Exposure to substances in the workplace and new-onset asthma : an international prospective population-based study (ECRHS-II). Commentary
Identifieur interne : 002605 ( PascalFrancis/Curation ); précédent : 002604; suivant : 002606Exposure to substances in the workplace and new-onset asthma : an international prospective population-based study (ECRHS-II). Commentary
Auteurs : Jean-Luc Malo [Canada] ; Denyse Gautrin [Canada] ; Manolis Kogevinas [Espagne, Grèce] ; Jan-Paul Zock [Espagne] ; Debbie Jarvis [Royaume-Uni] ; Hans Kromhout [Pays-Bas] ; Linnéa Lillienberg [Suède] ; Estel Plana [Espagne] ; Katja Radon [Allemagne] ; Kjell Taren [Suède] ; Ada Alliksoo [Estonie] ; Geza Benke [Australie] ; Paul D. Blanc [États-Unis] ; Anna Dahlman-Hoglund [Suède] ; Angelo D'Errico [Italie] ; Michel Hery [France] ; Susan Kennedy [Canada] ; Nino Kunzli [Espagne] ; Bénédicte Leynaert [France] ; Maria C. Mirabelli [Espagne] ; Nerea Muniozguren [Espagne] ; Dan Norback ; Mario Olivieri ; Félix Payo ; Simona Villani ; Marc Van Sprundel ; Isabel Urrutia ; Gunilla Wieslander ; Jordi Sunyer [Espagne] ; Josep M. Anto [Espagne]Source :
- Lancet : (British edition) [ 0140-6736 ] ; 2007.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Santé publique, Prospective, Médecine.
English descriptors
- KwdEn :
Abstract
Background The role of exposure to substances in the workplace in new-onset asthma is not well characterised in population-based studies. We therefore aimed to estimate the relative and attributable risks of new-onset asthma in relation to occupations, work-related exposures, and inhalation accidents. Methods We studied prospectively 6837 participants from 13 countries who previously took part in the European Community Respiratory Health Survey (1990-95) and did not report respiratory symptoms or a history of asthma at the time of the first study. Asthma was assessed by methacholine challenge test and by questionnaire data on asthma symptoms. Exposures were defined by high-risk occupations, an asthma-specific job exposure matrix with additional expert judgment, and through self-report of acute inhalation events. Relative risks for new onset asthma were calculated with log-binomial models adjusted for age, sex, smoking, and study centre. Findings A significant excess asthma risk was seen after exposure to substances known to cause occupational asthma (Relative risk=1.6, 95% CI 1.1-2.3, p=0.017). Risks were highest for asthma defined by bronchial hyper-reactivity in addition to symptoms (2.4, 1.3-4.6, p=0.008). Of common occupations, a significant excess risk of asthma was seen for nursing (2.2, 1.3-4.0, p=0.007). Asthma risk was also increased in participants who reported an acute symptomatic inhalation event such as fire, mixing cleaning products, or chemical spills (RR=3.3, 95% CI 1.0-11.1, p=0.051). The population-attributable risk for adult asthma due to occupational exposures ranged from 10% to 25%, equivalent to an incidence of new-onset occupational asthma of 250-300 cases per million people per year. Interpretation Occupational exposures account for a substantial proportion of adult asthma incidence. The increased risk of asthma after inhalation accidents suggests that workers who have such accidents should be monitored closely.
pA |
|
---|
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :003A83
Links to Exploration step
Pascal:07-0364785Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Exposure to substances in the workplace and new-onset asthma : an international prospective population-based study (ECRHS-II). Commentary</title>
<author><name sortKey="Malo, Jean Luc" sort="Malo, Jean Luc" uniqKey="Malo J" first="Jean-Luc" last="Malo">Jean-Luc Malo</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Axe de recherche en santé respiratoire and Center for Asthma in the Workplace, Department of Chest Medicine, Sacré-Coeur Hospital</s1>
<s2>Montreal, H4J 1C5</s2>
<s3>CAN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Canada</country>
</affiliation>
</author>
<author><name sortKey="Gautrin, Denyse" sort="Gautrin, Denyse" uniqKey="Gautrin D" first="Denyse" last="Gautrin">Denyse Gautrin</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Axe de recherche en santé respiratoire and Center for Asthma in the Workplace, Department of Chest Medicine, Sacré-Coeur Hospital</s1>
<s2>Montreal, H4J 1C5</s2>
<s3>CAN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Canada</country>
</affiliation>
</author>
<author><name sortKey="Kogevinas, Manolis" sort="Kogevinas, Manolis" uniqKey="Kogevinas M" first="Manolis" last="Kogevinas">Manolis Kogevinas</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Medical School, University of Crete</s1>
<s2>Heraklion</s2>
<s3>GRC</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Grèce</country>
</affiliation>
</author>
<author><name sortKey="Zock, Jan Paul" sort="Zock, Jan Paul" uniqKey="Zock J" first="Jan-Paul" last="Zock">Jan-Paul Zock</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
</author>
<author><name sortKey="Jarvis, Debbie" sort="Jarvis, Debbie" uniqKey="Jarvis D" first="Debbie" last="Jarvis">Debbie Jarvis</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Respiratory Epidemiology and Public Health Group, National Heart and Lung Institute, Imperial College</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
</affiliation>
</author>
<author><name sortKey="Kromhout, Hans" sort="Kromhout, Hans" uniqKey="Kromhout H" first="Hans" last="Kromhout">Hans Kromhout</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Division of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University</s1>
<s2>Utrecht</s2>
<s3>NLD</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
</affiliation>
</author>
<author><name sortKey="Lillienberg, Linnea" sort="Lillienberg, Linnea" uniqKey="Lillienberg L" first="Linnéa" last="Lillienberg">Linnéa Lillienberg</name>
<affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital</s1>
<s2>Goteborg</s2>
<s3>SWE</s3>
<sZ>7 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
</author>
<author><name sortKey="Plana, Estel" sort="Plana, Estel" uniqKey="Plana E" first="Estel" last="Plana">Estel Plana</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
</author>
<author><name sortKey="Radon, Katja" sort="Radon, Katja" uniqKey="Radon K" first="Katja" last="Radon">Katja Radon</name>
<affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Unit for Occupational and Environmental Epidemiology and NetTeaching, Institute for Occupational and Environmental Medicine, Ludwig-Maximilians-University</s1>
<s2>Munich</s2>
<s3>DEU</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Taren, Kjell" sort="Taren, Kjell" uniqKey="Taren K" first="Kjell" last="Taren">Kjell Taren</name>
<affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital</s1>
<s2>Goteborg</s2>
<s3>SWE</s3>
<sZ>7 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
</author>
<author><name sortKey="Alliksoo, Ada" sort="Alliksoo, Ada" uniqKey="Alliksoo A" first="Ada" last="Alliksoo">Ada Alliksoo</name>
<affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Tartu University Clinics, Lung Clinic</s1>
<s2>Tartu</s2>
<s3>EST</s3>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>Estonie</country>
</affiliation>
</author>
<author><name sortKey="Benke, Geza" sort="Benke, Geza" uniqKey="Benke G" first="Geza" last="Benke">Geza Benke</name>
<affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Department of Epidemiology and Preventive Medicine, Monash University</s1>
<s2>VIC</s2>
<s3>AUS</s3>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>Australie</country>
</affiliation>
</author>
<author><name sortKey="Blanc, Paul D" sort="Blanc, Paul D" uniqKey="Blanc P" first="Paul D." last="Blanc">Paul D. Blanc</name>
<affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Division of Occupational and Environmental Medicine, Department of Medicine, University of California San Francisco</s1>
<s2>San Francisco, CA</s2>
<s3>USA</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Dahlman Hoglund, Anna" sort="Dahlman Hoglund, Anna" uniqKey="Dahlman Hoglund A" first="Anna" last="Dahlman-Hoglund">Anna Dahlman-Hoglund</name>
<affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital</s1>
<s2>Goteborg</s2>
<s3>SWE</s3>
<sZ>7 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
</author>
<author><name sortKey="D Errico, Angelo" sort="D Errico, Angelo" uniqKey="D Errico A" first="Angelo" last="D'Errico">Angelo D'Errico</name>
<affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Servizio Regionale di Epidemiologia</s1>
<s2>Turin</s2>
<s3>ITA</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="Hery, Michel" sort="Hery, Michel" uniqKey="Hery M" first="Michel" last="Hery">Michel Hery</name>
<affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Institut National de Recherche et de Sécurité</s1>
<s2>Vandoeuvre -lès -Nancy</s2>
<s3>FRA</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Kennedy, Susan" sort="Kennedy, Susan" uniqKey="Kennedy S" first="Susan" last="Kennedy">Susan Kennedy</name>
<affiliation wicri:level="1"><inist:fA14 i1="13"><s1>School of Occupational and Environmental Hygiene, University of British Columbia</s1>
<s2>Vancouver, BC</s2>
<s3>CAN</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>Canada</country>
</affiliation>
</author>
<author><name sortKey="Kunzli, Nino" sort="Kunzli, Nino" uniqKey="Kunzli N" first="Nino" last="Kunzli">Nino Kunzli</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
</author>
<author><name sortKey="Leynaert, Benedicte" sort="Leynaert, Benedicte" uniqKey="Leynaert B" first="Bénédicte" last="Leynaert">Bénédicte Leynaert</name>
<affiliation wicri:level="1"><inist:fA14 i1="14"><s1>INSERM-The French Institute of Health and Medical Research, Unit 700-Epidemiology, Faculty of Medicine X Bichat</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Mirabelli, Maria C" sort="Mirabelli, Maria C" uniqKey="Mirabelli M" first="Maria C." last="Mirabelli">Maria C. Mirabelli</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
</author>
<author><name sortKey="Muniozguren, Nerea" sort="Muniozguren, Nerea" uniqKey="Muniozguren N" first="Nerea" last="Muniozguren">Nerea Muniozguren</name>
<affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Epidemiology Unit, Public Health Department of Bizkaia</s1>
<s2>Galolatao</s2>
<s3>ESP</s3>
<sZ>21 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
</author>
<author><name sortKey="Norback, Dan" sort="Norback, Dan" uniqKey="Norback D" first="Dan" last="Norback">Dan Norback</name>
</author>
<author><name sortKey="Olivieri, Mario" sort="Olivieri, Mario" uniqKey="Olivieri M" first="Mario" last="Olivieri">Mario Olivieri</name>
</author>
<author><name sortKey="Payo, Felix" sort="Payo, Felix" uniqKey="Payo F" first="Félix" last="Payo">Félix Payo</name>
</author>
<author><name sortKey="Villani, Simona" sort="Villani, Simona" uniqKey="Villani S" first="Simona" last="Villani">Simona Villani</name>
</author>
<author><name sortKey="Van Sprundel, Marc" sort="Van Sprundel, Marc" uniqKey="Van Sprundel M" first="Marc" last="Van Sprundel">Marc Van Sprundel</name>
</author>
<author><name sortKey="Urrutia, Isabel" sort="Urrutia, Isabel" uniqKey="Urrutia I" first="Isabel" last="Urrutia">Isabel Urrutia</name>
</author>
<author><name sortKey="Wieslander, Gunilla" sort="Wieslander, Gunilla" uniqKey="Wieslander G" first="Gunilla" last="Wieslander">Gunilla Wieslander</name>
</author>
<author><name sortKey="Sunyer, Jordi" sort="Sunyer, Jordi" uniqKey="Sunyer J" first="Jordi" last="Sunyer">Jordi Sunyer</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
</author>
<author><name sortKey="Anto, Josep M" sort="Anto, Josep M" uniqKey="Anto J" first="Josep M." last="Anto">Josep M. Anto</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">07-0364785</idno>
<date when="2007">2007</date>
<idno type="stanalyst">PASCAL 07-0364785 INIST</idno>
<idno type="RBID">Pascal:07-0364785</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">003A83</idno>
<idno type="wicri:Area/PascalFrancis/Curation">002605</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Exposure to substances in the workplace and new-onset asthma : an international prospective population-based study (ECRHS-II). Commentary</title>
<author><name sortKey="Malo, Jean Luc" sort="Malo, Jean Luc" uniqKey="Malo J" first="Jean-Luc" last="Malo">Jean-Luc Malo</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Axe de recherche en santé respiratoire and Center for Asthma in the Workplace, Department of Chest Medicine, Sacré-Coeur Hospital</s1>
<s2>Montreal, H4J 1C5</s2>
<s3>CAN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Canada</country>
</affiliation>
</author>
<author><name sortKey="Gautrin, Denyse" sort="Gautrin, Denyse" uniqKey="Gautrin D" first="Denyse" last="Gautrin">Denyse Gautrin</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Axe de recherche en santé respiratoire and Center for Asthma in the Workplace, Department of Chest Medicine, Sacré-Coeur Hospital</s1>
<s2>Montreal, H4J 1C5</s2>
<s3>CAN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Canada</country>
</affiliation>
</author>
<author><name sortKey="Kogevinas, Manolis" sort="Kogevinas, Manolis" uniqKey="Kogevinas M" first="Manolis" last="Kogevinas">Manolis Kogevinas</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Medical School, University of Crete</s1>
<s2>Heraklion</s2>
<s3>GRC</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Grèce</country>
</affiliation>
</author>
<author><name sortKey="Zock, Jan Paul" sort="Zock, Jan Paul" uniqKey="Zock J" first="Jan-Paul" last="Zock">Jan-Paul Zock</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
</author>
<author><name sortKey="Jarvis, Debbie" sort="Jarvis, Debbie" uniqKey="Jarvis D" first="Debbie" last="Jarvis">Debbie Jarvis</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Respiratory Epidemiology and Public Health Group, National Heart and Lung Institute, Imperial College</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
</affiliation>
</author>
<author><name sortKey="Kromhout, Hans" sort="Kromhout, Hans" uniqKey="Kromhout H" first="Hans" last="Kromhout">Hans Kromhout</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Division of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University</s1>
<s2>Utrecht</s2>
<s3>NLD</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
</affiliation>
</author>
<author><name sortKey="Lillienberg, Linnea" sort="Lillienberg, Linnea" uniqKey="Lillienberg L" first="Linnéa" last="Lillienberg">Linnéa Lillienberg</name>
<affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital</s1>
<s2>Goteborg</s2>
<s3>SWE</s3>
<sZ>7 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
</author>
<author><name sortKey="Plana, Estel" sort="Plana, Estel" uniqKey="Plana E" first="Estel" last="Plana">Estel Plana</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
</author>
<author><name sortKey="Radon, Katja" sort="Radon, Katja" uniqKey="Radon K" first="Katja" last="Radon">Katja Radon</name>
<affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Unit for Occupational and Environmental Epidemiology and NetTeaching, Institute for Occupational and Environmental Medicine, Ludwig-Maximilians-University</s1>
<s2>Munich</s2>
<s3>DEU</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
</affiliation>
</author>
<author><name sortKey="Taren, Kjell" sort="Taren, Kjell" uniqKey="Taren K" first="Kjell" last="Taren">Kjell Taren</name>
<affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital</s1>
<s2>Goteborg</s2>
<s3>SWE</s3>
<sZ>7 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
</author>
<author><name sortKey="Alliksoo, Ada" sort="Alliksoo, Ada" uniqKey="Alliksoo A" first="Ada" last="Alliksoo">Ada Alliksoo</name>
<affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Tartu University Clinics, Lung Clinic</s1>
<s2>Tartu</s2>
<s3>EST</s3>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>Estonie</country>
</affiliation>
</author>
<author><name sortKey="Benke, Geza" sort="Benke, Geza" uniqKey="Benke G" first="Geza" last="Benke">Geza Benke</name>
<affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Department of Epidemiology and Preventive Medicine, Monash University</s1>
<s2>VIC</s2>
<s3>AUS</s3>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>Australie</country>
</affiliation>
</author>
<author><name sortKey="Blanc, Paul D" sort="Blanc, Paul D" uniqKey="Blanc P" first="Paul D." last="Blanc">Paul D. Blanc</name>
<affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Division of Occupational and Environmental Medicine, Department of Medicine, University of California San Francisco</s1>
<s2>San Francisco, CA</s2>
<s3>USA</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
</affiliation>
</author>
<author><name sortKey="Dahlman Hoglund, Anna" sort="Dahlman Hoglund, Anna" uniqKey="Dahlman Hoglund A" first="Anna" last="Dahlman-Hoglund">Anna Dahlman-Hoglund</name>
<affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital</s1>
<s2>Goteborg</s2>
<s3>SWE</s3>
<sZ>7 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Suède</country>
</affiliation>
</author>
<author><name sortKey="D Errico, Angelo" sort="D Errico, Angelo" uniqKey="D Errico A" first="Angelo" last="D'Errico">Angelo D'Errico</name>
<affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Servizio Regionale di Epidemiologia</s1>
<s2>Turin</s2>
<s3>ITA</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>Italie</country>
</affiliation>
</author>
<author><name sortKey="Hery, Michel" sort="Hery, Michel" uniqKey="Hery M" first="Michel" last="Hery">Michel Hery</name>
<affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Institut National de Recherche et de Sécurité</s1>
<s2>Vandoeuvre -lès -Nancy</s2>
<s3>FRA</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Kennedy, Susan" sort="Kennedy, Susan" uniqKey="Kennedy S" first="Susan" last="Kennedy">Susan Kennedy</name>
<affiliation wicri:level="1"><inist:fA14 i1="13"><s1>School of Occupational and Environmental Hygiene, University of British Columbia</s1>
<s2>Vancouver, BC</s2>
<s3>CAN</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>Canada</country>
</affiliation>
</author>
<author><name sortKey="Kunzli, Nino" sort="Kunzli, Nino" uniqKey="Kunzli N" first="Nino" last="Kunzli">Nino Kunzli</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
</author>
<author><name sortKey="Leynaert, Benedicte" sort="Leynaert, Benedicte" uniqKey="Leynaert B" first="Bénédicte" last="Leynaert">Bénédicte Leynaert</name>
<affiliation wicri:level="1"><inist:fA14 i1="14"><s1>INSERM-The French Institute of Health and Medical Research, Unit 700-Epidemiology, Faculty of Medicine X Bichat</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Mirabelli, Maria C" sort="Mirabelli, Maria C" uniqKey="Mirabelli M" first="Maria C." last="Mirabelli">Maria C. Mirabelli</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
</author>
<author><name sortKey="Muniozguren, Nerea" sort="Muniozguren, Nerea" uniqKey="Muniozguren N" first="Nerea" last="Muniozguren">Nerea Muniozguren</name>
<affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Epidemiology Unit, Public Health Department of Bizkaia</s1>
<s2>Galolatao</s2>
<s3>ESP</s3>
<sZ>21 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
</author>
<author><name sortKey="Norback, Dan" sort="Norback, Dan" uniqKey="Norback D" first="Dan" last="Norback">Dan Norback</name>
</author>
<author><name sortKey="Olivieri, Mario" sort="Olivieri, Mario" uniqKey="Olivieri M" first="Mario" last="Olivieri">Mario Olivieri</name>
</author>
<author><name sortKey="Payo, Felix" sort="Payo, Felix" uniqKey="Payo F" first="Félix" last="Payo">Félix Payo</name>
</author>
<author><name sortKey="Villani, Simona" sort="Villani, Simona" uniqKey="Villani S" first="Simona" last="Villani">Simona Villani</name>
</author>
<author><name sortKey="Van Sprundel, Marc" sort="Van Sprundel, Marc" uniqKey="Van Sprundel M" first="Marc" last="Van Sprundel">Marc Van Sprundel</name>
</author>
<author><name sortKey="Urrutia, Isabel" sort="Urrutia, Isabel" uniqKey="Urrutia I" first="Isabel" last="Urrutia">Isabel Urrutia</name>
</author>
<author><name sortKey="Wieslander, Gunilla" sort="Wieslander, Gunilla" uniqKey="Wieslander G" first="Gunilla" last="Wieslander">Gunilla Wieslander</name>
</author>
<author><name sortKey="Sunyer, Jordi" sort="Sunyer, Jordi" uniqKey="Sunyer J" first="Jordi" last="Sunyer">Jordi Sunyer</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
</author>
<author><name sortKey="Anto, Josep M" sort="Anto, Josep M" uniqKey="Anto J" first="Josep M." last="Anto">Josep M. Anto</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Lancet : (British edition)</title>
<title level="j" type="abbreviated">Lancet : (Br. ed.)</title>
<idno type="ISSN">0140-6736</idno>
<imprint><date when="2007">2007</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Lancet : (British edition)</title>
<title level="j" type="abbreviated">Lancet : (Br. ed.)</title>
<idno type="ISSN">0140-6736</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Asthma</term>
<term>Early stage</term>
<term>Epidemiology</term>
<term>International</term>
<term>Medicine</term>
<term>Occupational exposure</term>
<term>Population</term>
<term>Prospective</term>
<term>Public health</term>
<term>World</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Asthme</term>
<term>Exposition professionnelle</term>
<term>Stade précoce</term>
<term>International</term>
<term>Monde</term>
<term>Epidémiologie</term>
<term>Santé publique</term>
<term>Prospective</term>
<term>Population</term>
<term>Médecine</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Santé publique</term>
<term>Prospective</term>
<term>Médecine</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Background The role of exposure to substances in the workplace in new-onset asthma is not well characterised in population-based studies. We therefore aimed to estimate the relative and attributable risks of new-onset asthma in relation to occupations, work-related exposures, and inhalation accidents. Methods We studied prospectively 6837 participants from 13 countries who previously took part in the European Community Respiratory Health Survey (1990-95) and did not report respiratory symptoms or a history of asthma at the time of the first study. Asthma was assessed by methacholine challenge test and by questionnaire data on asthma symptoms. Exposures were defined by high-risk occupations, an asthma-specific job exposure matrix with additional expert judgment, and through self-report of acute inhalation events. Relative risks for new onset asthma were calculated with log-binomial models adjusted for age, sex, smoking, and study centre. Findings A significant excess asthma risk was seen after exposure to substances known to cause occupational asthma (Relative risk=1.6, 95% CI 1.1-2.3, p=0.017). Risks were highest for asthma defined by bronchial hyper-reactivity in addition to symptoms (2.4, 1.3-4.6, p=0.008). Of common occupations, a significant excess risk of asthma was seen for nursing (2.2, 1.3-4.0, p=0.007). Asthma risk was also increased in participants who reported an acute symptomatic inhalation event such as fire, mixing cleaning products, or chemical spills (RR=3.3, 95% CI 1.0-11.1, p=0.051). The population-attributable risk for adult asthma due to occupational exposures ranged from 10% to 25%, equivalent to an incidence of new-onset occupational asthma of 250-300 cases per million people per year. Interpretation Occupational exposures account for a substantial proportion of adult asthma incidence. The increased risk of asthma after inhalation accidents suggests that workers who have such accidents should be monitored closely.</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0140-6736</s0>
</fA01>
<fA02 i1="01"><s0>LANCAO</s0>
</fA02>
<fA03 i2="1"><s0>Lancet : (Br. ed.)</s0>
</fA03>
<fA05><s2>370</s2>
</fA05>
<fA06><s2>9584</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Exposure to substances in the workplace and new-onset asthma : an international prospective population-based study (ECRHS-II). Commentary</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>MALO (Jean-Luc)</s1>
<s9>comment.</s9>
</fA11>
<fA11 i1="02" i2="1"><s1>GAUTRIN (Denyse)</s1>
<s9>comment.</s9>
</fA11>
<fA11 i1="03" i2="1"><s1>KOGEVINAS (Manolis)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>ZOCK (Jan-Paul)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>JARVIS (Debbie)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>KROMHOUT (Hans)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>LILLIENBERG (Linnéa)</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>PLANA (Estel)</s1>
</fA11>
<fA11 i1="09" i2="1"><s1>RADON (Katja)</s1>
</fA11>
<fA11 i1="10" i2="1"><s1>TAREN (Kjell)</s1>
</fA11>
<fA11 i1="11" i2="1"><s1>ALLIKSOO (Ada)</s1>
</fA11>
<fA11 i1="12" i2="1"><s1>BENKE (Geza)</s1>
</fA11>
<fA11 i1="13" i2="1"><s1>BLANC (Paul D.)</s1>
</fA11>
<fA11 i1="14" i2="1"><s1>DAHLMAN-HOGLUND (Anna)</s1>
</fA11>
<fA11 i1="15" i2="1"><s1>D'ERRICO (Angelo)</s1>
</fA11>
<fA11 i1="16" i2="1"><s1>HERY (Michel)</s1>
</fA11>
<fA11 i1="17" i2="1"><s1>KENNEDY (Susan)</s1>
</fA11>
<fA11 i1="18" i2="1"><s1>KUNZLI (Nino)</s1>
</fA11>
<fA11 i1="19" i2="1"><s1>LEYNAERT (Bénédicte)</s1>
</fA11>
<fA11 i1="20" i2="1"><s1>MIRABELLI (Maria C.)</s1>
</fA11>
<fA11 i1="21" i2="1"><s1>MUNIOZGUREN (Nerea)</s1>
</fA11>
<fA11 i1="22" i2="1"><s1>NORBACK (Dan)</s1>
</fA11>
<fA11 i1="23" i2="1"><s1>OLIVIERI (Mario)</s1>
</fA11>
<fA11 i1="24" i2="1"><s1>PAYO (Félix)</s1>
</fA11>
<fA11 i1="25" i2="1"><s1>VILLANI (Simona)</s1>
</fA11>
<fA11 i1="26" i2="1"><s1>VAN SPRUNDEL (Marc)</s1>
</fA11>
<fA11 i1="27" i2="1"><s1>URRUTIA (Isabel)</s1>
</fA11>
<fA11 i1="28" i2="1"><s1>WIESLANDER (Gunilla)</s1>
</fA11>
<fA11 i1="29" i2="1"><s1>SUNYER (Jordi)</s1>
</fA11>
<fA11 i1="30" i2="1"><s1>ANTO (Josep M.)</s1>
</fA11>
<fA14 i1="01"><s1>Axe de recherche en santé respiratoire and Center for Asthma in the Workplace, Department of Chest Medicine, Sacré-Coeur Hospital</s1>
<s2>Montreal, H4J 1C5</s2>
<s3>CAN</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>18 aut.</sZ>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
<sZ>30 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Medical School, University of Crete</s1>
<s2>Heraklion</s2>
<s3>GRC</s3>
<sZ>3 aut.</sZ>
</fA14>
<fA14 i1="04"><s1>Respiratory Epidemiology and Public Health Group, National Heart and Lung Institute, Imperial College</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>5 aut.</sZ>
</fA14>
<fA14 i1="05"><s1>Division of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University</s1>
<s2>Utrecht</s2>
<s3>NLD</s3>
<sZ>6 aut.</sZ>
</fA14>
<fA14 i1="06"><s1>Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital</s1>
<s2>Goteborg</s2>
<s3>SWE</s3>
<sZ>7 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>14 aut.</sZ>
</fA14>
<fA14 i1="07"><s1>Unit for Occupational and Environmental Epidemiology and NetTeaching, Institute for Occupational and Environmental Medicine, Ludwig-Maximilians-University</s1>
<s2>Munich</s2>
<s3>DEU</s3>
<sZ>9 aut.</sZ>
</fA14>
<fA14 i1="08"><s1>Tartu University Clinics, Lung Clinic</s1>
<s2>Tartu</s2>
<s3>EST</s3>
<sZ>11 aut.</sZ>
</fA14>
<fA14 i1="09"><s1>Department of Epidemiology and Preventive Medicine, Monash University</s1>
<s2>VIC</s2>
<s3>AUS</s3>
<sZ>12 aut.</sZ>
</fA14>
<fA14 i1="10"><s1>Division of Occupational and Environmental Medicine, Department of Medicine, University of California San Francisco</s1>
<s2>San Francisco, CA</s2>
<s3>USA</s3>
<sZ>13 aut.</sZ>
</fA14>
<fA14 i1="11"><s1>Servizio Regionale di Epidemiologia</s1>
<s2>Turin</s2>
<s3>ITA</s3>
<sZ>15 aut.</sZ>
</fA14>
<fA14 i1="12"><s1>Institut National de Recherche et de Sécurité</s1>
<s2>Vandoeuvre -lès -Nancy</s2>
<s3>FRA</s3>
<sZ>16 aut.</sZ>
</fA14>
<fA14 i1="13"><s1>School of Occupational and Environmental Hygiene, University of British Columbia</s1>
<s2>Vancouver, BC</s2>
<s3>CAN</s3>
<sZ>17 aut.</sZ>
</fA14>
<fA14 i1="14"><s1>INSERM-The French Institute of Health and Medical Research, Unit 700-Epidemiology, Faculty of Medicine X Bichat</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>19 aut.</sZ>
</fA14>
<fA14 i1="15"><s1>Epidemiology Unit, Public Health Department of Bizkaia</s1>
<s2>Galolatao</s2>
<s3>ESP</s3>
<sZ>21 aut.</sZ>
</fA14>
<fA20><s2>295-297, 336-341 [9 p.]</s2>
</fA20>
<fA21><s1>2007</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>5004</s2>
<s5>354000162396270130</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2007 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>27 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>07-0364785</s0>
</fA47>
<fA60><s1>P</s1>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Lancet : (British edition)</s0>
</fA64>
<fA66 i1="01"><s0>GBR</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Background The role of exposure to substances in the workplace in new-onset asthma is not well characterised in population-based studies. We therefore aimed to estimate the relative and attributable risks of new-onset asthma in relation to occupations, work-related exposures, and inhalation accidents. Methods We studied prospectively 6837 participants from 13 countries who previously took part in the European Community Respiratory Health Survey (1990-95) and did not report respiratory symptoms or a history of asthma at the time of the first study. Asthma was assessed by methacholine challenge test and by questionnaire data on asthma symptoms. Exposures were defined by high-risk occupations, an asthma-specific job exposure matrix with additional expert judgment, and through self-report of acute inhalation events. Relative risks for new onset asthma were calculated with log-binomial models adjusted for age, sex, smoking, and study centre. Findings A significant excess asthma risk was seen after exposure to substances known to cause occupational asthma (Relative risk=1.6, 95% CI 1.1-2.3, p=0.017). Risks were highest for asthma defined by bronchial hyper-reactivity in addition to symptoms (2.4, 1.3-4.6, p=0.008). Of common occupations, a significant excess risk of asthma was seen for nursing (2.2, 1.3-4.0, p=0.007). Asthma risk was also increased in participants who reported an acute symptomatic inhalation event such as fire, mixing cleaning products, or chemical spills (RR=3.3, 95% CI 1.0-11.1, p=0.051). The population-attributable risk for adult asthma due to occupational exposures ranged from 10% to 25%, equivalent to an incidence of new-onset occupational asthma of 250-300 cases per million people per year. Interpretation Occupational exposures account for a substantial proportion of adult asthma incidence. The increased risk of asthma after inhalation accidents suggests that workers who have such accidents should be monitored closely.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B01</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B30B04</s0>
</fC02>
<fC02 i1="03" i2="X"><s0>002B11B</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Asthme</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Asthma</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Asma</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Exposition professionnelle</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Occupational exposure</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Exposición profesional</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Stade précoce</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Early stage</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Estadio precoz</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>International</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>International</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Internacional</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Monde</s0>
<s2>NG</s2>
<s5>06</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>World</s0>
<s2>NG</s2>
<s5>06</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Mundo</s0>
<s2>NG</s2>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Epidémiologie</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Epidemiology</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Epidemiología</s0>
<s5>08</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Santé publique</s0>
<s5>09</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Public health</s0>
<s5>09</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Salud pública</s0>
<s5>09</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Prospective</s0>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Prospective</s0>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Prospectiva</s0>
<s5>11</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Population</s0>
<s5>12</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Population</s0>
<s5>12</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Población</s0>
<s5>12</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Médecine</s0>
<s5>17</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Medicine</s0>
<s5>17</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Medicina</s0>
<s5>17</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Appareil respiratoire pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Respiratory disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Aparato respiratorio patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Bronchopneumopathie obstructive</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Obstructive pulmonary disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Broncopneumopatía obstructiva</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Bronche pathologie</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Bronchus disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Bronquio patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Poumon pathologie</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Lung disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Pulmón patología</s0>
<s5>40</s5>
</fC07>
<fN21><s1>232</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/PascalFrancis/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002605 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Curation/biblio.hfd -nk 002605 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Asie |area= AustralieFrV1 |flux= PascalFrancis |étape= Curation |type= RBID |clé= Pascal:07-0364785 |texte= Exposure to substances in the workplace and new-onset asthma : an international prospective population-based study (ECRHS-II). Commentary }}
![]() | This area was generated with Dilib version V0.6.33. | ![]() |