation></author><author><name sortKey="Jacobs, Zenobia" sort="Jacobs, Zenobia" uniqKey="Jacobs Z" first="Zenobia" last="Jacobs">Zenobia Jacobs</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522</wicri:regionArea><wicri:noRegion>New South Wales 2522</wicri:noRegion></affiliation></author><author><name sortKey="Li, Bo" sort="Li, Bo" uniqKey="Li B" first="Bo" last="Li">Bo Li</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522</wicri:regionArea><wicri:noRegion>New South Wales 2522</wicri:noRegion></affiliation></author><author><name sortKey="Roberts, Richard G" sort="Roberts, Richard G" uniqKey="Roberts R" first="Richard G" last="Roberts">Richard G. Roberts</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522</wicri:regionArea><wicri:noRegion>New South Wales 2522</wicri:noRegion></affiliation></author><author><name sortKey="Shunkov, Michael V" sort="Shunkov, Michael V" uniqKey="Shunkov M" first="Michael V" last="Shunkov">Michael V. Shunkov</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk, RU-630090, Russia.</nlm:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Institute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk, RU-630090</wicri:regionArea><wicri:noRegion>RU-630090</wicri:noRegion></affiliation></author><author><name sortKey="De Lumley, Henry" sort="De Lumley, Henry" uniqKey="De Lumley H" first="Henry" last="De Lumley">Henry De Lumley</name><affiliation wicri:level="1"><nlm:affiliation>Centre Européen de Recherches Préhistoriques de Tautavel, 66720 Tautavel, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre Européen de Recherches Préhistoriques de Tautavel, 66720 Tautavel</wicri:regionArea><wicri:noRegion>66720 Tautavel</wicri:noRegion><wicri:noRegion>66720 Tautavel</wicri:noRegion></affiliation></author><author><name sortKey="Perrenoud, Christian" sort="Perrenoud, Christian" uniqKey="Perrenoud C" first="Christian" last="Perrenoud">Christian Perrenoud</name><affiliation wicri:level="1"><nlm:affiliation>Centre Européen de Recherches Préhistoriques de Tautavel, 66720 Tautavel, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre Européen de Recherches Préhistoriques de Tautavel, 66720 Tautavel</wicri:regionArea><wicri:noRegion>66720 Tautavel</wicri:noRegion><wicri:noRegion>66720 Tautavel</wicri:noRegion></affiliation></author><author><name sortKey="Gusi, Ivan" sort="Gusi, Ivan" uniqKey="Gusi I" first="Ivan" last="Guši">Ivan Guši</name><affiliation wicri:level="1"><nlm:affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb</wicri:regionArea><wicri:noRegion>10000 Zagreb</wicri:noRegion></affiliation></author><author><name sortKey="Ku An, Zeljko" sort="Ku An, Zeljko" uniqKey="Ku An Z" first="Željko" last="Ku An">Željko Ku An</name><affiliation wicri:level="1"><nlm:affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb</wicri:regionArea><wicri:noRegion>10000 Zagreb</wicri:noRegion></affiliation></author><author><name sortKey="Rudan, Pavao" sort="Rudan, Pavao" uniqKey="Rudan P" first="Pavao" last="Rudan">Pavao Rudan</name><affiliation wicri:level="1"><nlm:affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</nlm:affiliation><country xml:lang="fr">Croatie</country><wicri:regionArea>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb</wicri:regionArea><wicri:noRegion>10000 Zagreb</wicri:noRegion></affiliation></author><author><name sortKey="Aximu Petri, Ayinuer" sort="Aximu Petri, Ayinuer" uniqKey="Aximu Petri A" first="Ayinuer" last="Aximu-Petri">Ayinuer Aximu-Petri</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Essel, Elena" sort="Essel, Elena" uniqKey="Essel E" first="Elena" last="Essel">Elena Essel</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Nagel, Sarah" sort="Nagel, Sarah" uniqKey="Nagel S" first="Sarah" last="Nagel">Sarah Nagel</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Nickel, Birgit" sort="Nickel, Birgit" uniqKey="Nickel B" first="Birgit" last="Nickel">Birgit Nickel</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Schmidt, Anna" sort="Schmidt, Anna" uniqKey="Schmidt A" first="Anna" last="Schmidt">Anna Schmidt</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Prufer, Kay" sort="Prufer, Kay" uniqKey="Prufer K" first="Kay" last="Prüfer">Kay Prüfer</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Kelso, Janet" sort="Kelso, Janet" uniqKey="Kelso J" first="Janet" last="Kelso">Janet Kelso</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Burbano, Hernan A" sort="Burbano, Hernan A" uniqKey="Burbano H" first="Hernán A" last="Burbano">Hernán A. Burbano</name><affiliation wicri:level="1"><nlm:affiliation>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen</wicri:regionArea><wicri:noRegion>72076 Tübingen</wicri:noRegion><wicri:noRegion>72076 Tübingen</wicri:noRegion><wicri:noRegion>72076 Tübingen</wicri:noRegion></affiliation></author><author><name sortKey="P Bo, Svante" sort="P Bo, Svante" uniqKey="P Bo S" first="Svante" last="P Bo">Svante P Bo</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Meyer, Matthias" sort="Meyer, Matthias" uniqKey="Meyer M" first="Matthias" last="Meyer">Matthias Meyer</name><affiliation wicri:level="3"><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany. viviane_slon@eva.mpg.de mmeyer@eva.mpg.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author></analytic><series><title level="j">Science (New York, N.Y.)</title><idno type="eISSN">1095-9203</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">28450384</PMID><DateCreated><Year>2017</Year><Month>04</Month><Day>28</Day></DateCreated><DateRevised><Year>2017</Year><Month>10</Month><Day>12</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1095-9203</ISSN><JournalIssue CitedMedium="Internet"><Volume>356</Volume><Issue>6338</Issue><PubDate><Year>2017</Year><Month>05</Month><Day>12</Day></PubDate></JournalIssue><Title>Science (New York, N.Y.)</Title><ISOAbbreviation>Science</ISOAbbreviation></Journal><ArticleTitle>Neandertal and Denisovan DNA from Pleistocene sediments.</ArticleTitle><Pagination><MedlinePgn>605-608</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1126/science.aam9695</ELocationID><Abstract><AbstractText>Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.</AbstractText><CopyrightInformation>Copyright © 2017, American Association for the Advancement of Science.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Slon</LastName><ForeName>Viviane</ForeName><Initials>V</Initials><Identifier Source="ORCID">0000-0001-6485-7159</Identifier><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany. viviane_slon@eva.mpg.de mmeyer@eva.mpg.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hopfe</LastName><ForeName>Charlotte</ForeName><Initials>C</Initials><Identifier Source="ORCID">0000-0003-0662-081X</Identifier><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Weiß</LastName><ForeName>Clemens L</ForeName><Initials>CL</Initials><AffiliationInfo><Affiliation>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mafessoni</LastName><ForeName>Fabrizio</ForeName><Initials>F</Initials><Identifier Source="ORCID">0000-0003-4319-2076</Identifier><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de la Rasilla</LastName><ForeName>Marco</ForeName><Initials>M</Initials><Identifier Source="ORCID">0000-0002-5505-0625</Identifier><AffiliationInfo><Affiliation>Área de Prehistoria, Department of History, Universidad de Oviedo, Calle Teniente Alfonso Martínez s/n, 33011 Oviedo, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lalueza-Fox</LastName><ForeName>Carles</ForeName><Initials>C</Initials><Identifier Source="ORCID">0000-0002-1730-5914</Identifier><AffiliationInfo><Affiliation>Institute of Evolutionary Biology, Universitat Pompeu Fabra-Consejo Superior de Investigaciones Científicas (UPF-CSIC), 08003 Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rosas</LastName><ForeName>Antonio</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Departamento de Paleobiología, Museo Nacional de Ciencias Naturales, CSIC, 28006 Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Soressi</LastName><ForeName>Marie</ForeName><Initials>M</Initials><Identifier Source="ORCID">0000-0003-1733-7745</Identifier><AffiliationInfo><Affiliation>Faculty of Archaeology, Leiden University, 2333CC Leiden, Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Knul</LastName><ForeName>Monika V</ForeName><Initials>MV</Initials><Identifier Source="ORCID">0000-0002-0650-0992</Identifier><AffiliationInfo><Affiliation>Faculty of Science and Technology, Bournemouth University, Poole, Dorset, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Miller</LastName><ForeName>Rebecca</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Service de Préhistoire, Université de Liège, 4000 Liège, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stewart</LastName><ForeName>John R</ForeName><Initials>JR</Initials><AffiliationInfo><Affiliation>Faculty of Science and Technology, Bournemouth University, Poole, Dorset, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Derevianko</LastName><ForeName>Anatoly P</ForeName><Initials>AP</Initials><AffiliationInfo><Affiliation>Institute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk, RU-630090, Russia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Altai State University, Barnaul, RU-656049, Russia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jacobs</LastName><ForeName>Zenobia</ForeName><Initials>Z</Initials><Identifier Source="ORCID">0000-0001-5424-5837</Identifier><AffiliationInfo><Affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Australian Research Council (ARC) Centre of Excellence for Australian Biodiversity and Heritage, University of Wollongong, Wollongong, New South Wales 2522, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Bo</ForeName><Initials>B</Initials><Identifier Source="ORCID">0000-0003-4186-4828</Identifier><AffiliationInfo><Affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Roberts</LastName><ForeName>Richard G</ForeName><Initials>RG</Initials><Identifier Source="ORCID">0000-0002-0128-4119</Identifier><AffiliationInfo><Affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Australian Research Council (ARC) Centre of Excellence for Australian Biodiversity and Heritage, University of Wollongong, Wollongong, New South Wales 2522, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shunkov</LastName><ForeName>Michael V</ForeName><Initials>MV</Initials><AffiliationInfo><Affiliation>Institute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk, RU-630090, Russia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Novosibirsk National Research State University, Novosibirsk, RU-630090, Russia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Lumley</LastName><ForeName>Henry</ForeName><Initials>H</Initials><Identifier Source="ORCID">0000-0001-5442-1669</Identifier><AffiliationInfo><Affiliation>Centre Européen de Recherches Préhistoriques de Tautavel, 66720 Tautavel, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institut de Paléontologie Humaine, 75013 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Perrenoud</LastName><ForeName>Christian</ForeName><Initials>C</Initials><Identifier Source="ORCID">0000-0001-9704-1172</Identifier><AffiliationInfo><Affiliation>Centre Européen de Recherches Préhistoriques de Tautavel, 66720 Tautavel, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Muséum national d'Histoire naturelle, Département Homme et Environnement, UMR 7194 HNHP, 75013 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gušić</LastName><ForeName>Ivan</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kućan</LastName><ForeName>Željko</ForeName><Initials>Ž</Initials><AffiliationInfo><Affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rudan</LastName><ForeName>Pavao</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Aximu-Petri</LastName><ForeName>Ayinuer</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Essel</LastName><ForeName>Elena</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nagel</LastName><ForeName>Sarah</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nickel</LastName><ForeName>Birgit</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schmidt</LastName><ForeName>Anna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Prüfer</LastName><ForeName>Kay</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kelso</LastName><ForeName>Janet</ForeName><Initials>J</Initials><Identifier Source="ORCID">0000-0002-3618-322X</Identifier><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Burbano</LastName><ForeName>Hernán A</ForeName><Initials>HA</Initials><Identifier Source="ORCID">0000-0003-3433-719X</Identifier><AffiliationInfo><Affiliation>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pääbo</LastName><ForeName>Svante</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Meyer</LastName><ForeName>Matthias</ForeName><Initials>M</Initials><Identifier Source="ORCID">0000-0002-4760-558X</Identifier><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany. viviane_slon@eva.mpg.de mmeyer@eva.mpg.de.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><DataBankList CompleteYN="Y"><DataBank><DataBankName>Dryad</DataBankName><AccessionNumberList><AccessionNumber>m2dk7</AccessionNumber></AccessionNumberList></DataBank></DataBankList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>04</Month><Day>27</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Science</MedlineTA><NlmUniqueID>0404511</NlmUniqueID><ISSNLinking>0036-8075</ISSNLinking></MedlineJournalInfo></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>02</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>04</Month><Day>07</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>4</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>4</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>4</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28450384</ArticleId><ArticleId IdType="pii">science.aam9695</ArticleId><ArticleId IdType="doi">10.1126/science.aam9695</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Belgique</li><li>Croatie</li><li>Espagne</li><li>France</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Russie</li></country><region><li>Catalogne</li><li>Communauté de Madrid</li><li>District de Leipzig</li><li>Hollande-Méridionale</li><li>Province de Liège</li><li>Saxe (Land)</li></region><settlement><li>Barcelone</li><li>Leipzig</li><li>Leyde</li><li>Liège</li><li>Madrid</li></settlement><orgName><li>Université de Liège</li></orgName></list><tree><country name="Allemagne"><region name="Saxe (Land)"><name sortKey="Slon, Viviane" sort="Slon, Viviane" uniqKey="Slon V" first="Viviane" last="Slon">Viviane Slon</name></region><name sortKey="Aximu Petri, Ayinuer" sort="Aximu Petri, Ayinuer" uniqKey="Aximu Petri A" first="Ayinuer" 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Roberts</name></country><country name="France"><noRegion><name sortKey="De Lumley, Henry" sort="De Lumley, Henry" uniqKey="De Lumley H" first="Henry" last="De Lumley">Henry De Lumley</name></noRegion><name sortKey="Perrenoud, Christian" sort="Perrenoud, Christian" uniqKey="Perrenoud C" first="Christian" last="Perrenoud">Christian Perrenoud</name></country><country name="Croatie"><noRegion><name sortKey="Gusi, Ivan" sort="Gusi, Ivan" uniqKey="Gusi I" first="Ivan" last="Guši">Ivan Guši</name></noRegion><name sortKey="Ku An, Zeljko" sort="Ku An, Zeljko" uniqKey="Ku An Z" first="Željko" last="Ku An">Željko Ku An</name><name sortKey="Rudan, Pavao" sort="Rudan, Pavao" uniqKey="Rudan P" first="Pavao" last="Rudan">Pavao Rudan</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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