A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
Identifieur interne : 001F87 ( Pmc/Curation ); précédent : 001F86; suivant : 001F88A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
Auteurs : Alisa K. Manning [États-Unis] ; Marie-France Hivert [États-Unis, Canada] ; Robert A. Scott [Royaume-Uni] ; Jonna L. Grimsby [États-Unis] ; Nabila Bouatia-Naji [France] ; Han Chen [États-Unis] ; Denis Rybin [États-Unis] ; Ching-Ti Liu [États-Unis] ; Lawrence F. Bielak [États-Unis] ; Inga Prokopenko [Royaume-Uni] ; Najaf Amin [Pays-Bas] ; Daniel Barnes [Royaume-Uni] ; Gemma Cadby [Canada] ; Jouke-Jan Hottenga [Pays-Bas] ; Erik Ingelsson [Suède] ; Anne U. Jackson [États-Unis] ; Toby Johnson [Royaume-Uni] ; Stavroula Kanoni [Royaume-Uni] ; Claes Ladenvall [Suède] ; Vasiliki Lagou [Royaume-Uni] ; Jari Lahti [Finlande] ; Cecile Lecoeur [France] ; Yongmei Liu [États-Unis] ; Maria Teresa Martinez-Larrad [Espagne] ; May E. Montasser [États-Unis] ; Pau Navarro [Royaume-Uni] ; John R. B. Perry [Royaume-Uni] ; Laura J. Rasmussen-Torvik [États-Unis] ; Perttu Salo [Finlande] ; Naveed Sattar [Royaume-Uni] ; Dmitry Shungin [Suède] ; Rona J. Strawbridge [Suède] ; Toshiko Tanaka [États-Unis] ; Cornelia M. Van Duijn [Pays-Bas] ; Ping An [États-Unis] ; Mariza De Andrade [États-Unis] ; Jeanette S. Andrews [États-Unis] ; Thor Aspelund [Islande] ; Mustafa Atalay [Finlande] ; Yurii Aulchenko [Pays-Bas] ; Beverley Balkau [France] ; Stefania Bandinelli [Italie] ; Jacques S. Beckmann [Suisse] ; John P. Beilby [Australie] ; Claire Bellis [États-Unis] ; Richard N. Bergman [États-Unis] ; John Blangero [États-Unis] ; Mladen Boban [Croatie] ; Michael Boehnke [États-Unis] ; Eric Boerwinkle [États-Unis] ; Lori L. Bonnycastle [États-Unis] ; Dorret I. Boomsma [Pays-Bas] ; Ingrid B. Borecki [États-Unis] ; Yvonne Böttcher [Allemagne] ; Claude Bouchard [États-Unis] ; Eric Brunner [Royaume-Uni] ; Danijela Budimir [Croatie] ; Harry Campbell [Royaume-Uni] ; Olga Carlson [États-Unis] ; Peter S. Chines [États-Unis] ; Robert Clarke [Royaume-Uni] ; Francis S. Collins [États-Unis] ; Arturo Corbat N-Anchuelo [Espagne] ; David Couper [États-Unis] ; Ulf De Faire [Suède] ; George V. Dedoussis [Grèce] ; Panos Deloukas [Royaume-Uni] ; Maria Dimitriou [Grèce] ; Josephine M. Egan [États-Unis] ; Gudny Eiriksdottir [Islande] ; Michael R. Erdos [États-Unis] ; Johan G. Eriksson [Finlande] ; Elodie Eury [France] ; Luigi Ferrucci [États-Unis] ; Ian Ford [Royaume-Uni] ; Nita G. Forouhi [Royaume-Uni] ; Caroline S. Fox [États-Unis] ; Maria Grazia Franzosi [Italie] ; Paul W. Franks [Suède, États-Unis, France] ; Timothy M. Frayling [Royaume-Uni] ; Philippe Froguel [France, Royaume-Uni] ; Pilar Galan [France] ; Eco De Geus [Pays-Bas] ; Bruna Gigante [Suède] ; Nicole L. Glazer [États-Unis] ; Anuj Goel [Royaume-Uni] ; Leif Groop [Suède] ; Vilmundur Gudnason [Islande] ; Göran Hallmans [Suède] ; Anders Hamsten [Suède] ; Ola Hansson [Suède] ; Tamara B. Harris [États-Unis] ; Caroline Hayward [Royaume-Uni] ; Simon Heath [France] ; Serge Hercberg [France] ; Andrew A. Hicks [Allemagne] ; Aroon Hingorani [Royaume-Uni] ; Albert Hofman [Pays-Bas] ; Jennie Hui [Australie] ; Joseph Hung [Australie] ; Marjo Riitta Jarvelin [Royaume-Uni, Finlande] ; Min A. Jhun [États-Unis] ; Paul C. D. Johnson [Royaume-Uni] ; J Wouter Jukema [Pays-Bas] ; Antti Jula [Finlande] ; W. H. Kao [États-Unis] ; Jaakko Kaprio [Finlande] ; Sharon L. R. Kardia [États-Unis] ; Sirkka Keinanen-Kiukaanniemi [Finlande] ; Mika Kivimaki [Royaume-Uni] ; Ivana Kolcic [Croatie] ; Peter Kovacs [Allemagne] ; Meena Kumari [Royaume-Uni] ; Johanna Kuusisto [Finlande] ; Kirsten Ohm Kyvik ; Markku Laakso [Finlande] ; Timo Lakka [Finlande] ; Lars Lannfelt [Suède] ; G Mark Lathrop [France] ; Lenore J. Launer [États-Unis] ; Karin Leander [Suède] ; Guo Li [États-Unis] ; Lars Lind [Suède] ; Jaana Lindstrom [Finlande] ; Stéphane Lobbens [France] ; Ruth J. F. Loos [Royaume-Uni] ; Jian N Luan [Royaume-Uni] ; Valeriya Lyssenko [Suède] ; Reedik M Gi [Royaume-Uni, Estonie] ; Patrik K. E. Magnusson [Suède] ; Michael Marmot [Royaume-Uni] ; Pierre Meneton [France] ; Karen L. Mohlke [États-Unis] ; Vincent Mooser [États-Unis] ; Mario A. Morken [États-Unis] ; Iva Miljkovic [États-Unis] ; Narisu Narisu [États-Unis] ; Jeff O Onnell [États-Unis] ; Ken K. Ong [Royaume-Uni] ; Ben A. Oostra [Pays-Bas] ; Lyle J. Palmer [Canada] ; Aarno Palotie [États-Unis, Royaume-Uni, Finlande] ; James S. Pankow [États-Unis] ; John F. Peden [Royaume-Uni] ; Nancy L. Pedersen [Suède] ; Marina Pehlic [Croatie] ; Leena Peltonen [Royaume-Uni, Finlande] ; Brenda Penninx [Pays-Bas] ; Marijana Pericic [Croatie] ; Markus Perola [Finlande] ; Louis Perusse [Canada] ; Patricia A. Peyser [États-Unis] ; Ozren Polasek [Croatie] ; Peter P. Pramstaller [Allemagne] ; Michael A. Province [États-Unis] ; Katri R Ikkönen [Finlande] ; Rainer Rauramaa [Finlande] ; Emil Rehnberg [Suède] ; Ken Rice [États-Unis] ; Jerome I. Rotter ; Igor Rudan [Royaume-Uni, Croatie] ; Aimo Ruokonen [Finlande] ; Timo Saaristo [Finlande] ; Maria Sabater-Lleal [Suède] ; Veikko Salomaa [Finlande] ; David B. Savage [Royaume-Uni] ; Richa Saxena [États-Unis] ; Peter Schwarz [Allemagne] ; Udo Seedorf [Allemagne] ; Bengt Sennblad [Suède] ; Manuel Serrano-Rios [Espagne] ; Alan R. Shuldiner [États-Unis] ; Eric J. G. Sijbrands [Pays-Bas] ; David S. Siscovick [États-Unis] ; Johannes H. Smit [Pays-Bas] ; Kerrin S. Small [Royaume-Uni] ; Nicholas L. Smith [États-Unis] ; Albert Vernon Smith [Islande] ; Alena Stan Ková [Finlande] ; Kathleen Stirrups [Royaume-Uni] ; Michael Stumvoll [Allemagne] ; Yan V. Sun [États-Unis] ; Amy J. Swift [États-Unis] ; Anke Tönjes [Allemagne] ; Jaakko Tuomilehto [Finlande, Espagne, Autriche] ; Stella Trompet [Pays-Bas] ; Andre G. Uitterlinden [Pays-Bas] ; Matti Uusitupa [Finlande] ; Max Vikström [Suède] ; Veronique Vitart [Royaume-Uni] ; Marie-Claude Vohl [Canada] ; Benjamin F. Voight [États-Unis] ; Peter Vollenweider [Suisse] ; Gerard Waeber [Suisse] ; Dawn M. Waterworth [États-Unis] ; Hugh Watkins [Royaume-Uni] ; Eleanor Wheeler [Royaume-Uni] ; Elisabeth Widen [Finlande] ; Sarah H. Wild [Royaume-Uni] ; Sara M. Willems [Pays-Bas] ; Gonneke Willemsen [Pays-Bas] ; James F. Wilson [Royaume-Uni] ; Jacqueline C. M. Witteman [Pays-Bas] ; Alan F. Wright [Royaume-Uni] ; Hanieh Yaghootkar [Royaume-Uni] ; Diana Zelenika [France] ; Tatijana Zemunik [Croatie] ; Lina Zgaga [Royaume-Uni, Croatie] ; Nicholas J. Wareham [Royaume-Uni] ; Mark I. Mccarthy [Royaume-Uni] ; Ines Barroso [Royaume-Uni] ; Richard M. Watanabe [États-Unis] ; Jose C. Florez [États-Unis] ; Josée Dupuis [États-Unis] ; James B. Meigs [États-Unis] ; Claudia Langenberg [Royaume-Uni]Source :
- Nature genetics [ 1061-4036 ] ; 2012.
Abstract
Recent genome-wide association studies have described many loci implicated in type 2 diabetes (T2D) pathophysiology and beta-cell dysfunction, but contributed little to our understanding of the genetic basis of insulin resistance. We hypothesized that genes implicated in insulin resistance pathways may be uncovered by accounting for differences in body mass index (BMI) and potential interaction between BMI and genetic variants. We applied a novel joint meta-analytical approach to test associations with fasting insulin (FI) and glucose (FG) on a genome-wide scale. We present six previously unknown FI loci at
Url:
DOI: 10.1038/ng.2274
PubMed: 22581228
PubMed Central: 3613127
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Cornelia M. Van Duijn<affiliation><nlm:aff id="A39">Centre for medical systems biology, Netherlands Genomics Initiative, The Hague</nlm:aff>
<wicri:noCountry code="subfield">The Hague</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A40">Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam</wicri:regionArea>
</affiliation>
<affiliation><nlm:aff id="A130">Medical Genetics Institute, Cedars-Sinai Medical Center</nlm:aff>
<wicri:noCountry code="subfield">Cedars-Sinai Medical Center</wicri:noCountry>
</affiliation>
Le document en format XML
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<author><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U." last="Jackson">Anne U. Jackson</name>
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<author><name sortKey="Johnson, Toby" sort="Johnson, Toby" uniqKey="Johnson T" first="Toby" last="Johnson">Toby Johnson</name>
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<author><name sortKey="Ladenvall, Claes" sort="Ladenvall, Claes" uniqKey="Ladenvall C" first="Claes" last="Ladenvall">Claes Ladenvall</name>
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<author><name sortKey="Lahti, Jari" sort="Lahti, Jari" uniqKey="Lahti J" first="Jari" last="Lahti">Jari Lahti</name>
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<wicri:regionArea>Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea>
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<author><name sortKey="Lecoeur, Cecile" sort="Lecoeur, Cecile" uniqKey="Lecoeur C" first="Cecile" last="Lecoeur">Cecile Lecoeur</name>
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<affiliation wicri:level="1"><nlm:aff id="A10">Lille Nord de France University, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Lille Nord de France University, Lille</wicri:regionArea>
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<author><name sortKey="Liu, Yongmei" sort="Liu, Yongmei" uniqKey="Liu Y" first="Yongmei" last="Liu">Yongmei Liu</name>
<affiliation wicri:level="1"><nlm:aff id="A26">Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina</wicri:regionArea>
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<author><name sortKey="Martinez Larrad, Maria Teresa" sort="Martinez Larrad, Maria Teresa" uniqKey="Martinez Larrad M" first="Maria Teresa" last="Martinez-Larrad">Maria Teresa Martinez-Larrad</name>
<affiliation wicri:level="1"><nlm:aff id="A27">Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Montasser, May E" sort="Montasser, May E" uniqKey="Montasser M" first="May E." last="Montasser">May E. Montasser</name>
<affiliation wicri:level="1"><nlm:aff id="A28">Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Navarro, Pau" sort="Navarro, Pau" uniqKey="Navarro P" first="Pau" last="Navarro">Pau Navarro</name>
<affiliation wicri:level="1"><nlm:aff id="A29">MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Perry, John R B" sort="Perry, John R B" uniqKey="Perry J" first="John R. B." last="Perry">John R. B. Perry</name>
<affiliation wicri:level="1"><nlm:aff id="A14">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A30">Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A31">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rasmussen Torvik, Laura J" sort="Rasmussen Torvik, Laura J" uniqKey="Rasmussen Torvik L" first="Laura J." last="Rasmussen-Torvik">Laura J. Rasmussen-Torvik</name>
<affiliation wicri:level="1"><nlm:aff id="A32">Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Salo, Perttu" sort="Salo, Perttu" uniqKey="Salo P" first="Perttu" last="Salo">Perttu Salo</name>
<affiliation wicri:level="1"><nlm:aff id="A33">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sattar, Naveed" sort="Sattar, Naveed" uniqKey="Sattar N" first="Naveed" last="Sattar">Naveed Sattar</name>
<affiliation wicri:level="1"><nlm:aff id="A34">Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Cardiovascular and Medical Sciences, University of Glasgow</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shungin, Dmitry" sort="Shungin, Dmitry" uniqKey="Shungin D" first="Dmitry" last="Shungin">Dmitry Shungin</name>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A24">Lund University Diabetes Centre, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Lund University Diabetes Centre, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A35">Department of Public Health & Clinical Medicine, Genetic Epidemiology & Clinical Research Group, Umeå University Hospital, Umeå, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Public Health & Clinical Medicine, Genetic Epidemiology & Clinical Research Group, Umeå University Hospital, Umeå</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A36">Department of Odontology, Umeå University, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Odontology, Umeå University</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Strawbridge, Rona J" sort="Strawbridge, Rona J" uniqKey="Strawbridge R" first="Rona J." last="Strawbridge">Rona J. Strawbridge</name>
<affiliation wicri:level="1"><nlm:aff id="A37">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name>
<affiliation wicri:level="1"><nlm:aff id="A38">Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M." last="Van Duijn">Cornelia M. Van Duijn</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
<affiliation><nlm:aff id="A39">Centre for medical systems biology, Netherlands Genomics Initiative, The Hague</nlm:aff>
<wicri:noCountry code="subfield">The Hague</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A40">Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="An, Ping" sort="An, Ping" uniqKey="An P" first="Ping" last="An">Ping An</name>
<affiliation wicri:level="1"><nlm:aff id="A41">Department of Genetics Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Genetics Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Andrade, Mariza" sort="De Andrade, Mariza" uniqKey="De Andrade M" first="Mariza" last="De Andrade">Mariza De Andrade</name>
<affiliation wicri:level="1"><nlm:aff id="A42">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Andrews, Jeanette S" sort="Andrews, Jeanette S" uniqKey="Andrews J" first="Jeanette S." last="Andrews">Jeanette S. Andrews</name>
<affiliation wicri:level="1"><nlm:aff id="A43">Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Aspelund, Thor" sort="Aspelund, Thor" uniqKey="Aspelund T" first="Thor" last="Aspelund">Thor Aspelund</name>
<affiliation wicri:level="1"><nlm:aff id="A44">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A45">University of Iceland, Reykjavik, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>University of Iceland, Reykjavik</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Atalay, Mustafa" sort="Atalay, Mustafa" uniqKey="Atalay M" first="Mustafa" last="Atalay">Mustafa Atalay</name>
<affiliation wicri:level="1"><nlm:aff id="A46">Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Kuopio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Aulchenko, Yurii" sort="Aulchenko, Yurii" uniqKey="Aulchenko Y" first="Yurii" last="Aulchenko">Yurii Aulchenko</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Balkau, Beverley" sort="Balkau, Beverley" uniqKey="Balkau B" first="Beverley" last="Balkau">Beverley Balkau</name>
<affiliation wicri:level="1"><nlm:aff id="A47">Inserm, CESP Centre for research in Epidemiology and Population Health, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Inserm, CESP Centre for research in Epidemiology and Population Health, Villejuif</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A48">University Paris Sud 11, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>University Paris Sud 11, Villejuif</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bandinelli, Stefania" sort="Bandinelli, Stefania" uniqKey="Bandinelli S" first="Stefania" last="Bandinelli">Stefania Bandinelli</name>
<affiliation wicri:level="1"><nlm:aff id="A49">Geriatric Unit, Azienda Sanitaria di Firenze, Florence, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Geriatric Unit, Azienda Sanitaria di Firenze, Florence</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Beckmann, Jacques S" sort="Beckmann, Jacques S" uniqKey="Beckmann J" first="Jacques S." last="Beckmann">Jacques S. Beckmann</name>
<affiliation wicri:level="1"><nlm:aff id="A50">Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A51">Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois, Lausanne</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Beilby, John P" sort="Beilby, John P" uniqKey="Beilby J" first="John P." last="Beilby">John P. Beilby</name>
<affiliation wicri:level="1"><nlm:aff id="A52">PathWest Laboratory Medicine of WA, J Block, QEII Medical Centre, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>PathWest Laboratory Medicine of WA, J Block, QEII Medical Centre, Nedlands</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A53">School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A54">Busselton Population Medical Research Foundation, B Block, QEII Medical Centre, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Busselton Population Medical Research Foundation, B Block, QEII Medical Centre, Nedlands</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bellis, Claire" sort="Bellis, Claire" uniqKey="Bellis C" first="Claire" last="Bellis">Claire Bellis</name>
<affiliation wicri:level="1"><nlm:aff id="A55">Texas Biomedical Research Institute, San Antonio, Texas, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Texas Biomedical Research Institute, San Antonio, Texas</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bergman, Richard N" sort="Bergman, Richard N" uniqKey="Bergman R" first="Richard N." last="Bergman">Richard N. Bergman</name>
<affiliation wicri:level="1"><nlm:aff id="A56">Department of Physiology & Biophysics, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Physiology & Biophysics, Keck School of Medicine of the University of Southern California, Los Angeles, California</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Blangero, John" sort="Blangero, John" uniqKey="Blangero J" first="John" last="Blangero">John Blangero</name>
<affiliation wicri:level="1"><nlm:aff id="A55">Texas Biomedical Research Institute, San Antonio, Texas, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Texas Biomedical Research Institute, San Antonio, Texas</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boban, Mladen" sort="Boban, Mladen" uniqKey="Boban M" first="Mladen" last="Boban">Mladen Boban</name>
<affiliation wicri:level="1"><nlm:aff id="A57">Department of Pharmacology, Faculty of Medicine, University of Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Department of Pharmacology, Faculty of Medicine, University of Split</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name>
<affiliation wicri:level="1"><nlm:aff id="A20">Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name>
<affiliation wicri:level="1"><nlm:aff id="A58">Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bonnycastle, Lori L" sort="Bonnycastle, Lori L" uniqKey="Bonnycastle L" first="Lori L." last="Bonnycastle">Lori L. Bonnycastle</name>
<affiliation wicri:level="1"><nlm:aff id="A59">Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I." last="Boomsma">Dorret I. Boomsma</name>
<affiliation wicri:level="1"><nlm:aff id="A18">Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Borecki, Ingrid B" sort="Borecki, Ingrid B" uniqKey="Borecki I" first="Ingrid B." last="Borecki">Ingrid B. Borecki</name>
<affiliation wicri:level="1"><nlm:aff id="A41">Department of Genetics Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Genetics Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bottcher, Yvonne" sort="Bottcher, Yvonne" uniqKey="Bottcher Y" first="Yvonne" last="Böttcher">Yvonne Böttcher</name>
<affiliation wicri:level="1"><nlm:aff id="A60">IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>IFB Adiposity Diseases, University of Leipzig, Leipzig</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bouchard, Claude" sort="Bouchard, Claude" uniqKey="Bouchard C" first="Claude" last="Bouchard">Claude Bouchard</name>
<affiliation wicri:level="1"><nlm:aff id="A61">Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Pennington Biomedical Research Center, Baton Rouge, Louisiana</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brunner, Eric" sort="Brunner, Eric" uniqKey="Brunner E" first="Eric" last="Brunner">Eric Brunner</name>
<affiliation wicri:level="1"><nlm:aff id="A62">University College London, Department of Epidemiology & Public Health, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>University College London, Department of Epidemiology & Public Health, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Budimir, Danijela" sort="Budimir, Danijela" uniqKey="Budimir D" first="Danijela" last="Budimir">Danijela Budimir</name>
<affiliation wicri:level="1"><nlm:aff id="A57">Department of Pharmacology, Faculty of Medicine, University of Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Department of Pharmacology, Faculty of Medicine, University of Split</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name>
<affiliation wicri:level="1"><nlm:aff id="A63">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Carlson, Olga" sort="Carlson, Olga" uniqKey="Carlson O" first="Olga" last="Carlson">Olga Carlson</name>
<affiliation wicri:level="1"><nlm:aff id="A64">Laboratory of Clinical Investigation, National Institute of Aging, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Laboratory of Clinical Investigation, National Institute of Aging, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chines, Peter S" sort="Chines, Peter S" uniqKey="Chines P" first="Peter S." last="Chines">Peter S. Chines</name>
<affiliation wicri:level="1"><nlm:aff id="A59">Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Clarke, Robert" sort="Clarke, Robert" uniqKey="Clarke R" first="Robert" last="Clarke">Robert Clarke</name>
<affiliation wicri:level="1"><nlm:aff id="A65">Clinical Trial Service Unit, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Clinical Trial Service Unit, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Collins, Francis S" sort="Collins, Francis S" uniqKey="Collins F" first="Francis S." last="Collins">Francis S. Collins</name>
<affiliation wicri:level="1"><nlm:aff id="A66">Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Corbat N Anchuelo, Arturo" sort="Corbat N Anchuelo, Arturo" uniqKey="Corbat N Anchuelo A" first="Arturo" last="Corbat N-Anchuelo">Arturo Corbat N-Anchuelo</name>
<affiliation wicri:level="1"><nlm:aff id="A27">Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Couper, David" sort="Couper, David" uniqKey="Couper D" first="David" last="Couper">David Couper</name>
<affiliation wicri:level="1"><nlm:aff id="A67">Department of Biostatistics, University of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biostatistics, University of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Faire, Ulf" sort="De Faire, Ulf" uniqKey="De Faire U" first="Ulf" last="De Faire">Ulf De Faire</name>
<affiliation wicri:level="1"><nlm:aff id="A68">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dedoussis, George V" sort="Dedoussis, George V" uniqKey="Dedoussis G" first="George V" last="Dedoussis">George V. Dedoussis</name>
<affiliation wicri:level="1"><nlm:aff id="A69">Department of Nutrition - Dietetics, Harokopio University, Athens, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Nutrition - Dietetics, Harokopio University, Athens</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name>
<affiliation wicri:level="1"><nlm:aff id="A22">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dimitriou, Maria" sort="Dimitriou, Maria" uniqKey="Dimitriou M" first="Maria" last="Dimitriou">Maria Dimitriou</name>
<affiliation wicri:level="1"><nlm:aff id="A69">Department of Nutrition - Dietetics, Harokopio University, Athens, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Nutrition - Dietetics, Harokopio University, Athens</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Egan, Josephine M" sort="Egan, Josephine M" uniqKey="Egan J" first="Josephine M" last="Egan">Josephine M. Egan</name>
<affiliation wicri:level="1"><nlm:aff id="A64">Laboratory of Clinical Investigation, National Institute of Aging, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Laboratory of Clinical Investigation, National Institute of Aging, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eiriksdottir, Gudny" sort="Eiriksdottir, Gudny" uniqKey="Eiriksdottir G" first="Gudny" last="Eiriksdottir">Gudny Eiriksdottir</name>
<affiliation wicri:level="1"><nlm:aff id="A44">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Erdos, Michael R" sort="Erdos, Michael R" uniqKey="Erdos M" first="Michael R." last="Erdos">Michael R. Erdos</name>
<affiliation wicri:level="1"><nlm:aff id="A59">Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G." last="Eriksson">Johan G. Eriksson</name>
<affiliation wicri:level="1"><nlm:aff id="A70">Department of General Practice and Primary health Care, University of Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of General Practice and Primary health Care, University of Helsinki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A71">Helsinki University Central Hospital, Unit of General Practice, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Helsinki University Central Hospital, Unit of General Practice, Helsinki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A72">Folkhalsan Research Centre, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Folkhalsan Research Centre, Helsinki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A73">Vaasa Central Hospital, Vaasa, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Vaasa Central Hospital, Vaasa</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A74">National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eury, Elodie" sort="Eury, Elodie" uniqKey="Eury E" first="Elodie" last="Eury">Elodie Eury</name>
<affiliation wicri:level="1"><nlm:aff id="A9">Institut Pasteur de Lille, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A10">Lille Nord de France University, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Lille Nord de France University, Lille</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name>
<affiliation wicri:level="1"><nlm:aff id="A75">Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ford, Ian" sort="Ford, Ian" uniqKey="Ford I" first="Ian" last="Ford">Ian Ford</name>
<affiliation wicri:level="1"><nlm:aff id="A76">Robertson Centre for Biostatistics, University of Glasgow, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Robertson Centre for Biostatistics, University of Glasgow</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Forouhi, Nita G" sort="Forouhi, Nita G" uniqKey="Forouhi N" first="Nita G." last="Forouhi">Nita G. Forouhi</name>
<affiliation wicri:level="1"><nlm:aff id="A7">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fox, Caroline S" sort="Fox, Caroline S" uniqKey="Fox C" first="Caroline S" last="Fox">Caroline S. Fox</name>
<affiliation wicri:level="1"><nlm:aff id="A77">National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A78">Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Franzosi, Maria Grazia" sort="Franzosi, Maria Grazia" uniqKey="Franzosi M" first="Maria Grazia" last="Franzosi">Maria Grazia Franzosi</name>
<affiliation wicri:level="1"><nlm:aff id="A79">Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research, Milan, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research, Milan</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Franks, Paul W" sort="Franks, Paul W" uniqKey="Franks P" first="Paul W" last="Franks">Paul W. Franks</name>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A24">Lund University Diabetes Centre, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Lund University Diabetes Centre, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A35">Department of Public Health & Clinical Medicine, Genetic Epidemiology & Clinical Research Group, Umeå University Hospital, Umeå, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Public Health & Clinical Medicine, Genetic Epidemiology & Clinical Research Group, Umeå University Hospital, Umeå</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A80">Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A81">Institut National de la Recherche Agronomique, Université Paris, Bobigny Cedex, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National de la Recherche Agronomique, Université Paris, Bobigny Cedex</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Frayling, Timothy M" sort="Frayling, Timothy M" uniqKey="Frayling T" first="Timothy M" last="Frayling">Timothy M. Frayling</name>
<affiliation wicri:level="1"><nlm:aff id="A30">Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Froguel, Philippe" sort="Froguel, Philippe" uniqKey="Froguel P" first="Philippe" last="Froguel">Philippe Froguel</name>
<affiliation wicri:level="1"><nlm:aff id="A9">Institut Pasteur de Lille, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A10">Lille Nord de France University, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Lille Nord de France University, Lille</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A82">Genomic Medicine, Hammersmith Hospital, Imperial College London, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Genomic Medicine, Hammersmith Hospital, Imperial College London, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Galan, Pilar" sort="Galan, Pilar" uniqKey="Galan P" first="Pilar" last="Galan">Pilar Galan</name>
<affiliation wicri:level="1"><nlm:aff id="A83">Institut National de la Santé et de la Recherche Médicale, Université Paris, Bobigny Cedex, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National de la Santé et de la Recherche Médicale, Université Paris, Bobigny Cedex</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Geus, Eco" sort="De Geus, Eco" uniqKey="De Geus E" first="Eco" last="De Geus">Eco De Geus</name>
<affiliation wicri:level="1"><nlm:aff id="A18">Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gigante, Bruna" sort="Gigante, Bruna" uniqKey="Gigante B" first="Bruna" last="Gigante">Bruna Gigante</name>
<affiliation wicri:level="1"><nlm:aff id="A68">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Glazer, Nicole L" sort="Glazer, Nicole L" uniqKey="Glazer N" first="Nicole L." last="Glazer">Nicole L. Glazer</name>
<affiliation wicri:level="1"><nlm:aff id="A84">Department of Medicine, Section of Preventive Medicine and Epidemiology, BU School of Medicine, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Section of Preventive Medicine and Epidemiology, BU School of Medicine, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A85">Department of Epidemiology, BU School of Public Health, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, BU School of Public Health, Boston, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Goel, Anuj" sort="Goel, Anuj" uniqKey="Goel A" first="Anuj" last="Goel">Anuj Goel</name>
<affiliation wicri:level="1"><nlm:aff id="A86">Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Groop, Leif" sort="Groop, Leif" uniqKey="Groop L" first="Leif" last="Groop">Leif Groop</name>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A24">Lund University Diabetes Centre, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Lund University Diabetes Centre, Malmö</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name>
<affiliation wicri:level="1"><nlm:aff id="A44">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A45">University of Iceland, Reykjavik, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>University of Iceland, Reykjavik</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hallmans, Goran" sort="Hallmans, Goran" uniqKey="Hallmans G" first="Göran" last="Hallmans">Göran Hallmans</name>
<affiliation wicri:level="1"><nlm:aff id="A87">Department of Public Health & Clinical Medicine, Nutrition Research, Umeå University, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Public Health & Clinical Medicine, Nutrition Research, Umeå University</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name>
<affiliation wicri:level="1"><nlm:aff id="A37">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hansson, Ola" sort="Hansson, Ola" uniqKey="Hansson O" first="Ola" last="Hansson">Ola Hansson</name>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A24">Lund University Diabetes Centre, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Lund University Diabetes Centre, Malmö</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B." last="Harris">Tamara B. Harris</name>
<affiliation wicri:level="1"><nlm:aff id="A88">Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name>
<affiliation wicri:level="1"><nlm:aff id="A29">MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Heath, Simon" sort="Heath, Simon" uniqKey="Heath S" first="Simon" last="Heath">Simon Heath</name>
<affiliation wicri:level="1"><nlm:aff id="A89">Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hercberg, Serge" sort="Hercberg, Serge" uniqKey="Hercberg S" first="Serge" last="Hercberg">Serge Hercberg</name>
<affiliation wicri:level="1"><nlm:aff id="A83">Institut National de la Santé et de la Recherche Médicale, Université Paris, Bobigny Cedex, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National de la Santé et de la Recherche Médicale, Université Paris, Bobigny Cedex</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hicks, Andrew A" sort="Hicks, Andrew A" uniqKey="Hicks A" first="Andrew A." last="Hicks">Andrew A. Hicks</name>
<affiliation wicri:level="1"><nlm:aff id="A90">Center for Biomedicine, European Academy Bozen/Bolzano, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Center for Biomedicine, European Academy Bozen/Bolzano, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hingorani, Aroon" sort="Hingorani, Aroon" uniqKey="Hingorani A" first="Aroon" last="Hingorani">Aroon Hingorani</name>
<affiliation wicri:level="1"><nlm:aff id="A91">Genetic epidemiology group, University College London, Department of Epidemiology & Public Health, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Genetic epidemiology group, University College London, Department of Epidemiology & Public Health, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A40">Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name>
<affiliation wicri:level="1"><nlm:aff id="A52">PathWest Laboratory Medicine of WA, J Block, QEII Medical Centre, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>PathWest Laboratory Medicine of WA, J Block, QEII Medical Centre, Nedlands</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A53">School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A54">Busselton Population Medical Research Foundation, B Block, QEII Medical Centre, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Busselton Population Medical Research Foundation, B Block, QEII Medical Centre, Nedlands</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A92">School of Population Health, The University of Western Australia, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Population Health, The University of Western Australia, Nedlands</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hung, Joseph" sort="Hung, Joseph" uniqKey="Hung J" first="Joseph" last="Hung">Joseph Hung</name>
<affiliation wicri:level="1"><nlm:aff id="A54">Busselton Population Medical Research Foundation, B Block, QEII Medical Centre, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Busselton Population Medical Research Foundation, B Block, QEII Medical Centre, Nedlands</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A93">Sir Charles Gairdner Hospital Unit, School of Medicine & Pharmacology, University of Western Australia, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Sir Charles Gairdner Hospital Unit, School of Medicine & Pharmacology, University of Western Australia</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jarvelin, Marjo Riitta" sort="Jarvelin, Marjo Riitta" uniqKey="Jarvelin M" first="Marjo Riitta" last="Jarvelin">Marjo Riitta Jarvelin</name>
<affiliation wicri:level="1"><nlm:aff id="A94">Department of Epidemiology and Biostatistics, School of Public Health, MRC-HPA Centre for Environment and Health, Faculty of Medicine, Imperial College London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, MRC-HPA Centre for Environment and Health, Faculty of Medicine, Imperial College London</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A95">Institute of Health Sciences, University of Oulu, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Health Sciences, University of Oulu, Oulu</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A96">Biocenter Oulu, University of Oulu, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A97">National Institute of Health and Welfare, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>National Institute of Health and Welfare, Oulu</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jhun, Min A" sort="Jhun, Min A" uniqKey="Jhun M" first="Min A." last="Jhun">Min A. Jhun</name>
<affiliation wicri:level="1"><nlm:aff id="A12">Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Johnson, Paul C D" sort="Johnson, Paul C D" uniqKey="Johnson P" first="Paul C. D." last="Johnson">Paul C. D. Johnson</name>
<affiliation wicri:level="1"><nlm:aff id="A76">Robertson Centre for Biostatistics, University of Glasgow, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Robertson Centre for Biostatistics, University of Glasgow</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name>
<affiliation wicri:level="1"><nlm:aff id="A98">Department of Cardiology C5-P, Leiden University Medical Center, Leiden, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology C5-P, Leiden University Medical Center, Leiden</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A99">Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Durrer Center for Cardiogenetic Research, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jula, Antti" sort="Jula, Antti" uniqKey="Jula A" first="Antti" last="Jula">Antti Jula</name>
<affiliation wicri:level="1"><nlm:aff id="A33">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kao, W H" sort="Kao, W H" uniqKey="Kao W" first="W. H." last="Kao">W. H. Kao</name>
<affiliation wicri:level="1"><nlm:aff id="A100">Division of Epidemiology, Johns Hopkins School of Public Health, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Epidemiology, Johns Hopkins School of Public Health, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kaprio, Jaakko" sort="Kaprio, Jaakko" uniqKey="Kaprio J" first="Jaakko" last="Kaprio">Jaakko Kaprio</name>
<affiliation wicri:level="1"><nlm:aff id="A74">National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A101">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A102">Hjelt Institute, Dept of Public Health, University of Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Hjelt Institute, Dept of Public Health, University of Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kardia, Sharon L R" sort="Kardia, Sharon L R" uniqKey="Kardia S" first="Sharon L. R." last="Kardia">Sharon L. R. Kardia</name>
<affiliation wicri:level="1"><nlm:aff id="A12">Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Keinanen Kiukaanniemi, Sirkka" sort="Keinanen Kiukaanniemi, Sirkka" uniqKey="Keinanen Kiukaanniemi S" first="Sirkka" last="Keinanen-Kiukaanniemi">Sirkka Keinanen-Kiukaanniemi</name>
<affiliation wicri:level="1"><nlm:aff id="A103">Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A104">Unit of General Practice, Oulu University Hospital, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Unit of General Practice, Oulu University Hospital, Oulu</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kivimaki, Mika" sort="Kivimaki, Mika" uniqKey="Kivimaki M" first="Mika" last="Kivimaki">Mika Kivimaki</name>
<affiliation wicri:level="1"><nlm:aff id="A62">University College London, Department of Epidemiology & Public Health, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>University College London, Department of Epidemiology & Public Health, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name>
<affiliation wicri:level="1"><nlm:aff id="A105">Department of Public Health, Faculty of Medicine, University of Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kovacs, Peter" sort="Kovacs, Peter" uniqKey="Kovacs P" first="Peter" last="Kovacs">Peter Kovacs</name>
<affiliation wicri:level="1"><nlm:aff id="A106">Interdisciplinary Centre for Clinical Research, University of Leipzig, Leipzig, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Interdisciplinary Centre for Clinical Research, University of Leipzig, Leipzig</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name>
<affiliation wicri:level="1"><nlm:aff id="A91">Genetic epidemiology group, University College London, Department of Epidemiology & Public Health, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Genetic epidemiology group, University College London, Department of Epidemiology & Public Health, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kuusisto, Johanna" sort="Kuusisto, Johanna" uniqKey="Kuusisto J" first="Johanna" last="Kuusisto">Johanna Kuusisto</name>
<affiliation wicri:level="1"><nlm:aff id="A107">Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kyvik, Kirsten Ohm" sort="Kyvik, Kirsten Ohm" uniqKey="Kyvik K" first="Kirsten Ohm" last="Kyvik">Kirsten Ohm Kyvik</name>
<affiliation><nlm:aff id="A108">Institute of Regional Health Services Research and Professor Odense Patient data Explorative Network (OPEN)</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Laakso, Markku" sort="Laakso, Markku" uniqKey="Laakso M" first="Markku" last="Laakso">Markku Laakso</name>
<affiliation wicri:level="1"><nlm:aff id="A107">Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lakka, Timo" sort="Lakka, Timo" uniqKey="Lakka T" first="Timo" last="Lakka">Timo Lakka</name>
<affiliation wicri:level="1"><nlm:aff id="A46">Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Kuopio</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A109">Kuopio Research Institute of Exercise Medicine, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Kuopio Research Institute of Exercise Medicine, Kuopio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lannfelt, Lars" sort="Lannfelt, Lars" uniqKey="Lannfelt L" first="Lars" last="Lannfelt">Lars Lannfelt</name>
<affiliation wicri:level="1"><nlm:aff id="A110">Department of Public Health and Caring Sciences, Uppsala University, Rudbecklaboratoriet, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Public Health and Caring Sciences, Uppsala University, Rudbecklaboratoriet, Uppsala</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lathrop, G Mark" sort="Lathrop, G Mark" uniqKey="Lathrop G" first="G Mark" last="Lathrop">G Mark Lathrop</name>
<affiliation wicri:level="1"><nlm:aff id="A89">Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J." last="Launer">Lenore J. Launer</name>
<affiliation wicri:level="1"><nlm:aff id="A88">Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Leander, Karin" sort="Leander, Karin" uniqKey="Leander K" first="Karin" last="Leander">Karin Leander</name>
<affiliation wicri:level="1"><nlm:aff id="A68">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, Guo" sort="Li, Guo" uniqKey="Li G" first="Guo" last="Li">Guo Li</name>
<affiliation wicri:level="1"><nlm:aff id="A111">Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name>
<affiliation wicri:level="1"><nlm:aff id="A112">Department of Medical Sciences, University Hospital, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, University Hospital, Uppsala University, Uppsala</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lindstrom, Jaana" sort="Lindstrom, Jaana" uniqKey="Lindstrom J" first="Jaana" last="Lindstrom">Jaana Lindstrom</name>
<affiliation wicri:level="1"><nlm:aff id="A113">Diabetes Prevention Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Diabetes Prevention Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lobbens, Stephane" sort="Lobbens, Stephane" uniqKey="Lobbens S" first="Stéphane" last="Lobbens">Stéphane Lobbens</name>
<affiliation wicri:level="1"><nlm:aff id="A9">Institut Pasteur de Lille, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A10">Lille Nord de France University, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Lille Nord de France University, Lille</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J. F." last="Loos">Ruth J. F. Loos</name>
<affiliation wicri:level="1"><nlm:aff id="A7">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Luan, Jian N" sort="Luan, Jian N" uniqKey="Luan J" first="Jian N" last="Luan">Jian N Luan</name>
<affiliation wicri:level="1"><nlm:aff id="A7">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lyssenko, Valeriya" sort="Lyssenko, Valeriya" uniqKey="Lyssenko V" first="Valeriya" last="Lyssenko">Valeriya Lyssenko</name>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A24">Lund University Diabetes Centre, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Lund University Diabetes Centre, Malmö</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name>
<affiliation wicri:level="1"><nlm:aff id="A13">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A14">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A114">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff>
<country xml:lang="fr">Estonie</country>
<wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Magnusson, Patrik K E" sort="Magnusson, Patrik K E" uniqKey="Magnusson P" first="Patrik K. E." last="Magnusson">Patrik K. E. Magnusson</name>
<affiliation wicri:level="1"><nlm:aff id="A19">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Marmot, Michael" sort="Marmot, Michael" uniqKey="Marmot M" first="Michael" last="Marmot">Michael Marmot</name>
<affiliation wicri:level="1"><nlm:aff id="A62">University College London, Department of Epidemiology & Public Health, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>University College London, Department of Epidemiology & Public Health, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Meneton, Pierre" sort="Meneton, Pierre" uniqKey="Meneton P" first="Pierre" last="Meneton">Pierre Meneton</name>
<affiliation wicri:level="1"><nlm:aff id="A115">Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mohlke, Karen L" sort="Mohlke, Karen L" uniqKey="Mohlke K" first="Karen L." last="Mohlke">Karen L. Mohlke</name>
<affiliation wicri:level="1"><nlm:aff id="A116">Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mooser, Vincent" sort="Mooser, Vincent" uniqKey="Mooser V" first="Vincent" last="Mooser">Vincent Mooser</name>
<affiliation wicri:level="1"><nlm:aff id="A117">Division of Genetics, GlaxoSmithKline, Philadelphia, Pennsylvania, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Genetics, GlaxoSmithKline, Philadelphia, Pennsylvania</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Morken, Mario A" sort="Morken, Mario A" uniqKey="Morken M" first="Mario A." last="Morken">Mario A. Morken</name>
<affiliation wicri:level="1"><nlm:aff id="A59">Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Miljkovic, Iva" sort="Miljkovic, Iva" uniqKey="Miljkovic I" first="Iva" last="Miljkovic">Iva Miljkovic</name>
<affiliation wicri:level="1"><nlm:aff id="A118">Department of Epidemiology, Center for Aging and Population Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, Center for Aging and Population Health, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Narisu, Narisu" sort="Narisu, Narisu" uniqKey="Narisu N" first="Narisu" last="Narisu">Narisu Narisu</name>
<affiliation wicri:level="1"><nlm:aff id="A59">Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="O Onnell, Jeff" sort="O Onnell, Jeff" uniqKey="O Onnell J" first="Jeff" last="O Onnell">Jeff O Onnell</name>
<affiliation wicri:level="1"><nlm:aff id="A28">Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ong, Ken K" sort="Ong, Ken K" uniqKey="Ong K" first="Ken K." last="Ong">Ken K. Ong</name>
<affiliation wicri:level="1"><nlm:aff id="A7">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A." last="Oostra">Ben A. Oostra</name>
<affiliation wicri:level="1"><nlm:aff id="A119">Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Clinical Genetics, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Palmer, Lyle J" sort="Palmer, Lyle J" uniqKey="Palmer L" first="Lyle J." last="Palmer">Lyle J. Palmer</name>
<affiliation wicri:level="1"><nlm:aff id="A16">Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research. Toronto, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research. Toronto</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A17">Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A22">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A101">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A120">Department of Medical Genetics, University of Helsinki and Helsinki University Central Hospital, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Medical Genetics, University of Helsinki and Helsinki University Central Hospital</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pankow, James S" sort="Pankow, James S" uniqKey="Pankow J" first="James S." last="Pankow">James S. Pankow</name>
<affiliation wicri:level="1"><nlm:aff id="A121">Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, Minnesota, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, Minnesota</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peden, John F" sort="Peden, John F" uniqKey="Peden J" first="John F." last="Peden">John F. Peden</name>
<affiliation wicri:level="1"><nlm:aff id="A86">Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pedersen, Nancy L" sort="Pedersen, Nancy L" uniqKey="Pedersen N" first="Nancy L." last="Pedersen">Nancy L. Pedersen</name>
<affiliation wicri:level="1"><nlm:aff id="A19">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pehlic, Marina" sort="Pehlic, Marina" uniqKey="Pehlic M" first="Marina" last="Pehlic">Marina Pehlic</name>
<affiliation wicri:level="1"><nlm:aff id="A122">Department of Biology, Faculty of Medicine, University of Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Department of Biology, Faculty of Medicine, University of Split</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peltonen, Leena" sort="Peltonen, Leena" uniqKey="Peltonen L" first="Leena" last="Peltonen">Leena Peltonen</name>
<affiliation wicri:level="1"><nlm:aff id="A22">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A101">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Penninx, Brenda" sort="Penninx, Brenda" uniqKey="Penninx B" first="Brenda" last="Penninx">Brenda Penninx</name>
<affiliation wicri:level="1"><nlm:aff id="A123">Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Psychiatry, Leiden University Medical Center, Leiden</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A124">Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A125">Department Psychiatry, EMGO Institute for Health and Care Research and Institute for Neurosciences, VU University Medical Center, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department Psychiatry, EMGO Institute for Health and Care Research and Institute for Neurosciences, VU University Medical Center, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pericic, Marijana" sort="Pericic, Marijana" uniqKey="Pericic M" first="Marijana" last="Pericic">Marijana Pericic</name>
<affiliation wicri:level="1"><nlm:aff id="A126">Institute for Anthropological Research, Zagreb, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Institute for Anthropological Research, Zagreb</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Perola, Markus" sort="Perola, Markus" uniqKey="Perola M" first="Markus" last="Perola">Markus Perola</name>
<affiliation wicri:level="1"><nlm:aff id="A33">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Perusse, Louis" sort="Perusse, Louis" uniqKey="Perusse L" first="Louis" last="Perusse">Louis Perusse</name>
<affiliation wicri:level="1"><nlm:aff id="A127">Department of Preventive Medicine, Laval University, Quebec, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Preventive Medicine, Laval University, Quebec</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peyser, Patricia A" sort="Peyser, Patricia A" uniqKey="Peyser P" first="Patricia A" last="Peyser">Patricia A. Peyser</name>
<affiliation wicri:level="1"><nlm:aff id="A12">Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name>
<affiliation wicri:level="1"><nlm:aff id="A105">Department of Public Health, Faculty of Medicine, University of Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pramstaller, Peter P" sort="Pramstaller, Peter P" uniqKey="Pramstaller P" first="Peter P." last="Pramstaller">Peter P. Pramstaller</name>
<affiliation wicri:level="1"><nlm:aff id="A90">Center for Biomedicine, European Academy Bozen/Bolzano, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Center for Biomedicine, European Academy Bozen/Bolzano, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Province, Michael A" sort="Province, Michael A" uniqKey="Province M" first="Michael A." last="Province">Michael A. Province</name>
<affiliation wicri:level="1"><nlm:aff id="A41">Department of Genetics Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Genetics Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="R Ikkonen, Katri" sort="R Ikkonen, Katri" uniqKey="R Ikkonen K" first="Katri" last="R Ikkönen">Katri R Ikkönen</name>
<affiliation wicri:level="1"><nlm:aff id="A25">Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rauramaa, Rainer" sort="Rauramaa, Rainer" uniqKey="Rauramaa R" first="Rainer" last="Rauramaa">Rainer Rauramaa</name>
<affiliation wicri:level="1"><nlm:aff id="A109">Kuopio Research Institute of Exercise Medicine, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Kuopio Research Institute of Exercise Medicine, Kuopio</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A128">Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rehnberg, Emil" sort="Rehnberg, Emil" uniqKey="Rehnberg E" first="Emil" last="Rehnberg">Emil Rehnberg</name>
<affiliation wicri:level="1"><nlm:aff id="A19">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rice, Ken" sort="Rice, Ken" uniqKey="Rice K" first="Ken" last="Rice">Ken Rice</name>
<affiliation wicri:level="1"><nlm:aff id="A129">Department of Biostatistics, University of Washington, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biostatistics, University of Washington, Seattle, Washington</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I." last="Rotter">Jerome I. Rotter</name>
<affiliation><nlm:aff id="A130">Medical Genetics Institute, Cedars-Sinai Medical Center</nlm:aff>
<wicri:noCountry code="subfield">Cedars-Sinai Medical Center</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name>
<affiliation wicri:level="1"><nlm:aff id="A63">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A131">Centre for Global Health, University of Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Centre for Global Health, University of Split</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ruokonen, Aimo" sort="Ruokonen, Aimo" uniqKey="Ruokonen A" first="Aimo" last="Ruokonen">Aimo Ruokonen</name>
<affiliation wicri:level="1"><nlm:aff id="A132">Institute of Clinical Medicine, University of Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Clinical Medicine, University of Oulu</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Saaristo, Timo" sort="Saaristo, Timo" uniqKey="Saaristo T" first="Timo" last="Saaristo">Timo Saaristo</name>
<affiliation wicri:level="1"><nlm:aff id="A133">Finnish Diabetes Association, Tampere, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Finnish Diabetes Association, Tampere</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A134">Pirkanmaa Hospital District, Tampere, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Pirkanmaa Hospital District, Tampere</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sabater Lleal, Maria" sort="Sabater Lleal, Maria" uniqKey="Sabater Lleal M" first="Maria" last="Sabater-Lleal">Maria Sabater-Lleal</name>
<affiliation wicri:level="1"><nlm:aff id="A37">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name>
<affiliation wicri:level="1"><nlm:aff id="A33">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Savage, David B" sort="Savage, David B" uniqKey="Savage D" first="David B." last="Savage">David B. Savage</name>
<affiliation wicri:level="1"><nlm:aff id="A135">Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Saxena, Richa" sort="Saxena, Richa" uniqKey="Saxena R" first="Richa" last="Saxena">Richa Saxena</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A136">Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schwarz, Peter" sort="Schwarz, Peter" uniqKey="Schwarz P" first="Peter" last="Schwarz">Peter Schwarz</name>
<affiliation wicri:level="1"><nlm:aff id="A137">Department of Medicine, Division Prevention and Care of Diabetes, University of Dresden, Dresden, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Medicine, Division Prevention and Care of Diabetes, University of Dresden, Dresden</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Seedorf, Udo" sort="Seedorf, Udo" uniqKey="Seedorf U" first="Udo" last="Seedorf">Udo Seedorf</name>
<affiliation wicri:level="1"><nlm:aff id="A138">Leibniz Institute for Arteriosclerosis Research, University of Munster, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Leibniz Institute for Arteriosclerosis Research, University of Munster</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sennblad, Bengt" sort="Sennblad, Bengt" uniqKey="Sennblad B" first="Bengt" last="Sennblad">Bengt Sennblad</name>
<affiliation wicri:level="1"><nlm:aff id="A37">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Serrano Rios, Manuel" sort="Serrano Rios, Manuel" uniqKey="Serrano Rios M" first="Manuel" last="Serrano-Rios">Manuel Serrano-Rios</name>
<affiliation wicri:level="1"><nlm:aff id="A27">Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R." last="Shuldiner">Alan R. Shuldiner</name>
<affiliation wicri:level="1"><nlm:aff id="A28">Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A139">Geriatric Research and Education Clinical Center, Veterans Administration Medical Center, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Geriatric Research and Education Clinical Center, Veterans Administration Medical Center, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sijbrands, Eric J G" sort="Sijbrands, Eric J G" uniqKey="Sijbrands E" first="Eric J. G." last="Sijbrands">Eric J. G. Sijbrands</name>
<affiliation wicri:level="1"><nlm:aff id="A140">Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Internal Medicine, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Siscovick, David S" sort="Siscovick, David S" uniqKey="Siscovick D" first="David S." last="Siscovick">David S. Siscovick</name>
<affiliation wicri:level="1"><nlm:aff id="A111">Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A141">Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A142">Department of Epidemiology, University of Washington, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Smit, Johannes H" sort="Smit, Johannes H" uniqKey="Smit J" first="Johannes H." last="Smit">Johannes H. Smit</name>
<affiliation wicri:level="1"><nlm:aff id="A143">Department of Psychiatry, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Psychiatry, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Small, Kerrin S" sort="Small, Kerrin S" uniqKey="Small K" first="Kerrin S." last="Small">Kerrin S. Small</name>
<affiliation wicri:level="1"><nlm:aff id="A31">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Smith, Nicholas L" sort="Smith, Nicholas L" uniqKey="Smith N" first="Nicholas L." last="Smith">Nicholas L. Smith</name>
<affiliation wicri:level="1"><nlm:aff id="A141">Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A142">Department of Epidemiology, University of Washington, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A144">Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Group Health Research Institute, Group Health Cooperative, Seattle, Washington</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A145">Seattle Epidemiologic Research and Information Center, Veterans Affairs Office of Research and Development, Seattle, WA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Seattle Epidemiologic Research and Information Center, Veterans Affairs Office of Research and Development, Seattle, WA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Smith, Albert Vernon" sort="Smith, Albert Vernon" uniqKey="Smith A" first="Albert Vernon" last="Smith">Albert Vernon Smith</name>
<affiliation wicri:level="1"><nlm:aff id="A44">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A45">University of Iceland, Reykjavik, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>University of Iceland, Reykjavik</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stan Kova, Alena" sort="Stan Kova, Alena" uniqKey="Stan Kova A" first="Alena" last="Stan Ková">Alena Stan Ková</name>
<affiliation wicri:level="1"><nlm:aff id="A107">Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stirrups, Kathleen" sort="Stirrups, Kathleen" uniqKey="Stirrups K" first="Kathleen" last="Stirrups">Kathleen Stirrups</name>
<affiliation wicri:level="1"><nlm:aff id="A22">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stumvoll, Michael" sort="Stumvoll, Michael" uniqKey="Stumvoll M" first="Michael" last="Stumvoll">Michael Stumvoll</name>
<affiliation wicri:level="1"><nlm:aff id="A60">IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>IFB Adiposity Diseases, University of Leipzig, Leipzig</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A146">Department of Medicine, University of Leipzig, Division of Endocrinology and Diabetes, Leipzig, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Medicine, University of Leipzig, Division of Endocrinology and Diabetes, Leipzig</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sun, Yan V" sort="Sun, Yan V" uniqKey="Sun Y" first="Yan V." last="Sun">Yan V. Sun</name>
<affiliation wicri:level="1"><nlm:aff id="A147">Department of Epidemiology, Emory University, Atlanta, Georgia, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, Emory University, Atlanta, Georgia</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Swift, Amy J" sort="Swift, Amy J" uniqKey="Swift A" first="Amy J." last="Swift">Amy J. Swift</name>
<affiliation wicri:level="1"><nlm:aff id="A59">Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tonjes, Anke" sort="Tonjes, Anke" uniqKey="Tonjes A" first="Anke" last="Tönjes">Anke Tönjes</name>
<affiliation wicri:level="1"><nlm:aff id="A60">IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>IFB Adiposity Diseases, University of Leipzig, Leipzig</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A146">Department of Medicine, University of Leipzig, Division of Endocrinology and Diabetes, Leipzig, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Medicine, University of Leipzig, Division of Endocrinology and Diabetes, Leipzig</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name>
<affiliation wicri:level="1"><nlm:aff id="A148">Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A149">South Ostrobothnia Central Hospital, Seinäjoki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>South Ostrobothnia Central Hospital, Seinäjoki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A150">Hospital Universitario La Paz, Madrid, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Hospital Universitario La Paz, Madrid</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A151">Centre for Vascular Prevention, Danube-University Krems, Krems, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Centre for Vascular Prevention, Danube-University Krems, Krems</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name>
<affiliation wicri:level="1"><nlm:aff id="A98">Department of Cardiology C5-P, Leiden University Medical Center, Leiden, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology C5-P, Leiden University Medical Center, Leiden</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="Andre G." last="Uitterlinden">Andre G. Uitterlinden</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
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<wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea>
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<affiliation wicri:level="1"><nlm:aff id="A40">Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam, The Netherlands</nlm:aff>
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<wicri:regionArea>Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam</wicri:regionArea>
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<affiliation wicri:level="1"><nlm:aff id="A140">Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Internal Medicine, Erasmus MC, Rotterdam</wicri:regionArea>
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<author><name sortKey="Uusitupa, Matti" sort="Uusitupa, Matti" uniqKey="Uusitupa M" first="Matti" last="Uusitupa">Matti Uusitupa</name>
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<wicri:regionArea>Research Unit, Kuopio University Hospital, Kuopio</wicri:regionArea>
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<author><name sortKey="Vikstrom, Max" sort="Vikstrom, Max" uniqKey="Vikstrom M" first="Max" last="Vikström">Max Vikström</name>
<affiliation wicri:level="1"><nlm:aff id="A68">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea>
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<author><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name>
<affiliation wicri:level="1"><nlm:aff id="A29">MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh</wicri:regionArea>
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</author>
<author><name sortKey="Vohl, Marie Claude" sort="Vohl, Marie Claude" uniqKey="Vohl M" first="Marie-Claude" last="Vohl">Marie-Claude Vohl</name>
<affiliation wicri:level="1"><nlm:aff id="A154">Department of Food Science and Nutrition, Laval University, Quebec, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Food Science and Nutrition, Laval University, Quebec</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Voight, Benjamin F" sort="Voight, Benjamin F" uniqKey="Voight B" first="Benjamin F." last="Voight">Benjamin F. Voight</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
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</author>
<author><name sortKey="Vollenweider, Peter" sort="Vollenweider, Peter" uniqKey="Vollenweider P" first="Peter" last="Vollenweider">Peter Vollenweider</name>
<affiliation wicri:level="1"><nlm:aff id="A155">Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Waeber, Gerard" sort="Waeber, Gerard" uniqKey="Waeber G" first="Gerard" last="Waeber">Gerard Waeber</name>
<affiliation wicri:level="1"><nlm:aff id="A155">Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Waterworth, Dawn M" sort="Waterworth, Dawn M" uniqKey="Waterworth D" first="Dawn M" last="Waterworth">Dawn M. Waterworth</name>
<affiliation wicri:level="1"><nlm:aff id="A117">Division of Genetics, GlaxoSmithKline, Philadelphia, Pennsylvania, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Genetics, GlaxoSmithKline, Philadelphia, Pennsylvania</wicri:regionArea>
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</author>
<author><name sortKey="Watkins, Hugh" sort="Watkins, Hugh" uniqKey="Watkins H" first="Hugh" last="Watkins">Hugh Watkins</name>
<affiliation wicri:level="1"><nlm:aff id="A86">Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wheeler, Eleanor" sort="Wheeler, Eleanor" uniqKey="Wheeler E" first="Eleanor" last="Wheeler">Eleanor Wheeler</name>
<affiliation wicri:level="1"><nlm:aff id="A156">Metabolic Disease Group, Wellcome Trust Sanger Institute, Hinxton, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Metabolic Disease Group, Wellcome Trust Sanger Institute, Hinxton</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Widen, Elisabeth" sort="Widen, Elisabeth" uniqKey="Widen E" first="Elisabeth" last="Widen">Elisabeth Widen</name>
<affiliation wicri:level="1"><nlm:aff id="A157">Institute for Molecular Medicine Finland, University of Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wild, Sarah H" sort="Wild, Sarah H" uniqKey="Wild S" first="Sarah H." last="Wild">Sarah H. Wild</name>
<affiliation wicri:level="1"><nlm:aff id="A63">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Willems, Sara M" sort="Willems, Sara M" uniqKey="Willems S" first="Sara M." last="Willems">Sara M. Willems</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name>
<affiliation wicri:level="1"><nlm:aff id="A18">Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F." last="Wilson">James F. Wilson</name>
<affiliation wicri:level="1"><nlm:aff id="A63">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Witteman, Jacqueline C M" sort="Witteman, Jacqueline C M" uniqKey="Witteman J" first="Jacqueline C. M." last="Witteman">Jacqueline C. M. Witteman</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A40">Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F." last="Wright">Alan F. Wright</name>
<affiliation wicri:level="1"><nlm:aff id="A29">MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yaghootkar, Hanieh" sort="Yaghootkar, Hanieh" uniqKey="Yaghootkar H" first="Hanieh" last="Yaghootkar">Hanieh Yaghootkar</name>
<affiliation wicri:level="1"><nlm:aff id="A30">Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter</wicri:regionArea>
</affiliation>
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<author><name sortKey="Zelenika, Diana" sort="Zelenika, Diana" uniqKey="Zelenika D" first="Diana" last="Zelenika">Diana Zelenika</name>
<affiliation wicri:level="1"><nlm:aff id="A89">Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry</wicri:regionArea>
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</author>
<author><name sortKey="Zemunik, Tatijana" sort="Zemunik, Tatijana" uniqKey="Zemunik T" first="Tatijana" last="Zemunik">Tatijana Zemunik</name>
<affiliation wicri:level="1"><nlm:aff id="A122">Department of Biology, Faculty of Medicine, University of Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Department of Biology, Faculty of Medicine, University of Split</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zgaga, Lina" sort="Zgaga, Lina" uniqKey="Zgaga L" first="Lina" last="Zgaga">Lina Zgaga</name>
<affiliation wicri:level="1"><nlm:aff id="A63">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A158">Department of medical statistics, epidemiology and medical informatics, University of Zagreb, Zagreb, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Department of medical statistics, epidemiology and medical informatics, University of Zagreb, Zagreb</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J." last="Wareham">Nicholas J. Wareham</name>
<affiliation wicri:level="1"><nlm:aff id="A7">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I." last="Mccarthy">Mark I. Mccarthy</name>
<affiliation wicri:level="1"><nlm:aff id="A13">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A14">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A159">Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Ines" last="Barroso">Ines Barroso</name>
<affiliation wicri:level="1"><nlm:aff id="A156">Metabolic Disease Group, Wellcome Trust Sanger Institute, Hinxton, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Metabolic Disease Group, Wellcome Trust Sanger Institute, Hinxton</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A160">University of Cambridge, Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>University of Cambridge, Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Watanabe, Richard M" sort="Watanabe, Richard M" uniqKey="Watanabe R" first="Richard M." last="Watanabe">Richard M. Watanabe</name>
<affiliation wicri:level="1"><nlm:aff id="A56">Department of Physiology & Biophysics, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Physiology & Biophysics, Keck School of Medicine of the University of Southern California, Los Angeles, California</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A161">Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Florez, Jose C" sort="Florez, Jose C" uniqKey="Florez J" first="Jose C." last="Florez">Jose C. Florez</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
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<affiliation wicri:level="1"><nlm:aff id="A8">Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Harvard Medical School, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A136">Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A162">Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dupuis, Josee" sort="Dupuis, Josee" uniqKey="Dupuis J" first="Josée" last="Dupuis">Josée Dupuis</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A77">National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Meigs, James B" sort="Meigs, James B" uniqKey="Meigs J" first="James B." last="Meigs">James B. Meigs</name>
<affiliation wicri:level="1"><nlm:aff id="A5">General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A8">Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Harvard Medical School, Boston, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name>
<affiliation wicri:level="1"><nlm:aff id="A7">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance</title>
<author><name sortKey="Manning, Alisa K" sort="Manning, Alisa K" uniqKey="Manning A" first="Alisa K." last="Manning">Alisa K. Manning</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A2">Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A3">Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4">Harvard Medical School, Boston, Massachusetts</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Harvard Medical School, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hivert, Marie France" sort="Hivert, Marie France" uniqKey="Hivert M" first="Marie-France" last="Hivert">Marie-France Hivert</name>
<affiliation wicri:level="1"><nlm:aff id="A5">General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A6">Department of Medicine, Universite de Sherbrooke, Sherbrooke, Québec, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Medicine, Universite de Sherbrooke, Sherbrooke, Québec</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Scott, Robert A" sort="Scott, Robert A" uniqKey="Scott R" first="Robert A." last="Scott">Robert A. Scott</name>
<affiliation wicri:level="1"><nlm:aff id="A7">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Grimsby, Jonna L" sort="Grimsby, Jonna L" uniqKey="Grimsby J" first="Jonna L." last="Grimsby">Jonna L. Grimsby</name>
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<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea>
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<affiliation wicri:level="1"><nlm:aff id="A8">Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Harvard Medical School, Boston, Massachusetts</wicri:regionArea>
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</author>
<author><name sortKey="Bouatia Naji, Nabila" sort="Bouatia Naji, Nabila" uniqKey="Bouatia Naji N" first="Nabila" last="Bouatia-Naji">Nabila Bouatia-Naji</name>
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<country xml:lang="fr">France</country>
<wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea>
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<affiliation wicri:level="1"><nlm:aff id="A10">Lille Nord de France University, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Lille Nord de France University, Lille</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chen, Han" sort="Chen, Han" uniqKey="Chen H" first="Han" last="Chen">Han Chen</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rybin, Denis" sort="Rybin, Denis" uniqKey="Rybin D" first="Denis" last="Rybin">Denis Rybin</name>
<affiliation wicri:level="1"><nlm:aff id="A11">Boston University Data Coordinating Center, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Boston University Data Coordinating Center, Boston, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Liu, Ching Ti" sort="Liu, Ching Ti" uniqKey="Liu C" first="Ching-Ti" last="Liu">Ching-Ti Liu</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bielak, Lawrence F" sort="Bielak, Lawrence F" uniqKey="Bielak L" first="Lawrence F." last="Bielak">Lawrence F. Bielak</name>
<affiliation wicri:level="1"><nlm:aff id="A12">Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name>
<affiliation wicri:level="1"><nlm:aff id="A13">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A14">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amin, Najaf" sort="Amin, Najaf" uniqKey="Amin N" first="Najaf" last="Amin">Najaf Amin</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Barnes, Daniel" sort="Barnes, Daniel" uniqKey="Barnes D" first="Daniel" last="Barnes">Daniel Barnes</name>
<affiliation wicri:level="1"><nlm:aff id="A7">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Cadby, Gemma" sort="Cadby, Gemma" uniqKey="Cadby G" first="Gemma" last="Cadby">Gemma Cadby</name>
<affiliation wicri:level="1"><nlm:aff id="A16">Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research. Toronto, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research. Toronto</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A17">Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name>
<affiliation wicri:level="1"><nlm:aff id="A18">Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name>
<affiliation wicri:level="1"><nlm:aff id="A19">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U." last="Jackson">Anne U. Jackson</name>
<affiliation wicri:level="1"><nlm:aff id="A20">Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Johnson, Toby" sort="Johnson, Toby" uniqKey="Johnson T" first="Toby" last="Johnson">Toby Johnson</name>
<affiliation wicri:level="1"><nlm:aff id="A21">Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kanoni, Stavroula" sort="Kanoni, Stavroula" uniqKey="Kanoni S" first="Stavroula" last="Kanoni">Stavroula Kanoni</name>
<affiliation wicri:level="1"><nlm:aff id="A22">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ladenvall, Claes" sort="Ladenvall, Claes" uniqKey="Ladenvall C" first="Claes" last="Ladenvall">Claes Ladenvall</name>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A24">Lund University Diabetes Centre, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Lund University Diabetes Centre, Malmö</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lagou, Vasiliki" sort="Lagou, Vasiliki" uniqKey="Lagou V" first="Vasiliki" last="Lagou">Vasiliki Lagou</name>
<affiliation wicri:level="1"><nlm:aff id="A13">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A14">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lahti, Jari" sort="Lahti, Jari" uniqKey="Lahti J" first="Jari" last="Lahti">Jari Lahti</name>
<affiliation wicri:level="1"><nlm:aff id="A25">Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lecoeur, Cecile" sort="Lecoeur, Cecile" uniqKey="Lecoeur C" first="Cecile" last="Lecoeur">Cecile Lecoeur</name>
<affiliation wicri:level="1"><nlm:aff id="A9">Institut Pasteur de Lille, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A10">Lille Nord de France University, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Lille Nord de France University, Lille</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Liu, Yongmei" sort="Liu, Yongmei" uniqKey="Liu Y" first="Yongmei" last="Liu">Yongmei Liu</name>
<affiliation wicri:level="1"><nlm:aff id="A26">Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Martinez Larrad, Maria Teresa" sort="Martinez Larrad, Maria Teresa" uniqKey="Martinez Larrad M" first="Maria Teresa" last="Martinez-Larrad">Maria Teresa Martinez-Larrad</name>
<affiliation wicri:level="1"><nlm:aff id="A27">Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Montasser, May E" sort="Montasser, May E" uniqKey="Montasser M" first="May E." last="Montasser">May E. Montasser</name>
<affiliation wicri:level="1"><nlm:aff id="A28">Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Navarro, Pau" sort="Navarro, Pau" uniqKey="Navarro P" first="Pau" last="Navarro">Pau Navarro</name>
<affiliation wicri:level="1"><nlm:aff id="A29">MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Perry, John R B" sort="Perry, John R B" uniqKey="Perry J" first="John R. B." last="Perry">John R. B. Perry</name>
<affiliation wicri:level="1"><nlm:aff id="A14">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A30">Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A31">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rasmussen Torvik, Laura J" sort="Rasmussen Torvik, Laura J" uniqKey="Rasmussen Torvik L" first="Laura J." last="Rasmussen-Torvik">Laura J. Rasmussen-Torvik</name>
<affiliation wicri:level="1"><nlm:aff id="A32">Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Salo, Perttu" sort="Salo, Perttu" uniqKey="Salo P" first="Perttu" last="Salo">Perttu Salo</name>
<affiliation wicri:level="1"><nlm:aff id="A33">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sattar, Naveed" sort="Sattar, Naveed" uniqKey="Sattar N" first="Naveed" last="Sattar">Naveed Sattar</name>
<affiliation wicri:level="1"><nlm:aff id="A34">Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Cardiovascular and Medical Sciences, University of Glasgow</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shungin, Dmitry" sort="Shungin, Dmitry" uniqKey="Shungin D" first="Dmitry" last="Shungin">Dmitry Shungin</name>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A24">Lund University Diabetes Centre, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Lund University Diabetes Centre, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A35">Department of Public Health & Clinical Medicine, Genetic Epidemiology & Clinical Research Group, Umeå University Hospital, Umeå, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Public Health & Clinical Medicine, Genetic Epidemiology & Clinical Research Group, Umeå University Hospital, Umeå</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A36">Department of Odontology, Umeå University, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Odontology, Umeå University</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Strawbridge, Rona J" sort="Strawbridge, Rona J" uniqKey="Strawbridge R" first="Rona J." last="Strawbridge">Rona J. Strawbridge</name>
<affiliation wicri:level="1"><nlm:aff id="A37">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name>
<affiliation wicri:level="1"><nlm:aff id="A38">Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M." last="Van Duijn">Cornelia M. Van Duijn</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
<affiliation><nlm:aff id="A39">Centre for medical systems biology, Netherlands Genomics Initiative, The Hague</nlm:aff>
<wicri:noCountry code="subfield">The Hague</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A40">Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="An, Ping" sort="An, Ping" uniqKey="An P" first="Ping" last="An">Ping An</name>
<affiliation wicri:level="1"><nlm:aff id="A41">Department of Genetics Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Genetics Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Andrade, Mariza" sort="De Andrade, Mariza" uniqKey="De Andrade M" first="Mariza" last="De Andrade">Mariza De Andrade</name>
<affiliation wicri:level="1"><nlm:aff id="A42">Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Andrews, Jeanette S" sort="Andrews, Jeanette S" uniqKey="Andrews J" first="Jeanette S." last="Andrews">Jeanette S. Andrews</name>
<affiliation wicri:level="1"><nlm:aff id="A43">Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Aspelund, Thor" sort="Aspelund, Thor" uniqKey="Aspelund T" first="Thor" last="Aspelund">Thor Aspelund</name>
<affiliation wicri:level="1"><nlm:aff id="A44">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A45">University of Iceland, Reykjavik, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>University of Iceland, Reykjavik</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Atalay, Mustafa" sort="Atalay, Mustafa" uniqKey="Atalay M" first="Mustafa" last="Atalay">Mustafa Atalay</name>
<affiliation wicri:level="1"><nlm:aff id="A46">Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Kuopio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Aulchenko, Yurii" sort="Aulchenko, Yurii" uniqKey="Aulchenko Y" first="Yurii" last="Aulchenko">Yurii Aulchenko</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Balkau, Beverley" sort="Balkau, Beverley" uniqKey="Balkau B" first="Beverley" last="Balkau">Beverley Balkau</name>
<affiliation wicri:level="1"><nlm:aff id="A47">Inserm, CESP Centre for research in Epidemiology and Population Health, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Inserm, CESP Centre for research in Epidemiology and Population Health, Villejuif</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A48">University Paris Sud 11, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>University Paris Sud 11, Villejuif</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bandinelli, Stefania" sort="Bandinelli, Stefania" uniqKey="Bandinelli S" first="Stefania" last="Bandinelli">Stefania Bandinelli</name>
<affiliation wicri:level="1"><nlm:aff id="A49">Geriatric Unit, Azienda Sanitaria di Firenze, Florence, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Geriatric Unit, Azienda Sanitaria di Firenze, Florence</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Beckmann, Jacques S" sort="Beckmann, Jacques S" uniqKey="Beckmann J" first="Jacques S." last="Beckmann">Jacques S. Beckmann</name>
<affiliation wicri:level="1"><nlm:aff id="A50">Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Medical Genetics, University of Lausanne, Lausanne</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A51">Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois, Lausanne</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Beilby, John P" sort="Beilby, John P" uniqKey="Beilby J" first="John P." last="Beilby">John P. Beilby</name>
<affiliation wicri:level="1"><nlm:aff id="A52">PathWest Laboratory Medicine of WA, J Block, QEII Medical Centre, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>PathWest Laboratory Medicine of WA, J Block, QEII Medical Centre, Nedlands</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A53">School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A54">Busselton Population Medical Research Foundation, B Block, QEII Medical Centre, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Busselton Population Medical Research Foundation, B Block, QEII Medical Centre, Nedlands</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bellis, Claire" sort="Bellis, Claire" uniqKey="Bellis C" first="Claire" last="Bellis">Claire Bellis</name>
<affiliation wicri:level="1"><nlm:aff id="A55">Texas Biomedical Research Institute, San Antonio, Texas, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Texas Biomedical Research Institute, San Antonio, Texas</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bergman, Richard N" sort="Bergman, Richard N" uniqKey="Bergman R" first="Richard N." last="Bergman">Richard N. Bergman</name>
<affiliation wicri:level="1"><nlm:aff id="A56">Department of Physiology & Biophysics, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Physiology & Biophysics, Keck School of Medicine of the University of Southern California, Los Angeles, California</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Blangero, John" sort="Blangero, John" uniqKey="Blangero J" first="John" last="Blangero">John Blangero</name>
<affiliation wicri:level="1"><nlm:aff id="A55">Texas Biomedical Research Institute, San Antonio, Texas, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Texas Biomedical Research Institute, San Antonio, Texas</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boban, Mladen" sort="Boban, Mladen" uniqKey="Boban M" first="Mladen" last="Boban">Mladen Boban</name>
<affiliation wicri:level="1"><nlm:aff id="A57">Department of Pharmacology, Faculty of Medicine, University of Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Department of Pharmacology, Faculty of Medicine, University of Split</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name>
<affiliation wicri:level="1"><nlm:aff id="A20">Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name>
<affiliation wicri:level="1"><nlm:aff id="A58">Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bonnycastle, Lori L" sort="Bonnycastle, Lori L" uniqKey="Bonnycastle L" first="Lori L." last="Bonnycastle">Lori L. Bonnycastle</name>
<affiliation wicri:level="1"><nlm:aff id="A59">Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I." last="Boomsma">Dorret I. Boomsma</name>
<affiliation wicri:level="1"><nlm:aff id="A18">Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Borecki, Ingrid B" sort="Borecki, Ingrid B" uniqKey="Borecki I" first="Ingrid B." last="Borecki">Ingrid B. Borecki</name>
<affiliation wicri:level="1"><nlm:aff id="A41">Department of Genetics Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Genetics Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bottcher, Yvonne" sort="Bottcher, Yvonne" uniqKey="Bottcher Y" first="Yvonne" last="Böttcher">Yvonne Böttcher</name>
<affiliation wicri:level="1"><nlm:aff id="A60">IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>IFB Adiposity Diseases, University of Leipzig, Leipzig</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bouchard, Claude" sort="Bouchard, Claude" uniqKey="Bouchard C" first="Claude" last="Bouchard">Claude Bouchard</name>
<affiliation wicri:level="1"><nlm:aff id="A61">Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Pennington Biomedical Research Center, Baton Rouge, Louisiana</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brunner, Eric" sort="Brunner, Eric" uniqKey="Brunner E" first="Eric" last="Brunner">Eric Brunner</name>
<affiliation wicri:level="1"><nlm:aff id="A62">University College London, Department of Epidemiology & Public Health, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>University College London, Department of Epidemiology & Public Health, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Budimir, Danijela" sort="Budimir, Danijela" uniqKey="Budimir D" first="Danijela" last="Budimir">Danijela Budimir</name>
<affiliation wicri:level="1"><nlm:aff id="A57">Department of Pharmacology, Faculty of Medicine, University of Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Department of Pharmacology, Faculty of Medicine, University of Split</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name>
<affiliation wicri:level="1"><nlm:aff id="A63">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Carlson, Olga" sort="Carlson, Olga" uniqKey="Carlson O" first="Olga" last="Carlson">Olga Carlson</name>
<affiliation wicri:level="1"><nlm:aff id="A64">Laboratory of Clinical Investigation, National Institute of Aging, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Laboratory of Clinical Investigation, National Institute of Aging, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chines, Peter S" sort="Chines, Peter S" uniqKey="Chines P" first="Peter S." last="Chines">Peter S. Chines</name>
<affiliation wicri:level="1"><nlm:aff id="A59">Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Clarke, Robert" sort="Clarke, Robert" uniqKey="Clarke R" first="Robert" last="Clarke">Robert Clarke</name>
<affiliation wicri:level="1"><nlm:aff id="A65">Clinical Trial Service Unit, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Clinical Trial Service Unit, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Collins, Francis S" sort="Collins, Francis S" uniqKey="Collins F" first="Francis S." last="Collins">Francis S. Collins</name>
<affiliation wicri:level="1"><nlm:aff id="A66">Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Corbat N Anchuelo, Arturo" sort="Corbat N Anchuelo, Arturo" uniqKey="Corbat N Anchuelo A" first="Arturo" last="Corbat N-Anchuelo">Arturo Corbat N-Anchuelo</name>
<affiliation wicri:level="1"><nlm:aff id="A27">Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Couper, David" sort="Couper, David" uniqKey="Couper D" first="David" last="Couper">David Couper</name>
<affiliation wicri:level="1"><nlm:aff id="A67">Department of Biostatistics, University of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biostatistics, University of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Faire, Ulf" sort="De Faire, Ulf" uniqKey="De Faire U" first="Ulf" last="De Faire">Ulf De Faire</name>
<affiliation wicri:level="1"><nlm:aff id="A68">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dedoussis, George V" sort="Dedoussis, George V" uniqKey="Dedoussis G" first="George V" last="Dedoussis">George V. Dedoussis</name>
<affiliation wicri:level="1"><nlm:aff id="A69">Department of Nutrition - Dietetics, Harokopio University, Athens, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Nutrition - Dietetics, Harokopio University, Athens</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name>
<affiliation wicri:level="1"><nlm:aff id="A22">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dimitriou, Maria" sort="Dimitriou, Maria" uniqKey="Dimitriou M" first="Maria" last="Dimitriou">Maria Dimitriou</name>
<affiliation wicri:level="1"><nlm:aff id="A69">Department of Nutrition - Dietetics, Harokopio University, Athens, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Nutrition - Dietetics, Harokopio University, Athens</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Egan, Josephine M" sort="Egan, Josephine M" uniqKey="Egan J" first="Josephine M" last="Egan">Josephine M. Egan</name>
<affiliation wicri:level="1"><nlm:aff id="A64">Laboratory of Clinical Investigation, National Institute of Aging, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Laboratory of Clinical Investigation, National Institute of Aging, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eiriksdottir, Gudny" sort="Eiriksdottir, Gudny" uniqKey="Eiriksdottir G" first="Gudny" last="Eiriksdottir">Gudny Eiriksdottir</name>
<affiliation wicri:level="1"><nlm:aff id="A44">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Erdos, Michael R" sort="Erdos, Michael R" uniqKey="Erdos M" first="Michael R." last="Erdos">Michael R. Erdos</name>
<affiliation wicri:level="1"><nlm:aff id="A59">Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G." last="Eriksson">Johan G. Eriksson</name>
<affiliation wicri:level="1"><nlm:aff id="A70">Department of General Practice and Primary health Care, University of Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of General Practice and Primary health Care, University of Helsinki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A71">Helsinki University Central Hospital, Unit of General Practice, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Helsinki University Central Hospital, Unit of General Practice, Helsinki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A72">Folkhalsan Research Centre, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Folkhalsan Research Centre, Helsinki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A73">Vaasa Central Hospital, Vaasa, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Vaasa Central Hospital, Vaasa</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A74">National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eury, Elodie" sort="Eury, Elodie" uniqKey="Eury E" first="Elodie" last="Eury">Elodie Eury</name>
<affiliation wicri:level="1"><nlm:aff id="A9">Institut Pasteur de Lille, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A10">Lille Nord de France University, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Lille Nord de France University, Lille</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name>
<affiliation wicri:level="1"><nlm:aff id="A75">Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ford, Ian" sort="Ford, Ian" uniqKey="Ford I" first="Ian" last="Ford">Ian Ford</name>
<affiliation wicri:level="1"><nlm:aff id="A76">Robertson Centre for Biostatistics, University of Glasgow, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Robertson Centre for Biostatistics, University of Glasgow</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Forouhi, Nita G" sort="Forouhi, Nita G" uniqKey="Forouhi N" first="Nita G." last="Forouhi">Nita G. Forouhi</name>
<affiliation wicri:level="1"><nlm:aff id="A7">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fox, Caroline S" sort="Fox, Caroline S" uniqKey="Fox C" first="Caroline S" last="Fox">Caroline S. Fox</name>
<affiliation wicri:level="1"><nlm:aff id="A77">National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A78">Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Franzosi, Maria Grazia" sort="Franzosi, Maria Grazia" uniqKey="Franzosi M" first="Maria Grazia" last="Franzosi">Maria Grazia Franzosi</name>
<affiliation wicri:level="1"><nlm:aff id="A79">Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research, Milan, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research, Milan</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Franks, Paul W" sort="Franks, Paul W" uniqKey="Franks P" first="Paul W" last="Franks">Paul W. Franks</name>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A24">Lund University Diabetes Centre, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Lund University Diabetes Centre, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A35">Department of Public Health & Clinical Medicine, Genetic Epidemiology & Clinical Research Group, Umeå University Hospital, Umeå, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Public Health & Clinical Medicine, Genetic Epidemiology & Clinical Research Group, Umeå University Hospital, Umeå</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A80">Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A81">Institut National de la Recherche Agronomique, Université Paris, Bobigny Cedex, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National de la Recherche Agronomique, Université Paris, Bobigny Cedex</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Frayling, Timothy M" sort="Frayling, Timothy M" uniqKey="Frayling T" first="Timothy M" last="Frayling">Timothy M. Frayling</name>
<affiliation wicri:level="1"><nlm:aff id="A30">Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Froguel, Philippe" sort="Froguel, Philippe" uniqKey="Froguel P" first="Philippe" last="Froguel">Philippe Froguel</name>
<affiliation wicri:level="1"><nlm:aff id="A9">Institut Pasteur de Lille, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A10">Lille Nord de France University, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Lille Nord de France University, Lille</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A82">Genomic Medicine, Hammersmith Hospital, Imperial College London, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Genomic Medicine, Hammersmith Hospital, Imperial College London, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Galan, Pilar" sort="Galan, Pilar" uniqKey="Galan P" first="Pilar" last="Galan">Pilar Galan</name>
<affiliation wicri:level="1"><nlm:aff id="A83">Institut National de la Santé et de la Recherche Médicale, Université Paris, Bobigny Cedex, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National de la Santé et de la Recherche Médicale, Université Paris, Bobigny Cedex</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Geus, Eco" sort="De Geus, Eco" uniqKey="De Geus E" first="Eco" last="De Geus">Eco De Geus</name>
<affiliation wicri:level="1"><nlm:aff id="A18">Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gigante, Bruna" sort="Gigante, Bruna" uniqKey="Gigante B" first="Bruna" last="Gigante">Bruna Gigante</name>
<affiliation wicri:level="1"><nlm:aff id="A68">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Glazer, Nicole L" sort="Glazer, Nicole L" uniqKey="Glazer N" first="Nicole L." last="Glazer">Nicole L. Glazer</name>
<affiliation wicri:level="1"><nlm:aff id="A84">Department of Medicine, Section of Preventive Medicine and Epidemiology, BU School of Medicine, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Section of Preventive Medicine and Epidemiology, BU School of Medicine, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A85">Department of Epidemiology, BU School of Public Health, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, BU School of Public Health, Boston, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Goel, Anuj" sort="Goel, Anuj" uniqKey="Goel A" first="Anuj" last="Goel">Anuj Goel</name>
<affiliation wicri:level="1"><nlm:aff id="A86">Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Groop, Leif" sort="Groop, Leif" uniqKey="Groop L" first="Leif" last="Groop">Leif Groop</name>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A24">Lund University Diabetes Centre, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Lund University Diabetes Centre, Malmö</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name>
<affiliation wicri:level="1"><nlm:aff id="A44">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A45">University of Iceland, Reykjavik, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>University of Iceland, Reykjavik</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hallmans, Goran" sort="Hallmans, Goran" uniqKey="Hallmans G" first="Göran" last="Hallmans">Göran Hallmans</name>
<affiliation wicri:level="1"><nlm:aff id="A87">Department of Public Health & Clinical Medicine, Nutrition Research, Umeå University, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Public Health & Clinical Medicine, Nutrition Research, Umeå University</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name>
<affiliation wicri:level="1"><nlm:aff id="A37">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hansson, Ola" sort="Hansson, Ola" uniqKey="Hansson O" first="Ola" last="Hansson">Ola Hansson</name>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A24">Lund University Diabetes Centre, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Lund University Diabetes Centre, Malmö</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B." last="Harris">Tamara B. Harris</name>
<affiliation wicri:level="1"><nlm:aff id="A88">Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name>
<affiliation wicri:level="1"><nlm:aff id="A29">MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Heath, Simon" sort="Heath, Simon" uniqKey="Heath S" first="Simon" last="Heath">Simon Heath</name>
<affiliation wicri:level="1"><nlm:aff id="A89">Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hercberg, Serge" sort="Hercberg, Serge" uniqKey="Hercberg S" first="Serge" last="Hercberg">Serge Hercberg</name>
<affiliation wicri:level="1"><nlm:aff id="A83">Institut National de la Santé et de la Recherche Médicale, Université Paris, Bobigny Cedex, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National de la Santé et de la Recherche Médicale, Université Paris, Bobigny Cedex</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hicks, Andrew A" sort="Hicks, Andrew A" uniqKey="Hicks A" first="Andrew A." last="Hicks">Andrew A. Hicks</name>
<affiliation wicri:level="1"><nlm:aff id="A90">Center for Biomedicine, European Academy Bozen/Bolzano, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Center for Biomedicine, European Academy Bozen/Bolzano, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hingorani, Aroon" sort="Hingorani, Aroon" uniqKey="Hingorani A" first="Aroon" last="Hingorani">Aroon Hingorani</name>
<affiliation wicri:level="1"><nlm:aff id="A91">Genetic epidemiology group, University College London, Department of Epidemiology & Public Health, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Genetic epidemiology group, University College London, Department of Epidemiology & Public Health, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A40">Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name>
<affiliation wicri:level="1"><nlm:aff id="A52">PathWest Laboratory Medicine of WA, J Block, QEII Medical Centre, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>PathWest Laboratory Medicine of WA, J Block, QEII Medical Centre, Nedlands</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A53">School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A54">Busselton Population Medical Research Foundation, B Block, QEII Medical Centre, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Busselton Population Medical Research Foundation, B Block, QEII Medical Centre, Nedlands</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A92">School of Population Health, The University of Western Australia, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Population Health, The University of Western Australia, Nedlands</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hung, Joseph" sort="Hung, Joseph" uniqKey="Hung J" first="Joseph" last="Hung">Joseph Hung</name>
<affiliation wicri:level="1"><nlm:aff id="A54">Busselton Population Medical Research Foundation, B Block, QEII Medical Centre, Nedlands, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Busselton Population Medical Research Foundation, B Block, QEII Medical Centre, Nedlands</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A93">Sir Charles Gairdner Hospital Unit, School of Medicine & Pharmacology, University of Western Australia, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Sir Charles Gairdner Hospital Unit, School of Medicine & Pharmacology, University of Western Australia</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jarvelin, Marjo Riitta" sort="Jarvelin, Marjo Riitta" uniqKey="Jarvelin M" first="Marjo Riitta" last="Jarvelin">Marjo Riitta Jarvelin</name>
<affiliation wicri:level="1"><nlm:aff id="A94">Department of Epidemiology and Biostatistics, School of Public Health, MRC-HPA Centre for Environment and Health, Faculty of Medicine, Imperial College London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, MRC-HPA Centre for Environment and Health, Faculty of Medicine, Imperial College London</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A95">Institute of Health Sciences, University of Oulu, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Health Sciences, University of Oulu, Oulu</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A96">Biocenter Oulu, University of Oulu, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Biocenter Oulu, University of Oulu, Oulu</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A97">National Institute of Health and Welfare, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>National Institute of Health and Welfare, Oulu</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jhun, Min A" sort="Jhun, Min A" uniqKey="Jhun M" first="Min A." last="Jhun">Min A. Jhun</name>
<affiliation wicri:level="1"><nlm:aff id="A12">Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Johnson, Paul C D" sort="Johnson, Paul C D" uniqKey="Johnson P" first="Paul C. D." last="Johnson">Paul C. D. Johnson</name>
<affiliation wicri:level="1"><nlm:aff id="A76">Robertson Centre for Biostatistics, University of Glasgow, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Robertson Centre for Biostatistics, University of Glasgow</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name>
<affiliation wicri:level="1"><nlm:aff id="A98">Department of Cardiology C5-P, Leiden University Medical Center, Leiden, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology C5-P, Leiden University Medical Center, Leiden</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A99">Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Durrer Center for Cardiogenetic Research, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jula, Antti" sort="Jula, Antti" uniqKey="Jula A" first="Antti" last="Jula">Antti Jula</name>
<affiliation wicri:level="1"><nlm:aff id="A33">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kao, W H" sort="Kao, W H" uniqKey="Kao W" first="W. H." last="Kao">W. H. Kao</name>
<affiliation wicri:level="1"><nlm:aff id="A100">Division of Epidemiology, Johns Hopkins School of Public Health, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Epidemiology, Johns Hopkins School of Public Health, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kaprio, Jaakko" sort="Kaprio, Jaakko" uniqKey="Kaprio J" first="Jaakko" last="Kaprio">Jaakko Kaprio</name>
<affiliation wicri:level="1"><nlm:aff id="A74">National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A101">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A102">Hjelt Institute, Dept of Public Health, University of Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Hjelt Institute, Dept of Public Health, University of Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kardia, Sharon L R" sort="Kardia, Sharon L R" uniqKey="Kardia S" first="Sharon L. R." last="Kardia">Sharon L. R. Kardia</name>
<affiliation wicri:level="1"><nlm:aff id="A12">Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Keinanen Kiukaanniemi, Sirkka" sort="Keinanen Kiukaanniemi, Sirkka" uniqKey="Keinanen Kiukaanniemi S" first="Sirkka" last="Keinanen-Kiukaanniemi">Sirkka Keinanen-Kiukaanniemi</name>
<affiliation wicri:level="1"><nlm:aff id="A103">Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A104">Unit of General Practice, Oulu University Hospital, Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Unit of General Practice, Oulu University Hospital, Oulu</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kivimaki, Mika" sort="Kivimaki, Mika" uniqKey="Kivimaki M" first="Mika" last="Kivimaki">Mika Kivimaki</name>
<affiliation wicri:level="1"><nlm:aff id="A62">University College London, Department of Epidemiology & Public Health, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>University College London, Department of Epidemiology & Public Health, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name>
<affiliation wicri:level="1"><nlm:aff id="A105">Department of Public Health, Faculty of Medicine, University of Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kovacs, Peter" sort="Kovacs, Peter" uniqKey="Kovacs P" first="Peter" last="Kovacs">Peter Kovacs</name>
<affiliation wicri:level="1"><nlm:aff id="A106">Interdisciplinary Centre for Clinical Research, University of Leipzig, Leipzig, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Interdisciplinary Centre for Clinical Research, University of Leipzig, Leipzig</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name>
<affiliation wicri:level="1"><nlm:aff id="A91">Genetic epidemiology group, University College London, Department of Epidemiology & Public Health, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Genetic epidemiology group, University College London, Department of Epidemiology & Public Health, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kuusisto, Johanna" sort="Kuusisto, Johanna" uniqKey="Kuusisto J" first="Johanna" last="Kuusisto">Johanna Kuusisto</name>
<affiliation wicri:level="1"><nlm:aff id="A107">Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kyvik, Kirsten Ohm" sort="Kyvik, Kirsten Ohm" uniqKey="Kyvik K" first="Kirsten Ohm" last="Kyvik">Kirsten Ohm Kyvik</name>
<affiliation><nlm:aff id="A108">Institute of Regional Health Services Research and Professor Odense Patient data Explorative Network (OPEN)</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Laakso, Markku" sort="Laakso, Markku" uniqKey="Laakso M" first="Markku" last="Laakso">Markku Laakso</name>
<affiliation wicri:level="1"><nlm:aff id="A107">Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lakka, Timo" sort="Lakka, Timo" uniqKey="Lakka T" first="Timo" last="Lakka">Timo Lakka</name>
<affiliation wicri:level="1"><nlm:aff id="A46">Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Kuopio</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A109">Kuopio Research Institute of Exercise Medicine, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Kuopio Research Institute of Exercise Medicine, Kuopio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lannfelt, Lars" sort="Lannfelt, Lars" uniqKey="Lannfelt L" first="Lars" last="Lannfelt">Lars Lannfelt</name>
<affiliation wicri:level="1"><nlm:aff id="A110">Department of Public Health and Caring Sciences, Uppsala University, Rudbecklaboratoriet, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Public Health and Caring Sciences, Uppsala University, Rudbecklaboratoriet, Uppsala</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lathrop, G Mark" sort="Lathrop, G Mark" uniqKey="Lathrop G" first="G Mark" last="Lathrop">G Mark Lathrop</name>
<affiliation wicri:level="1"><nlm:aff id="A89">Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J." last="Launer">Lenore J. Launer</name>
<affiliation wicri:level="1"><nlm:aff id="A88">Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Leander, Karin" sort="Leander, Karin" uniqKey="Leander K" first="Karin" last="Leander">Karin Leander</name>
<affiliation wicri:level="1"><nlm:aff id="A68">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, Guo" sort="Li, Guo" uniqKey="Li G" first="Guo" last="Li">Guo Li</name>
<affiliation wicri:level="1"><nlm:aff id="A111">Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name>
<affiliation wicri:level="1"><nlm:aff id="A112">Department of Medical Sciences, University Hospital, Uppsala University, Uppsala, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Sciences, University Hospital, Uppsala University, Uppsala</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lindstrom, Jaana" sort="Lindstrom, Jaana" uniqKey="Lindstrom J" first="Jaana" last="Lindstrom">Jaana Lindstrom</name>
<affiliation wicri:level="1"><nlm:aff id="A113">Diabetes Prevention Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Diabetes Prevention Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lobbens, Stephane" sort="Lobbens, Stephane" uniqKey="Lobbens S" first="Stéphane" last="Lobbens">Stéphane Lobbens</name>
<affiliation wicri:level="1"><nlm:aff id="A9">Institut Pasteur de Lille, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A10">Lille Nord de France University, Lille, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Lille Nord de France University, Lille</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J. F." last="Loos">Ruth J. F. Loos</name>
<affiliation wicri:level="1"><nlm:aff id="A7">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Luan, Jian N" sort="Luan, Jian N" uniqKey="Luan J" first="Jian N" last="Luan">Jian N Luan</name>
<affiliation wicri:level="1"><nlm:aff id="A7">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lyssenko, Valeriya" sort="Lyssenko, Valeriya" uniqKey="Lyssenko V" first="Valeriya" last="Lyssenko">Valeriya Lyssenko</name>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A24">Lund University Diabetes Centre, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Lund University Diabetes Centre, Malmö</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name>
<affiliation wicri:level="1"><nlm:aff id="A13">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A14">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A114">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff>
<country xml:lang="fr">Estonie</country>
<wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Magnusson, Patrik K E" sort="Magnusson, Patrik K E" uniqKey="Magnusson P" first="Patrik K. E." last="Magnusson">Patrik K. E. Magnusson</name>
<affiliation wicri:level="1"><nlm:aff id="A19">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Marmot, Michael" sort="Marmot, Michael" uniqKey="Marmot M" first="Michael" last="Marmot">Michael Marmot</name>
<affiliation wicri:level="1"><nlm:aff id="A62">University College London, Department of Epidemiology & Public Health, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>University College London, Department of Epidemiology & Public Health, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Meneton, Pierre" sort="Meneton, Pierre" uniqKey="Meneton P" first="Pierre" last="Meneton">Pierre Meneton</name>
<affiliation wicri:level="1"><nlm:aff id="A115">Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Paris</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mohlke, Karen L" sort="Mohlke, Karen L" uniqKey="Mohlke K" first="Karen L." last="Mohlke">Karen L. Mohlke</name>
<affiliation wicri:level="1"><nlm:aff id="A116">Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mooser, Vincent" sort="Mooser, Vincent" uniqKey="Mooser V" first="Vincent" last="Mooser">Vincent Mooser</name>
<affiliation wicri:level="1"><nlm:aff id="A117">Division of Genetics, GlaxoSmithKline, Philadelphia, Pennsylvania, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Genetics, GlaxoSmithKline, Philadelphia, Pennsylvania</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Morken, Mario A" sort="Morken, Mario A" uniqKey="Morken M" first="Mario A." last="Morken">Mario A. Morken</name>
<affiliation wicri:level="1"><nlm:aff id="A59">Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Miljkovic, Iva" sort="Miljkovic, Iva" uniqKey="Miljkovic I" first="Iva" last="Miljkovic">Iva Miljkovic</name>
<affiliation wicri:level="1"><nlm:aff id="A118">Department of Epidemiology, Center for Aging and Population Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, Center for Aging and Population Health, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Narisu, Narisu" sort="Narisu, Narisu" uniqKey="Narisu N" first="Narisu" last="Narisu">Narisu Narisu</name>
<affiliation wicri:level="1"><nlm:aff id="A59">Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="O Onnell, Jeff" sort="O Onnell, Jeff" uniqKey="O Onnell J" first="Jeff" last="O Onnell">Jeff O Onnell</name>
<affiliation wicri:level="1"><nlm:aff id="A28">Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ong, Ken K" sort="Ong, Ken K" uniqKey="Ong K" first="Ken K." last="Ong">Ken K. Ong</name>
<affiliation wicri:level="1"><nlm:aff id="A7">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A." last="Oostra">Ben A. Oostra</name>
<affiliation wicri:level="1"><nlm:aff id="A119">Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Clinical Genetics, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Palmer, Lyle J" sort="Palmer, Lyle J" uniqKey="Palmer L" first="Lyle J." last="Palmer">Lyle J. Palmer</name>
<affiliation wicri:level="1"><nlm:aff id="A16">Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research. Toronto, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research. Toronto</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A17">Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A22">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A101">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A120">Department of Medical Genetics, University of Helsinki and Helsinki University Central Hospital, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Medical Genetics, University of Helsinki and Helsinki University Central Hospital</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pankow, James S" sort="Pankow, James S" uniqKey="Pankow J" first="James S." last="Pankow">James S. Pankow</name>
<affiliation wicri:level="1"><nlm:aff id="A121">Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, Minnesota, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, Minnesota</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peden, John F" sort="Peden, John F" uniqKey="Peden J" first="John F." last="Peden">John F. Peden</name>
<affiliation wicri:level="1"><nlm:aff id="A86">Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pedersen, Nancy L" sort="Pedersen, Nancy L" uniqKey="Pedersen N" first="Nancy L." last="Pedersen">Nancy L. Pedersen</name>
<affiliation wicri:level="1"><nlm:aff id="A19">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pehlic, Marina" sort="Pehlic, Marina" uniqKey="Pehlic M" first="Marina" last="Pehlic">Marina Pehlic</name>
<affiliation wicri:level="1"><nlm:aff id="A122">Department of Biology, Faculty of Medicine, University of Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Department of Biology, Faculty of Medicine, University of Split</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peltonen, Leena" sort="Peltonen, Leena" uniqKey="Peltonen L" first="Leena" last="Peltonen">Leena Peltonen</name>
<affiliation wicri:level="1"><nlm:aff id="A22">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A101">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Penninx, Brenda" sort="Penninx, Brenda" uniqKey="Penninx B" first="Brenda" last="Penninx">Brenda Penninx</name>
<affiliation wicri:level="1"><nlm:aff id="A123">Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Psychiatry, Leiden University Medical Center, Leiden</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A124">Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A125">Department Psychiatry, EMGO Institute for Health and Care Research and Institute for Neurosciences, VU University Medical Center, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department Psychiatry, EMGO Institute for Health and Care Research and Institute for Neurosciences, VU University Medical Center, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pericic, Marijana" sort="Pericic, Marijana" uniqKey="Pericic M" first="Marijana" last="Pericic">Marijana Pericic</name>
<affiliation wicri:level="1"><nlm:aff id="A126">Institute for Anthropological Research, Zagreb, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Institute for Anthropological Research, Zagreb</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Perola, Markus" sort="Perola, Markus" uniqKey="Perola M" first="Markus" last="Perola">Markus Perola</name>
<affiliation wicri:level="1"><nlm:aff id="A33">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Perusse, Louis" sort="Perusse, Louis" uniqKey="Perusse L" first="Louis" last="Perusse">Louis Perusse</name>
<affiliation wicri:level="1"><nlm:aff id="A127">Department of Preventive Medicine, Laval University, Quebec, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Preventive Medicine, Laval University, Quebec</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peyser, Patricia A" sort="Peyser, Patricia A" uniqKey="Peyser P" first="Patricia A" last="Peyser">Patricia A. Peyser</name>
<affiliation wicri:level="1"><nlm:aff id="A12">Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name>
<affiliation wicri:level="1"><nlm:aff id="A105">Department of Public Health, Faculty of Medicine, University of Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Department of Public Health, Faculty of Medicine, University of Split</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pramstaller, Peter P" sort="Pramstaller, Peter P" uniqKey="Pramstaller P" first="Peter P." last="Pramstaller">Peter P. Pramstaller</name>
<affiliation wicri:level="1"><nlm:aff id="A90">Center for Biomedicine, European Academy Bozen/Bolzano, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Center for Biomedicine, European Academy Bozen/Bolzano, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Province, Michael A" sort="Province, Michael A" uniqKey="Province M" first="Michael A." last="Province">Michael A. Province</name>
<affiliation wicri:level="1"><nlm:aff id="A41">Department of Genetics Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Genetics Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="R Ikkonen, Katri" sort="R Ikkonen, Katri" uniqKey="R Ikkonen K" first="Katri" last="R Ikkönen">Katri R Ikkönen</name>
<affiliation wicri:level="1"><nlm:aff id="A25">Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rauramaa, Rainer" sort="Rauramaa, Rainer" uniqKey="Rauramaa R" first="Rainer" last="Rauramaa">Rainer Rauramaa</name>
<affiliation wicri:level="1"><nlm:aff id="A109">Kuopio Research Institute of Exercise Medicine, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Kuopio Research Institute of Exercise Medicine, Kuopio</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A128">Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rehnberg, Emil" sort="Rehnberg, Emil" uniqKey="Rehnberg E" first="Emil" last="Rehnberg">Emil Rehnberg</name>
<affiliation wicri:level="1"><nlm:aff id="A19">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rice, Ken" sort="Rice, Ken" uniqKey="Rice K" first="Ken" last="Rice">Ken Rice</name>
<affiliation wicri:level="1"><nlm:aff id="A129">Department of Biostatistics, University of Washington, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biostatistics, University of Washington, Seattle, Washington</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I." last="Rotter">Jerome I. Rotter</name>
<affiliation><nlm:aff id="A130">Medical Genetics Institute, Cedars-Sinai Medical Center</nlm:aff>
<wicri:noCountry code="subfield">Cedars-Sinai Medical Center</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name>
<affiliation wicri:level="1"><nlm:aff id="A63">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A131">Centre for Global Health, University of Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Centre for Global Health, University of Split</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ruokonen, Aimo" sort="Ruokonen, Aimo" uniqKey="Ruokonen A" first="Aimo" last="Ruokonen">Aimo Ruokonen</name>
<affiliation wicri:level="1"><nlm:aff id="A132">Institute of Clinical Medicine, University of Oulu, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Clinical Medicine, University of Oulu</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Saaristo, Timo" sort="Saaristo, Timo" uniqKey="Saaristo T" first="Timo" last="Saaristo">Timo Saaristo</name>
<affiliation wicri:level="1"><nlm:aff id="A133">Finnish Diabetes Association, Tampere, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Finnish Diabetes Association, Tampere</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A134">Pirkanmaa Hospital District, Tampere, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Pirkanmaa Hospital District, Tampere</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sabater Lleal, Maria" sort="Sabater Lleal, Maria" uniqKey="Sabater Lleal M" first="Maria" last="Sabater-Lleal">Maria Sabater-Lleal</name>
<affiliation wicri:level="1"><nlm:aff id="A37">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name>
<affiliation wicri:level="1"><nlm:aff id="A33">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Savage, David B" sort="Savage, David B" uniqKey="Savage D" first="David B." last="Savage">David B. Savage</name>
<affiliation wicri:level="1"><nlm:aff id="A135">Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Saxena, Richa" sort="Saxena, Richa" uniqKey="Saxena R" first="Richa" last="Saxena">Richa Saxena</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A136">Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schwarz, Peter" sort="Schwarz, Peter" uniqKey="Schwarz P" first="Peter" last="Schwarz">Peter Schwarz</name>
<affiliation wicri:level="1"><nlm:aff id="A137">Department of Medicine, Division Prevention and Care of Diabetes, University of Dresden, Dresden, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Medicine, Division Prevention and Care of Diabetes, University of Dresden, Dresden</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Seedorf, Udo" sort="Seedorf, Udo" uniqKey="Seedorf U" first="Udo" last="Seedorf">Udo Seedorf</name>
<affiliation wicri:level="1"><nlm:aff id="A138">Leibniz Institute for Arteriosclerosis Research, University of Munster, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Leibniz Institute for Arteriosclerosis Research, University of Munster</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sennblad, Bengt" sort="Sennblad, Bengt" uniqKey="Sennblad B" first="Bengt" last="Sennblad">Bengt Sennblad</name>
<affiliation wicri:level="1"><nlm:aff id="A37">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Serrano Rios, Manuel" sort="Serrano Rios, Manuel" uniqKey="Serrano Rios M" first="Manuel" last="Serrano-Rios">Manuel Serrano-Rios</name>
<affiliation wicri:level="1"><nlm:aff id="A27">Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R." last="Shuldiner">Alan R. Shuldiner</name>
<affiliation wicri:level="1"><nlm:aff id="A28">Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A139">Geriatric Research and Education Clinical Center, Veterans Administration Medical Center, Baltimore, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Geriatric Research and Education Clinical Center, Veterans Administration Medical Center, Baltimore, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sijbrands, Eric J G" sort="Sijbrands, Eric J G" uniqKey="Sijbrands E" first="Eric J. G." last="Sijbrands">Eric J. G. Sijbrands</name>
<affiliation wicri:level="1"><nlm:aff id="A140">Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Internal Medicine, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Siscovick, David S" sort="Siscovick, David S" uniqKey="Siscovick D" first="David S." last="Siscovick">David S. Siscovick</name>
<affiliation wicri:level="1"><nlm:aff id="A111">Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cardiovascular Health Research Unit, University of Washington, Seattle, Washington</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A141">Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A142">Department of Epidemiology, University of Washington, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Smit, Johannes H" sort="Smit, Johannes H" uniqKey="Smit J" first="Johannes H." last="Smit">Johannes H. Smit</name>
<affiliation wicri:level="1"><nlm:aff id="A143">Department of Psychiatry, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Psychiatry, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Small, Kerrin S" sort="Small, Kerrin S" uniqKey="Small K" first="Kerrin S." last="Small">Kerrin S. Small</name>
<affiliation wicri:level="1"><nlm:aff id="A31">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Smith, Nicholas L" sort="Smith, Nicholas L" uniqKey="Smith N" first="Nicholas L." last="Smith">Nicholas L. Smith</name>
<affiliation wicri:level="1"><nlm:aff id="A141">Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A142">Department of Epidemiology, University of Washington, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A144">Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Group Health Research Institute, Group Health Cooperative, Seattle, Washington</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A145">Seattle Epidemiologic Research and Information Center, Veterans Affairs Office of Research and Development, Seattle, WA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Seattle Epidemiologic Research and Information Center, Veterans Affairs Office of Research and Development, Seattle, WA</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Smith, Albert Vernon" sort="Smith, Albert Vernon" uniqKey="Smith A" first="Albert Vernon" last="Smith">Albert Vernon Smith</name>
<affiliation wicri:level="1"><nlm:aff id="A44">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A45">University of Iceland, Reykjavik, Iceland</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>University of Iceland, Reykjavik</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stan Kova, Alena" sort="Stan Kova, Alena" uniqKey="Stan Kova A" first="Alena" last="Stan Ková">Alena Stan Ková</name>
<affiliation wicri:level="1"><nlm:aff id="A107">Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stirrups, Kathleen" sort="Stirrups, Kathleen" uniqKey="Stirrups K" first="Kathleen" last="Stirrups">Kathleen Stirrups</name>
<affiliation wicri:level="1"><nlm:aff id="A22">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stumvoll, Michael" sort="Stumvoll, Michael" uniqKey="Stumvoll M" first="Michael" last="Stumvoll">Michael Stumvoll</name>
<affiliation wicri:level="1"><nlm:aff id="A60">IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>IFB Adiposity Diseases, University of Leipzig, Leipzig</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A146">Department of Medicine, University of Leipzig, Division of Endocrinology and Diabetes, Leipzig, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Medicine, University of Leipzig, Division of Endocrinology and Diabetes, Leipzig</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sun, Yan V" sort="Sun, Yan V" uniqKey="Sun Y" first="Yan V." last="Sun">Yan V. Sun</name>
<affiliation wicri:level="1"><nlm:aff id="A147">Department of Epidemiology, Emory University, Atlanta, Georgia, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, Emory University, Atlanta, Georgia</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Swift, Amy J" sort="Swift, Amy J" uniqKey="Swift A" first="Amy J." last="Swift">Amy J. Swift</name>
<affiliation wicri:level="1"><nlm:aff id="A59">Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tonjes, Anke" sort="Tonjes, Anke" uniqKey="Tonjes A" first="Anke" last="Tönjes">Anke Tönjes</name>
<affiliation wicri:level="1"><nlm:aff id="A60">IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>IFB Adiposity Diseases, University of Leipzig, Leipzig</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A146">Department of Medicine, University of Leipzig, Division of Endocrinology and Diabetes, Leipzig, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Medicine, University of Leipzig, Division of Endocrinology and Diabetes, Leipzig</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name>
<affiliation wicri:level="1"><nlm:aff id="A148">Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A149">South Ostrobothnia Central Hospital, Seinäjoki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>South Ostrobothnia Central Hospital, Seinäjoki</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A150">Hospital Universitario La Paz, Madrid, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Hospital Universitario La Paz, Madrid</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A151">Centre for Vascular Prevention, Danube-University Krems, Krems, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Centre for Vascular Prevention, Danube-University Krems, Krems</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name>
<affiliation wicri:level="1"><nlm:aff id="A98">Department of Cardiology C5-P, Leiden University Medical Center, Leiden, the Netherlands</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology C5-P, Leiden University Medical Center, Leiden</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="Andre G." last="Uitterlinden">Andre G. Uitterlinden</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A40">Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A140">Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Internal Medicine, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Uusitupa, Matti" sort="Uusitupa, Matti" uniqKey="Uusitupa M" first="Matti" last="Uusitupa">Matti Uusitupa</name>
<affiliation wicri:level="1"><nlm:aff id="A152">Institute of Public Health and Clinical Nutrition, University of Easten Finland, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Public Health and Clinical Nutrition, University of Easten Finland, Kuopio</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A153">Research Unit, Kuopio University Hospital, Kuopio, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Research Unit, Kuopio University Hospital, Kuopio</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Vikstrom, Max" sort="Vikstrom, Max" uniqKey="Vikstrom M" first="Max" last="Vikström">Max Vikström</name>
<affiliation wicri:level="1"><nlm:aff id="A68">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name>
<affiliation wicri:level="1"><nlm:aff id="A29">MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Vohl, Marie Claude" sort="Vohl, Marie Claude" uniqKey="Vohl M" first="Marie-Claude" last="Vohl">Marie-Claude Vohl</name>
<affiliation wicri:level="1"><nlm:aff id="A154">Department of Food Science and Nutrition, Laval University, Quebec, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Food Science and Nutrition, Laval University, Quebec</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Voight, Benjamin F" sort="Voight, Benjamin F" uniqKey="Voight B" first="Benjamin F." last="Voight">Benjamin F. Voight</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Vollenweider, Peter" sort="Vollenweider, Peter" uniqKey="Vollenweider P" first="Peter" last="Vollenweider">Peter Vollenweider</name>
<affiliation wicri:level="1"><nlm:aff id="A155">Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Waeber, Gerard" sort="Waeber, Gerard" uniqKey="Waeber G" first="Gerard" last="Waeber">Gerard Waeber</name>
<affiliation wicri:level="1"><nlm:aff id="A155">Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Waterworth, Dawn M" sort="Waterworth, Dawn M" uniqKey="Waterworth D" first="Dawn M" last="Waterworth">Dawn M. Waterworth</name>
<affiliation wicri:level="1"><nlm:aff id="A117">Division of Genetics, GlaxoSmithKline, Philadelphia, Pennsylvania, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Genetics, GlaxoSmithKline, Philadelphia, Pennsylvania</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Watkins, Hugh" sort="Watkins, Hugh" uniqKey="Watkins H" first="Hugh" last="Watkins">Hugh Watkins</name>
<affiliation wicri:level="1"><nlm:aff id="A86">Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wheeler, Eleanor" sort="Wheeler, Eleanor" uniqKey="Wheeler E" first="Eleanor" last="Wheeler">Eleanor Wheeler</name>
<affiliation wicri:level="1"><nlm:aff id="A156">Metabolic Disease Group, Wellcome Trust Sanger Institute, Hinxton, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Metabolic Disease Group, Wellcome Trust Sanger Institute, Hinxton</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Widen, Elisabeth" sort="Widen, Elisabeth" uniqKey="Widen E" first="Elisabeth" last="Widen">Elisabeth Widen</name>
<affiliation wicri:level="1"><nlm:aff id="A157">Institute for Molecular Medicine Finland, University of Helsinki, Finland</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wild, Sarah H" sort="Wild, Sarah H" uniqKey="Wild S" first="Sarah H." last="Wild">Sarah H. Wild</name>
<affiliation wicri:level="1"><nlm:aff id="A63">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Willems, Sara M" sort="Willems, Sara M" uniqKey="Willems S" first="Sara M." last="Willems">Sara M. Willems</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name>
<affiliation wicri:level="1"><nlm:aff id="A18">Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F." last="Wilson">James F. Wilson</name>
<affiliation wicri:level="1"><nlm:aff id="A63">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Witteman, Jacqueline C M" sort="Witteman, Jacqueline C M" uniqKey="Witteman J" first="Jacqueline C. M." last="Witteman">Jacqueline C. M. Witteman</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A40">Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F." last="Wright">Alan F. Wright</name>
<affiliation wicri:level="1"><nlm:aff id="A29">MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yaghootkar, Hanieh" sort="Yaghootkar, Hanieh" uniqKey="Yaghootkar H" first="Hanieh" last="Yaghootkar">Hanieh Yaghootkar</name>
<affiliation wicri:level="1"><nlm:aff id="A30">Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zelenika, Diana" sort="Zelenika, Diana" uniqKey="Zelenika D" first="Diana" last="Zelenika">Diana Zelenika</name>
<affiliation wicri:level="1"><nlm:aff id="A89">Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zemunik, Tatijana" sort="Zemunik, Tatijana" uniqKey="Zemunik T" first="Tatijana" last="Zemunik">Tatijana Zemunik</name>
<affiliation wicri:level="1"><nlm:aff id="A122">Department of Biology, Faculty of Medicine, University of Split, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Department of Biology, Faculty of Medicine, University of Split</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zgaga, Lina" sort="Zgaga, Lina" uniqKey="Zgaga L" first="Lina" last="Zgaga">Lina Zgaga</name>
<affiliation wicri:level="1"><nlm:aff id="A63">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A158">Department of medical statistics, epidemiology and medical informatics, University of Zagreb, Zagreb, Croatia</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Department of medical statistics, epidemiology and medical informatics, University of Zagreb, Zagreb</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J." last="Wareham">Nicholas J. Wareham</name>
<affiliation wicri:level="1"><nlm:aff id="A7">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I." last="Mccarthy">Mark I. Mccarthy</name>
<affiliation wicri:level="1"><nlm:aff id="A13">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A14">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A159">Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Ines" last="Barroso">Ines Barroso</name>
<affiliation wicri:level="1"><nlm:aff id="A156">Metabolic Disease Group, Wellcome Trust Sanger Institute, Hinxton, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Metabolic Disease Group, Wellcome Trust Sanger Institute, Hinxton</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A160">University of Cambridge, Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>University of Cambridge, Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Watanabe, Richard M" sort="Watanabe, Richard M" uniqKey="Watanabe R" first="Richard M." last="Watanabe">Richard M. Watanabe</name>
<affiliation wicri:level="1"><nlm:aff id="A56">Department of Physiology & Biophysics, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Physiology & Biophysics, Keck School of Medicine of the University of Southern California, Los Angeles, California</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A161">Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Florez, Jose C" sort="Florez, Jose C" uniqKey="Florez J" first="Jose C." last="Florez">Jose C. Florez</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A8">Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Harvard Medical School, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A136">Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A162">Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dupuis, Josee" sort="Dupuis, Josee" uniqKey="Dupuis J" first="Josée" last="Dupuis">Josée Dupuis</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A77">National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Meigs, James B" sort="Meigs, James B" uniqKey="Meigs J" first="James B." last="Meigs">James B. Meigs</name>
<affiliation wicri:level="1"><nlm:aff id="A5">General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A8">Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Harvard Medical School, Boston, Massachusetts</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name>
<affiliation wicri:level="1"><nlm:aff id="A7">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Nature genetics</title>
<idno type="ISSN">1061-4036</idno>
<idno type="eISSN">1546-1718</idno>
<imprint><date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
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</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">Recent genome-wide association studies have described many loci implicated in type 2 diabetes (T2D) pathophysiology and beta-cell dysfunction, but contributed little to our understanding of the genetic basis of insulin resistance. We hypothesized that genes implicated in insulin resistance pathways may be uncovered by accounting for differences in body mass index (BMI) and potential interaction between BMI and genetic variants. We applied a novel joint meta-analytical approach to test associations with fasting insulin (FI) and glucose (FG) on a genome-wide scale. We present six previously unknown FI loci at <italic>P</italic>
<5×10<sup>−8</sup>
in combined discovery and follow-up analyses of 52 studies comprising up to 96,496non-diabetic individuals. Risk variants were associated with higher triglyceride and lower HDL cholesterol levels, suggestive of a role for these FI loci in insulin resistance pathways. The localization of these additional loci will aid further characterization of the role of insulin resistance in T2D pathophysiology.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9216904</journal-id>
<journal-id journal-id-type="pubmed-jr-id">2419</journal-id>
<journal-id journal-id-type="nlm-ta">Nat Genet</journal-id>
<journal-id journal-id-type="iso-abbrev">Nat. Genet.</journal-id>
<journal-title-group><journal-title>Nature genetics</journal-title>
</journal-title-group>
<issn pub-type="ppub">1061-4036</issn>
<issn pub-type="epub">1546-1718</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">22581228</article-id>
<article-id pub-id-type="pmc">3613127</article-id>
<article-id pub-id-type="doi">10.1038/ng.2274</article-id>
<article-id pub-id-type="manuscript">NIHMS430753</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance</article-title>
</title-group>
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<given-names>Timothy M</given-names>
</name>
<xref ref-type="aff" rid="A30">30</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Froguel</surname>
<given-names>Philippe</given-names>
</name>
<xref ref-type="aff" rid="A9">9</xref>
<xref ref-type="aff" rid="A10">10</xref>
<xref ref-type="aff" rid="A82">82</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Galan</surname>
<given-names>Pilar</given-names>
</name>
<xref ref-type="aff" rid="A83">83</xref>
</contrib>
<contrib contrib-type="author"><name><surname>de Geus</surname>
<given-names>Eco</given-names>
</name>
<xref ref-type="aff" rid="A18">18</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gigante</surname>
<given-names>Bruna</given-names>
</name>
<xref ref-type="aff" rid="A68">68</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Glazer</surname>
<given-names>Nicole L.</given-names>
</name>
<xref ref-type="aff" rid="A84">84</xref>
<xref ref-type="aff" rid="A85">85</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Goel</surname>
<given-names>Anuj</given-names>
</name>
<xref ref-type="aff" rid="A86">86</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Groop</surname>
<given-names>Leif</given-names>
</name>
<xref ref-type="aff" rid="A23">23</xref>
<xref ref-type="aff" rid="A24">24</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gudnason</surname>
<given-names>Vilmundur</given-names>
</name>
<xref ref-type="aff" rid="A44">44</xref>
<xref ref-type="aff" rid="A45">45</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hallmans</surname>
<given-names>Göran</given-names>
</name>
<xref ref-type="aff" rid="A87">87</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hamsten</surname>
<given-names>Anders</given-names>
</name>
<xref ref-type="aff" rid="A37">37</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hansson</surname>
<given-names>Ola</given-names>
</name>
<xref ref-type="aff" rid="A23">23</xref>
<xref ref-type="aff" rid="A24">24</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Harris</surname>
<given-names>Tamara B.</given-names>
</name>
<xref ref-type="aff" rid="A88">88</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hayward</surname>
<given-names>Caroline</given-names>
</name>
<xref ref-type="aff" rid="A29">29</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Heath</surname>
<given-names>Simon</given-names>
</name>
<xref ref-type="aff" rid="A89">89</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hercberg</surname>
<given-names>Serge</given-names>
</name>
<xref ref-type="aff" rid="A83">83</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hicks</surname>
<given-names>Andrew A.</given-names>
</name>
<xref ref-type="aff" rid="A90">90</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hingorani</surname>
<given-names>Aroon</given-names>
</name>
<xref ref-type="aff" rid="A91">91</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hofman</surname>
<given-names>Albert</given-names>
</name>
<xref ref-type="aff" rid="A15">15</xref>
<xref ref-type="aff" rid="A40">40</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hui</surname>
<given-names>Jennie</given-names>
</name>
<xref ref-type="aff" rid="A52">52</xref>
<xref ref-type="aff" rid="A53">53</xref>
<xref ref-type="aff" rid="A54">54</xref>
<xref ref-type="aff" rid="A92">92</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hung</surname>
<given-names>Joseph</given-names>
</name>
<xref ref-type="aff" rid="A54">54</xref>
<xref ref-type="aff" rid="A93">93</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jarvelin</surname>
<given-names>Marjo Riitta</given-names>
</name>
<xref ref-type="aff" rid="A94">94</xref>
<xref ref-type="aff" rid="A95">95</xref>
<xref ref-type="aff" rid="A96">96</xref>
<xref ref-type="aff" rid="A97">97</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jhun</surname>
<given-names>Min A.</given-names>
</name>
<xref ref-type="aff" rid="A12">12</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Johnson</surname>
<given-names>Paul C.D.</given-names>
</name>
<xref ref-type="aff" rid="A76">76</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jukema</surname>
<given-names>J Wouter</given-names>
</name>
<xref ref-type="aff" rid="A98">98</xref>
<xref ref-type="aff" rid="A99">99</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jula</surname>
<given-names>Antti</given-names>
</name>
<xref ref-type="aff" rid="A33">33</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kao</surname>
<given-names>W.H.</given-names>
</name>
<xref ref-type="aff" rid="A100">100</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kaprio</surname>
<given-names>Jaakko</given-names>
</name>
<xref ref-type="aff" rid="A74">74</xref>
<xref ref-type="aff" rid="A101">101</xref>
<xref ref-type="aff" rid="A102">102</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kardia</surname>
<given-names>Sharon L. R.</given-names>
</name>
<xref ref-type="aff" rid="A12">12</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Keinanen-Kiukaanniemi</surname>
<given-names>Sirkka</given-names>
</name>
<xref ref-type="aff" rid="A103">103</xref>
<xref ref-type="aff" rid="A104">104</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kivimaki</surname>
<given-names>Mika</given-names>
</name>
<xref ref-type="aff" rid="A62">62</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kolcic</surname>
<given-names>Ivana</given-names>
</name>
<xref ref-type="aff" rid="A105">105</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kovacs</surname>
<given-names>Peter</given-names>
</name>
<xref ref-type="aff" rid="A106">106</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kumari</surname>
<given-names>Meena</given-names>
</name>
<xref ref-type="aff" rid="A91">91</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kuusisto</surname>
<given-names>Johanna</given-names>
</name>
<xref ref-type="aff" rid="A107">107</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kyvik</surname>
<given-names>Kirsten Ohm</given-names>
</name>
<xref ref-type="aff" rid="A108">108</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Laakso</surname>
<given-names>Markku</given-names>
</name>
<xref ref-type="aff" rid="A107">107</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lakka</surname>
<given-names>Timo</given-names>
</name>
<xref ref-type="aff" rid="A46">46</xref>
<xref ref-type="aff" rid="A109">109</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lannfelt</surname>
<given-names>Lars</given-names>
</name>
<xref ref-type="aff" rid="A110">110</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lathrop</surname>
<given-names>G Mark</given-names>
</name>
<xref ref-type="aff" rid="A89">89</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Launer</surname>
<given-names>Lenore J.</given-names>
</name>
<xref ref-type="aff" rid="A88">88</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Leander</surname>
<given-names>Karin</given-names>
</name>
<xref ref-type="aff" rid="A68">68</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Li</surname>
<given-names>Guo</given-names>
</name>
<xref ref-type="aff" rid="A111">111</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lind</surname>
<given-names>Lars</given-names>
</name>
<xref ref-type="aff" rid="A112">112</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lindstrom</surname>
<given-names>Jaana</given-names>
</name>
<xref ref-type="aff" rid="A113">113</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lobbens</surname>
<given-names>Stéphane</given-names>
</name>
<xref ref-type="aff" rid="A9">9</xref>
<xref ref-type="aff" rid="A10">10</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Loos</surname>
<given-names>Ruth J. F.</given-names>
</name>
<xref ref-type="aff" rid="A7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Luan</surname>
<given-names>Jian’an</given-names>
</name>
<xref ref-type="aff" rid="A7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lyssenko</surname>
<given-names>Valeriya</given-names>
</name>
<xref ref-type="aff" rid="A23">23</xref>
<xref ref-type="aff" rid="A24">24</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mägi</surname>
<given-names>Reedik</given-names>
</name>
<xref ref-type="aff" rid="A13">13</xref>
<xref ref-type="aff" rid="A14">14</xref>
<xref ref-type="aff" rid="A114">114</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Magnusson</surname>
<given-names>Patrik K. E.</given-names>
</name>
<xref ref-type="aff" rid="A19">19</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Marmot</surname>
<given-names>Michael</given-names>
</name>
<xref ref-type="aff" rid="A62">62</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Meneton</surname>
<given-names>Pierre</given-names>
</name>
<xref ref-type="aff" rid="A115">115</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mohlke</surname>
<given-names>Karen L.</given-names>
</name>
<xref ref-type="aff" rid="A116">116</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mooser</surname>
<given-names>Vincent</given-names>
</name>
<xref ref-type="aff" rid="A117">117</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Morken</surname>
<given-names>Mario A.</given-names>
</name>
<xref ref-type="aff" rid="A59">59</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Miljkovic</surname>
<given-names>Iva</given-names>
</name>
<xref ref-type="aff" rid="A118">118</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Narisu</surname>
<given-names>Narisu</given-names>
</name>
<xref ref-type="aff" rid="A59">59</xref>
</contrib>
<contrib contrib-type="author"><name><surname>O’Connell</surname>
<given-names>Jeff</given-names>
</name>
<xref ref-type="aff" rid="A28">28</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ong</surname>
<given-names>Ken K.</given-names>
</name>
<xref ref-type="aff" rid="A7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Oostra</surname>
<given-names>Ben A.</given-names>
</name>
<xref ref-type="aff" rid="A119">119</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Palmer</surname>
<given-names>Lyle J.</given-names>
</name>
<xref ref-type="aff" rid="A16">16</xref>
<xref ref-type="aff" rid="A17">17</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Palotie</surname>
<given-names>Aarno</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
<xref ref-type="aff" rid="A22">22</xref>
<xref ref-type="aff" rid="A101">101</xref>
<xref ref-type="aff" rid="A120">120</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pankow</surname>
<given-names>James S.</given-names>
</name>
<xref ref-type="aff" rid="A121">121</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Peden</surname>
<given-names>John F.</given-names>
</name>
<xref ref-type="aff" rid="A86">86</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pedersen</surname>
<given-names>Nancy L.</given-names>
</name>
<xref ref-type="aff" rid="A19">19</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pehlic</surname>
<given-names>Marina</given-names>
</name>
<xref ref-type="aff" rid="A122">122</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Peltonen</surname>
<given-names>Leena</given-names>
</name>
<xref ref-type="aff" rid="A22">22</xref>
<xref ref-type="aff" rid="A101">101</xref>
<xref rid="FN5" ref-type="author-notes">**</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Penninx</surname>
<given-names>Brenda</given-names>
</name>
<xref ref-type="aff" rid="A123">123</xref>
<xref ref-type="aff" rid="A124">124</xref>
<xref ref-type="aff" rid="A125">125</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pericic</surname>
<given-names>Marijana</given-names>
</name>
<xref ref-type="aff" rid="A126">126</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Perola</surname>
<given-names>Markus</given-names>
</name>
<xref ref-type="aff" rid="A33">33</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Perusse</surname>
<given-names>Louis</given-names>
</name>
<xref ref-type="aff" rid="A127">127</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Peyser</surname>
<given-names>Patricia A</given-names>
</name>
<xref ref-type="aff" rid="A12">12</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Polasek</surname>
<given-names>Ozren</given-names>
</name>
<xref ref-type="aff" rid="A105">105</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pramstaller</surname>
<given-names>Peter P.</given-names>
</name>
<xref ref-type="aff" rid="A90">90</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Province</surname>
<given-names>Michael A.</given-names>
</name>
<xref ref-type="aff" rid="A41">41</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Räikkönen</surname>
<given-names>Katri</given-names>
</name>
<xref ref-type="aff" rid="A25">25</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rauramaa</surname>
<given-names>Rainer</given-names>
</name>
<xref ref-type="aff" rid="A109">109</xref>
<xref ref-type="aff" rid="A128">128</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rehnberg</surname>
<given-names>Emil</given-names>
</name>
<xref ref-type="aff" rid="A19">19</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rice</surname>
<given-names>Ken</given-names>
</name>
<xref ref-type="aff" rid="A129">129</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rotter</surname>
<given-names>Jerome I.</given-names>
</name>
<xref ref-type="aff" rid="A130">130</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Rudan</surname>
<given-names>Igor</given-names>
</name>
<xref ref-type="aff" rid="A63">63</xref>
<xref ref-type="aff" rid="A131">131</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ruokonen</surname>
<given-names>Aimo</given-names>
</name>
<xref ref-type="aff" rid="A132">132</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Saaristo</surname>
<given-names>Timo</given-names>
</name>
<xref ref-type="aff" rid="A133">133</xref>
<xref ref-type="aff" rid="A134">134</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sabater-Lleal</surname>
<given-names>Maria</given-names>
</name>
<xref ref-type="aff" rid="A37">37</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Salomaa</surname>
<given-names>Veikko</given-names>
</name>
<xref ref-type="aff" rid="A33">33</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Savage</surname>
<given-names>David B.</given-names>
</name>
<xref ref-type="aff" rid="A135">135</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Saxena</surname>
<given-names>Richa</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
<xref ref-type="aff" rid="A136">136</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Schwarz</surname>
<given-names>Peter</given-names>
</name>
<xref ref-type="aff" rid="A137">137</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Seedorf</surname>
<given-names>Udo</given-names>
</name>
<xref ref-type="aff" rid="A138">138</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sennblad</surname>
<given-names>Bengt</given-names>
</name>
<xref ref-type="aff" rid="A37">37</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Serrano-Rios</surname>
<given-names>Manuel</given-names>
</name>
<xref ref-type="aff" rid="A27">27</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Shuldiner</surname>
<given-names>Alan R.</given-names>
</name>
<xref ref-type="aff" rid="A28">28</xref>
<xref ref-type="aff" rid="A139">139</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sijbrands</surname>
<given-names>Eric J.G.</given-names>
</name>
<xref ref-type="aff" rid="A140">140</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Siscovick</surname>
<given-names>David S.</given-names>
</name>
<xref ref-type="aff" rid="A111">111</xref>
<xref ref-type="aff" rid="A141">141</xref>
<xref ref-type="aff" rid="A142">142</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Smit</surname>
<given-names>Johannes H.</given-names>
</name>
<xref ref-type="aff" rid="A143">143</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Small</surname>
<given-names>Kerrin S.</given-names>
</name>
<xref ref-type="aff" rid="A31">31</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Smith</surname>
<given-names>Nicholas L.</given-names>
</name>
<xref ref-type="aff" rid="A141">141</xref>
<xref ref-type="aff" rid="A142">142</xref>
<xref ref-type="aff" rid="A144">144</xref>
<xref ref-type="aff" rid="A145">145</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Smith</surname>
<given-names>Albert Vernon</given-names>
</name>
<xref ref-type="aff" rid="A44">44</xref>
<xref ref-type="aff" rid="A45">45</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Stančáková</surname>
<given-names>Alena</given-names>
</name>
<xref ref-type="aff" rid="A107">107</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Stirrups</surname>
<given-names>Kathleen</given-names>
</name>
<xref ref-type="aff" rid="A22">22</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Stumvoll</surname>
<given-names>Michael</given-names>
</name>
<xref ref-type="aff" rid="A60">60</xref>
<xref ref-type="aff" rid="A146">146</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Sun</surname>
<given-names>Yan V.</given-names>
</name>
<xref ref-type="aff" rid="A147">147</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Swift</surname>
<given-names>Amy J.</given-names>
</name>
<xref ref-type="aff" rid="A59">59</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Tönjes</surname>
<given-names>Anke</given-names>
</name>
<xref ref-type="aff" rid="A60">60</xref>
<xref ref-type="aff" rid="A146">146</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Tuomilehto</surname>
<given-names>Jaakko</given-names>
</name>
<xref ref-type="aff" rid="A148">148</xref>
<xref ref-type="aff" rid="A149">149</xref>
<xref ref-type="aff" rid="A150">150</xref>
<xref ref-type="aff" rid="A151">151</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Trompet</surname>
<given-names>Stella</given-names>
</name>
<xref ref-type="aff" rid="A98">98</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Uitterlinden</surname>
<given-names>Andre G.</given-names>
</name>
<xref ref-type="aff" rid="A15">15</xref>
<xref ref-type="aff" rid="A40">40</xref>
<xref ref-type="aff" rid="A140">140</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Uusitupa</surname>
<given-names>Matti</given-names>
</name>
<xref ref-type="aff" rid="A152">152</xref>
<xref ref-type="aff" rid="A153">153</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Vikström</surname>
<given-names>Max</given-names>
</name>
<xref ref-type="aff" rid="A68">68</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Vitart</surname>
<given-names>Veronique</given-names>
</name>
<xref ref-type="aff" rid="A29">29</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Vohl</surname>
<given-names>Marie-Claude</given-names>
</name>
<xref ref-type="aff" rid="A154">154</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Voight</surname>
<given-names>Benjamin F.</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Vollenweider</surname>
<given-names>Peter</given-names>
</name>
<xref ref-type="aff" rid="A155">155</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Waeber</surname>
<given-names>Gerard</given-names>
</name>
<xref ref-type="aff" rid="A155">155</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Waterworth</surname>
<given-names>Dawn M</given-names>
</name>
<xref ref-type="aff" rid="A117">117</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Watkins</surname>
<given-names>Hugh</given-names>
</name>
<xref ref-type="aff" rid="A86">86</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wheeler</surname>
<given-names>Eleanor</given-names>
</name>
<xref ref-type="aff" rid="A156">156</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Widen</surname>
<given-names>Elisabeth</given-names>
</name>
<xref ref-type="aff" rid="A157">157</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wild</surname>
<given-names>Sarah H.</given-names>
</name>
<xref ref-type="aff" rid="A63">63</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Willems</surname>
<given-names>Sara M.</given-names>
</name>
<xref ref-type="aff" rid="A15">15</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Willemsen</surname>
<given-names>Gonneke</given-names>
</name>
<xref ref-type="aff" rid="A18">18</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wilson</surname>
<given-names>James F.</given-names>
</name>
<xref ref-type="aff" rid="A63">63</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Witteman</surname>
<given-names>Jacqueline C.M.</given-names>
</name>
<xref ref-type="aff" rid="A15">15</xref>
<xref ref-type="aff" rid="A40">40</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wright</surname>
<given-names>Alan F.</given-names>
</name>
<xref ref-type="aff" rid="A29">29</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Yaghootkar</surname>
<given-names>Hanieh</given-names>
</name>
<xref ref-type="aff" rid="A30">30</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Zelenika</surname>
<given-names>Diana</given-names>
</name>
<xref ref-type="aff" rid="A89">89</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Zemunik</surname>
<given-names>Tatijana</given-names>
</name>
<xref ref-type="aff" rid="A122">122</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Zgaga</surname>
<given-names>Lina</given-names>
</name>
<xref ref-type="aff" rid="A63">63</xref>
<xref ref-type="aff" rid="A158">158</xref>
</contrib>
<contrib contrib-type="author"><collab>DIAGRAM Consortium</collab>
<xref rid="FN2" ref-type="author-notes">159</xref>
</contrib>
<contrib contrib-type="author"><collab>The MUTHER Consortium</collab>
<xref rid="FN2" ref-type="author-notes">159</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wareham</surname>
<given-names>Nicholas J.</given-names>
</name>
<xref ref-type="aff" rid="A7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>McCarthy</surname>
<given-names>Mark I.</given-names>
</name>
<xref ref-type="aff" rid="A13">13</xref>
<xref ref-type="aff" rid="A14">14</xref>
<xref ref-type="aff" rid="A159">160</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Barroso</surname>
<given-names>Ines</given-names>
</name>
<xref ref-type="aff" rid="A156">156</xref>
<xref ref-type="aff" rid="A160">161</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Watanabe</surname>
<given-names>Richard M.</given-names>
</name>
<xref ref-type="aff" rid="A56">56</xref>
<xref ref-type="aff" rid="A161">162</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Florez</surname>
<given-names>Jose C.</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
<xref ref-type="aff" rid="A8">8</xref>
<xref ref-type="aff" rid="A136">136</xref>
<xref ref-type="aff" rid="A162">163</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dupuis</surname>
<given-names>Josée</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
<xref ref-type="aff" rid="A77">77</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Meigs</surname>
<given-names>James B.</given-names>
</name>
<xref ref-type="aff" rid="A5">5</xref>
<xref ref-type="aff" rid="A8">8</xref>
<xref rid="FN1" ref-type="author-notes">†</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Langenberg</surname>
<given-names>Claudia</given-names>
</name>
<xref ref-type="aff" rid="A7">7</xref>
<xref rid="FN1" ref-type="author-notes">†</xref>
</contrib>
</contrib-group>
<aff id="A1"><label>1</label>
Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA</aff>
<aff id="A2"><label>2</label>
Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA</aff>
<aff id="A3"><label>3</label>
Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA</aff>
<aff id="A4"><label>4</label>
Harvard Medical School, Boston, Massachusetts</aff>
<aff id="A5"><label>5</label>
General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts, USA</aff>
<aff id="A6"><label>6</label>
Department of Medicine, Universite de Sherbrooke, Sherbrooke, Québec, Canada</aff>
<aff id="A7"><label>7</label>
MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</aff>
<aff id="A8"><label>8</label>
Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA</aff>
<aff id="A9"><label>9</label>
Institut Pasteur de Lille, Lille, France</aff>
<aff id="A10"><label>10</label>
Lille Nord de France University, Lille, France</aff>
<aff id="A11"><label>11</label>
Boston University Data Coordinating Center, Boston, Massachusetts, USA</aff>
<aff id="A12"><label>12</label>
Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA</aff>
<aff id="A13"><label>13</label>
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK</aff>
<aff id="A14"><label>14</label>
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</aff>
<aff id="A15"><label>15</label>
Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</aff>
<aff id="A16"><label>16</label>
Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research. Toronto, Canada</aff>
<aff id="A17"><label>17</label>
Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Canada</aff>
<aff id="A18"><label>18</label>
Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</aff>
<aff id="A19"><label>19</label>
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden</aff>
<aff id="A20"><label>20</label>
Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA</aff>
<aff id="A21"><label>21</label>
Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK</aff>
<aff id="A22"><label>22</label>
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hixton, Cambridge, UK</aff>
<aff id="A23"><label>23</label>
Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, Malmö, Sweden</aff>
<aff id="A24"><label>24</label>
Lund University Diabetes Centre, Malmö, Sweden</aff>
<aff id="A25"><label>25</label>
Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland</aff>
<aff id="A26"><label>26</label>
Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA</aff>
<aff id="A27"><label>27</label>
Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain</aff>
<aff id="A28"><label>28</label>
Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland, USA</aff>
<aff id="A29"><label>29</label>
MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Edinburgh, UK</aff>
<aff id="A30"><label>30</label>
Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK</aff>
<aff id="A31"><label>31</label>
Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</aff>
<aff id="A32"><label>32</label>
Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA</aff>
<aff id="A33"><label>33</label>
Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</aff>
<aff id="A34"><label>34</label>
Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK</aff>
<aff id="A35"><label>35</label>
Department of Public Health & Clinical Medicine, Genetic Epidemiology & Clinical Research Group, Umeå University Hospital, Umeå, Sweden</aff>
<aff id="A36"><label>36</label>
Department of Odontology, Umeå University, Sweden</aff>
<aff id="A37"><label>37</label>
Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden</aff>
<aff id="A38"><label>38</label>
Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, USA</aff>
<aff id="A39"><label>39</label>
Centre for medical systems biology, Netherlands Genomics Initiative, The Hague</aff>
<aff id="A40"><label>40</label>
Netherlands Genomics Initiative and the Netherlands Consortium for Healthy Aging, Rotterdam, The Netherlands</aff>
<aff id="A41"><label>41</label>
Department of Genetics Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, USA</aff>
<aff id="A42"><label>42</label>
Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA</aff>
<aff id="A43"><label>43</label>
Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA</aff>
<aff id="A44"><label>44</label>
Icelandic Heart Association, Kopavogur, Iceland</aff>
<aff id="A45"><label>45</label>
University of Iceland, Reykjavik, Iceland</aff>
<aff id="A46"><label>46</label>
Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Kuopio, Finland</aff>
<aff id="A47"><label>47</label>
Inserm, CESP Centre for research in Epidemiology and Population Health, Villejuif, France</aff>
<aff id="A48"><label>48</label>
University Paris Sud 11, Villejuif, France</aff>
<aff id="A49"><label>49</label>
Geriatric Unit, Azienda Sanitaria di Firenze, Florence, Italy</aff>
<aff id="A50"><label>50</label>
Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland</aff>
<aff id="A51"><label>51</label>
Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland</aff>
<aff id="A52"><label>52</label>
PathWest Laboratory Medicine of WA, J Block, QEII Medical Centre, Nedlands, Australia</aff>
<aff id="A53"><label>53</label>
School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, Australia</aff>
<aff id="A54"><label>54</label>
Busselton Population Medical Research Foundation, B Block, QEII Medical Centre, Nedlands, Australia</aff>
<aff id="A55"><label>55</label>
Texas Biomedical Research Institute, San Antonio, Texas, USA</aff>
<aff id="A56"><label>56</label>
Department of Physiology & Biophysics, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA</aff>
<aff id="A57"><label>57</label>
Department of Pharmacology, Faculty of Medicine, University of Split, Croatia</aff>
<aff id="A58"><label>58</label>
Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA</aff>
<aff id="A59"><label>59</label>
Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA</aff>
<aff id="A60"><label>60</label>
IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany</aff>
<aff id="A61"><label>61</label>
Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA</aff>
<aff id="A62"><label>62</label>
University College London, Department of Epidemiology & Public Health, London, UK</aff>
<aff id="A63"><label>63</label>
Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</aff>
<aff id="A64"><label>64</label>
Laboratory of Clinical Investigation, National Institute of Aging, Baltimore, Maryland, USA</aff>
<aff id="A65"><label>65</label>
Clinical Trial Service Unit, University of Oxford, Oxford, UK</aff>
<aff id="A66"><label>66</label>
Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA</aff>
<aff id="A67"><label>67</label>
Department of Biostatistics, University of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina, USA</aff>
<aff id="A68"><label>68</label>
Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</aff>
<aff id="A69"><label>69</label>
Department of Nutrition - Dietetics, Harokopio University, Athens, Greece</aff>
<aff id="A70"><label>70</label>
Department of General Practice and Primary health Care, University of Helsinki, Finland</aff>
<aff id="A71"><label>71</label>
Helsinki University Central Hospital, Unit of General Practice, Helsinki, Finland</aff>
<aff id="A72"><label>72</label>
Folkhalsan Research Centre, Helsinki, Finland</aff>
<aff id="A73"><label>73</label>
Vaasa Central Hospital, Vaasa, Finland</aff>
<aff id="A74"><label>74</label>
National Institute for Health and Welfare, Helsinki, Finland</aff>
<aff id="A75"><label>75</label>
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, USA</aff>
<aff id="A76"><label>76</label>
Robertson Centre for Biostatistics, University of Glasgow, UK</aff>
<aff id="A77"><label>77</label>
National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA</aff>
<aff id="A78"><label>78</label>
Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA</aff>
<aff id="A79"><label>79</label>
Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research, Milan, Italy</aff>
<aff id="A80"><label>80</label>
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA</aff>
<aff id="A81"><label>81</label>
Institut National de la Recherche Agronomique, Université Paris, Bobigny Cedex, France</aff>
<aff id="A82"><label>82</label>
Genomic Medicine, Hammersmith Hospital, Imperial College London, London, UK</aff>
<aff id="A83"><label>83</label>
Institut National de la Santé et de la Recherche Médicale, Université Paris, Bobigny Cedex, France</aff>
<aff id="A84"><label>84</label>
Department of Medicine, Section of Preventive Medicine and Epidemiology, BU School of Medicine, Boston, Massachusetts, USA</aff>
<aff id="A85"><label>85</label>
Department of Epidemiology, BU School of Public Health, Boston, Massachusetts, USA</aff>
<aff id="A86"><label>86</label>
Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</aff>
<aff id="A87"><label>87</label>
Department of Public Health & Clinical Medicine, Nutrition Research, Umeå University, Sweden</aff>
<aff id="A88"><label>88</label>
Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland, USA</aff>
<aff id="A89"><label>89</label>
Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry, France</aff>
<aff id="A90"><label>90</label>
Center for Biomedicine, European Academy Bozen/Bolzano, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany</aff>
<aff id="A91"><label>91</label>
Genetic epidemiology group, University College London, Department of Epidemiology & Public Health, London, UK</aff>
<aff id="A92"><label>92</label>
School of Population Health, The University of Western Australia, Nedlands, Australia</aff>
<aff id="A93"><label>93</label>
Sir Charles Gairdner Hospital Unit, School of Medicine & Pharmacology, University of Western Australia, Australia</aff>
<aff id="A94"><label>94</label>
Department of Epidemiology and Biostatistics, School of Public Health, MRC-HPA Centre for Environment and Health, Faculty of Medicine, Imperial College London, UK</aff>
<aff id="A95"><label>95</label>
Institute of Health Sciences, University of Oulu, Oulu, Finland</aff>
<aff id="A96"><label>96</label>
Biocenter Oulu, University of Oulu, Oulu, Finland</aff>
<aff id="A97"><label>97</label>
National Institute of Health and Welfare, Oulu, Finland</aff>
<aff id="A98"><label>98</label>
Department of Cardiology C5-P, Leiden University Medical Center, Leiden, the Netherlands</aff>
<aff id="A99"><label>99</label>
Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands</aff>
<aff id="A100"><label>100</label>
Division of Epidemiology, Johns Hopkins School of Public Health, Baltimore, Maryland, USA</aff>
<aff id="A101"><label>101</label>
Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</aff>
<aff id="A102"><label>102</label>
Hjelt Institute, Dept of Public Health, University of Helsinki, Finland</aff>
<aff id="A103"><label>103</label>
Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland</aff>
<aff id="A104"><label>104</label>
Unit of General Practice, Oulu University Hospital, Oulu, Finland</aff>
<aff id="A105"><label>105</label>
Department of Public Health, Faculty of Medicine, University of Split, Croatia</aff>
<aff id="A106"><label>106</label>
Interdisciplinary Centre for Clinical Research, University of Leipzig, Leipzig, Germany</aff>
<aff id="A107"><label>107</label>
Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland</aff>
<aff id="A108"><label>108</label>
Institute of Regional Health Services Research and Professor Odense Patient data Explorative Network (OPEN)</aff>
<aff id="A109"><label>109</label>
Kuopio Research Institute of Exercise Medicine, Kuopio, Finland</aff>
<aff id="A110"><label>110</label>
Department of Public Health and Caring Sciences, Uppsala University, Rudbecklaboratoriet, Uppsala, Sweden</aff>
<aff id="A111"><label>111</label>
Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA</aff>
<aff id="A112"><label>112</label>
Department of Medical Sciences, University Hospital, Uppsala University, Uppsala, Sweden</aff>
<aff id="A113"><label>113</label>
Diabetes Prevention Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</aff>
<aff id="A114"><label>114</label>
Estonian Genome Center, University of Tartu, Tartu, Estonia</aff>
<aff id="A115"><label>115</label>
Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Paris, France</aff>
<aff id="A116"><label>116</label>
Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA</aff>
<aff id="A117"><label>117</label>
Division of Genetics, GlaxoSmithKline, Philadelphia, Pennsylvania, USA</aff>
<aff id="A118"><label>118</label>
Department of Epidemiology, Center for Aging and Population Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA</aff>
<aff id="A119"><label>119</label>
Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands</aff>
<aff id="A120"><label>120</label>
Department of Medical Genetics, University of Helsinki and Helsinki University Central Hospital, Finland</aff>
<aff id="A121"><label>121</label>
Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, Minnesota, USA</aff>
<aff id="A122"><label>122</label>
Department of Biology, Faculty of Medicine, University of Split, Croatia</aff>
<aff id="A123"><label>123</label>
Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands</aff>
<aff id="A124"><label>124</label>
Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</aff>
<aff id="A125"><label>125</label>
Department Psychiatry, EMGO Institute for Health and Care Research and Institute for Neurosciences, VU University Medical Center, Amsterdam, The Netherlands</aff>
<aff id="A126"><label>126</label>
Institute for Anthropological Research, Zagreb, Croatia</aff>
<aff id="A127"><label>127</label>
Department of Preventive Medicine, Laval University, Quebec, Canada</aff>
<aff id="A128"><label>128</label>
Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland</aff>
<aff id="A129"><label>129</label>
Department of Biostatistics, University of Washington, Seattle, Washington, USA</aff>
<aff id="A130"><label>130</label>
Medical Genetics Institute, Cedars-Sinai Medical Center</aff>
<aff id="A131"><label>131</label>
Centre for Global Health, University of Split, Croatia</aff>
<aff id="A132"><label>132</label>
Institute of Clinical Medicine, University of Oulu, Finland</aff>
<aff id="A133"><label>133</label>
Finnish Diabetes Association, Tampere, Finland</aff>
<aff id="A134"><label>134</label>
Pirkanmaa Hospital District, Tampere, Finland</aff>
<aff id="A135"><label>135</label>
Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK</aff>
<aff id="A136"><label>136</label>
Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA</aff>
<aff id="A137"><label>137</label>
Department of Medicine, Division Prevention and Care of Diabetes, University of Dresden, Dresden, Germany</aff>
<aff id="A138"><label>138</label>
Leibniz Institute for Arteriosclerosis Research, University of Munster, Germany</aff>
<aff id="A139"><label>139</label>
Geriatric Research and Education Clinical Center, Veterans Administration Medical Center, Baltimore, Maryland, USA</aff>
<aff id="A140"><label>140</label>
Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands</aff>
<aff id="A141"><label>141</label>
Department of Medicine, University of Washington, Seattle, Washington, USA</aff>
<aff id="A142"><label>142</label>
Department of Epidemiology, University of Washington, Seattle, Washington, USA</aff>
<aff id="A143"><label>143</label>
Department of Psychiatry, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands</aff>
<aff id="A144"><label>144</label>
Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA</aff>
<aff id="A145"><label>145</label>
Seattle Epidemiologic Research and Information Center, Veterans Affairs Office of Research and Development, Seattle, WA, USA</aff>
<aff id="A146"><label>146</label>
Department of Medicine, University of Leipzig, Division of Endocrinology and Diabetes, Leipzig, Germany</aff>
<aff id="A147"><label>147</label>
Department of Epidemiology, Emory University, Atlanta, Georgia, US</aff>
<aff id="A148"><label>148</label>
Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland</aff>
<aff id="A149"><label>149</label>
South Ostrobothnia Central Hospital, Seinäjoki, Finland</aff>
<aff id="A150"><label>150</label>
Hospital Universitario La Paz, Madrid, Spain</aff>
<aff id="A151"><label>151</label>
Centre for Vascular Prevention, Danube-University Krems, Krems, Austria</aff>
<aff id="A152"><label>152</label>
Institute of Public Health and Clinical Nutrition, University of Easten Finland, Kuopio, Finland</aff>
<aff id="A153"><label>153</label>
Research Unit, Kuopio University Hospital, Kuopio, Finland</aff>
<aff id="A154"><label>154</label>
Department of Food Science and Nutrition, Laval University, Quebec, Canada</aff>
<aff id="A155"><label>155</label>
Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland</aff>
<aff id="A156"><label>156</label>
Metabolic Disease Group, Wellcome Trust Sanger Institute, Hinxton, UK</aff>
<aff id="A157"><label>157</label>
Institute for Molecular Medicine Finland, University of Helsinki, Finland</aff>
<aff id="A158"><label>158</label>
Department of medical statistics, epidemiology and medical informatics, University of Zagreb, Zagreb, Croatia</aff>
<aff id="A159"><label>160</label>
Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, UK</aff>
<aff id="A160"><label>161</label>
University of Cambridge, Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</aff>
<aff id="A161"><label>162</label>
Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA</aff>
<aff id="A162"><label>163</label>
Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA</aff>
<author-notes><corresp id="FN1"><label>†</label>
Co-corresponding Authors: James B. Meigs, Harvard Medical School, General Medicine Division, Massachusetts General Hospital, 50 Staniford St 9th Floor, Boston MA 02114, Tel. 617-724-3203, Fax. 617-724-3544, <email>jmeigs@partners.org</email>
, Claudia Langenberg, MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge CB2 0QQ, United Kingdom, Tel. +44 (0)1223 769137, Fax. +44 (0)1223 330316, <email>Claudia.Langenberg@mrc-epid.cam.ac.uk</email>
</corresp>
<fn id="FN2"><label>159</label>
<p>A full list of members is provided in the <xref rid="SD1" ref-type="supplementary-material">Supplementary Note</xref>
</p>
</fn>
<fn id="FN3" fn-type="equal"><label>*</label>
<p>These authors contributed equally to this work</p>
</fn>
<fn id="FN4"><label>†</label>
<p>These authors jointly directed the work</p>
</fn>
<fn id="FN5"><label>**</label>
<p>Deceased</p>
</fn>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>4</day>
<month>1</month>
<year>2013</year>
</pub-date>
<pub-date pub-type="epub"><day>13</day>
<month>5</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>01</day>
<month>4</month>
<year>2013</year>
</pub-date>
<volume>44</volume>
<issue>6</issue>
<fpage>659</fpage>
<lpage>669</lpage>
<abstract><p id="P1">Recent genome-wide association studies have described many loci implicated in type 2 diabetes (T2D) pathophysiology and beta-cell dysfunction, but contributed little to our understanding of the genetic basis of insulin resistance. We hypothesized that genes implicated in insulin resistance pathways may be uncovered by accounting for differences in body mass index (BMI) and potential interaction between BMI and genetic variants. We applied a novel joint meta-analytical approach to test associations with fasting insulin (FI) and glucose (FG) on a genome-wide scale. We present six previously unknown FI loci at <italic>P</italic>
<5×10<sup>−8</sup>
in combined discovery and follow-up analyses of 52 studies comprising up to 96,496non-diabetic individuals. Risk variants were associated with higher triglyceride and lower HDL cholesterol levels, suggestive of a role for these FI loci in insulin resistance pathways. The localization of these additional loci will aid further characterization of the role of insulin resistance in T2D pathophysiology.</p>
</abstract>
<funding-group><award-group><funding-source country="United States">National Institute of Diabetes and Digestive and Kidney Diseases : NIDDK</funding-source>
<award-id>R01 DK078616 || DK</award-id>
</award-group>
</funding-group>
</article-meta>
</front>
</pmc>
</record>
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