Neandertal and Denisovan DNA from Pleistocene sediments.
Identifieur interne : 000D00 ( PubMed/Corpus ); précédent : 000C99; suivant : 000D01Neandertal and Denisovan DNA from Pleistocene sediments.
Auteurs : Viviane Slon ; Charlotte Hopfe ; Clemens L. Wei ; Fabrizio Mafessoni ; Marco De La Rasilla ; Carles Lalueza-Fox ; Antonio Rosas ; Marie Soressi ; Monika V. Knul ; Rebecca Miller ; John R. Stewart ; Anatoly P. Derevianko ; Zenobia Jacobs ; Bo Li ; Richard G. Roberts ; Michael V. Shunkov ; Henry De Lumley ; Christian Perrenoud ; Ivan Guši ; Željko Ku An ; Pavao Rudan ; Ayinuer Aximu-Petri ; Elena Essel ; Sarah Nagel ; Birgit Nickel ; Anna Schmidt ; Kay Prüfer ; Janet Kelso ; Hernán A. Burbano ; Svante P Bo ; Matthias MeyerSource :
- Science (New York, N.Y.) [ 1095-9203 ] ; 2017.
Abstract
Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.
DOI: 10.1126/science.aam9695
PubMed: 28450384
Links to Exploration step
pubmed:28450384Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Neandertal and Denisovan DNA from Pleistocene sediments.</title><author><name sortKey="Slon, Viviane" sort="Slon, Viviane" uniqKey="Slon V" first="Viviane" last="Slon">Viviane Slon</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany. viviane_slon@eva.mpg.de mmeyer@eva.mpg.de.</nlm:affiliation></affiliation></author><author><name sortKey="Hopfe, Charlotte" sort="Hopfe, Charlotte" uniqKey="Hopfe C" first="Charlotte" last="Hopfe">Charlotte Hopfe</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Wei, Clemens L" sort="Wei, Clemens L" uniqKey="Wei C" first="Clemens L" last="Wei">Clemens L. Wei</name><affiliation><nlm:affiliation>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Mafessoni, Fabrizio" sort="Mafessoni, Fabrizio" uniqKey="Mafessoni F" first="Fabrizio" last="Mafessoni">Fabrizio Mafessoni</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="De La Rasilla, Marco" sort="De La Rasilla, Marco" uniqKey="De La Rasilla M" first="Marco" last="De La Rasilla">Marco De La Rasilla</name><affiliation><nlm:affiliation>Área de Prehistoria, Department of History, Universidad de Oviedo, Calle Teniente Alfonso Martínez s/n, 33011 Oviedo, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Lalueza Fox, Carles" sort="Lalueza Fox, Carles" uniqKey="Lalueza Fox C" first="Carles" last="Lalueza-Fox">Carles Lalueza-Fox</name><affiliation><nlm:affiliation>Institute of Evolutionary Biology, Universitat Pompeu Fabra-Consejo Superior de Investigaciones Científicas (UPF-CSIC), 08003 Barcelona, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Rosas, Antonio" sort="Rosas, Antonio" uniqKey="Rosas A" first="Antonio" last="Rosas">Antonio Rosas</name><affiliation><nlm:affiliation>Departamento de Paleobiología, Museo Nacional de Ciencias Naturales, CSIC, 28006 Madrid, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Soressi, Marie" sort="Soressi, Marie" uniqKey="Soressi M" first="Marie" last="Soressi">Marie Soressi</name><affiliation><nlm:affiliation>Faculty of Archaeology, Leiden University, 2333CC Leiden, Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Knul, Monika V" sort="Knul, Monika V" uniqKey="Knul M" first="Monika V" last="Knul">Monika V. Knul</name><affiliation><nlm:affiliation>Faculty of Science and Technology, Bournemouth University, Poole, Dorset, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Miller, Rebecca" sort="Miller, Rebecca" uniqKey="Miller R" first="Rebecca" last="Miller">Rebecca Miller</name><affiliation><nlm:affiliation>Service de Préhistoire, Université de Liège, 4000 Liège, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Stewart, John R" sort="Stewart, John R" uniqKey="Stewart J" first="John R" last="Stewart">John R. Stewart</name><affiliation><nlm:affiliation>Faculty of Science and Technology, Bournemouth University, Poole, Dorset, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Derevianko, Anatoly P" sort="Derevianko, Anatoly P" uniqKey="Derevianko A" first="Anatoly P" last="Derevianko">Anatoly P. Derevianko</name><affiliation><nlm:affiliation>Institute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk, RU-630090, Russia.</nlm:affiliation></affiliation></author><author><name sortKey="Jacobs, Zenobia" sort="Jacobs, Zenobia" uniqKey="Jacobs Z" first="Zenobia" last="Jacobs">Zenobia Jacobs</name><affiliation><nlm:affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Li, Bo" sort="Li, Bo" uniqKey="Li B" first="Bo" last="Li">Bo Li</name><affiliation><nlm:affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Roberts, Richard G" sort="Roberts, Richard G" uniqKey="Roberts R" first="Richard G" last="Roberts">Richard G. Roberts</name><affiliation><nlm:affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Shunkov, Michael V" sort="Shunkov, Michael V" uniqKey="Shunkov M" first="Michael V" last="Shunkov">Michael V. Shunkov</name><affiliation><nlm:affiliation>Institute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk, RU-630090, Russia.</nlm:affiliation></affiliation></author><author><name sortKey="De Lumley, Henry" sort="De Lumley, Henry" uniqKey="De Lumley H" first="Henry" last="De Lumley">Henry De Lumley</name><affiliation><nlm:affiliation>Centre Européen de Recherches Préhistoriques de Tautavel, 66720 Tautavel, France.</nlm:affiliation></affiliation></author><author><name sortKey="Perrenoud, Christian" sort="Perrenoud, Christian" uniqKey="Perrenoud C" first="Christian" last="Perrenoud">Christian Perrenoud</name><affiliation><nlm:affiliation>Centre Européen de Recherches Préhistoriques de Tautavel, 66720 Tautavel, France.</nlm:affiliation></affiliation></author><author><name sortKey="Gusi, Ivan" sort="Gusi, Ivan" uniqKey="Gusi I" first="Ivan" last="Guši">Ivan Guši</name><affiliation><nlm:affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Ku An, Zeljko" sort="Ku An, Zeljko" uniqKey="Ku An Z" first="Željko" last="Ku An">Željko Ku An</name><affiliation><nlm:affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Rudan, Pavao" sort="Rudan, Pavao" uniqKey="Rudan P" first="Pavao" last="Rudan">Pavao Rudan</name><affiliation><nlm:affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Aximu Petri, Ayinuer" sort="Aximu Petri, Ayinuer" uniqKey="Aximu Petri A" first="Ayinuer" last="Aximu-Petri">Ayinuer Aximu-Petri</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Essel, Elena" sort="Essel, Elena" uniqKey="Essel E" first="Elena" last="Essel">Elena Essel</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Nagel, Sarah" sort="Nagel, Sarah" uniqKey="Nagel S" first="Sarah" last="Nagel">Sarah Nagel</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Nickel, Birgit" sort="Nickel, Birgit" uniqKey="Nickel B" first="Birgit" last="Nickel">Birgit Nickel</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Schmidt, Anna" sort="Schmidt, Anna" uniqKey="Schmidt A" first="Anna" last="Schmidt">Anna Schmidt</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Prufer, Kay" sort="Prufer, Kay" uniqKey="Prufer K" first="Kay" last="Prüfer">Kay Prüfer</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Kelso, Janet" sort="Kelso, Janet" uniqKey="Kelso J" first="Janet" last="Kelso">Janet Kelso</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Burbano, Hernan A" sort="Burbano, Hernan A" uniqKey="Burbano H" first="Hernán A" last="Burbano">Hernán A. Burbano</name><affiliation><nlm:affiliation>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="P Bo, Svante" sort="P Bo, Svante" uniqKey="P Bo S" first="Svante" last="P Bo">Svante P Bo</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Meyer, Matthias" sort="Meyer, Matthias" uniqKey="Meyer M" first="Matthias" last="Meyer">Matthias Meyer</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany. viviane_slon@eva.mpg.de mmeyer@eva.mpg.de.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28450384</idno><idno type="pmid">28450384</idno><idno type="doi">10.1126/science.aam9695</idno><idno type="wicri:Area/PubMed/Corpus">000D00</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000D00</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Neandertal and Denisovan DNA from Pleistocene sediments.</title><author><name sortKey="Slon, Viviane" sort="Slon, Viviane" uniqKey="Slon V" first="Viviane" last="Slon">Viviane Slon</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany. viviane_slon@eva.mpg.de mmeyer@eva.mpg.de.</nlm:affiliation></affiliation></author><author><name sortKey="Hopfe, Charlotte" sort="Hopfe, Charlotte" uniqKey="Hopfe C" first="Charlotte" last="Hopfe">Charlotte Hopfe</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Wei, Clemens L" sort="Wei, Clemens L" uniqKey="Wei C" first="Clemens L" last="Wei">Clemens L. Wei</name><affiliation><nlm:affiliation>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Mafessoni, Fabrizio" sort="Mafessoni, Fabrizio" uniqKey="Mafessoni F" first="Fabrizio" last="Mafessoni">Fabrizio Mafessoni</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="De La Rasilla, Marco" sort="De La Rasilla, Marco" uniqKey="De La Rasilla M" first="Marco" last="De La Rasilla">Marco De La Rasilla</name><affiliation><nlm:affiliation>Área de Prehistoria, Department of History, Universidad de Oviedo, Calle Teniente Alfonso Martínez s/n, 33011 Oviedo, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Lalueza Fox, Carles" sort="Lalueza Fox, Carles" uniqKey="Lalueza Fox C" first="Carles" last="Lalueza-Fox">Carles Lalueza-Fox</name><affiliation><nlm:affiliation>Institute of Evolutionary Biology, Universitat Pompeu Fabra-Consejo Superior de Investigaciones Científicas (UPF-CSIC), 08003 Barcelona, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Rosas, Antonio" sort="Rosas, Antonio" uniqKey="Rosas A" first="Antonio" last="Rosas">Antonio Rosas</name><affiliation><nlm:affiliation>Departamento de Paleobiología, Museo Nacional de Ciencias Naturales, CSIC, 28006 Madrid, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Soressi, Marie" sort="Soressi, Marie" uniqKey="Soressi M" first="Marie" last="Soressi">Marie Soressi</name><affiliation><nlm:affiliation>Faculty of Archaeology, Leiden University, 2333CC Leiden, Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Knul, Monika V" sort="Knul, Monika V" uniqKey="Knul M" first="Monika V" last="Knul">Monika V. Knul</name><affiliation><nlm:affiliation>Faculty of Science and Technology, Bournemouth University, Poole, Dorset, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Miller, Rebecca" sort="Miller, Rebecca" uniqKey="Miller R" first="Rebecca" last="Miller">Rebecca Miller</name><affiliation><nlm:affiliation>Service de Préhistoire, Université de Liège, 4000 Liège, Belgium.</nlm:affiliation></affiliation></author><author><name sortKey="Stewart, John R" sort="Stewart, John R" uniqKey="Stewart J" first="John R" last="Stewart">John R. Stewart</name><affiliation><nlm:affiliation>Faculty of Science and Technology, Bournemouth University, Poole, Dorset, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Derevianko, Anatoly P" sort="Derevianko, Anatoly P" uniqKey="Derevianko A" first="Anatoly P" last="Derevianko">Anatoly P. Derevianko</name><affiliation><nlm:affiliation>Institute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk, RU-630090, Russia.</nlm:affiliation></affiliation></author><author><name sortKey="Jacobs, Zenobia" sort="Jacobs, Zenobia" uniqKey="Jacobs Z" first="Zenobia" last="Jacobs">Zenobia Jacobs</name><affiliation><nlm:affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Li, Bo" sort="Li, Bo" uniqKey="Li B" first="Bo" last="Li">Bo Li</name><affiliation><nlm:affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Roberts, Richard G" sort="Roberts, Richard G" uniqKey="Roberts R" first="Richard G" last="Roberts">Richard G. Roberts</name><affiliation><nlm:affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Shunkov, Michael V" sort="Shunkov, Michael V" uniqKey="Shunkov M" first="Michael V" last="Shunkov">Michael V. Shunkov</name><affiliation><nlm:affiliation>Institute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk, RU-630090, Russia.</nlm:affiliation></affiliation></author><author><name sortKey="De Lumley, Henry" sort="De Lumley, Henry" uniqKey="De Lumley H" first="Henry" last="De Lumley">Henry De Lumley</name><affiliation><nlm:affiliation>Centre Européen de Recherches Préhistoriques de Tautavel, 66720 Tautavel, France.</nlm:affiliation></affiliation></author><author><name sortKey="Perrenoud, Christian" sort="Perrenoud, Christian" uniqKey="Perrenoud C" first="Christian" last="Perrenoud">Christian Perrenoud</name><affiliation><nlm:affiliation>Centre Européen de Recherches Préhistoriques de Tautavel, 66720 Tautavel, France.</nlm:affiliation></affiliation></author><author><name sortKey="Gusi, Ivan" sort="Gusi, Ivan" uniqKey="Gusi I" first="Ivan" last="Guši">Ivan Guši</name><affiliation><nlm:affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Ku An, Zeljko" sort="Ku An, Zeljko" uniqKey="Ku An Z" first="Željko" last="Ku An">Željko Ku An</name><affiliation><nlm:affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Rudan, Pavao" sort="Rudan, Pavao" uniqKey="Rudan P" first="Pavao" last="Rudan">Pavao Rudan</name><affiliation><nlm:affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Aximu Petri, Ayinuer" sort="Aximu Petri, Ayinuer" uniqKey="Aximu Petri A" first="Ayinuer" last="Aximu-Petri">Ayinuer Aximu-Petri</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Essel, Elena" sort="Essel, Elena" uniqKey="Essel E" first="Elena" last="Essel">Elena Essel</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Nagel, Sarah" sort="Nagel, Sarah" uniqKey="Nagel S" first="Sarah" last="Nagel">Sarah Nagel</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Nickel, Birgit" sort="Nickel, Birgit" uniqKey="Nickel B" first="Birgit" last="Nickel">Birgit Nickel</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Schmidt, Anna" sort="Schmidt, Anna" uniqKey="Schmidt A" first="Anna" last="Schmidt">Anna Schmidt</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Prufer, Kay" sort="Prufer, Kay" uniqKey="Prufer K" first="Kay" last="Prüfer">Kay Prüfer</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Kelso, Janet" sort="Kelso, Janet" uniqKey="Kelso J" first="Janet" last="Kelso">Janet Kelso</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Burbano, Hernan A" sort="Burbano, Hernan A" uniqKey="Burbano H" first="Hernán A" last="Burbano">Hernán A. Burbano</name><affiliation><nlm:affiliation>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="P Bo, Svante" sort="P Bo, Svante" uniqKey="P Bo S" first="Svante" last="P Bo">Svante P Bo</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Meyer, Matthias" sort="Meyer, Matthias" uniqKey="Meyer M" first="Matthias" last="Meyer">Matthias Meyer</name><affiliation><nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany. viviane_slon@eva.mpg.de mmeyer@eva.mpg.de.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Science (New York, N.Y.)</title><idno type="eISSN">1095-9203</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">28450384</PMID><DateCreated><Year>2017</Year><Month>04</Month><Day>28</Day></DateCreated><DateRevised><Year>2017</Year><Month>10</Month><Day>12</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1095-9203</ISSN><JournalIssue CitedMedium="Internet"><Volume>356</Volume><Issue>6338</Issue><PubDate><Year>2017</Year><Month>05</Month><Day>12</Day></PubDate></JournalIssue><Title>Science (New York, N.Y.)</Title><ISOAbbreviation>Science</ISOAbbreviation></Journal><ArticleTitle>Neandertal and Denisovan DNA from Pleistocene sediments.</ArticleTitle><Pagination><MedlinePgn>605-608</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1126/science.aam9695</ELocationID><Abstract><AbstractText>Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.</AbstractText><CopyrightInformation>Copyright © 2017, American Association for the Advancement of Science.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Slon</LastName><ForeName>Viviane</ForeName><Initials>V</Initials><Identifier Source="ORCID">0000-0001-6485-7159</Identifier><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany. viviane_slon@eva.mpg.de mmeyer@eva.mpg.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hopfe</LastName><ForeName>Charlotte</ForeName><Initials>C</Initials><Identifier Source="ORCID">0000-0003-0662-081X</Identifier><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Weiß</LastName><ForeName>Clemens L</ForeName><Initials>CL</Initials><AffiliationInfo><Affiliation>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mafessoni</LastName><ForeName>Fabrizio</ForeName><Initials>F</Initials><Identifier Source="ORCID">0000-0003-4319-2076</Identifier><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de la Rasilla</LastName><ForeName>Marco</ForeName><Initials>M</Initials><Identifier Source="ORCID">0000-0002-5505-0625</Identifier><AffiliationInfo><Affiliation>Área de Prehistoria, Department of History, Universidad de Oviedo, Calle Teniente Alfonso Martínez s/n, 33011 Oviedo, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lalueza-Fox</LastName><ForeName>Carles</ForeName><Initials>C</Initials><Identifier Source="ORCID">0000-0002-1730-5914</Identifier><AffiliationInfo><Affiliation>Institute of Evolutionary Biology, Universitat Pompeu Fabra-Consejo Superior de Investigaciones Científicas (UPF-CSIC), 08003 Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rosas</LastName><ForeName>Antonio</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Departamento de Paleobiología, Museo Nacional de Ciencias Naturales, CSIC, 28006 Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Soressi</LastName><ForeName>Marie</ForeName><Initials>M</Initials><Identifier Source="ORCID">0000-0003-1733-7745</Identifier><AffiliationInfo><Affiliation>Faculty of Archaeology, Leiden University, 2333CC Leiden, Netherlands.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Knul</LastName><ForeName>Monika V</ForeName><Initials>MV</Initials><Identifier Source="ORCID">0000-0002-0650-0992</Identifier><AffiliationInfo><Affiliation>Faculty of Science and Technology, Bournemouth University, Poole, Dorset, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Miller</LastName><ForeName>Rebecca</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Service de Préhistoire, Université de Liège, 4000 Liège, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stewart</LastName><ForeName>John R</ForeName><Initials>JR</Initials><AffiliationInfo><Affiliation>Faculty of Science and Technology, Bournemouth University, Poole, Dorset, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Derevianko</LastName><ForeName>Anatoly P</ForeName><Initials>AP</Initials><AffiliationInfo><Affiliation>Institute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk, RU-630090, Russia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Altai State University, Barnaul, RU-656049, Russia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jacobs</LastName><ForeName>Zenobia</ForeName><Initials>Z</Initials><Identifier Source="ORCID">0000-0001-5424-5837</Identifier><AffiliationInfo><Affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Australian Research Council (ARC) Centre of Excellence for Australian Biodiversity and Heritage, University of Wollongong, Wollongong, New South Wales 2522, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Bo</ForeName><Initials>B</Initials><Identifier Source="ORCID">0000-0003-4186-4828</Identifier><AffiliationInfo><Affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Roberts</LastName><ForeName>Richard G</ForeName><Initials>RG</Initials><Identifier Source="ORCID">0000-0002-0128-4119</Identifier><AffiliationInfo><Affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Australian Research Council (ARC) Centre of Excellence for Australian Biodiversity and Heritage, University of Wollongong, Wollongong, New South Wales 2522, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shunkov</LastName><ForeName>Michael V</ForeName><Initials>MV</Initials><AffiliationInfo><Affiliation>Institute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk, RU-630090, Russia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Novosibirsk National Research State University, Novosibirsk, RU-630090, Russia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Lumley</LastName><ForeName>Henry</ForeName><Initials>H</Initials><Identifier Source="ORCID">0000-0001-5442-1669</Identifier><AffiliationInfo><Affiliation>Centre Européen de Recherches Préhistoriques de Tautavel, 66720 Tautavel, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institut de Paléontologie Humaine, 75013 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Perrenoud</LastName><ForeName>Christian</ForeName><Initials>C</Initials><Identifier Source="ORCID">0000-0001-9704-1172</Identifier><AffiliationInfo><Affiliation>Centre Européen de Recherches Préhistoriques de Tautavel, 66720 Tautavel, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Muséum national d'Histoire naturelle, Département Homme et Environnement, UMR 7194 HNHP, 75013 Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gušić</LastName><ForeName>Ivan</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kućan</LastName><ForeName>Željko</ForeName><Initials>Ž</Initials><AffiliationInfo><Affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rudan</LastName><ForeName>Pavao</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Anthropology Center of the Croatian Academy of Sciences and Arts, 10000 Zagreb, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Aximu-Petri</LastName><ForeName>Ayinuer</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Essel</LastName><ForeName>Elena</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nagel</LastName><ForeName>Sarah</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nickel</LastName><ForeName>Birgit</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schmidt</LastName><ForeName>Anna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Prüfer</LastName><ForeName>Kay</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kelso</LastName><ForeName>Janet</ForeName><Initials>J</Initials><Identifier Source="ORCID">0000-0002-3618-322X</Identifier><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Burbano</LastName><ForeName>Hernán A</ForeName><Initials>HA</Initials><Identifier Source="ORCID">0000-0003-3433-719X</Identifier><AffiliationInfo><Affiliation>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pääbo</LastName><ForeName>Svante</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Meyer</LastName><ForeName>Matthias</ForeName><Initials>M</Initials><Identifier Source="ORCID">0000-0002-4760-558X</Identifier><AffiliationInfo><Affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany. viviane_slon@eva.mpg.de mmeyer@eva.mpg.de.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><DataBankList CompleteYN="Y"><DataBank><DataBankName>Dryad</DataBankName><AccessionNumberList><AccessionNumber>m2dk7</AccessionNumber></AccessionNumberList></DataBank></DataBankList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>04</Month><Day>27</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Science</MedlineTA><NlmUniqueID>0404511</NlmUniqueID><ISSNLinking>0036-8075</ISSNLinking></MedlineJournalInfo></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>02</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>04</Month><Day>07</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>4</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>4</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>4</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28450384</ArticleId><ArticleId IdType="pii">science.aam9695</ArticleId><ArticleId IdType="doi">10.1126/science.aam9695</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000D00 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000D00 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:28450384
|texte= Neandertal and Denisovan DNA from Pleistocene sediments.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:28450384" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |