Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)
Identifieur interne : 002219 ( Ncbi/Merge ); précédent : 002218; suivant : 002220Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)
Auteurs : G. Davies [Royaume-Uni] ; N. Armstrong [Australie] ; J C Bis [États-Unis] ; J. Bressler [États-Unis] ; V. Chouraki [France, États-Unis] ; S. Giddaluru [Norvège] ; E. Hofer [Autriche] ; C A Ibrahim-Verbaas [Pays-Bas] ; M. Kirin [Royaume-Uni] ; J. Lahti [Finlande] ; S J Van Der Lee [Pays-Bas] ; S. Le Hellard [Norvège] ; T. Liu [Allemagne] ; R E Marioni [Royaume-Uni, Australie] ; C. Oldmeadow [Australie] ; I. Postmus [Pays-Bas] ; A V Smith [Islande] ; J A Smith [États-Unis] ; A. Thalamuthu [Australie] ; R. Thomson ; V. Vitart [Royaume-Uni] ; J. Wang [États-Unis] ; L. Yu [États-Unis] ; L. Zgaga [Irlande (pays), Croatie] ; W. Zhao [États-Unis] ; R. Boxall [Royaume-Uni] ; S E Harris [Royaume-Uni] ; W D Hill [Royaume-Uni] ; D C Liewald [Royaume-Uni] ; M. Luciano [Royaume-Uni] ; H. Adams [Pays-Bas] ; D. Ames [Australie] ; N. Amin [Pays-Bas] ; P. Amouyel [France] ; A A Assareh [Australie] ; R. Au [États-Unis] ; J T Becker [États-Unis] ; A. Beiser [États-Unis] ; C. Berr [France] ; L. Bertram [Allemagne, Royaume-Uni] ; E. Boerwinkle [États-Unis] ; B M Buckley [Irlande (pays)] ; H. Campbell [Royaume-Uni] ; J. Corley [Royaume-Uni] ; P L De Jager [États-Unis] ; C. Dufouil [France] ; J G Eriksson [Finlande] ; T. Espeseth [Norvège] ; J D Faul [États-Unis] ; I. Ford [Royaume-Uni] ; Generation Scotland [Royaume-Uni] ; R F Gottesman [États-Unis] ; M E Griswold [États-Unis] ; V. Gudnason [Islande] ; T B Harris [États-Unis] ; G. Heiss [États-Unis] ; A. Hofman [Pays-Bas] ; E G Holliday [Australie] ; J. Huffman [Royaume-Uni] ; S L R. Kardia [États-Unis] ; N. Kochan [Australie] ; D S Knopman [États-Unis] ; J B Kwok [Australie] ; J-C Lambert [France] ; T. Lee [Australie] ; G. Li [États-Unis] ; S-C Li [Allemagne] ; M. Loitfelder [Autriche] ; O L Lopez [États-Unis] ; A J Lundervold [Norvège] ; A. Lundqvist [Suède] ; K A Mather [Australie] ; S S Mirza [Pays-Bas] ; L. Nyberg [Suède] ; B A Oostra [Pays-Bas] ; A. Palotie [Royaume-Uni, Finlande] ; G. Papenberg [Allemagne, Suède] ; A. Pattie [Royaume-Uni] ; K. Petrovic [Autriche] ; O. Polasek [Croatie] ; B M Psaty [États-Unis] ; P. Redmond [Royaume-Uni] ; S. Reppermund [Australie] ; J I Rotter [États-Unis] ; H. Schmidt [Autriche] ; M. Schuur [Pays-Bas] ; P W Schofield [Australie] ; R J Scott [Australie] ; V M Steen [Norvège] ; D J Stott [Royaume-Uni] ; J C Van Swieten [Pays-Bas] ; K D Taylor [États-Unis] ; J. Trollor [Australie] ; S. Trompet [Pays-Bas] ; A G Uitterlinden [Pays-Bas] ; G. Weinstein [États-Unis] ; E. Widen [Finlande] ; B G Windham [États-Unis] ; J W Jukema [Pays-Bas] ; A F Wright [Royaume-Uni] ; M J Wright [Australie] ; Q. Yang [États-Unis] ; H. Amieva [France] ; J R Attia [Australie] ; D A Bennett [États-Unis] ; H. Brodaty [Australie] ; A J M. De Craen [Pays-Bas] ; C. Hayward [Royaume-Uni] ; M A Ikram [Pays-Bas] ; U. Lindenberger [Allemagne] ; L-G Nilsson [Suède] ; D J Porteous [Royaume-Uni] ; K. R Ikkönen [Finlande] ; I. Reinvang [Norvège] ; I. Rudan [Royaume-Uni] ; P S Sachdev [Australie] ; R. Schmidt [Autriche] ; P R Schofield [Australie] ; V. Srikanth [Australie] ; J M Starr [Royaume-Uni] ; S T Turner [États-Unis] ; D R Weir [États-Unis] ; J F Wilson [Royaume-Uni] ; C. Van Duijn [Pays-Bas] ; L. Launer [États-Unis] ; A L Fitzpatrick [États-Unis] ; S. Seshadri [États-Unis] ; T H Mosley [États-Unis] ; I J Deary [Royaume-Uni]Source :
- Molecular Psychiatry [ 1359-4184 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Athérosclérose (), Cognition (physiologie), Femelle, Humains, Mâle, Phénotype, Polymorphisme de nucléotide simple (génétique), Protéine HMGN1 (génétique), Prédisposition génétique à une maladie (génétique), Sujet âgé, Sujet âgé de 80 ans ou plus, Tests neuropsychologiques, Troubles de la cognition (génétique), Troubles de la cognition (étiologie), Écosse, Étude d'association pangénomique, Études de cohortes.
- MESH :
- génétique : Polymorphisme de nucléotide simple, Protéine HMGN1, Prédisposition génétique à une maladie, Troubles de la cognition.
- physiologie : Cognition.
- étiologie : Troubles de la cognition.
- Adulte d'âge moyen, Athérosclérose, Femelle, Humains, Mâle, Phénotype, Sujet âgé, Sujet âgé de 80 ans ou plus, Tests neuropsychologiques, Écosse, Étude d'association pangénomique, Études de cohortes.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Atherosclerosis (complications), Cognition (physiology), Cognition Disorders (etiology), Cognition Disorders (genetics), Cohort Studies, Female, Genetic Predisposition to Disease (genetics), Genome-Wide Association Study, HMGN1 Protein (genetics), Humans, Male, Middle Aged, Neuropsychological Tests, Phenotype, Polymorphism, Single Nucleotide (genetics), Scotland.
- MESH :
- chemical , genetics : HMGN1 Protein.
- geographic : Scotland.
- complications : Atherosclerosis.
- etiology : Cognition Disorders.
- genetics : Cognition Disorders, Genetic Predisposition to Disease, Polymorphism, Single Nucleotide.
- physiology : Cognition.
- Aged, Aged, 80 and over, Cohort Studies, Female, Genome-Wide Association Study, Humans, Male, Middle Aged, Neuropsychological Tests, Phenotype.
Abstract
General cognitive function is substantially heritable across the human life course from adolescence to old age. We investigated the genetic contribution to variation in this important, health- and well-being-related trait in middle-aged and older adults. We conducted a meta-analysis of genome-wide association studies of 31 cohorts (
Url:
DOI: 10.1038/mp.2014.188
PubMed: 25644384
PubMed Central: 4356746
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PMC:4356746Le document en format XML
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<author><name sortKey="Hofer, E" sort="Hofer, E" uniqKey="Hofer E" first="E" last="Hofer">E. Hofer</name>
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<affiliation wicri:level="1"><nlm:aff id="aff11"><institution>Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz</institution>
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<country xml:lang="fr">Autriche</country>
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<author><name sortKey="Ibrahim Verbaas, C A" sort="Ibrahim Verbaas, C A" uniqKey="Ibrahim Verbaas C" first="C A" last="Ibrahim-Verbaas">C A Ibrahim-Verbaas</name>
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<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<country xml:lang="fr">Pays-Bas</country>
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<author><name sortKey="Kirin, M" sort="Kirin, M" uniqKey="Kirin M" first="M" last="Kirin">M. Kirin</name>
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<country xml:lang="fr">Royaume-Uni</country>
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<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<affiliation wicri:level="1"><nlm:aff id="aff16"><institution>Folkhälsan Research Centre</institution>
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<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Van Der Lee, S J" sort="Van Der Lee, S J" uniqKey="Van Der Lee S" first="S J" last="Van Der Lee">S J Van Der Lee</name>
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<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Le Hellard, S" sort="Le Hellard, S" uniqKey="Le Hellard S" first="S" last="Le Hellard">S. Le Hellard</name>
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<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<country xml:lang="fr">Norvège</country>
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<author><name sortKey="Liu, T" sort="Liu, T" uniqKey="Liu T" first="T" last="Liu">T. Liu</name>
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</nlm:aff>
<country xml:lang="fr">Allemagne</country>
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<affiliation wicri:level="1"><nlm:aff id="aff18"><institution>Max Planck Institute for Molecular Genetics</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Marioni, R E" sort="Marioni, R E" uniqKey="Marioni R" first="R E" last="Marioni">R E Marioni</name>
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, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff20"><institution>Queensland Brain Institute, The University of Queensland</institution>
, Brisbane, QLD,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Oldmeadow, C" sort="Oldmeadow, C" uniqKey="Oldmeadow C" first="C" last="Oldmeadow">C. Oldmeadow</name>
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, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Postmus, I" sort="Postmus, I" uniqKey="Postmus I" first="I" last="Postmus">I. Postmus</name>
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, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff23"><institution>Netherlands Consortium for Healthy Ageing</institution>
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</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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</author>
<author><name sortKey="Smith, A V" sort="Smith, A V" uniqKey="Smith A" first="A V" last="Smith">A V Smith</name>
<affiliation wicri:level="1"><nlm:aff id="aff24"><institution>Icelandic Heart Association</institution>
, Kopavogur,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25"><institution>University of Iceland</institution>
, Reykjavik,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Smith, J A" sort="Smith, J A" uniqKey="Smith J" first="J A" last="Smith">J A Smith</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>Department of Epidemiology, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Thalamuthu, A" sort="Thalamuthu, A" uniqKey="Thalamuthu A" first="A" last="Thalamuthu">A. Thalamuthu</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Thomson, R" sort="Thomson, R" uniqKey="Thomson R" first="R" last="Thomson">R. Thomson</name>
<affiliation><nlm:aff id="aff28"><institution>Menzies Research Institute</institution>
, Hobart,<country>Tasmania</country>
</nlm:aff>
<wicri:noCountry code="nlm country">Tasmania</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Vitart, V" sort="Vitart, V" uniqKey="Vitart V" first="V" last="Vitart">V. Vitart</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, J" sort="Wang, J" uniqKey="Wang J" first="J" last="Wang">J. Wang</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff31"><institution>Department of Biostatistics, Boston University School of Public Health</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yu, L" sort="Yu, L" uniqKey="Yu L" first="L" last="Yu">L. Yu</name>
<affiliation wicri:level="1"><nlm:aff id="aff32"><institution>Rush Alzheimer's Disease Center, Rush University Medical Center</institution>
, Chicago, IL,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zgaga, L" sort="Zgaga, L" uniqKey="Zgaga L" first="L" last="Zgaga">L. Zgaga</name>
<affiliation wicri:level="1"><nlm:aff id="aff33"><institution>Department of Public Health and Primary Care, Trinity College Dublin</institution>
, Dublin,<country>Ireland</country>
</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff34"><institution>Andrija Stampar School of Public Health, Medical School, University of Zagreb</institution>
, Zagreb,<country>Croatia</country>
</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zhao, W" sort="Zhao, W" uniqKey="Zhao W" first="W" last="Zhao">W. Zhao</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>Department of Epidemiology, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boxall, R" sort="Boxall, R" uniqKey="Boxall R" first="R" last="Boxall">R. Boxall</name>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Harris, S E" sort="Harris, S E" uniqKey="Harris S" first="S E" last="Harris">S E Harris</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hill, W D" sort="Hill, W D" uniqKey="Hill W" first="W D" last="Hill">W D Hill</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Liewald, D C" sort="Liewald, D C" uniqKey="Liewald D" first="D C" last="Liewald">D C Liewald</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Luciano, M" sort="Luciano, M" uniqKey="Luciano M" first="M" last="Luciano">M. Luciano</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Adams, H" sort="Adams, H" uniqKey="Adams H" first="H" last="Adams">H. Adams</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ames, D" sort="Ames, D" uniqKey="Ames D" first="D" last="Ames">D. Ames</name>
<affiliation wicri:level="1"><nlm:aff id="aff37"><institution>National Ageing Research Institute, Royal Melbourne Hospital</institution>
, Melbourne, VIC,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff38"><institution>Academic Unit for Psychiatry of Old Age, St George's Hospital, University of Melbourne</institution>
, Kew,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amin, N" sort="Amin, N" uniqKey="Amin N" first="N" last="Amin">N. Amin</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amouyel, P" sort="Amouyel, P" uniqKey="Amouyel P" first="P" last="Amouyel">P. Amouyel</name>
<affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique</institution>
, Lille,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Assareh, A A" sort="Assareh, A A" uniqKey="Assareh A" first="A A" last="Assareh">A A Assareh</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Au, R" sort="Au, R" uniqKey="Au R" first="R" last="Au">R. Au</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Becker, J T" sort="Becker, J T" uniqKey="Becker J" first="J T" last="Becker">J T Becker</name>
<affiliation wicri:level="1"><nlm:aff id="aff39"><institution>Department of Neurology, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff40"><institution>Department of Psychiatry, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff41"><institution>Department of Psychology, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Beiser, A" sort="Beiser, A" uniqKey="Beiser A" first="A" last="Beiser">A. Beiser</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Berr, C" sort="Berr, C" uniqKey="Berr C" first="C" last="Berr">C. Berr</name>
<affiliation wicri:level="1"><nlm:aff id="aff42"><institution>Inserm, U106</institution>
, Montpellier,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff43"><institution>Université Montpellier I</institution>
, Montpellier,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bertram, L" sort="Bertram, L" uniqKey="Bertram L" first="L" last="Bertram">L. Bertram</name>
<affiliation wicri:level="1"><nlm:aff id="aff18"><institution>Max Planck Institute for Molecular Genetics</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff44"><institution>Faculty of Medicine, School of Public Health, Imperial College</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boerwinkle, E" sort="Boerwinkle, E" uniqKey="Boerwinkle E" first="E" last="Boerwinkle">E. Boerwinkle</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston</institution>
, Houston, TX,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff45"><institution>Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas Health Science Center at Houston</institution>
, Houston, TX,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff46"><institution>Human Genome Sequencing Center, Baylor College of Medicine</institution>
, Houston, TX,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Buckley, B M" sort="Buckley, B M" uniqKey="Buckley B" first="B M" last="Buckley">B M Buckley</name>
<affiliation wicri:level="1"><nlm:aff id="aff47"><institution>Department of Pharmacology and Therapeutics, University College Cork</institution>
, Cork,<country>Ireland</country>
</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Campbell, H" sort="Campbell, H" uniqKey="Campbell H" first="H" last="Campbell">H. Campbell</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Centre for Population Health Sciences, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Corley, J" sort="Corley, J" uniqKey="Corley J" first="J" last="Corley">J. Corley</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Jager, P L" sort="De Jager, P L" uniqKey="De Jager P" first="P L" last="De Jager">P L De Jager</name>
<affiliation wicri:level="1"><nlm:aff id="aff48"><institution>Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff49"><institution>Harvard Medical School</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff50"><institution>Program in Medical and Population Genetics, Broad Institute</institution>
, Cambridge, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dufouil, C" sort="Dufouil, C" uniqKey="Dufouil C" first="C" last="Dufouil">C. Dufouil</name>
<affiliation wicri:level="1"><nlm:aff id="aff51"><institution>Inserm U708, Neuroepidemiology</institution>
, Paris,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff52"><institution>Inserm U897, Université Bordeaux Segalen</institution>
, Bordeaux,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eriksson, J G" sort="Eriksson, J G" uniqKey="Eriksson J" first="J G" last="Eriksson">J G Eriksson</name>
<affiliation wicri:level="1"><nlm:aff id="aff16"><institution>Folkhälsan Research Centre</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff53"><institution>National Institute for Health and Welfare</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff54"><institution>Department of General Practice and Primary health Care, University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff55"><institution>Unit of General Practice, Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Espeseth, T" sort="Espeseth, T" uniqKey="Espeseth T" first="T" last="Espeseth">T. Espeseth</name>
<affiliation wicri:level="1"><nlm:aff id="aff56"><institution>K.G. Jebsen Centre for Psychosis Research, Norwegian Centre For Mental Disorders Research (NORMENT), Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo</institution>
, Oslo,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Psychology, University of Oslo</institution>
, Oslo,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Faul, J D" sort="Faul, J D" uniqKey="Faul J" first="J D" last="Faul">J D Faul</name>
<affiliation wicri:level="1"><nlm:aff id="aff58"><institution>Survey Research Center, Institute for Social Research, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ford, I" sort="Ford, I" uniqKey="Ford I" first="I" last="Ford">I. Ford</name>
<affiliation wicri:level="1"><nlm:aff id="aff59"><institution>Robertson Center for Biostatistics</institution>
, Glasgow,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Scotland, Generation" sort="Scotland, Generation" uniqKey="Scotland G" first="Generation" last="Scotland">Generation Scotland</name>
<affiliation wicri:level="1"><nlm:aff id="aff60"><institution>Generation Scotland, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gottesman, R F" sort="Gottesman, R F" uniqKey="Gottesman R" first="R F" last="Gottesman">R F Gottesman</name>
<affiliation wicri:level="1"><nlm:aff id="aff61"><institution>Department of Neurology, Johns Hopkins University School of Medicine</institution>
, Baltimore, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Griswold, M E" sort="Griswold, M E" uniqKey="Griswold M" first="M E" last="Griswold">M E Griswold</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Center of Biostatistics and Bioinformatics, University of Mississippi Medical Center</institution>
, Jackson, MS,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gudnason, V" sort="Gudnason, V" uniqKey="Gudnason V" first="V" last="Gudnason">V. Gudnason</name>
<affiliation wicri:level="1"><nlm:aff id="aff24"><institution>Icelandic Heart Association</institution>
, Kopavogur,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25"><institution>University of Iceland</institution>
, Reykjavik,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Harris, T B" sort="Harris, T B" uniqKey="Harris T" first="T B" last="Harris">T B Harris</name>
<affiliation wicri:level="1"><nlm:aff id="aff63"><institution>Intramural Research Program National Institutes on Aging, National Institutes of Health</institution>
, Bethesda, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Heiss, G" sort="Heiss, G" uniqKey="Heiss G" first="G" last="Heiss">G. Heiss</name>
<affiliation wicri:level="1"><nlm:aff id="aff64"><institution>Department of Epidemiology, University of North Carolina Gillings School of Global Public Health</institution>
, Chapel Hill, NC,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hofman, A" sort="Hofman, A" uniqKey="Hofman A" first="A" last="Hofman">A. Hofman</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Holliday, E G" sort="Holliday, E G" uniqKey="Holliday E" first="E G" last="Holliday">E G Holliday</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Huffman, J" sort="Huffman, J" uniqKey="Huffman J" first="J" last="Huffman">J. Huffman</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kardia, S L R" sort="Kardia, S L R" uniqKey="Kardia S" first="S L R" last="Kardia">S L R. Kardia</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>Department of Epidemiology, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kochan, N" sort="Kochan, N" uniqKey="Kochan N" first="N" last="Kochan">N. Kochan</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff65"><institution>Neuropsychiatric Institute, Prince of Wales Hospital</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Knopman, D S" sort="Knopman, D S" uniqKey="Knopman D" first="D S" last="Knopman">D S Knopman</name>
<affiliation wicri:level="1"><nlm:aff id="aff66"><institution>Department of Neurology, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kwok, J B" sort="Kwok, J B" uniqKey="Kwok J" first="J B" last="Kwok">J B Kwok</name>
<affiliation wicri:level="1"><nlm:aff id="aff67"><institution>Neuroscience Research Australia</institution>
, Randwick, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff68"><institution>School of Medical Sciences, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lambert, J C" sort="Lambert, J C" uniqKey="Lambert J" first="J-C" last="Lambert">J-C Lambert</name>
<affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique</institution>
, Lille,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lee, T" sort="Lee, T" uniqKey="Lee T" first="T" last="Lee">T. Lee</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff65"><institution>Neuropsychiatric Institute, Prince of Wales Hospital</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, G" sort="Li, G" uniqKey="Li G" first="G" last="Li">G. Li</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, S C" sort="Li, S C" uniqKey="Li S" first="S-C" last="Li">S-C Li</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff69"><institution>Technische Universität Dresden</institution>
, Dresden,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Loitfelder, M" sort="Loitfelder, M" uniqKey="Loitfelder M" first="M" last="Loitfelder">M. Loitfelder</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lopez, O L" sort="Lopez, O L" uniqKey="Lopez O" first="O L" last="Lopez">O L Lopez</name>
<affiliation wicri:level="1"><nlm:aff id="aff39"><institution>Department of Neurology, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lundervold, A J" sort="Lundervold, A J" uniqKey="Lundervold A" first="A J" last="Lundervold">A J Lundervold</name>
<affiliation wicri:level="1"><nlm:aff id="aff70"><institution>Department of Biological and Medical Psychology, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff71"><institution>Kavli Research Centre for Aging and Dementia, Haraldsplass Deaconess Hospital</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff72"><institution>K.G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lundqvist, A" sort="Lundqvist, A" uniqKey="Lundqvist A" first="A" last="Lundqvist">A. Lundqvist</name>
<affiliation wicri:level="1"><nlm:aff id="aff73"><institution>Umeå Center for Functional Brain Imaging (UFBI), Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mather, K A" sort="Mather, K A" uniqKey="Mather K" first="K A" last="Mather">K A Mather</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mirza, S S" sort="Mirza, S S" uniqKey="Mirza S" first="S S" last="Mirza">S S Mirza</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nyberg, L" sort="Nyberg, L" uniqKey="Nyberg L" first="L" last="Nyberg">L. Nyberg</name>
<affiliation wicri:level="1"><nlm:aff id="aff73"><institution>Umeå Center for Functional Brain Imaging (UFBI), Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff74"><institution>Department of Radiation Sciences, Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff75"><institution>Department of Integrative Medical Biology, Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Oostra, B A" sort="Oostra, B A" uniqKey="Oostra B" first="B A" last="Oostra">B A Oostra</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Palotie, A" sort="Palotie, A" uniqKey="Palotie A" first="A" last="Palotie">A. Palotie</name>
<affiliation wicri:level="1"><nlm:aff id="aff76"><institution>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff77"><institution>Institute for Molecular Medicine Finland (FIMM), University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff78"><institution>Department of Medical Genetics, University of Helsinki and University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Papenberg, G" sort="Papenberg, G" uniqKey="Papenberg G" first="G" last="Papenberg">G. Papenberg</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff79"><institution>Karolinska Institutet, Aging Research Center, Stockholm University</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pattie, A" sort="Pattie, A" uniqKey="Pattie A" first="A" last="Pattie">A. Pattie</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Petrovic, K" sort="Petrovic, K" uniqKey="Petrovic K" first="K" last="Petrovic">K. Petrovic</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Polasek, O" sort="Polasek, O" uniqKey="Polasek O" first="O" last="Polasek">O. Polasek</name>
<affiliation wicri:level="1"><nlm:aff id="aff80"><institution>Faculty of Medicine, Department of Public Health, University of Split</institution>
, Split,<country>Croatia</country>
</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Psaty, B M" sort="Psaty, B M" uniqKey="Psaty B" first="B M" last="Psaty">B M Psaty</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff81"><institution>Deparment of Epidemiology, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff82"><institution>Deparment of Health Services, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff83"><institution>Group Health Research Unit, Group Health Cooperative</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Redmond, P" sort="Redmond, P" uniqKey="Redmond P" first="P" last="Redmond">P. Redmond</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Reppermund, S" sort="Reppermund, S" uniqKey="Reppermund S" first="S" last="Reppermund">S. Reppermund</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rotter, J I" sort="Rotter, J I" uniqKey="Rotter J" first="J I" last="Rotter">J I Rotter</name>
<affiliation wicri:level="1"><nlm:aff id="aff84"><institution>Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff85"><institution>Division of Genetic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schmidt, H" sort="Schmidt, H" uniqKey="Schmidt H" first="H" last="Schmidt">H. Schmidt</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff86"><institution>Centre for Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schuur, M" sort="Schuur, M" uniqKey="Schuur M" first="M" last="Schuur">M. Schuur</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Neurology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schofield, P W" sort="Schofield, P W" uniqKey="Schofield P" first="P W" last="Schofield">P W Schofield</name>
<affiliation wicri:level="1"><nlm:aff id="aff87"><institution>School of Medicine and Public Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Scott, R J" sort="Scott, R J" uniqKey="Scott R" first="R J" last="Scott">R J Scott</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Steen, V M" sort="Steen, V M" uniqKey="Steen V" first="V M" last="Steen">V M Steen</name>
<affiliation wicri:level="1"><nlm:aff id="aff8"><institution>K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff9"><institution>Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stott, D J" sort="Stott, D J" uniqKey="Stott D" first="D J" last="Stott">D J Stott</name>
<affiliation wicri:level="1"><nlm:aff id="aff88"><institution>Institute of Cardiovascular and Medical Sciences, University of Glasgow</institution>
, Glasgow,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Swieten, J C" sort="Van Swieten, J C" uniqKey="Van Swieten J" first="J C" last="Van Swieten">J C Van Swieten</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Neurology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Taylor, K D" sort="Taylor, K D" uniqKey="Taylor K" first="K D" last="Taylor">K D Taylor</name>
<affiliation wicri:level="1"><nlm:aff id="aff84"><institution>Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff89"><institution>Department of Pediatrics, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Trollor, J" sort="Trollor, J" uniqKey="Trollor J" first="J" last="Trollor">J. Trollor</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff90"><institution>Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Trompet, S" sort="Trompet, S" uniqKey="Trompet S" first="S" last="Trompet">S. Trompet</name>
<affiliation wicri:level="1"><nlm:aff id="aff22"><institution>Department of Gerontology and Geriatrics, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Department of Cardiology, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Uitterlinden, A G" sort="Uitterlinden, A G" uniqKey="Uitterlinden A" first="A G" last="Uitterlinden">A G Uitterlinden</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff92"><institution>Department of Internal Medicine, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Weinstein, G" sort="Weinstein, G" uniqKey="Weinstein G" first="G" last="Weinstein">G. Weinstein</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Widen, E" sort="Widen, E" uniqKey="Widen E" first="E" last="Widen">E. Widen</name>
<affiliation wicri:level="1"><nlm:aff id="aff77"><institution>Institute for Molecular Medicine Finland (FIMM), University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Windham, B G" sort="Windham, B G" uniqKey="Windham B" first="B G" last="Windham">B G Windham</name>
<affiliation wicri:level="1"><nlm:aff id="aff93"><institution>Division of Geriatrics, Department of Medicine, University of Mississippi Medical Center</institution>
, Jackson, MS,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jukema, J W" sort="Jukema, J W" uniqKey="Jukema J" first="J W" last="Jukema">J W Jukema</name>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Department of Cardiology, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff94"><institution>Durrer Center for Cardiogenetic Research</institution>
, Amsterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff95"><institution>Interuniversity Cardiology Institute of the Netherlands</institution>
, Utrecht,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wright, A F" sort="Wright, A F" uniqKey="Wright A" first="A F" last="Wright">A F Wright</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wright, M J" sort="Wright, M J" uniqKey="Wright M" first="M J" last="Wright">M J Wright</name>
<affiliation wicri:level="1"><nlm:aff id="aff96"><institution>Neuroimaging Genetics Group, QIMR Berghofer Medical Research Institute</institution>
, Brisbane, QLD,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yang, Q" sort="Yang, Q" uniqKey="Yang Q" first="Q" last="Yang">Q. Yang</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff31"><institution>Department of Biostatistics, Boston University School of Public Health</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amieva, H" sort="Amieva, H" uniqKey="Amieva H" first="H" last="Amieva">H. Amieva</name>
<affiliation wicri:level="1"><nlm:aff id="aff52"><institution>Inserm U897, Université Bordeaux Segalen</institution>
, Bordeaux,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Attia, J R" sort="Attia, J R" uniqKey="Attia J" first="J R" last="Attia">J R Attia</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bennett, D A" sort="Bennett, D A" uniqKey="Bennett D" first="D A" last="Bennett">D A Bennett</name>
<affiliation wicri:level="1"><nlm:aff id="aff32"><institution>Rush Alzheimer's Disease Center, Rush University Medical Center</institution>
, Chicago, IL,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brodaty, H" sort="Brodaty, H" uniqKey="Brodaty H" first="H" last="Brodaty">H. Brodaty</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff97"><institution>Dementia Collaborative Research Centre, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Craen, A J M" sort="De Craen, A J M" uniqKey="De Craen A" first="A J M" last="De Craen">A J M. De Craen</name>
<affiliation wicri:level="1"><nlm:aff id="aff22"><institution>Department of Gerontology and Geriatrics, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff23"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hayward, C" sort="Hayward, C" uniqKey="Hayward C" first="C" last="Hayward">C. Hayward</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ikram, M A" sort="Ikram, M A" uniqKey="Ikram M" first="M A" last="Ikram">M A Ikram</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Neurology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff98"><institution>Department of Radiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lindenberger, U" sort="Lindenberger, U" uniqKey="Lindenberger U" first="U" last="Lindenberger">U. Lindenberger</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nilsson, L G" sort="Nilsson, L G" uniqKey="Nilsson L" first="L-G" last="Nilsson">L-G Nilsson</name>
<affiliation wicri:level="1"><nlm:aff id="aff99"><institution>ARC, Karolinska Institutet, Stockholm and UFBI, Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Porteous, D J" sort="Porteous, D J" uniqKey="Porteous D" first="D J" last="Porteous">D J Porteous</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff60"><institution>Generation Scotland, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="R Ikkonen, K" sort="R Ikkonen, K" uniqKey="R Ikkonen K" first="K" last="R Ikkönen">K. R Ikkönen</name>
<affiliation wicri:level="1"><nlm:aff id="aff15"><institution>Institute of Behavioural Sciences, University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Reinvang, I" sort="Reinvang, I" uniqKey="Reinvang I" first="I" last="Reinvang">I. Reinvang</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Psychology, University of Oslo</institution>
, Oslo,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rudan, I" sort="Rudan, I" uniqKey="Rudan I" first="I" last="Rudan">I. Rudan</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Centre for Population Health Sciences, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sachdev, P S" sort="Sachdev, P S" uniqKey="Sachdev P" first="P S" last="Sachdev">P S Sachdev</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff65"><institution>Neuropsychiatric Institute, Prince of Wales Hospital</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schmidt, R" sort="Schmidt, R" uniqKey="Schmidt R" first="R" last="Schmidt">R. Schmidt</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schofield, P R" sort="Schofield, P R" uniqKey="Schofield P" first="P R" last="Schofield">P R Schofield</name>
<affiliation wicri:level="1"><nlm:aff id="aff100"><institution>Neuroscience Research Australia</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff101"><institution>Faculty of Medicine, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Srikanth, V" sort="Srikanth, V" uniqKey="Srikanth V" first="V" last="Srikanth">V. Srikanth</name>
<affiliation><nlm:aff id="aff28"><institution>Menzies Research Institute</institution>
, Hobart,<country>Tasmania</country>
</nlm:aff>
<wicri:noCountry code="nlm country">Tasmania</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff102"><institution>Stroke and Ageing Research, Medicine, Southern Clinical School, Monash University</institution>
, Melbourne, VIC,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Starr, J M" sort="Starr, J M" uniqKey="Starr J" first="J M" last="Starr">J M Starr</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff103"><institution>Alzheimer Scotland Dementia Research Centre, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Turner, S T" sort="Turner, S T" uniqKey="Turner S" first="S T" last="Turner">S T Turner</name>
<affiliation wicri:level="1"><nlm:aff id="aff104"><institution>Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Weir, D R" sort="Weir, D R" uniqKey="Weir D" first="D R" last="Weir">D R Weir</name>
<affiliation wicri:level="1"><nlm:aff id="aff58"><institution>Survey Research Center, Institute for Social Research, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wilson, J F" sort="Wilson, J F" uniqKey="Wilson J" first="J F" last="Wilson">J F Wilson</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Centre for Population Health Sciences, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Duijn, C" sort="Van Duijn, C" uniqKey="Van Duijn C" first="C" last="Van Duijn">C. Van Duijn</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Launer, L" sort="Launer, L" uniqKey="Launer L" first="L" last="Launer">L. Launer</name>
<affiliation wicri:level="1"><nlm:aff id="aff63"><institution>Intramural Research Program National Institutes on Aging, National Institutes of Health</institution>
, Bethesda, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fitzpatrick, A L" sort="Fitzpatrick, A L" uniqKey="Fitzpatrick A" first="A L" last="Fitzpatrick">A L Fitzpatrick</name>
<affiliation wicri:level="1"><nlm:aff id="aff81"><institution>Deparment of Epidemiology, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff105"><institution>Department of Global Health, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Seshadri, S" sort="Seshadri, S" uniqKey="Seshadri S" first="S" last="Seshadri">S. Seshadri</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mosley, T H" sort="Mosley, T H" uniqKey="Mosley T" first="T H" last="Mosley">T H Mosley</name>
<affiliation wicri:level="1"><nlm:aff id="aff93"><institution>Division of Geriatrics, Department of Medicine, University of Mississippi Medical Center</institution>
, Jackson, MS,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Deary, I J" sort="Deary, I J" uniqKey="Deary I" first="I J" last="Deary">I J Deary</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">25644384</idno>
<idno type="pmc">4356746</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356746</idno>
<idno type="RBID">PMC:4356746</idno>
<idno type="doi">10.1038/mp.2014.188</idno>
<date when="2015">2015</date>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (<italic>N</italic>
=53 949)</title>
<author><name sortKey="Davies, G" sort="Davies, G" uniqKey="Davies G" first="G" last="Davies">G. Davies</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Armstrong, N" sort="Armstrong, N" uniqKey="Armstrong N" first="N" last="Armstrong">N. Armstrong</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>School of Mathematics and Statistics, University of Sydney</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bis, J C" sort="Bis, J C" uniqKey="Bis J" first="J C" last="Bis">J C Bis</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bressler, J" sort="Bressler, J" uniqKey="Bressler J" first="J" last="Bressler">J. Bressler</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston</institution>
, Houston, TX,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chouraki, V" sort="Chouraki, V" uniqKey="Chouraki V" first="V" last="Chouraki">V. Chouraki</name>
<affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique</institution>
, Lille,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Giddaluru, S" sort="Giddaluru, S" uniqKey="Giddaluru S" first="S" last="Giddaluru">S. Giddaluru</name>
<affiliation wicri:level="1"><nlm:aff id="aff8"><institution>K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff9"><institution>Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hofer, E" sort="Hofer, E" uniqKey="Hofer E" first="E" last="Hofer">E. Hofer</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff11"><institution>Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ibrahim Verbaas, C A" sort="Ibrahim Verbaas, C A" uniqKey="Ibrahim Verbaas C" first="C A" last="Ibrahim-Verbaas">C A Ibrahim-Verbaas</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Neurology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kirin, M" sort="Kirin, M" uniqKey="Kirin M" first="M" last="Kirin">M. Kirin</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Centre for Population Health Sciences, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lahti, J" sort="Lahti, J" uniqKey="Lahti J" first="J" last="Lahti">J. Lahti</name>
<affiliation wicri:level="1"><nlm:aff id="aff15"><institution>Institute of Behavioural Sciences, University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff16"><institution>Folkhälsan Research Centre</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Der Lee, S J" sort="Van Der Lee, S J" uniqKey="Van Der Lee S" first="S J" last="Van Der Lee">S J Van Der Lee</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Le Hellard, S" sort="Le Hellard, S" uniqKey="Le Hellard S" first="S" last="Le Hellard">S. Le Hellard</name>
<affiliation wicri:level="1"><nlm:aff id="aff8"><institution>K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff9"><institution>Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Liu, T" sort="Liu, T" uniqKey="Liu T" first="T" last="Liu">T. Liu</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff18"><institution>Max Planck Institute for Molecular Genetics</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Marioni, R E" sort="Marioni, R E" uniqKey="Marioni R" first="R E" last="Marioni">R E Marioni</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff20"><institution>Queensland Brain Institute, The University of Queensland</institution>
, Brisbane, QLD,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Oldmeadow, C" sort="Oldmeadow, C" uniqKey="Oldmeadow C" first="C" last="Oldmeadow">C. Oldmeadow</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Postmus, I" sort="Postmus, I" uniqKey="Postmus I" first="I" last="Postmus">I. Postmus</name>
<affiliation wicri:level="1"><nlm:aff id="aff22"><institution>Department of Gerontology and Geriatrics, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff23"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Smith, A V" sort="Smith, A V" uniqKey="Smith A" first="A V" last="Smith">A V Smith</name>
<affiliation wicri:level="1"><nlm:aff id="aff24"><institution>Icelandic Heart Association</institution>
, Kopavogur,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25"><institution>University of Iceland</institution>
, Reykjavik,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Smith, J A" sort="Smith, J A" uniqKey="Smith J" first="J A" last="Smith">J A Smith</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>Department of Epidemiology, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Thalamuthu, A" sort="Thalamuthu, A" uniqKey="Thalamuthu A" first="A" last="Thalamuthu">A. Thalamuthu</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Thomson, R" sort="Thomson, R" uniqKey="Thomson R" first="R" last="Thomson">R. Thomson</name>
<affiliation><nlm:aff id="aff28"><institution>Menzies Research Institute</institution>
, Hobart,<country>Tasmania</country>
</nlm:aff>
<wicri:noCountry code="nlm country">Tasmania</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Vitart, V" sort="Vitart, V" uniqKey="Vitart V" first="V" last="Vitart">V. Vitart</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, J" sort="Wang, J" uniqKey="Wang J" first="J" last="Wang">J. Wang</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff31"><institution>Department of Biostatistics, Boston University School of Public Health</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yu, L" sort="Yu, L" uniqKey="Yu L" first="L" last="Yu">L. Yu</name>
<affiliation wicri:level="1"><nlm:aff id="aff32"><institution>Rush Alzheimer's Disease Center, Rush University Medical Center</institution>
, Chicago, IL,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zgaga, L" sort="Zgaga, L" uniqKey="Zgaga L" first="L" last="Zgaga">L. Zgaga</name>
<affiliation wicri:level="1"><nlm:aff id="aff33"><institution>Department of Public Health and Primary Care, Trinity College Dublin</institution>
, Dublin,<country>Ireland</country>
</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff34"><institution>Andrija Stampar School of Public Health, Medical School, University of Zagreb</institution>
, Zagreb,<country>Croatia</country>
</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zhao, W" sort="Zhao, W" uniqKey="Zhao W" first="W" last="Zhao">W. Zhao</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>Department of Epidemiology, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boxall, R" sort="Boxall, R" uniqKey="Boxall R" first="R" last="Boxall">R. Boxall</name>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Harris, S E" sort="Harris, S E" uniqKey="Harris S" first="S E" last="Harris">S E Harris</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hill, W D" sort="Hill, W D" uniqKey="Hill W" first="W D" last="Hill">W D Hill</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Liewald, D C" sort="Liewald, D C" uniqKey="Liewald D" first="D C" last="Liewald">D C Liewald</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Luciano, M" sort="Luciano, M" uniqKey="Luciano M" first="M" last="Luciano">M. Luciano</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Adams, H" sort="Adams, H" uniqKey="Adams H" first="H" last="Adams">H. Adams</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ames, D" sort="Ames, D" uniqKey="Ames D" first="D" last="Ames">D. Ames</name>
<affiliation wicri:level="1"><nlm:aff id="aff37"><institution>National Ageing Research Institute, Royal Melbourne Hospital</institution>
, Melbourne, VIC,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff38"><institution>Academic Unit for Psychiatry of Old Age, St George's Hospital, University of Melbourne</institution>
, Kew,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amin, N" sort="Amin, N" uniqKey="Amin N" first="N" last="Amin">N. Amin</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amouyel, P" sort="Amouyel, P" uniqKey="Amouyel P" first="P" last="Amouyel">P. Amouyel</name>
<affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique</institution>
, Lille,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Assareh, A A" sort="Assareh, A A" uniqKey="Assareh A" first="A A" last="Assareh">A A Assareh</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Au, R" sort="Au, R" uniqKey="Au R" first="R" last="Au">R. Au</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Becker, J T" sort="Becker, J T" uniqKey="Becker J" first="J T" last="Becker">J T Becker</name>
<affiliation wicri:level="1"><nlm:aff id="aff39"><institution>Department of Neurology, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff40"><institution>Department of Psychiatry, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff41"><institution>Department of Psychology, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Beiser, A" sort="Beiser, A" uniqKey="Beiser A" first="A" last="Beiser">A. Beiser</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Berr, C" sort="Berr, C" uniqKey="Berr C" first="C" last="Berr">C. Berr</name>
<affiliation wicri:level="1"><nlm:aff id="aff42"><institution>Inserm, U106</institution>
, Montpellier,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff43"><institution>Université Montpellier I</institution>
, Montpellier,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bertram, L" sort="Bertram, L" uniqKey="Bertram L" first="L" last="Bertram">L. Bertram</name>
<affiliation wicri:level="1"><nlm:aff id="aff18"><institution>Max Planck Institute for Molecular Genetics</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff44"><institution>Faculty of Medicine, School of Public Health, Imperial College</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boerwinkle, E" sort="Boerwinkle, E" uniqKey="Boerwinkle E" first="E" last="Boerwinkle">E. Boerwinkle</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston</institution>
, Houston, TX,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff45"><institution>Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas Health Science Center at Houston</institution>
, Houston, TX,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff46"><institution>Human Genome Sequencing Center, Baylor College of Medicine</institution>
, Houston, TX,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Buckley, B M" sort="Buckley, B M" uniqKey="Buckley B" first="B M" last="Buckley">B M Buckley</name>
<affiliation wicri:level="1"><nlm:aff id="aff47"><institution>Department of Pharmacology and Therapeutics, University College Cork</institution>
, Cork,<country>Ireland</country>
</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Campbell, H" sort="Campbell, H" uniqKey="Campbell H" first="H" last="Campbell">H. Campbell</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Centre for Population Health Sciences, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Corley, J" sort="Corley, J" uniqKey="Corley J" first="J" last="Corley">J. Corley</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Jager, P L" sort="De Jager, P L" uniqKey="De Jager P" first="P L" last="De Jager">P L De Jager</name>
<affiliation wicri:level="1"><nlm:aff id="aff48"><institution>Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff49"><institution>Harvard Medical School</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff50"><institution>Program in Medical and Population Genetics, Broad Institute</institution>
, Cambridge, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dufouil, C" sort="Dufouil, C" uniqKey="Dufouil C" first="C" last="Dufouil">C. Dufouil</name>
<affiliation wicri:level="1"><nlm:aff id="aff51"><institution>Inserm U708, Neuroepidemiology</institution>
, Paris,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff52"><institution>Inserm U897, Université Bordeaux Segalen</institution>
, Bordeaux,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eriksson, J G" sort="Eriksson, J G" uniqKey="Eriksson J" first="J G" last="Eriksson">J G Eriksson</name>
<affiliation wicri:level="1"><nlm:aff id="aff16"><institution>Folkhälsan Research Centre</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff53"><institution>National Institute for Health and Welfare</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff54"><institution>Department of General Practice and Primary health Care, University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff55"><institution>Unit of General Practice, Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Espeseth, T" sort="Espeseth, T" uniqKey="Espeseth T" first="T" last="Espeseth">T. Espeseth</name>
<affiliation wicri:level="1"><nlm:aff id="aff56"><institution>K.G. Jebsen Centre for Psychosis Research, Norwegian Centre For Mental Disorders Research (NORMENT), Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo</institution>
, Oslo,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Psychology, University of Oslo</institution>
, Oslo,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Faul, J D" sort="Faul, J D" uniqKey="Faul J" first="J D" last="Faul">J D Faul</name>
<affiliation wicri:level="1"><nlm:aff id="aff58"><institution>Survey Research Center, Institute for Social Research, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ford, I" sort="Ford, I" uniqKey="Ford I" first="I" last="Ford">I. Ford</name>
<affiliation wicri:level="1"><nlm:aff id="aff59"><institution>Robertson Center for Biostatistics</institution>
, Glasgow,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Scotland, Generation" sort="Scotland, Generation" uniqKey="Scotland G" first="Generation" last="Scotland">Generation Scotland</name>
<affiliation wicri:level="1"><nlm:aff id="aff60"><institution>Generation Scotland, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gottesman, R F" sort="Gottesman, R F" uniqKey="Gottesman R" first="R F" last="Gottesman">R F Gottesman</name>
<affiliation wicri:level="1"><nlm:aff id="aff61"><institution>Department of Neurology, Johns Hopkins University School of Medicine</institution>
, Baltimore, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Griswold, M E" sort="Griswold, M E" uniqKey="Griswold M" first="M E" last="Griswold">M E Griswold</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Center of Biostatistics and Bioinformatics, University of Mississippi Medical Center</institution>
, Jackson, MS,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gudnason, V" sort="Gudnason, V" uniqKey="Gudnason V" first="V" last="Gudnason">V. Gudnason</name>
<affiliation wicri:level="1"><nlm:aff id="aff24"><institution>Icelandic Heart Association</institution>
, Kopavogur,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25"><institution>University of Iceland</institution>
, Reykjavik,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Harris, T B" sort="Harris, T B" uniqKey="Harris T" first="T B" last="Harris">T B Harris</name>
<affiliation wicri:level="1"><nlm:aff id="aff63"><institution>Intramural Research Program National Institutes on Aging, National Institutes of Health</institution>
, Bethesda, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Heiss, G" sort="Heiss, G" uniqKey="Heiss G" first="G" last="Heiss">G. Heiss</name>
<affiliation wicri:level="1"><nlm:aff id="aff64"><institution>Department of Epidemiology, University of North Carolina Gillings School of Global Public Health</institution>
, Chapel Hill, NC,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hofman, A" sort="Hofman, A" uniqKey="Hofman A" first="A" last="Hofman">A. Hofman</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Holliday, E G" sort="Holliday, E G" uniqKey="Holliday E" first="E G" last="Holliday">E G Holliday</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Huffman, J" sort="Huffman, J" uniqKey="Huffman J" first="J" last="Huffman">J. Huffman</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kardia, S L R" sort="Kardia, S L R" uniqKey="Kardia S" first="S L R" last="Kardia">S L R. Kardia</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>Department of Epidemiology, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kochan, N" sort="Kochan, N" uniqKey="Kochan N" first="N" last="Kochan">N. Kochan</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff65"><institution>Neuropsychiatric Institute, Prince of Wales Hospital</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Knopman, D S" sort="Knopman, D S" uniqKey="Knopman D" first="D S" last="Knopman">D S Knopman</name>
<affiliation wicri:level="1"><nlm:aff id="aff66"><institution>Department of Neurology, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kwok, J B" sort="Kwok, J B" uniqKey="Kwok J" first="J B" last="Kwok">J B Kwok</name>
<affiliation wicri:level="1"><nlm:aff id="aff67"><institution>Neuroscience Research Australia</institution>
, Randwick, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff68"><institution>School of Medical Sciences, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lambert, J C" sort="Lambert, J C" uniqKey="Lambert J" first="J-C" last="Lambert">J-C Lambert</name>
<affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique</institution>
, Lille,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lee, T" sort="Lee, T" uniqKey="Lee T" first="T" last="Lee">T. Lee</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff65"><institution>Neuropsychiatric Institute, Prince of Wales Hospital</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, G" sort="Li, G" uniqKey="Li G" first="G" last="Li">G. Li</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, S C" sort="Li, S C" uniqKey="Li S" first="S-C" last="Li">S-C Li</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff69"><institution>Technische Universität Dresden</institution>
, Dresden,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Loitfelder, M" sort="Loitfelder, M" uniqKey="Loitfelder M" first="M" last="Loitfelder">M. Loitfelder</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lopez, O L" sort="Lopez, O L" uniqKey="Lopez O" first="O L" last="Lopez">O L Lopez</name>
<affiliation wicri:level="1"><nlm:aff id="aff39"><institution>Department of Neurology, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lundervold, A J" sort="Lundervold, A J" uniqKey="Lundervold A" first="A J" last="Lundervold">A J Lundervold</name>
<affiliation wicri:level="1"><nlm:aff id="aff70"><institution>Department of Biological and Medical Psychology, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff71"><institution>Kavli Research Centre for Aging and Dementia, Haraldsplass Deaconess Hospital</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff72"><institution>K.G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lundqvist, A" sort="Lundqvist, A" uniqKey="Lundqvist A" first="A" last="Lundqvist">A. Lundqvist</name>
<affiliation wicri:level="1"><nlm:aff id="aff73"><institution>Umeå Center for Functional Brain Imaging (UFBI), Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mather, K A" sort="Mather, K A" uniqKey="Mather K" first="K A" last="Mather">K A Mather</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mirza, S S" sort="Mirza, S S" uniqKey="Mirza S" first="S S" last="Mirza">S S Mirza</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nyberg, L" sort="Nyberg, L" uniqKey="Nyberg L" first="L" last="Nyberg">L. Nyberg</name>
<affiliation wicri:level="1"><nlm:aff id="aff73"><institution>Umeå Center for Functional Brain Imaging (UFBI), Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff74"><institution>Department of Radiation Sciences, Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff75"><institution>Department of Integrative Medical Biology, Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Oostra, B A" sort="Oostra, B A" uniqKey="Oostra B" first="B A" last="Oostra">B A Oostra</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Palotie, A" sort="Palotie, A" uniqKey="Palotie A" first="A" last="Palotie">A. Palotie</name>
<affiliation wicri:level="1"><nlm:aff id="aff76"><institution>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff77"><institution>Institute for Molecular Medicine Finland (FIMM), University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff78"><institution>Department of Medical Genetics, University of Helsinki and University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Papenberg, G" sort="Papenberg, G" uniqKey="Papenberg G" first="G" last="Papenberg">G. Papenberg</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff79"><institution>Karolinska Institutet, Aging Research Center, Stockholm University</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pattie, A" sort="Pattie, A" uniqKey="Pattie A" first="A" last="Pattie">A. Pattie</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Petrovic, K" sort="Petrovic, K" uniqKey="Petrovic K" first="K" last="Petrovic">K. Petrovic</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Polasek, O" sort="Polasek, O" uniqKey="Polasek O" first="O" last="Polasek">O. Polasek</name>
<affiliation wicri:level="1"><nlm:aff id="aff80"><institution>Faculty of Medicine, Department of Public Health, University of Split</institution>
, Split,<country>Croatia</country>
</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Psaty, B M" sort="Psaty, B M" uniqKey="Psaty B" first="B M" last="Psaty">B M Psaty</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff81"><institution>Deparment of Epidemiology, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff82"><institution>Deparment of Health Services, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff83"><institution>Group Health Research Unit, Group Health Cooperative</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Redmond, P" sort="Redmond, P" uniqKey="Redmond P" first="P" last="Redmond">P. Redmond</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Reppermund, S" sort="Reppermund, S" uniqKey="Reppermund S" first="S" last="Reppermund">S. Reppermund</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rotter, J I" sort="Rotter, J I" uniqKey="Rotter J" first="J I" last="Rotter">J I Rotter</name>
<affiliation wicri:level="1"><nlm:aff id="aff84"><institution>Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff85"><institution>Division of Genetic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schmidt, H" sort="Schmidt, H" uniqKey="Schmidt H" first="H" last="Schmidt">H. Schmidt</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff86"><institution>Centre for Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schuur, M" sort="Schuur, M" uniqKey="Schuur M" first="M" last="Schuur">M. Schuur</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Neurology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schofield, P W" sort="Schofield, P W" uniqKey="Schofield P" first="P W" last="Schofield">P W Schofield</name>
<affiliation wicri:level="1"><nlm:aff id="aff87"><institution>School of Medicine and Public Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Scott, R J" sort="Scott, R J" uniqKey="Scott R" first="R J" last="Scott">R J Scott</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Steen, V M" sort="Steen, V M" uniqKey="Steen V" first="V M" last="Steen">V M Steen</name>
<affiliation wicri:level="1"><nlm:aff id="aff8"><institution>K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff9"><institution>Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stott, D J" sort="Stott, D J" uniqKey="Stott D" first="D J" last="Stott">D J Stott</name>
<affiliation wicri:level="1"><nlm:aff id="aff88"><institution>Institute of Cardiovascular and Medical Sciences, University of Glasgow</institution>
, Glasgow,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Swieten, J C" sort="Van Swieten, J C" uniqKey="Van Swieten J" first="J C" last="Van Swieten">J C Van Swieten</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Neurology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Taylor, K D" sort="Taylor, K D" uniqKey="Taylor K" first="K D" last="Taylor">K D Taylor</name>
<affiliation wicri:level="1"><nlm:aff id="aff84"><institution>Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff89"><institution>Department of Pediatrics, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Trollor, J" sort="Trollor, J" uniqKey="Trollor J" first="J" last="Trollor">J. Trollor</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff90"><institution>Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Trompet, S" sort="Trompet, S" uniqKey="Trompet S" first="S" last="Trompet">S. Trompet</name>
<affiliation wicri:level="1"><nlm:aff id="aff22"><institution>Department of Gerontology and Geriatrics, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Department of Cardiology, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Uitterlinden, A G" sort="Uitterlinden, A G" uniqKey="Uitterlinden A" first="A G" last="Uitterlinden">A G Uitterlinden</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff92"><institution>Department of Internal Medicine, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Weinstein, G" sort="Weinstein, G" uniqKey="Weinstein G" first="G" last="Weinstein">G. Weinstein</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Widen, E" sort="Widen, E" uniqKey="Widen E" first="E" last="Widen">E. Widen</name>
<affiliation wicri:level="1"><nlm:aff id="aff77"><institution>Institute for Molecular Medicine Finland (FIMM), University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Windham, B G" sort="Windham, B G" uniqKey="Windham B" first="B G" last="Windham">B G Windham</name>
<affiliation wicri:level="1"><nlm:aff id="aff93"><institution>Division of Geriatrics, Department of Medicine, University of Mississippi Medical Center</institution>
, Jackson, MS,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jukema, J W" sort="Jukema, J W" uniqKey="Jukema J" first="J W" last="Jukema">J W Jukema</name>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Department of Cardiology, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff94"><institution>Durrer Center for Cardiogenetic Research</institution>
, Amsterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff95"><institution>Interuniversity Cardiology Institute of the Netherlands</institution>
, Utrecht,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wright, A F" sort="Wright, A F" uniqKey="Wright A" first="A F" last="Wright">A F Wright</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wright, M J" sort="Wright, M J" uniqKey="Wright M" first="M J" last="Wright">M J Wright</name>
<affiliation wicri:level="1"><nlm:aff id="aff96"><institution>Neuroimaging Genetics Group, QIMR Berghofer Medical Research Institute</institution>
, Brisbane, QLD,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yang, Q" sort="Yang, Q" uniqKey="Yang Q" first="Q" last="Yang">Q. Yang</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff31"><institution>Department of Biostatistics, Boston University School of Public Health</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amieva, H" sort="Amieva, H" uniqKey="Amieva H" first="H" last="Amieva">H. Amieva</name>
<affiliation wicri:level="1"><nlm:aff id="aff52"><institution>Inserm U897, Université Bordeaux Segalen</institution>
, Bordeaux,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Attia, J R" sort="Attia, J R" uniqKey="Attia J" first="J R" last="Attia">J R Attia</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bennett, D A" sort="Bennett, D A" uniqKey="Bennett D" first="D A" last="Bennett">D A Bennett</name>
<affiliation wicri:level="1"><nlm:aff id="aff32"><institution>Rush Alzheimer's Disease Center, Rush University Medical Center</institution>
, Chicago, IL,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brodaty, H" sort="Brodaty, H" uniqKey="Brodaty H" first="H" last="Brodaty">H. Brodaty</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff97"><institution>Dementia Collaborative Research Centre, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Craen, A J M" sort="De Craen, A J M" uniqKey="De Craen A" first="A J M" last="De Craen">A J M. De Craen</name>
<affiliation wicri:level="1"><nlm:aff id="aff22"><institution>Department of Gerontology and Geriatrics, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff23"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hayward, C" sort="Hayward, C" uniqKey="Hayward C" first="C" last="Hayward">C. Hayward</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ikram, M A" sort="Ikram, M A" uniqKey="Ikram M" first="M A" last="Ikram">M A Ikram</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Neurology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff98"><institution>Department of Radiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lindenberger, U" sort="Lindenberger, U" uniqKey="Lindenberger U" first="U" last="Lindenberger">U. Lindenberger</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nilsson, L G" sort="Nilsson, L G" uniqKey="Nilsson L" first="L-G" last="Nilsson">L-G Nilsson</name>
<affiliation wicri:level="1"><nlm:aff id="aff99"><institution>ARC, Karolinska Institutet, Stockholm and UFBI, Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Porteous, D J" sort="Porteous, D J" uniqKey="Porteous D" first="D J" last="Porteous">D J Porteous</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff60"><institution>Generation Scotland, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="R Ikkonen, K" sort="R Ikkonen, K" uniqKey="R Ikkonen K" first="K" last="R Ikkönen">K. R Ikkönen</name>
<affiliation wicri:level="1"><nlm:aff id="aff15"><institution>Institute of Behavioural Sciences, University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Reinvang, I" sort="Reinvang, I" uniqKey="Reinvang I" first="I" last="Reinvang">I. Reinvang</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Psychology, University of Oslo</institution>
, Oslo,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rudan, I" sort="Rudan, I" uniqKey="Rudan I" first="I" last="Rudan">I. Rudan</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Centre for Population Health Sciences, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sachdev, P S" sort="Sachdev, P S" uniqKey="Sachdev P" first="P S" last="Sachdev">P S Sachdev</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff65"><institution>Neuropsychiatric Institute, Prince of Wales Hospital</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schmidt, R" sort="Schmidt, R" uniqKey="Schmidt R" first="R" last="Schmidt">R. Schmidt</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schofield, P R" sort="Schofield, P R" uniqKey="Schofield P" first="P R" last="Schofield">P R Schofield</name>
<affiliation wicri:level="1"><nlm:aff id="aff100"><institution>Neuroscience Research Australia</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff101"><institution>Faculty of Medicine, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Srikanth, V" sort="Srikanth, V" uniqKey="Srikanth V" first="V" last="Srikanth">V. Srikanth</name>
<affiliation><nlm:aff id="aff28"><institution>Menzies Research Institute</institution>
, Hobart,<country>Tasmania</country>
</nlm:aff>
<wicri:noCountry code="nlm country">Tasmania</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff102"><institution>Stroke and Ageing Research, Medicine, Southern Clinical School, Monash University</institution>
, Melbourne, VIC,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Starr, J M" sort="Starr, J M" uniqKey="Starr J" first="J M" last="Starr">J M Starr</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff103"><institution>Alzheimer Scotland Dementia Research Centre, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Turner, S T" sort="Turner, S T" uniqKey="Turner S" first="S T" last="Turner">S T Turner</name>
<affiliation wicri:level="1"><nlm:aff id="aff104"><institution>Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Weir, D R" sort="Weir, D R" uniqKey="Weir D" first="D R" last="Weir">D R Weir</name>
<affiliation wicri:level="1"><nlm:aff id="aff58"><institution>Survey Research Center, Institute for Social Research, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wilson, J F" sort="Wilson, J F" uniqKey="Wilson J" first="J F" last="Wilson">J F Wilson</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Centre for Population Health Sciences, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Duijn, C" sort="Van Duijn, C" uniqKey="Van Duijn C" first="C" last="Van Duijn">C. Van Duijn</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Launer, L" sort="Launer, L" uniqKey="Launer L" first="L" last="Launer">L. Launer</name>
<affiliation wicri:level="1"><nlm:aff id="aff63"><institution>Intramural Research Program National Institutes on Aging, National Institutes of Health</institution>
, Bethesda, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fitzpatrick, A L" sort="Fitzpatrick, A L" uniqKey="Fitzpatrick A" first="A L" last="Fitzpatrick">A L Fitzpatrick</name>
<affiliation wicri:level="1"><nlm:aff id="aff81"><institution>Deparment of Epidemiology, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff105"><institution>Department of Global Health, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Seshadri, S" sort="Seshadri, S" uniqKey="Seshadri S" first="S" last="Seshadri">S. Seshadri</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mosley, T H" sort="Mosley, T H" uniqKey="Mosley T" first="T H" last="Mosley">T H Mosley</name>
<affiliation wicri:level="1"><nlm:aff id="aff93"><institution>Division of Geriatrics, Department of Medicine, University of Mississippi Medical Center</institution>
, Jackson, MS,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Deary, I J" sort="Deary, I J" uniqKey="Deary I" first="I J" last="Deary">I J Deary</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Molecular Psychiatry</title>
<idno type="ISSN">1359-4184</idno>
<idno type="eISSN">1476-5578</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Atherosclerosis (complications)</term>
<term>Cognition (physiology)</term>
<term>Cognition Disorders (etiology)</term>
<term>Cognition Disorders (genetics)</term>
<term>Cohort Studies</term>
<term>Female</term>
<term>Genetic Predisposition to Disease (genetics)</term>
<term>Genome-Wide Association Study</term>
<term>HMGN1 Protein (genetics)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
<term>Phenotype</term>
<term>Polymorphism, Single Nucleotide (genetics)</term>
<term>Scotland</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Athérosclérose ()</term>
<term>Cognition (physiologie)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Phénotype</term>
<term>Polymorphisme de nucléotide simple (génétique)</term>
<term>Protéine HMGN1 (génétique)</term>
<term>Prédisposition génétique à une maladie (génétique)</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tests neuropsychologiques</term>
<term>Troubles de la cognition (génétique)</term>
<term>Troubles de la cognition (étiologie)</term>
<term>Écosse</term>
<term>Étude d'association pangénomique</term>
<term>Études de cohortes</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>HMGN1 Protein</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Scotland</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Atherosclerosis</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cognition Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Cognition Disorders</term>
<term>Genetic Predisposition to Disease</term>
<term>Polymorphism, Single Nucleotide</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Polymorphisme de nucléotide simple</term>
<term>Protéine HMGN1</term>
<term>Prédisposition génétique à une maladie</term>
<term>Troubles de la cognition</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Cognition</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Cognition</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Troubles de la cognition</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Cohort Studies</term>
<term>Female</term>
<term>Genome-Wide Association Study</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
<term>Phenotype</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Athérosclérose</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Phénotype</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tests neuropsychologiques</term>
<term>Écosse</term>
<term>Étude d'association pangénomique</term>
<term>Études de cohortes</term>
</keywords>
</textClass>
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<front><div type="abstract" xml:lang="en"><p>General cognitive function is substantially heritable across the human life course from adolescence to old age. We investigated the genetic contribution to variation in this important, health- and well-being-related trait in middle-aged and older adults. We conducted a meta-analysis of genome-wide association studies of 31 cohorts (<italic>N</italic>
=53 949) in which the participants had undertaken multiple, diverse cognitive tests. A general cognitive function phenotype was tested for, and created in each cohort by principal component analysis. We report 13 genome-wide significant single-nucleotide polymorphism (SNP) associations in three genomic regions, 6q16.1, 14q12 and 19q13.32 (best SNP and closest gene, respectively: rs10457441, <italic>P</italic>
=3.93 × 10<sup>−9</sup>
, <italic>MIR2113</italic>
; rs17522122, <italic>P</italic>
=2.55 × 10<sup>−8</sup>
, <italic>AKAP6</italic>
; rs10119, <italic>P</italic>
=5.67 × 10<sup>−9</sup>
, <italic>APOE/TOMM40</italic>
). We report one gene-based significant association with the <italic>HMGN1</italic>
gene located on chromosome 21 (<italic>P</italic>
=1 × 10<sup>−6</sup>
). These genes have previously been associated with neuropsychiatric phenotypes. Meta-analysis results are consistent with a polygenic model of inheritance. To estimate SNP-based heritability, the genome-wide complex trait analysis procedure was applied to two large cohorts, the Atherosclerosis Risk in Communities Study (<italic>N</italic>
=6617) and the Health and Retirement Study (<italic>N</italic>
=5976). The proportion of phenotypic variation accounted for by all genotyped common SNPs was 29% (s.e.=5%) and 28% (s.e.=7%), respectively. Using polygenic prediction analysis, ~1.2% of the variance in general cognitive function was predicted in the Generation Scotland cohort (<italic>N</italic>
=5487; <italic>P</italic>
=1.5 × 10<sup>−17</sup>
). In hypothesis-driven tests, there was significant association between general cognitive function and four genes previously associated with Alzheimer's disease: <italic>TOMM40</italic>
, <italic>APOE</italic>
, <italic>ABCG1</italic>
and <italic>MEF2C</italic>
.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Vallejo, An" uniqKey="Vallejo A">AN Vallejo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Laurent, S" uniqKey="Laurent S">S Laurent</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Vaz Fragoso, A" uniqKey="Vaz Fragoso A">A Vaz Fragoso</name>
</author>
<author><name sortKey="Gill, Tm" uniqKey="Gill T">TM Gill</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bolignano, D" uniqKey="Bolignano D">D Bolignano</name>
</author>
<author><name sortKey="Mattace Raso, F" uniqKey="Mattace Raso F">F Mattace-Raso</name>
</author>
<author><name sortKey="Sijbrands, Ejg" uniqKey="Sijbrands E">EJG Sijbrands</name>
</author>
<author><name sortKey="Zoccali, C" uniqKey="Zoccali C">C Zoccali</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ferrari, E" uniqKey="Ferrari E">E Ferrari</name>
</author>
<author><name sortKey="Magri, F" uniqKey="Magri F">F Magri</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lindenberger, U" uniqKey="Lindenberger U">U Lindenberger</name>
</author>
<author><name sortKey="Baltes, Pb" uniqKey="Baltes P">PB Baltes</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Pathai, S" uniqKey="Pathai S">S Pathai</name>
</author>
<author><name sortKey="Shiels, Pg" uniqKey="Shiels P">PG Shiels</name>
</author>
<author><name sortKey="Lawn, Sd" uniqKey="Lawn S">SD Lawn</name>
</author>
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</TEI>
<double pmid="25644384"><pmc><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (<italic>N</italic>
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, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
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<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>School of Mathematics and Statistics, University of Sydney</institution>
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</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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, Seattle, WA,<country>USA</country>
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<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<country xml:lang="fr">États-Unis</country>
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<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<country xml:lang="fr">États-Unis</country>
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<country xml:lang="fr">Norvège</country>
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<country xml:lang="fr">Pays-Bas</country>
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<affiliation wicri:level="1"><nlm:aff id="aff9"><institution>Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Liu, T" sort="Liu, T" uniqKey="Liu T" first="T" last="Liu">T. Liu</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff18"><institution>Max Planck Institute for Molecular Genetics</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Marioni, R E" sort="Marioni, R E" uniqKey="Marioni R" first="R E" last="Marioni">R E Marioni</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff20"><institution>Queensland Brain Institute, The University of Queensland</institution>
, Brisbane, QLD,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Oldmeadow, C" sort="Oldmeadow, C" uniqKey="Oldmeadow C" first="C" last="Oldmeadow">C. Oldmeadow</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Postmus, I" sort="Postmus, I" uniqKey="Postmus I" first="I" last="Postmus">I. Postmus</name>
<affiliation wicri:level="1"><nlm:aff id="aff22"><institution>Department of Gerontology and Geriatrics, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff23"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Smith, A V" sort="Smith, A V" uniqKey="Smith A" first="A V" last="Smith">A V Smith</name>
<affiliation wicri:level="1"><nlm:aff id="aff24"><institution>Icelandic Heart Association</institution>
, Kopavogur,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25"><institution>University of Iceland</institution>
, Reykjavik,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Smith, J A" sort="Smith, J A" uniqKey="Smith J" first="J A" last="Smith">J A Smith</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>Department of Epidemiology, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Thalamuthu, A" sort="Thalamuthu, A" uniqKey="Thalamuthu A" first="A" last="Thalamuthu">A. Thalamuthu</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Thomson, R" sort="Thomson, R" uniqKey="Thomson R" first="R" last="Thomson">R. Thomson</name>
<affiliation><nlm:aff id="aff28"><institution>Menzies Research Institute</institution>
, Hobart,<country>Tasmania</country>
</nlm:aff>
<wicri:noCountry code="nlm country">Tasmania</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Vitart, V" sort="Vitart, V" uniqKey="Vitart V" first="V" last="Vitart">V. Vitart</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, J" sort="Wang, J" uniqKey="Wang J" first="J" last="Wang">J. Wang</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff31"><institution>Department of Biostatistics, Boston University School of Public Health</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yu, L" sort="Yu, L" uniqKey="Yu L" first="L" last="Yu">L. Yu</name>
<affiliation wicri:level="1"><nlm:aff id="aff32"><institution>Rush Alzheimer's Disease Center, Rush University Medical Center</institution>
, Chicago, IL,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zgaga, L" sort="Zgaga, L" uniqKey="Zgaga L" first="L" last="Zgaga">L. Zgaga</name>
<affiliation wicri:level="1"><nlm:aff id="aff33"><institution>Department of Public Health and Primary Care, Trinity College Dublin</institution>
, Dublin,<country>Ireland</country>
</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff34"><institution>Andrija Stampar School of Public Health, Medical School, University of Zagreb</institution>
, Zagreb,<country>Croatia</country>
</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zhao, W" sort="Zhao, W" uniqKey="Zhao W" first="W" last="Zhao">W. Zhao</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>Department of Epidemiology, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boxall, R" sort="Boxall, R" uniqKey="Boxall R" first="R" last="Boxall">R. Boxall</name>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Harris, S E" sort="Harris, S E" uniqKey="Harris S" first="S E" last="Harris">S E Harris</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hill, W D" sort="Hill, W D" uniqKey="Hill W" first="W D" last="Hill">W D Hill</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Liewald, D C" sort="Liewald, D C" uniqKey="Liewald D" first="D C" last="Liewald">D C Liewald</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Luciano, M" sort="Luciano, M" uniqKey="Luciano M" first="M" last="Luciano">M. Luciano</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Adams, H" sort="Adams, H" uniqKey="Adams H" first="H" last="Adams">H. Adams</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ames, D" sort="Ames, D" uniqKey="Ames D" first="D" last="Ames">D. Ames</name>
<affiliation wicri:level="1"><nlm:aff id="aff37"><institution>National Ageing Research Institute, Royal Melbourne Hospital</institution>
, Melbourne, VIC,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff38"><institution>Academic Unit for Psychiatry of Old Age, St George's Hospital, University of Melbourne</institution>
, Kew,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amin, N" sort="Amin, N" uniqKey="Amin N" first="N" last="Amin">N. Amin</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amouyel, P" sort="Amouyel, P" uniqKey="Amouyel P" first="P" last="Amouyel">P. Amouyel</name>
<affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique</institution>
, Lille,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Assareh, A A" sort="Assareh, A A" uniqKey="Assareh A" first="A A" last="Assareh">A A Assareh</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Au, R" sort="Au, R" uniqKey="Au R" first="R" last="Au">R. Au</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Becker, J T" sort="Becker, J T" uniqKey="Becker J" first="J T" last="Becker">J T Becker</name>
<affiliation wicri:level="1"><nlm:aff id="aff39"><institution>Department of Neurology, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff40"><institution>Department of Psychiatry, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff41"><institution>Department of Psychology, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Beiser, A" sort="Beiser, A" uniqKey="Beiser A" first="A" last="Beiser">A. Beiser</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Berr, C" sort="Berr, C" uniqKey="Berr C" first="C" last="Berr">C. Berr</name>
<affiliation wicri:level="1"><nlm:aff id="aff42"><institution>Inserm, U106</institution>
, Montpellier,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff43"><institution>Université Montpellier I</institution>
, Montpellier,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bertram, L" sort="Bertram, L" uniqKey="Bertram L" first="L" last="Bertram">L. Bertram</name>
<affiliation wicri:level="1"><nlm:aff id="aff18"><institution>Max Planck Institute for Molecular Genetics</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff44"><institution>Faculty of Medicine, School of Public Health, Imperial College</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boerwinkle, E" sort="Boerwinkle, E" uniqKey="Boerwinkle E" first="E" last="Boerwinkle">E. Boerwinkle</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston</institution>
, Houston, TX,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff45"><institution>Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas Health Science Center at Houston</institution>
, Houston, TX,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff46"><institution>Human Genome Sequencing Center, Baylor College of Medicine</institution>
, Houston, TX,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Buckley, B M" sort="Buckley, B M" uniqKey="Buckley B" first="B M" last="Buckley">B M Buckley</name>
<affiliation wicri:level="1"><nlm:aff id="aff47"><institution>Department of Pharmacology and Therapeutics, University College Cork</institution>
, Cork,<country>Ireland</country>
</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Campbell, H" sort="Campbell, H" uniqKey="Campbell H" first="H" last="Campbell">H. Campbell</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Centre for Population Health Sciences, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Corley, J" sort="Corley, J" uniqKey="Corley J" first="J" last="Corley">J. Corley</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Jager, P L" sort="De Jager, P L" uniqKey="De Jager P" first="P L" last="De Jager">P L De Jager</name>
<affiliation wicri:level="1"><nlm:aff id="aff48"><institution>Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff49"><institution>Harvard Medical School</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff50"><institution>Program in Medical and Population Genetics, Broad Institute</institution>
, Cambridge, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dufouil, C" sort="Dufouil, C" uniqKey="Dufouil C" first="C" last="Dufouil">C. Dufouil</name>
<affiliation wicri:level="1"><nlm:aff id="aff51"><institution>Inserm U708, Neuroepidemiology</institution>
, Paris,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff52"><institution>Inserm U897, Université Bordeaux Segalen</institution>
, Bordeaux,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eriksson, J G" sort="Eriksson, J G" uniqKey="Eriksson J" first="J G" last="Eriksson">J G Eriksson</name>
<affiliation wicri:level="1"><nlm:aff id="aff16"><institution>Folkhälsan Research Centre</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff53"><institution>National Institute for Health and Welfare</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff54"><institution>Department of General Practice and Primary health Care, University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff55"><institution>Unit of General Practice, Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Espeseth, T" sort="Espeseth, T" uniqKey="Espeseth T" first="T" last="Espeseth">T. Espeseth</name>
<affiliation wicri:level="1"><nlm:aff id="aff56"><institution>K.G. Jebsen Centre for Psychosis Research, Norwegian Centre For Mental Disorders Research (NORMENT), Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo</institution>
, Oslo,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Psychology, University of Oslo</institution>
, Oslo,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Faul, J D" sort="Faul, J D" uniqKey="Faul J" first="J D" last="Faul">J D Faul</name>
<affiliation wicri:level="1"><nlm:aff id="aff58"><institution>Survey Research Center, Institute for Social Research, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ford, I" sort="Ford, I" uniqKey="Ford I" first="I" last="Ford">I. Ford</name>
<affiliation wicri:level="1"><nlm:aff id="aff59"><institution>Robertson Center for Biostatistics</institution>
, Glasgow,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Scotland, Generation" sort="Scotland, Generation" uniqKey="Scotland G" first="Generation" last="Scotland">Generation Scotland</name>
<affiliation wicri:level="1"><nlm:aff id="aff60"><institution>Generation Scotland, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gottesman, R F" sort="Gottesman, R F" uniqKey="Gottesman R" first="R F" last="Gottesman">R F Gottesman</name>
<affiliation wicri:level="1"><nlm:aff id="aff61"><institution>Department of Neurology, Johns Hopkins University School of Medicine</institution>
, Baltimore, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Griswold, M E" sort="Griswold, M E" uniqKey="Griswold M" first="M E" last="Griswold">M E Griswold</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Center of Biostatistics and Bioinformatics, University of Mississippi Medical Center</institution>
, Jackson, MS,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gudnason, V" sort="Gudnason, V" uniqKey="Gudnason V" first="V" last="Gudnason">V. Gudnason</name>
<affiliation wicri:level="1"><nlm:aff id="aff24"><institution>Icelandic Heart Association</institution>
, Kopavogur,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25"><institution>University of Iceland</institution>
, Reykjavik,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Harris, T B" sort="Harris, T B" uniqKey="Harris T" first="T B" last="Harris">T B Harris</name>
<affiliation wicri:level="1"><nlm:aff id="aff63"><institution>Intramural Research Program National Institutes on Aging, National Institutes of Health</institution>
, Bethesda, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Heiss, G" sort="Heiss, G" uniqKey="Heiss G" first="G" last="Heiss">G. Heiss</name>
<affiliation wicri:level="1"><nlm:aff id="aff64"><institution>Department of Epidemiology, University of North Carolina Gillings School of Global Public Health</institution>
, Chapel Hill, NC,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hofman, A" sort="Hofman, A" uniqKey="Hofman A" first="A" last="Hofman">A. Hofman</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Holliday, E G" sort="Holliday, E G" uniqKey="Holliday E" first="E G" last="Holliday">E G Holliday</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Huffman, J" sort="Huffman, J" uniqKey="Huffman J" first="J" last="Huffman">J. Huffman</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kardia, S L R" sort="Kardia, S L R" uniqKey="Kardia S" first="S L R" last="Kardia">S L R. Kardia</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>Department of Epidemiology, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kochan, N" sort="Kochan, N" uniqKey="Kochan N" first="N" last="Kochan">N. Kochan</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff65"><institution>Neuropsychiatric Institute, Prince of Wales Hospital</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Knopman, D S" sort="Knopman, D S" uniqKey="Knopman D" first="D S" last="Knopman">D S Knopman</name>
<affiliation wicri:level="1"><nlm:aff id="aff66"><institution>Department of Neurology, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kwok, J B" sort="Kwok, J B" uniqKey="Kwok J" first="J B" last="Kwok">J B Kwok</name>
<affiliation wicri:level="1"><nlm:aff id="aff67"><institution>Neuroscience Research Australia</institution>
, Randwick, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff68"><institution>School of Medical Sciences, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lambert, J C" sort="Lambert, J C" uniqKey="Lambert J" first="J-C" last="Lambert">J-C Lambert</name>
<affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique</institution>
, Lille,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lee, T" sort="Lee, T" uniqKey="Lee T" first="T" last="Lee">T. Lee</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff65"><institution>Neuropsychiatric Institute, Prince of Wales Hospital</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, G" sort="Li, G" uniqKey="Li G" first="G" last="Li">G. Li</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, S C" sort="Li, S C" uniqKey="Li S" first="S-C" last="Li">S-C Li</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff69"><institution>Technische Universität Dresden</institution>
, Dresden,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Loitfelder, M" sort="Loitfelder, M" uniqKey="Loitfelder M" first="M" last="Loitfelder">M. Loitfelder</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lopez, O L" sort="Lopez, O L" uniqKey="Lopez O" first="O L" last="Lopez">O L Lopez</name>
<affiliation wicri:level="1"><nlm:aff id="aff39"><institution>Department of Neurology, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lundervold, A J" sort="Lundervold, A J" uniqKey="Lundervold A" first="A J" last="Lundervold">A J Lundervold</name>
<affiliation wicri:level="1"><nlm:aff id="aff70"><institution>Department of Biological and Medical Psychology, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff71"><institution>Kavli Research Centre for Aging and Dementia, Haraldsplass Deaconess Hospital</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff72"><institution>K.G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lundqvist, A" sort="Lundqvist, A" uniqKey="Lundqvist A" first="A" last="Lundqvist">A. Lundqvist</name>
<affiliation wicri:level="1"><nlm:aff id="aff73"><institution>Umeå Center for Functional Brain Imaging (UFBI), Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mather, K A" sort="Mather, K A" uniqKey="Mather K" first="K A" last="Mather">K A Mather</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mirza, S S" sort="Mirza, S S" uniqKey="Mirza S" first="S S" last="Mirza">S S Mirza</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nyberg, L" sort="Nyberg, L" uniqKey="Nyberg L" first="L" last="Nyberg">L. Nyberg</name>
<affiliation wicri:level="1"><nlm:aff id="aff73"><institution>Umeå Center for Functional Brain Imaging (UFBI), Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff74"><institution>Department of Radiation Sciences, Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff75"><institution>Department of Integrative Medical Biology, Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Oostra, B A" sort="Oostra, B A" uniqKey="Oostra B" first="B A" last="Oostra">B A Oostra</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Palotie, A" sort="Palotie, A" uniqKey="Palotie A" first="A" last="Palotie">A. Palotie</name>
<affiliation wicri:level="1"><nlm:aff id="aff76"><institution>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff77"><institution>Institute for Molecular Medicine Finland (FIMM), University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff78"><institution>Department of Medical Genetics, University of Helsinki and University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Papenberg, G" sort="Papenberg, G" uniqKey="Papenberg G" first="G" last="Papenberg">G. Papenberg</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff79"><institution>Karolinska Institutet, Aging Research Center, Stockholm University</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pattie, A" sort="Pattie, A" uniqKey="Pattie A" first="A" last="Pattie">A. Pattie</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Petrovic, K" sort="Petrovic, K" uniqKey="Petrovic K" first="K" last="Petrovic">K. Petrovic</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Polasek, O" sort="Polasek, O" uniqKey="Polasek O" first="O" last="Polasek">O. Polasek</name>
<affiliation wicri:level="1"><nlm:aff id="aff80"><institution>Faculty of Medicine, Department of Public Health, University of Split</institution>
, Split,<country>Croatia</country>
</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Psaty, B M" sort="Psaty, B M" uniqKey="Psaty B" first="B M" last="Psaty">B M Psaty</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff81"><institution>Deparment of Epidemiology, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff82"><institution>Deparment of Health Services, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff83"><institution>Group Health Research Unit, Group Health Cooperative</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Redmond, P" sort="Redmond, P" uniqKey="Redmond P" first="P" last="Redmond">P. Redmond</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Reppermund, S" sort="Reppermund, S" uniqKey="Reppermund S" first="S" last="Reppermund">S. Reppermund</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rotter, J I" sort="Rotter, J I" uniqKey="Rotter J" first="J I" last="Rotter">J I Rotter</name>
<affiliation wicri:level="1"><nlm:aff id="aff84"><institution>Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff85"><institution>Division of Genetic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schmidt, H" sort="Schmidt, H" uniqKey="Schmidt H" first="H" last="Schmidt">H. Schmidt</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff86"><institution>Centre for Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schuur, M" sort="Schuur, M" uniqKey="Schuur M" first="M" last="Schuur">M. Schuur</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Neurology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schofield, P W" sort="Schofield, P W" uniqKey="Schofield P" first="P W" last="Schofield">P W Schofield</name>
<affiliation wicri:level="1"><nlm:aff id="aff87"><institution>School of Medicine and Public Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Scott, R J" sort="Scott, R J" uniqKey="Scott R" first="R J" last="Scott">R J Scott</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Steen, V M" sort="Steen, V M" uniqKey="Steen V" first="V M" last="Steen">V M Steen</name>
<affiliation wicri:level="1"><nlm:aff id="aff8"><institution>K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff9"><institution>Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stott, D J" sort="Stott, D J" uniqKey="Stott D" first="D J" last="Stott">D J Stott</name>
<affiliation wicri:level="1"><nlm:aff id="aff88"><institution>Institute of Cardiovascular and Medical Sciences, University of Glasgow</institution>
, Glasgow,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Swieten, J C" sort="Van Swieten, J C" uniqKey="Van Swieten J" first="J C" last="Van Swieten">J C Van Swieten</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Neurology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Taylor, K D" sort="Taylor, K D" uniqKey="Taylor K" first="K D" last="Taylor">K D Taylor</name>
<affiliation wicri:level="1"><nlm:aff id="aff84"><institution>Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff89"><institution>Department of Pediatrics, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Trollor, J" sort="Trollor, J" uniqKey="Trollor J" first="J" last="Trollor">J. Trollor</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff90"><institution>Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Trompet, S" sort="Trompet, S" uniqKey="Trompet S" first="S" last="Trompet">S. Trompet</name>
<affiliation wicri:level="1"><nlm:aff id="aff22"><institution>Department of Gerontology and Geriatrics, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Department of Cardiology, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Uitterlinden, A G" sort="Uitterlinden, A G" uniqKey="Uitterlinden A" first="A G" last="Uitterlinden">A G Uitterlinden</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff92"><institution>Department of Internal Medicine, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Weinstein, G" sort="Weinstein, G" uniqKey="Weinstein G" first="G" last="Weinstein">G. Weinstein</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Widen, E" sort="Widen, E" uniqKey="Widen E" first="E" last="Widen">E. Widen</name>
<affiliation wicri:level="1"><nlm:aff id="aff77"><institution>Institute for Molecular Medicine Finland (FIMM), University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Windham, B G" sort="Windham, B G" uniqKey="Windham B" first="B G" last="Windham">B G Windham</name>
<affiliation wicri:level="1"><nlm:aff id="aff93"><institution>Division of Geriatrics, Department of Medicine, University of Mississippi Medical Center</institution>
, Jackson, MS,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jukema, J W" sort="Jukema, J W" uniqKey="Jukema J" first="J W" last="Jukema">J W Jukema</name>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Department of Cardiology, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff94"><institution>Durrer Center for Cardiogenetic Research</institution>
, Amsterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff95"><institution>Interuniversity Cardiology Institute of the Netherlands</institution>
, Utrecht,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wright, A F" sort="Wright, A F" uniqKey="Wright A" first="A F" last="Wright">A F Wright</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wright, M J" sort="Wright, M J" uniqKey="Wright M" first="M J" last="Wright">M J Wright</name>
<affiliation wicri:level="1"><nlm:aff id="aff96"><institution>Neuroimaging Genetics Group, QIMR Berghofer Medical Research Institute</institution>
, Brisbane, QLD,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yang, Q" sort="Yang, Q" uniqKey="Yang Q" first="Q" last="Yang">Q. Yang</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff31"><institution>Department of Biostatistics, Boston University School of Public Health</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amieva, H" sort="Amieva, H" uniqKey="Amieva H" first="H" last="Amieva">H. Amieva</name>
<affiliation wicri:level="1"><nlm:aff id="aff52"><institution>Inserm U897, Université Bordeaux Segalen</institution>
, Bordeaux,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Attia, J R" sort="Attia, J R" uniqKey="Attia J" first="J R" last="Attia">J R Attia</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bennett, D A" sort="Bennett, D A" uniqKey="Bennett D" first="D A" last="Bennett">D A Bennett</name>
<affiliation wicri:level="1"><nlm:aff id="aff32"><institution>Rush Alzheimer's Disease Center, Rush University Medical Center</institution>
, Chicago, IL,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brodaty, H" sort="Brodaty, H" uniqKey="Brodaty H" first="H" last="Brodaty">H. Brodaty</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff97"><institution>Dementia Collaborative Research Centre, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Craen, A J M" sort="De Craen, A J M" uniqKey="De Craen A" first="A J M" last="De Craen">A J M. De Craen</name>
<affiliation wicri:level="1"><nlm:aff id="aff22"><institution>Department of Gerontology and Geriatrics, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff23"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hayward, C" sort="Hayward, C" uniqKey="Hayward C" first="C" last="Hayward">C. Hayward</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ikram, M A" sort="Ikram, M A" uniqKey="Ikram M" first="M A" last="Ikram">M A Ikram</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Neurology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff98"><institution>Department of Radiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lindenberger, U" sort="Lindenberger, U" uniqKey="Lindenberger U" first="U" last="Lindenberger">U. Lindenberger</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nilsson, L G" sort="Nilsson, L G" uniqKey="Nilsson L" first="L-G" last="Nilsson">L-G Nilsson</name>
<affiliation wicri:level="1"><nlm:aff id="aff99"><institution>ARC, Karolinska Institutet, Stockholm and UFBI, Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Porteous, D J" sort="Porteous, D J" uniqKey="Porteous D" first="D J" last="Porteous">D J Porteous</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff60"><institution>Generation Scotland, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="R Ikkonen, K" sort="R Ikkonen, K" uniqKey="R Ikkonen K" first="K" last="R Ikkönen">K. R Ikkönen</name>
<affiliation wicri:level="1"><nlm:aff id="aff15"><institution>Institute of Behavioural Sciences, University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Reinvang, I" sort="Reinvang, I" uniqKey="Reinvang I" first="I" last="Reinvang">I. Reinvang</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Psychology, University of Oslo</institution>
, Oslo,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rudan, I" sort="Rudan, I" uniqKey="Rudan I" first="I" last="Rudan">I. Rudan</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Centre for Population Health Sciences, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sachdev, P S" sort="Sachdev, P S" uniqKey="Sachdev P" first="P S" last="Sachdev">P S Sachdev</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff65"><institution>Neuropsychiatric Institute, Prince of Wales Hospital</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schmidt, R" sort="Schmidt, R" uniqKey="Schmidt R" first="R" last="Schmidt">R. Schmidt</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schofield, P R" sort="Schofield, P R" uniqKey="Schofield P" first="P R" last="Schofield">P R Schofield</name>
<affiliation wicri:level="1"><nlm:aff id="aff100"><institution>Neuroscience Research Australia</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff101"><institution>Faculty of Medicine, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Srikanth, V" sort="Srikanth, V" uniqKey="Srikanth V" first="V" last="Srikanth">V. Srikanth</name>
<affiliation><nlm:aff id="aff28"><institution>Menzies Research Institute</institution>
, Hobart,<country>Tasmania</country>
</nlm:aff>
<wicri:noCountry code="nlm country">Tasmania</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff102"><institution>Stroke and Ageing Research, Medicine, Southern Clinical School, Monash University</institution>
, Melbourne, VIC,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Starr, J M" sort="Starr, J M" uniqKey="Starr J" first="J M" last="Starr">J M Starr</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff103"><institution>Alzheimer Scotland Dementia Research Centre, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Turner, S T" sort="Turner, S T" uniqKey="Turner S" first="S T" last="Turner">S T Turner</name>
<affiliation wicri:level="1"><nlm:aff id="aff104"><institution>Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Weir, D R" sort="Weir, D R" uniqKey="Weir D" first="D R" last="Weir">D R Weir</name>
<affiliation wicri:level="1"><nlm:aff id="aff58"><institution>Survey Research Center, Institute for Social Research, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wilson, J F" sort="Wilson, J F" uniqKey="Wilson J" first="J F" last="Wilson">J F Wilson</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Centre for Population Health Sciences, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Duijn, C" sort="Van Duijn, C" uniqKey="Van Duijn C" first="C" last="Van Duijn">C. Van Duijn</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Launer, L" sort="Launer, L" uniqKey="Launer L" first="L" last="Launer">L. Launer</name>
<affiliation wicri:level="1"><nlm:aff id="aff63"><institution>Intramural Research Program National Institutes on Aging, National Institutes of Health</institution>
, Bethesda, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fitzpatrick, A L" sort="Fitzpatrick, A L" uniqKey="Fitzpatrick A" first="A L" last="Fitzpatrick">A L Fitzpatrick</name>
<affiliation wicri:level="1"><nlm:aff id="aff81"><institution>Deparment of Epidemiology, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff105"><institution>Department of Global Health, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Seshadri, S" sort="Seshadri, S" uniqKey="Seshadri S" first="S" last="Seshadri">S. Seshadri</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mosley, T H" sort="Mosley, T H" uniqKey="Mosley T" first="T H" last="Mosley">T H Mosley</name>
<affiliation wicri:level="1"><nlm:aff id="aff93"><institution>Division of Geriatrics, Department of Medicine, University of Mississippi Medical Center</institution>
, Jackson, MS,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Deary, I J" sort="Deary, I J" uniqKey="Deary I" first="I J" last="Deary">I J Deary</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">25644384</idno>
<idno type="pmc">4356746</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356746</idno>
<idno type="RBID">PMC:4356746</idno>
<idno type="doi">10.1038/mp.2014.188</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">000031</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000031</idno>
<idno type="wicri:Area/Pmc/Curation">000031</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000031</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000F78</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000F78</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (<italic>N</italic>
=53 949)</title>
<author><name sortKey="Davies, G" sort="Davies, G" uniqKey="Davies G" first="G" last="Davies">G. Davies</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Armstrong, N" sort="Armstrong, N" uniqKey="Armstrong N" first="N" last="Armstrong">N. Armstrong</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>School of Mathematics and Statistics, University of Sydney</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bis, J C" sort="Bis, J C" uniqKey="Bis J" first="J C" last="Bis">J C Bis</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bressler, J" sort="Bressler, J" uniqKey="Bressler J" first="J" last="Bressler">J. Bressler</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston</institution>
, Houston, TX,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chouraki, V" sort="Chouraki, V" uniqKey="Chouraki V" first="V" last="Chouraki">V. Chouraki</name>
<affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique</institution>
, Lille,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Giddaluru, S" sort="Giddaluru, S" uniqKey="Giddaluru S" first="S" last="Giddaluru">S. Giddaluru</name>
<affiliation wicri:level="1"><nlm:aff id="aff8"><institution>K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff9"><institution>Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hofer, E" sort="Hofer, E" uniqKey="Hofer E" first="E" last="Hofer">E. Hofer</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff11"><institution>Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ibrahim Verbaas, C A" sort="Ibrahim Verbaas, C A" uniqKey="Ibrahim Verbaas C" first="C A" last="Ibrahim-Verbaas">C A Ibrahim-Verbaas</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Neurology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kirin, M" sort="Kirin, M" uniqKey="Kirin M" first="M" last="Kirin">M. Kirin</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Centre for Population Health Sciences, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lahti, J" sort="Lahti, J" uniqKey="Lahti J" first="J" last="Lahti">J. Lahti</name>
<affiliation wicri:level="1"><nlm:aff id="aff15"><institution>Institute of Behavioural Sciences, University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff16"><institution>Folkhälsan Research Centre</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Der Lee, S J" sort="Van Der Lee, S J" uniqKey="Van Der Lee S" first="S J" last="Van Der Lee">S J Van Der Lee</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Le Hellard, S" sort="Le Hellard, S" uniqKey="Le Hellard S" first="S" last="Le Hellard">S. Le Hellard</name>
<affiliation wicri:level="1"><nlm:aff id="aff8"><institution>K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff9"><institution>Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Liu, T" sort="Liu, T" uniqKey="Liu T" first="T" last="Liu">T. Liu</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff18"><institution>Max Planck Institute for Molecular Genetics</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Marioni, R E" sort="Marioni, R E" uniqKey="Marioni R" first="R E" last="Marioni">R E Marioni</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff20"><institution>Queensland Brain Institute, The University of Queensland</institution>
, Brisbane, QLD,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Oldmeadow, C" sort="Oldmeadow, C" uniqKey="Oldmeadow C" first="C" last="Oldmeadow">C. Oldmeadow</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Postmus, I" sort="Postmus, I" uniqKey="Postmus I" first="I" last="Postmus">I. Postmus</name>
<affiliation wicri:level="1"><nlm:aff id="aff22"><institution>Department of Gerontology and Geriatrics, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff23"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Smith, A V" sort="Smith, A V" uniqKey="Smith A" first="A V" last="Smith">A V Smith</name>
<affiliation wicri:level="1"><nlm:aff id="aff24"><institution>Icelandic Heart Association</institution>
, Kopavogur,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25"><institution>University of Iceland</institution>
, Reykjavik,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Smith, J A" sort="Smith, J A" uniqKey="Smith J" first="J A" last="Smith">J A Smith</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>Department of Epidemiology, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Thalamuthu, A" sort="Thalamuthu, A" uniqKey="Thalamuthu A" first="A" last="Thalamuthu">A. Thalamuthu</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Thomson, R" sort="Thomson, R" uniqKey="Thomson R" first="R" last="Thomson">R. Thomson</name>
<affiliation><nlm:aff id="aff28"><institution>Menzies Research Institute</institution>
, Hobart,<country>Tasmania</country>
</nlm:aff>
<wicri:noCountry code="nlm country">Tasmania</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Vitart, V" sort="Vitart, V" uniqKey="Vitart V" first="V" last="Vitart">V. Vitart</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, J" sort="Wang, J" uniqKey="Wang J" first="J" last="Wang">J. Wang</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff31"><institution>Department of Biostatistics, Boston University School of Public Health</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yu, L" sort="Yu, L" uniqKey="Yu L" first="L" last="Yu">L. Yu</name>
<affiliation wicri:level="1"><nlm:aff id="aff32"><institution>Rush Alzheimer's Disease Center, Rush University Medical Center</institution>
, Chicago, IL,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zgaga, L" sort="Zgaga, L" uniqKey="Zgaga L" first="L" last="Zgaga">L. Zgaga</name>
<affiliation wicri:level="1"><nlm:aff id="aff33"><institution>Department of Public Health and Primary Care, Trinity College Dublin</institution>
, Dublin,<country>Ireland</country>
</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff34"><institution>Andrija Stampar School of Public Health, Medical School, University of Zagreb</institution>
, Zagreb,<country>Croatia</country>
</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zhao, W" sort="Zhao, W" uniqKey="Zhao W" first="W" last="Zhao">W. Zhao</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>Department of Epidemiology, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boxall, R" sort="Boxall, R" uniqKey="Boxall R" first="R" last="Boxall">R. Boxall</name>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Harris, S E" sort="Harris, S E" uniqKey="Harris S" first="S E" last="Harris">S E Harris</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hill, W D" sort="Hill, W D" uniqKey="Hill W" first="W D" last="Hill">W D Hill</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Liewald, D C" sort="Liewald, D C" uniqKey="Liewald D" first="D C" last="Liewald">D C Liewald</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Luciano, M" sort="Luciano, M" uniqKey="Luciano M" first="M" last="Luciano">M. Luciano</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Adams, H" sort="Adams, H" uniqKey="Adams H" first="H" last="Adams">H. Adams</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ames, D" sort="Ames, D" uniqKey="Ames D" first="D" last="Ames">D. Ames</name>
<affiliation wicri:level="1"><nlm:aff id="aff37"><institution>National Ageing Research Institute, Royal Melbourne Hospital</institution>
, Melbourne, VIC,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff38"><institution>Academic Unit for Psychiatry of Old Age, St George's Hospital, University of Melbourne</institution>
, Kew,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amin, N" sort="Amin, N" uniqKey="Amin N" first="N" last="Amin">N. Amin</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amouyel, P" sort="Amouyel, P" uniqKey="Amouyel P" first="P" last="Amouyel">P. Amouyel</name>
<affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique</institution>
, Lille,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Assareh, A A" sort="Assareh, A A" uniqKey="Assareh A" first="A A" last="Assareh">A A Assareh</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Au, R" sort="Au, R" uniqKey="Au R" first="R" last="Au">R. Au</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Becker, J T" sort="Becker, J T" uniqKey="Becker J" first="J T" last="Becker">J T Becker</name>
<affiliation wicri:level="1"><nlm:aff id="aff39"><institution>Department of Neurology, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff40"><institution>Department of Psychiatry, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff41"><institution>Department of Psychology, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Beiser, A" sort="Beiser, A" uniqKey="Beiser A" first="A" last="Beiser">A. Beiser</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Berr, C" sort="Berr, C" uniqKey="Berr C" first="C" last="Berr">C. Berr</name>
<affiliation wicri:level="1"><nlm:aff id="aff42"><institution>Inserm, U106</institution>
, Montpellier,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff43"><institution>Université Montpellier I</institution>
, Montpellier,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bertram, L" sort="Bertram, L" uniqKey="Bertram L" first="L" last="Bertram">L. Bertram</name>
<affiliation wicri:level="1"><nlm:aff id="aff18"><institution>Max Planck Institute for Molecular Genetics</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff44"><institution>Faculty of Medicine, School of Public Health, Imperial College</institution>
, London,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Boerwinkle, E" sort="Boerwinkle, E" uniqKey="Boerwinkle E" first="E" last="Boerwinkle">E. Boerwinkle</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston</institution>
, Houston, TX,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff45"><institution>Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas Health Science Center at Houston</institution>
, Houston, TX,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff46"><institution>Human Genome Sequencing Center, Baylor College of Medicine</institution>
, Houston, TX,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Buckley, B M" sort="Buckley, B M" uniqKey="Buckley B" first="B M" last="Buckley">B M Buckley</name>
<affiliation wicri:level="1"><nlm:aff id="aff47"><institution>Department of Pharmacology and Therapeutics, University College Cork</institution>
, Cork,<country>Ireland</country>
</nlm:aff>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Campbell, H" sort="Campbell, H" uniqKey="Campbell H" first="H" last="Campbell">H. Campbell</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Centre for Population Health Sciences, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Corley, J" sort="Corley, J" uniqKey="Corley J" first="J" last="Corley">J. Corley</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Jager, P L" sort="De Jager, P L" uniqKey="De Jager P" first="P L" last="De Jager">P L De Jager</name>
<affiliation wicri:level="1"><nlm:aff id="aff48"><institution>Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff49"><institution>Harvard Medical School</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff50"><institution>Program in Medical and Population Genetics, Broad Institute</institution>
, Cambridge, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Dufouil, C" sort="Dufouil, C" uniqKey="Dufouil C" first="C" last="Dufouil">C. Dufouil</name>
<affiliation wicri:level="1"><nlm:aff id="aff51"><institution>Inserm U708, Neuroepidemiology</institution>
, Paris,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff52"><institution>Inserm U897, Université Bordeaux Segalen</institution>
, Bordeaux,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Eriksson, J G" sort="Eriksson, J G" uniqKey="Eriksson J" first="J G" last="Eriksson">J G Eriksson</name>
<affiliation wicri:level="1"><nlm:aff id="aff16"><institution>Folkhälsan Research Centre</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff53"><institution>National Institute for Health and Welfare</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff54"><institution>Department of General Practice and Primary health Care, University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff55"><institution>Unit of General Practice, Helsinki University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Espeseth, T" sort="Espeseth, T" uniqKey="Espeseth T" first="T" last="Espeseth">T. Espeseth</name>
<affiliation wicri:level="1"><nlm:aff id="aff56"><institution>K.G. Jebsen Centre for Psychosis Research, Norwegian Centre For Mental Disorders Research (NORMENT), Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo</institution>
, Oslo,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Psychology, University of Oslo</institution>
, Oslo,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Faul, J D" sort="Faul, J D" uniqKey="Faul J" first="J D" last="Faul">J D Faul</name>
<affiliation wicri:level="1"><nlm:aff id="aff58"><institution>Survey Research Center, Institute for Social Research, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ford, I" sort="Ford, I" uniqKey="Ford I" first="I" last="Ford">I. Ford</name>
<affiliation wicri:level="1"><nlm:aff id="aff59"><institution>Robertson Center for Biostatistics</institution>
, Glasgow,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Scotland, Generation" sort="Scotland, Generation" uniqKey="Scotland G" first="Generation" last="Scotland">Generation Scotland</name>
<affiliation wicri:level="1"><nlm:aff id="aff60"><institution>Generation Scotland, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gottesman, R F" sort="Gottesman, R F" uniqKey="Gottesman R" first="R F" last="Gottesman">R F Gottesman</name>
<affiliation wicri:level="1"><nlm:aff id="aff61"><institution>Department of Neurology, Johns Hopkins University School of Medicine</institution>
, Baltimore, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Griswold, M E" sort="Griswold, M E" uniqKey="Griswold M" first="M E" last="Griswold">M E Griswold</name>
<affiliation wicri:level="1"><nlm:aff id="aff62"><institution>Center of Biostatistics and Bioinformatics, University of Mississippi Medical Center</institution>
, Jackson, MS,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gudnason, V" sort="Gudnason, V" uniqKey="Gudnason V" first="V" last="Gudnason">V. Gudnason</name>
<affiliation wicri:level="1"><nlm:aff id="aff24"><institution>Icelandic Heart Association</institution>
, Kopavogur,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff25"><institution>University of Iceland</institution>
, Reykjavik,<country>Iceland</country>
</nlm:aff>
<country xml:lang="fr">Islande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Harris, T B" sort="Harris, T B" uniqKey="Harris T" first="T B" last="Harris">T B Harris</name>
<affiliation wicri:level="1"><nlm:aff id="aff63"><institution>Intramural Research Program National Institutes on Aging, National Institutes of Health</institution>
, Bethesda, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Heiss, G" sort="Heiss, G" uniqKey="Heiss G" first="G" last="Heiss">G. Heiss</name>
<affiliation wicri:level="1"><nlm:aff id="aff64"><institution>Department of Epidemiology, University of North Carolina Gillings School of Global Public Health</institution>
, Chapel Hill, NC,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hofman, A" sort="Hofman, A" uniqKey="Hofman A" first="A" last="Hofman">A. Hofman</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Holliday, E G" sort="Holliday, E G" uniqKey="Holliday E" first="E G" last="Holliday">E G Holliday</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Huffman, J" sort="Huffman, J" uniqKey="Huffman J" first="J" last="Huffman">J. Huffman</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kardia, S L R" sort="Kardia, S L R" uniqKey="Kardia S" first="S L R" last="Kardia">S L R. Kardia</name>
<affiliation wicri:level="1"><nlm:aff id="aff26"><institution>Department of Epidemiology, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kochan, N" sort="Kochan, N" uniqKey="Kochan N" first="N" last="Kochan">N. Kochan</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff65"><institution>Neuropsychiatric Institute, Prince of Wales Hospital</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Knopman, D S" sort="Knopman, D S" uniqKey="Knopman D" first="D S" last="Knopman">D S Knopman</name>
<affiliation wicri:level="1"><nlm:aff id="aff66"><institution>Department of Neurology, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kwok, J B" sort="Kwok, J B" uniqKey="Kwok J" first="J B" last="Kwok">J B Kwok</name>
<affiliation wicri:level="1"><nlm:aff id="aff67"><institution>Neuroscience Research Australia</institution>
, Randwick, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff68"><institution>School of Medical Sciences, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lambert, J C" sort="Lambert, J C" uniqKey="Lambert J" first="J-C" last="Lambert">J-C Lambert</name>
<affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique</institution>
, Lille,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lee, T" sort="Lee, T" uniqKey="Lee T" first="T" last="Lee">T. Lee</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff65"><institution>Neuropsychiatric Institute, Prince of Wales Hospital</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, G" sort="Li, G" uniqKey="Li G" first="G" last="Li">G. Li</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, S C" sort="Li, S C" uniqKey="Li S" first="S-C" last="Li">S-C Li</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff69"><institution>Technische Universität Dresden</institution>
, Dresden,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Loitfelder, M" sort="Loitfelder, M" uniqKey="Loitfelder M" first="M" last="Loitfelder">M. Loitfelder</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lopez, O L" sort="Lopez, O L" uniqKey="Lopez O" first="O L" last="Lopez">O L Lopez</name>
<affiliation wicri:level="1"><nlm:aff id="aff39"><institution>Department of Neurology, University of Pittsburgh</institution>
, Pittsburgh, PA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lundervold, A J" sort="Lundervold, A J" uniqKey="Lundervold A" first="A J" last="Lundervold">A J Lundervold</name>
<affiliation wicri:level="1"><nlm:aff id="aff70"><institution>Department of Biological and Medical Psychology, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff71"><institution>Kavli Research Centre for Aging and Dementia, Haraldsplass Deaconess Hospital</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff72"><institution>K.G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lundqvist, A" sort="Lundqvist, A" uniqKey="Lundqvist A" first="A" last="Lundqvist">A. Lundqvist</name>
<affiliation wicri:level="1"><nlm:aff id="aff73"><institution>Umeå Center for Functional Brain Imaging (UFBI), Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mather, K A" sort="Mather, K A" uniqKey="Mather K" first="K A" last="Mather">K A Mather</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mirza, S S" sort="Mirza, S S" uniqKey="Mirza S" first="S S" last="Mirza">S S Mirza</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nyberg, L" sort="Nyberg, L" uniqKey="Nyberg L" first="L" last="Nyberg">L. Nyberg</name>
<affiliation wicri:level="1"><nlm:aff id="aff73"><institution>Umeå Center for Functional Brain Imaging (UFBI), Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff74"><institution>Department of Radiation Sciences, Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff75"><institution>Department of Integrative Medical Biology, Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Oostra, B A" sort="Oostra, B A" uniqKey="Oostra B" first="B A" last="Oostra">B A Oostra</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Palotie, A" sort="Palotie, A" uniqKey="Palotie A" first="A" last="Palotie">A. Palotie</name>
<affiliation wicri:level="1"><nlm:aff id="aff76"><institution>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus</institution>
, Cambridge,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff77"><institution>Institute for Molecular Medicine Finland (FIMM), University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff78"><institution>Department of Medical Genetics, University of Helsinki and University Central Hospital</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Papenberg, G" sort="Papenberg, G" uniqKey="Papenberg G" first="G" last="Papenberg">G. Papenberg</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff79"><institution>Karolinska Institutet, Aging Research Center, Stockholm University</institution>
, Stockholm,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pattie, A" sort="Pattie, A" uniqKey="Pattie A" first="A" last="Pattie">A. Pattie</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Petrovic, K" sort="Petrovic, K" uniqKey="Petrovic K" first="K" last="Petrovic">K. Petrovic</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Polasek, O" sort="Polasek, O" uniqKey="Polasek O" first="O" last="Polasek">O. Polasek</name>
<affiliation wicri:level="1"><nlm:aff id="aff80"><institution>Faculty of Medicine, Department of Public Health, University of Split</institution>
, Split,<country>Croatia</country>
</nlm:aff>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Psaty, B M" sort="Psaty, B M" uniqKey="Psaty B" first="B M" last="Psaty">B M Psaty</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff81"><institution>Deparment of Epidemiology, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff82"><institution>Deparment of Health Services, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff83"><institution>Group Health Research Unit, Group Health Cooperative</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Redmond, P" sort="Redmond, P" uniqKey="Redmond P" first="P" last="Redmond">P. Redmond</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Reppermund, S" sort="Reppermund, S" uniqKey="Reppermund S" first="S" last="Reppermund">S. Reppermund</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rotter, J I" sort="Rotter, J I" uniqKey="Rotter J" first="J I" last="Rotter">J I Rotter</name>
<affiliation wicri:level="1"><nlm:aff id="aff84"><institution>Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff85"><institution>Division of Genetic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schmidt, H" sort="Schmidt, H" uniqKey="Schmidt H" first="H" last="Schmidt">H. Schmidt</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff86"><institution>Centre for Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schuur, M" sort="Schuur, M" uniqKey="Schuur M" first="M" last="Schuur">M. Schuur</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Neurology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schofield, P W" sort="Schofield, P W" uniqKey="Schofield P" first="P W" last="Schofield">P W Schofield</name>
<affiliation wicri:level="1"><nlm:aff id="aff87"><institution>School of Medicine and Public Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Scott, R J" sort="Scott, R J" uniqKey="Scott R" first="R J" last="Scott">R J Scott</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Steen, V M" sort="Steen, V M" uniqKey="Steen V" first="V M" last="Steen">V M Steen</name>
<affiliation wicri:level="1"><nlm:aff id="aff8"><institution>K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff9"><institution>Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital</institution>
, Bergen,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Stott, D J" sort="Stott, D J" uniqKey="Stott D" first="D J" last="Stott">D J Stott</name>
<affiliation wicri:level="1"><nlm:aff id="aff88"><institution>Institute of Cardiovascular and Medical Sciences, University of Glasgow</institution>
, Glasgow,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Swieten, J C" sort="Van Swieten, J C" uniqKey="Van Swieten J" first="J C" last="Van Swieten">J C Van Swieten</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Neurology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Taylor, K D" sort="Taylor, K D" uniqKey="Taylor K" first="K D" last="Taylor">K D Taylor</name>
<affiliation wicri:level="1"><nlm:aff id="aff84"><institution>Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff89"><institution>Department of Pediatrics, Harbor-UCLA Medical Center</institution>
, Los Angeles, CA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Trollor, J" sort="Trollor, J" uniqKey="Trollor J" first="J" last="Trollor">J. Trollor</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff90"><institution>Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Trompet, S" sort="Trompet, S" uniqKey="Trompet S" first="S" last="Trompet">S. Trompet</name>
<affiliation wicri:level="1"><nlm:aff id="aff22"><institution>Department of Gerontology and Geriatrics, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Department of Cardiology, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Uitterlinden, A G" sort="Uitterlinden, A G" uniqKey="Uitterlinden A" first="A G" last="Uitterlinden">A G Uitterlinden</name>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff92"><institution>Department of Internal Medicine, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Weinstein, G" sort="Weinstein, G" uniqKey="Weinstein G" first="G" last="Weinstein">G. Weinstein</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Widen, E" sort="Widen, E" uniqKey="Widen E" first="E" last="Widen">E. Widen</name>
<affiliation wicri:level="1"><nlm:aff id="aff77"><institution>Institute for Molecular Medicine Finland (FIMM), University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Windham, B G" sort="Windham, B G" uniqKey="Windham B" first="B G" last="Windham">B G Windham</name>
<affiliation wicri:level="1"><nlm:aff id="aff93"><institution>Division of Geriatrics, Department of Medicine, University of Mississippi Medical Center</institution>
, Jackson, MS,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Jukema, J W" sort="Jukema, J W" uniqKey="Jukema J" first="J W" last="Jukema">J W Jukema</name>
<affiliation wicri:level="1"><nlm:aff id="aff91"><institution>Department of Cardiology, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff94"><institution>Durrer Center for Cardiogenetic Research</institution>
, Amsterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff95"><institution>Interuniversity Cardiology Institute of the Netherlands</institution>
, Utrecht,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wright, A F" sort="Wright, A F" uniqKey="Wright A" first="A F" last="Wright">A F Wright</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wright, M J" sort="Wright, M J" uniqKey="Wright M" first="M J" last="Wright">M J Wright</name>
<affiliation wicri:level="1"><nlm:aff id="aff96"><institution>Neuroimaging Genetics Group, QIMR Berghofer Medical Research Institute</institution>
, Brisbane, QLD,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yang, Q" sort="Yang, Q" uniqKey="Yang Q" first="Q" last="Yang">Q. Yang</name>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff31"><institution>Department of Biostatistics, Boston University School of Public Health</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Amieva, H" sort="Amieva, H" uniqKey="Amieva H" first="H" last="Amieva">H. Amieva</name>
<affiliation wicri:level="1"><nlm:aff id="aff52"><institution>Inserm U897, Université Bordeaux Segalen</institution>
, Bordeaux,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Attia, J R" sort="Attia, J R" uniqKey="Attia J" first="J R" last="Attia">J R Attia</name>
<affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Hunter Medical Research Institute and Faculty of Health, University of Newcastle</institution>
, Newcastle, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bennett, D A" sort="Bennett, D A" uniqKey="Bennett D" first="D A" last="Bennett">D A Bennett</name>
<affiliation wicri:level="1"><nlm:aff id="aff32"><institution>Rush Alzheimer's Disease Center, Rush University Medical Center</institution>
, Chicago, IL,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brodaty, H" sort="Brodaty, H" uniqKey="Brodaty H" first="H" last="Brodaty">H. Brodaty</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff97"><institution>Dementia Collaborative Research Centre, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="De Craen, A J M" sort="De Craen, A J M" uniqKey="De Craen A" first="A J M" last="De Craen">A J M. De Craen</name>
<affiliation wicri:level="1"><nlm:aff id="aff22"><institution>Department of Gerontology and Geriatrics, Leiden University Medical Center</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff23"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hayward, C" sort="Hayward, C" uniqKey="Hayward C" first="C" last="Hayward">C. Hayward</name>
<affiliation wicri:level="1"><nlm:aff id="aff29"><institution>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ikram, M A" sort="Ikram, M A" uniqKey="Ikram M" first="M A" last="Ikram">M A Ikram</name>
<affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Neurology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff98"><institution>Department of Radiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lindenberger, U" sort="Lindenberger, U" uniqKey="Lindenberger U" first="U" last="Lindenberger">U. Lindenberger</name>
<affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Max Planck Institute for Human Development</institution>
, Berlin,<country>Germany</country>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nilsson, L G" sort="Nilsson, L G" uniqKey="Nilsson L" first="L-G" last="Nilsson">L-G Nilsson</name>
<affiliation wicri:level="1"><nlm:aff id="aff99"><institution>ARC, Karolinska Institutet, Stockholm and UFBI, Umeå University</institution>
, Umeå,<country>Sweden</country>
</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Porteous, D J" sort="Porteous, D J" uniqKey="Porteous D" first="D J" last="Porteous">D J Porteous</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff19"><institution>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff60"><institution>Generation Scotland, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="R Ikkonen, K" sort="R Ikkonen, K" uniqKey="R Ikkonen K" first="K" last="R Ikkönen">K. R Ikkönen</name>
<affiliation wicri:level="1"><nlm:aff id="aff15"><institution>Institute of Behavioural Sciences, University of Helsinki</institution>
, Helsinki,<country>Finland</country>
</nlm:aff>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Reinvang, I" sort="Reinvang, I" uniqKey="Reinvang I" first="I" last="Reinvang">I. Reinvang</name>
<affiliation wicri:level="1"><nlm:aff id="aff57"><institution>Department of Psychology, University of Oslo</institution>
, Oslo,<country>Norway</country>
</nlm:aff>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rudan, I" sort="Rudan, I" uniqKey="Rudan I" first="I" last="Rudan">I. Rudan</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Centre for Population Health Sciences, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sachdev, P S" sort="Sachdev, P S" uniqKey="Sachdev P" first="P S" last="Sachdev">P S Sachdev</name>
<affiliation wicri:level="1"><nlm:aff id="aff27"><institution>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff65"><institution>Neuropsychiatric Institute, Prince of Wales Hospital</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schmidt, R" sort="Schmidt, R" uniqKey="Schmidt R" first="R" last="Schmidt">R. Schmidt</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Department of Neurology, Medical University of Graz</institution>
, Graz,<country>Austria</country>
</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Schofield, P R" sort="Schofield, P R" uniqKey="Schofield P" first="P R" last="Schofield">P R Schofield</name>
<affiliation wicri:level="1"><nlm:aff id="aff100"><institution>Neuroscience Research Australia</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff101"><institution>Faculty of Medicine, University of New South Wales</institution>
, Sydney, NSW,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Srikanth, V" sort="Srikanth, V" uniqKey="Srikanth V" first="V" last="Srikanth">V. Srikanth</name>
<affiliation><nlm:aff id="aff28"><institution>Menzies Research Institute</institution>
, Hobart,<country>Tasmania</country>
</nlm:aff>
<wicri:noCountry code="nlm country">Tasmania</wicri:noCountry>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff102"><institution>Stroke and Ageing Research, Medicine, Southern Clinical School, Monash University</institution>
, Melbourne, VIC,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Starr, J M" sort="Starr, J M" uniqKey="Starr J" first="J M" last="Starr">J M Starr</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff103"><institution>Alzheimer Scotland Dementia Research Centre, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Turner, S T" sort="Turner, S T" uniqKey="Turner S" first="S T" last="Turner">S T Turner</name>
<affiliation wicri:level="1"><nlm:aff id="aff104"><institution>Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic</institution>
, Rochester, MN,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Weir, D R" sort="Weir, D R" uniqKey="Weir D" first="D R" last="Weir">D R Weir</name>
<affiliation wicri:level="1"><nlm:aff id="aff58"><institution>Survey Research Center, Institute for Social Research, University of Michigan</institution>
, Ann Arbor, MI,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wilson, J F" sort="Wilson, J F" uniqKey="Wilson J" first="J F" last="Wilson">J F Wilson</name>
<affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Centre for Population Health Sciences, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Van Duijn, C" sort="Van Duijn, C" uniqKey="Van Duijn C" first="C" last="Van Duijn">C. Van Duijn</name>
<affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center</institution>
, Rotterdam,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Netherlands Consortium for Healthy Ageing</institution>
, Leiden,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Launer, L" sort="Launer, L" uniqKey="Launer L" first="L" last="Launer">L. Launer</name>
<affiliation wicri:level="1"><nlm:aff id="aff63"><institution>Intramural Research Program National Institutes on Aging, National Institutes of Health</institution>
, Bethesda, MD,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fitzpatrick, A L" sort="Fitzpatrick, A L" uniqKey="Fitzpatrick A" first="A L" last="Fitzpatrick">A L Fitzpatrick</name>
<affiliation wicri:level="1"><nlm:aff id="aff81"><institution>Deparment of Epidemiology, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff105"><institution>Department of Global Health, University of Washington</institution>
, Seattle, WA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Seshadri, S" sort="Seshadri, S" uniqKey="Seshadri S" first="S" last="Seshadri">S. Seshadri</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Neurology, Boston University School of Medicine</institution>
, Boston, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Framingham Heart Study</institution>
, Framingham, MA,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Mosley, T H" sort="Mosley, T H" uniqKey="Mosley T" first="T H" last="Mosley">T H Mosley</name>
<affiliation wicri:level="1"><nlm:aff id="aff93"><institution>Division of Geriatrics, Department of Medicine, University of Mississippi Medical Center</institution>
, Jackson, MS,<country>USA</country>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Deary, I J" sort="Deary, I J" uniqKey="Deary I" first="I J" last="Deary">I J Deary</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Psychology, University of Edinburgh</institution>
, Edinburgh,<country>UK</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Molecular Psychiatry</title>
<idno type="ISSN">1359-4184</idno>
<idno type="eISSN">1476-5578</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
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<front><div type="abstract" xml:lang="en"><p>General cognitive function is substantially heritable across the human life course from adolescence to old age. We investigated the genetic contribution to variation in this important, health- and well-being-related trait in middle-aged and older adults. We conducted a meta-analysis of genome-wide association studies of 31 cohorts (<italic>N</italic>
=53 949) in which the participants had undertaken multiple, diverse cognitive tests. A general cognitive function phenotype was tested for, and created in each cohort by principal component analysis. We report 13 genome-wide significant single-nucleotide polymorphism (SNP) associations in three genomic regions, 6q16.1, 14q12 and 19q13.32 (best SNP and closest gene, respectively: rs10457441, <italic>P</italic>
=3.93 × 10<sup>−9</sup>
, <italic>MIR2113</italic>
; rs17522122, <italic>P</italic>
=2.55 × 10<sup>−8</sup>
, <italic>AKAP6</italic>
; rs10119, <italic>P</italic>
=5.67 × 10<sup>−9</sup>
, <italic>APOE/TOMM40</italic>
). We report one gene-based significant association with the <italic>HMGN1</italic>
gene located on chromosome 21 (<italic>P</italic>
=1 × 10<sup>−6</sup>
). These genes have previously been associated with neuropsychiatric phenotypes. Meta-analysis results are consistent with a polygenic model of inheritance. To estimate SNP-based heritability, the genome-wide complex trait analysis procedure was applied to two large cohorts, the Atherosclerosis Risk in Communities Study (<italic>N</italic>
=6617) and the Health and Retirement Study (<italic>N</italic>
=5976). The proportion of phenotypic variation accounted for by all genotyped common SNPs was 29% (s.e.=5%) and 28% (s.e.=7%), respectively. Using polygenic prediction analysis, ~1.2% of the variance in general cognitive function was predicted in the Generation Scotland cohort (<italic>N</italic>
=5487; <italic>P</italic>
=1.5 × 10<sup>−17</sup>
). In hypothesis-driven tests, there was significant association between general cognitive function and four genes previously associated with Alzheimer's disease: <italic>TOMM40</italic>
, <italic>APOE</italic>
, <italic>ABCG1</italic>
and <italic>MEF2C</italic>
.</p>
</div>
</front>
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<pubmed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).</title>
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<affiliation wicri:level="2"><nlm:affiliation>1] Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique, Lille, France [2] Department of Neurology, Boston University School of Medicine, Boston, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique, Lille, France [2] Department of Neurology, Boston University School of Medicine, Boston, MA</wicri:regionArea>
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<country xml:lang="fr">Norvège</country>
<wicri:regionArea>1] K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen, Bergen, Norway [2] Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen</wicri:regionArea>
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</affiliation>
</author>
<author><name sortKey="Hofer, E" sort="Hofer, E" uniqKey="Hofer E" first="E" last="Hofer">E. Hofer</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Department of Neurology, Medical University of Graz, Graz, Austria [2] Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>1] Department of Neurology, Medical University of Graz, Graz, Austria [2] Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz</wicri:regionArea>
<wicri:noRegion>Graz</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ibrahim Verbaas, C A" sort="Ibrahim Verbaas, C A" uniqKey="Ibrahim Verbaas C" first="C A" last="Ibrahim-Verbaas">C A Ibrahim-Verbaas</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kirin, M" sort="Kirin, M" uniqKey="Kirin M" first="M" last="Kirin">M. Kirin</name>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Lahti, J" sort="Lahti, J" uniqKey="Lahti J" first="J" last="Lahti">J. Lahti</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland [2] Folkhälsan Research Centre, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>1] Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland [2] Folkhälsan Research Centre, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName><settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Van Der Lee, S J" sort="Van Der Lee, S J" uniqKey="Van Der Lee S" first="S J" last="Van Der Lee">S J Van Der Lee</name>
<affiliation wicri:level="3"><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Le Hellard, S" sort="Le Hellard, S" uniqKey="Le Hellard S" first="S" last="Le Hellard">S. Le Hellard</name>
<affiliation wicri:level="1"><nlm:affiliation>1] K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen, Bergen, Norway [2] Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>1] K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen, Bergen, Norway [2] Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen</wicri:regionArea>
<wicri:noRegion>Bergen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Liu, T" sort="Liu, T" uniqKey="Liu T" first="T" last="Liu">T. Liu</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Max Planck Institute for Human Development, Berlin, Germany [2] Max Planck Institute for Molecular Genetics, Berlin, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>1] Max Planck Institute for Human Development, Berlin, Germany [2] Max Planck Institute for Molecular Genetics, Berlin</wicri:regionArea>
<placeName><region type="land" nuts="3">Berlin</region>
<settlement type="city">Berlin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Marioni, R E" sort="Marioni, R E" uniqKey="Marioni R" first="R E" last="Marioni">R E Marioni</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK [3] Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK [3] Queensland Brain Institute, The University of Queensland, Brisbane, QLD</wicri:regionArea>
<orgName type="university">Université d'Édimbourg</orgName>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Oldmeadow, C" sort="Oldmeadow, C" uniqKey="Oldmeadow C" first="C" last="Oldmeadow">C. Oldmeadow</name>
<affiliation wicri:level="1"><nlm:affiliation>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Postmus, I" sort="Postmus, I" uniqKey="Postmus I" first="I" last="Postmus">I. Postmus</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Smith, A V" sort="Smith, A V" uniqKey="Smith A" first="A V" last="Smith">A V Smith</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Icelandic Heart Association, Kopavogur, Iceland [2] University of Iceland, Reykjavik, Iceland.</nlm:affiliation>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>1] Icelandic Heart Association, Kopavogur, Iceland [2] University of Iceland, Reykjavik</wicri:regionArea>
<wicri:noRegion>Reykjavik</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Smith, J A" sort="Smith, J A" uniqKey="Smith J" first="J A" last="Smith">J A Smith</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Thalamuthu, A" sort="Thalamuthu, A" uniqKey="Thalamuthu A" first="A" last="Thalamuthu">A. Thalamuthu</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Thomson, R" sort="Thomson, R" uniqKey="Thomson R" first="R" last="Thomson">R. Thomson</name>
<affiliation><nlm:affiliation>Menzies Research Institute, Hobart, Tasmania.</nlm:affiliation>
<wicri:noCountry code="subField">Tasmania</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Vitart, V" sort="Vitart, V" uniqKey="Vitart V" first="V" last="Vitart">V. Vitart</name>
<affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Wang, J" sort="Wang, J" uniqKey="Wang J" first="J" last="Wang">J. Wang</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Framingham Heart Study, Framingham, MA, USA [2] Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Framingham Heart Study, Framingham, MA, USA [2] Department of Biostatistics, Boston University School of Public Health, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yu, L" sort="Yu, L" uniqKey="Yu L" first="L" last="Yu">L. Yu</name>
<affiliation wicri:level="2"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zgaga, L" sort="Zgaga, L" uniqKey="Zgaga L" first="L" last="Zgaga">L. Zgaga</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Department of Public Health and Primary Care, Trinity College Dublin, Dublin, Ireland [2] Andrija Stampar School of Public Health, Medical School, University of Zagreb, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1] Department of Public Health and Primary Care, Trinity College Dublin, Dublin, Ireland [2] Andrija Stampar School of Public Health, Medical School, University of Zagreb, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhao, W" sort="Zhao, W" uniqKey="Zhao W" first="W" last="Zhao">W. Zhao</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Boxall, R" sort="Boxall, R" uniqKey="Boxall R" first="R" last="Boxall">R. Boxall</name>
<affiliation wicri:level="3"><nlm:affiliation>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Harris, S E" sort="Harris, S E" uniqKey="Harris S" first="S E" last="Harris">S E Harris</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Hill, W D" sort="Hill, W D" uniqKey="Hill W" first="W D" last="Hill">W D Hill</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Liewald, D C" sort="Liewald, D C" uniqKey="Liewald D" first="D C" last="Liewald">D C Liewald</name>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Luciano, M" sort="Luciano, M" uniqKey="Luciano M" first="M" last="Luciano">M. Luciano</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Adams, H" sort="Adams, H" uniqKey="Adams H" first="H" last="Adams">H. Adams</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ames, D" sort="Ames, D" uniqKey="Ames D" first="D" last="Ames">D. Ames</name>
<affiliation wicri:level="4"><nlm:affiliation>1] National Ageing Research Institute, Royal Melbourne Hospital, Melbourne, VIC, Australia [2] Academic Unit for Psychiatry of Old Age, St George's Hospital, University of Melbourne, Kew, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] National Ageing Research Institute, Royal Melbourne Hospital, Melbourne, VIC, Australia [2] Academic Unit for Psychiatry of Old Age, St George's Hospital, University of Melbourne, Kew</wicri:regionArea>
<orgName type="university">Université de Melbourne</orgName>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Amin, N" sort="Amin, N" uniqKey="Amin N" first="N" last="Amin">N. Amin</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Amouyel, P" sort="Amouyel, P" uniqKey="Amouyel P" first="P" last="Amouyel">P. Amouyel</name>
<affiliation wicri:level="3"><nlm:affiliation>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique, Lille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique, Lille</wicri:regionArea>
<placeName><region type="region">Hauts-de-France</region>
<region type="old region">Nord-Pas-de-Calais</region>
<settlement type="city">Lille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Assareh, A A" sort="Assareh, A A" uniqKey="Assareh A" first="A A" last="Assareh">A A Assareh</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Au, R" sort="Au, R" uniqKey="Au R" first="R" last="Au">R. Au</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Becker, J T" sort="Becker, J T" uniqKey="Becker J" first="J T" last="Becker">J T Becker</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA [2] Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA [3] Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA [2] Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA [3] Department of Psychology, University of Pittsburgh, Pittsburgh, PA</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">Pittsburgh</settlement>
</placeName>
<orgName type="university">Université de Pittsburgh</orgName>
</affiliation>
</author>
<author><name sortKey="Beiser, A" sort="Beiser, A" uniqKey="Beiser A" first="A" last="Beiser">A. Beiser</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Berr, C" sort="Berr, C" uniqKey="Berr C" first="C" last="Berr">C. Berr</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Inserm, U106, Montpellier, France [2] Université Montpellier I, Montpellier, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>1] Inserm, U106, Montpellier, France [2] Université Montpellier I, Montpellier</wicri:regionArea>
<placeName><region type="region">Occitanie (région administrative)</region>
<region type="old region">Languedoc-Roussillon</region>
<settlement type="city">Montpellier</settlement>
<settlement type="city">Montpellier</settlement>
</placeName>
<orgName type="university">Université Montpellier 1</orgName>
</affiliation>
</author>
<author><name sortKey="Bertram, L" sort="Bertram, L" uniqKey="Bertram L" first="L" last="Bertram">L. Bertram</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Max Planck Institute for Molecular Genetics, Berlin, Germany [2] Faculty of Medicine, School of Public Health, Imperial College, London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>1] Max Planck Institute for Molecular Genetics, Berlin, Germany [2] Faculty of Medicine, School of Public Health, Imperial College, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Boerwinkle, E" sort="Boerwinkle, E" uniqKey="Boerwinkle E" first="E" last="Boerwinkle">E. Boerwinkle</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA [2] Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas Health Science Center at Houston, Houston, TX, USA [3] Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA [2] Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas Health Science Center at Houston, Houston, TX, USA [3] Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX</wicri:regionArea>
<placeName><region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Buckley, B M" sort="Buckley, B M" uniqKey="Buckley B" first="B M" last="Buckley">B M Buckley</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology and Therapeutics, University College Cork, Cork, Ireland.</nlm:affiliation>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Department of Pharmacology and Therapeutics, University College Cork, Cork</wicri:regionArea>
<wicri:noRegion>Cork</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Campbell, H" sort="Campbell, H" uniqKey="Campbell H" first="H" last="Campbell">H. Campbell</name>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Corley, J" sort="Corley, J" uniqKey="Corley J" first="J" last="Corley">J. Corley</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="De Jager, P L" sort="De Jager, P L" uniqKey="De Jager P" first="P L" last="De Jager">P L De Jager</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA [2] Harvard Medical School, Boston, MA, USA [3] Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA [2] Harvard Medical School, Boston, MA, USA [3] Program in Medical and Population Genetics, Broad Institute, Cambridge, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dufouil, C" sort="Dufouil, C" uniqKey="Dufouil C" first="C" last="Dufouil">C. Dufouil</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Inserm U708, Neuroepidemiology, Paris, France [2] Inserm U897, Université Bordeaux Segalen, Bordeaux, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>1] Inserm U708, Neuroepidemiology, Paris, France [2] Inserm U897, Université Bordeaux Segalen, Bordeaux</wicri:regionArea>
<placeName><region type="region">Nouvelle-Aquitaine</region>
<region type="old region">Aquitaine</region>
<settlement type="city">Bordeaux</settlement>
<settlement type="city">Bordeaux</settlement>
</placeName>
<orgName type="university">Université Bordeaux II</orgName>
</affiliation>
</author>
<author><name sortKey="Eriksson, J G" sort="Eriksson, J G" uniqKey="Eriksson J" first="J G" last="Eriksson">J G Eriksson</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Folkhälsan Research Centre, Helsinki, Finland [2] National Institute for Health and Welfare, Helsinki, Finland [3] Department of General Practice and Primary health Care, University of Helsinki, Helsinki, Finland [4] Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>1] Folkhälsan Research Centre, Helsinki, Finland [2] National Institute for Health and Welfare, Helsinki, Finland [3] Department of General Practice and Primary health Care, University of Helsinki, Helsinki, Finland [4] Unit of General Practice, Helsinki University Central Hospital, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName><settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Espeseth, T" sort="Espeseth, T" uniqKey="Espeseth T" first="T" last="Espeseth">T. Espeseth</name>
<affiliation wicri:level="3"><nlm:affiliation>1] K.G. Jebsen Centre for Psychosis Research, Norwegian Centre For Mental Disorders Research (NORMENT), Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway [2] Department of Psychology, University of Oslo, Oslo, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>1] K.G. Jebsen Centre for Psychosis Research, Norwegian Centre For Mental Disorders Research (NORMENT), Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway [2] Department of Psychology, University of Oslo, Oslo</wicri:regionArea>
<placeName><settlement type="city">Oslo</settlement>
<region nuts="2">Østlandet</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Faul, J D" sort="Faul, J D" uniqKey="Faul J" first="J D" last="Faul">J D Faul</name>
<affiliation wicri:level="2"><nlm:affiliation>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ford, I" sort="Ford, I" uniqKey="Ford I" first="I" last="Ford">I. Ford</name>
<affiliation wicri:level="1"><nlm:affiliation>Robertson Center for Biostatistics, Glasgow, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Robertson Center for Biostatistics, Glasgow</wicri:regionArea>
<wicri:noRegion>Glasgow</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gottesman, R F" sort="Gottesman, R F" uniqKey="Gottesman R" first="R F" last="Gottesman">R F Gottesman</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Griswold, M E" sort="Griswold, M E" uniqKey="Griswold M" first="M E" last="Griswold">M E Griswold</name>
<affiliation wicri:level="2"><nlm:affiliation>Center of Biostatistics and Bioinformatics, University of Mississippi Medical Center, Jackson, MS, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center of Biostatistics and Bioinformatics, University of Mississippi Medical Center, Jackson, MS</wicri:regionArea>
<placeName><region type="state">État du Mississippi</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gudnason, V" sort="Gudnason, V" uniqKey="Gudnason V" first="V" last="Gudnason">V. Gudnason</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Icelandic Heart Association, Kopavogur, Iceland [2] University of Iceland, Reykjavik, Iceland.</nlm:affiliation>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>1] Icelandic Heart Association, Kopavogur, Iceland [2] University of Iceland, Reykjavik</wicri:regionArea>
<wicri:noRegion>Reykjavik</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Harris, T B" sort="Harris, T B" uniqKey="Harris T" first="T B" last="Harris">T B Harris</name>
<affiliation wicri:level="2"><nlm:affiliation>Intramural Research Program National Institutes on Aging, National Institutes of Health, Bethesda, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Intramural Research Program National Institutes on Aging, National Institutes of Health, Bethesda, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Heiss, G" sort="Heiss, G" uniqKey="Heiss G" first="G" last="Heiss">G. Heiss</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hofman, A" sort="Hofman, A" uniqKey="Hofman A" first="A" last="Hofman">A. Hofman</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Holliday, E G" sort="Holliday, E G" uniqKey="Holliday E" first="E G" last="Holliday">E G Holliday</name>
<affiliation wicri:level="1"><nlm:affiliation>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Huffman, J" sort="Huffman, J" uniqKey="Huffman J" first="J" last="Huffman">J. Huffman</name>
<affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Kardia, S L R" sort="Kardia, S L R" uniqKey="Kardia S" first="S L R" last="Kardia">S L R. Kardia</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kochan, N" sort="Kochan, N" uniqKey="Kochan N" first="N" last="Kochan">N. Kochan</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Knopman, D S" sort="Knopman, D S" uniqKey="Knopman D" first="D S" last="Knopman">D S Knopman</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, Mayo Clinic, Rochester, MN, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Mayo Clinic, Rochester, MN</wicri:regionArea>
<placeName><region type="state">Minnesota</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kwok, J B" sort="Kwok, J B" uniqKey="Kwok J" first="J B" last="Kwok">J B Kwok</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Neuroscience Research Australia, Randwick, NSW, Australia [2] School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Neuroscience Research Australia, Randwick, NSW, Australia [2] School of Medical Sciences, University of New South Wales, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lambert, J C" sort="Lambert, J C" uniqKey="Lambert J" first="J-C" last="Lambert">J-C Lambert</name>
<affiliation wicri:level="3"><nlm:affiliation>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique, Lille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique, Lille</wicri:regionArea>
<placeName><region type="region">Hauts-de-France</region>
<region type="old region">Nord-Pas-de-Calais</region>
<settlement type="city">Lille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lee, T" sort="Lee, T" uniqKey="Lee T" first="T" last="Lee">T. Lee</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Li, G" sort="Li, G" uniqKey="Li G" first="G" last="Li">G. Li</name>
<affiliation wicri:level="4"><nlm:affiliation>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Li, S C" sort="Li, S C" uniqKey="Li S" first="S-C" last="Li">S-C Li</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Max Planck Institute for Human Development, Berlin, Germany [2] Technische Universität Dresden, Dresden, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>1] Max Planck Institute for Human Development, Berlin, Germany [2] Technische Universität Dresden, Dresden</wicri:regionArea>
<placeName><region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
<settlement type="city">Dresde</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Loitfelder, M" sort="Loitfelder, M" uniqKey="Loitfelder M" first="M" last="Loitfelder">M. Loitfelder</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Medical University of Graz, Graz, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Neurology, Medical University of Graz, Graz</wicri:regionArea>
<wicri:noRegion>Graz</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lopez, O L" sort="Lopez, O L" uniqKey="Lopez O" first="O L" last="Lopez">O L Lopez</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of Pittsburgh, Pittsburgh, PA</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">Pittsburgh</settlement>
</placeName>
<orgName type="university">Université de Pittsburgh</orgName>
</affiliation>
</author>
<author><name sortKey="Lundervold, A J" sort="Lundervold, A J" uniqKey="Lundervold A" first="A J" last="Lundervold">A J Lundervold</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway [2] Kavli Research Centre for Aging and Dementia, Haraldsplass Deaconess Hospital, Bergen, Norway [3] K.G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>1] Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway [2] Kavli Research Centre for Aging and Dementia, Haraldsplass Deaconess Hospital, Bergen, Norway [3] K.G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen, Bergen</wicri:regionArea>
<wicri:noRegion>Bergen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lundqvist, A" sort="Lundqvist, A" uniqKey="Lundqvist A" first="A" last="Lundqvist">A. Lundqvist</name>
<affiliation wicri:level="1"><nlm:affiliation>Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå</wicri:regionArea>
<wicri:noRegion>Umeå</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mather, K A" sort="Mather, K A" uniqKey="Mather K" first="K A" last="Mather">K A Mather</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mirza, S S" sort="Mirza, S S" uniqKey="Mirza S" first="S S" last="Mirza">S S Mirza</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nyberg, L" sort="Nyberg, L" uniqKey="Nyberg L" first="L" last="Nyberg">L. Nyberg</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden [2] Department of Radiation Sciences, Umeå University, Umeå, Sweden [3] Department of Integrative Medical Biology, Umeå University, Umeå, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>1] Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden [2] Department of Radiation Sciences, Umeå University, Umeå, Sweden [3] Department of Integrative Medical Biology, Umeå University, Umeå</wicri:regionArea>
<wicri:noRegion>Umeå</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Oostra, B A" sort="Oostra, B A" uniqKey="Oostra B" first="B A" last="Oostra">B A Oostra</name>
<affiliation wicri:level="3"><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Palotie, A" sort="Palotie, A" uniqKey="Palotie A" first="A" last="Palotie">A. Palotie</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK [2] Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland [3] Department of Medical Genetics, University of Helsinki and University Central Hospital, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>1] Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK [2] Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland [3] Department of Medical Genetics, University of Helsinki and University Central Hospital, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName><settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Papenberg, G" sort="Papenberg, G" uniqKey="Papenberg G" first="G" last="Papenberg">G. Papenberg</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Max Planck Institute for Human Development, Berlin, Germany [2] Karolinska Institutet, Aging Research Center, Stockholm University, Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>1] Max Planck Institute for Human Development, Berlin, Germany [2] Karolinska Institutet, Aging Research Center, Stockholm University, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
<settlement type="city">Stockholm</settlement>
</placeName>
<orgName type="university">Université de Stockholm</orgName>
</affiliation>
</author>
<author><name sortKey="Pattie, A" sort="Pattie, A" uniqKey="Pattie A" first="A" last="Pattie">A. Pattie</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Petrovic, K" sort="Petrovic, K" uniqKey="Petrovic K" first="K" last="Petrovic">K. Petrovic</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Medical University of Graz, Graz, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Neurology, Medical University of Graz, Graz</wicri:regionArea>
<wicri:noRegion>Graz</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Polasek, O" sort="Polasek, O" uniqKey="Polasek O" first="O" last="Polasek">O. Polasek</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Medicine, Department of Public Health, University of Split, Split, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Faculty of Medicine, Department of Public Health, University of Split, Split</wicri:regionArea>
<wicri:noRegion>Split</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Psaty, B M" sort="Psaty, B M" uniqKey="Psaty B" first="B M" last="Psaty">B M Psaty</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA [2] Deparment of Epidemiology, University of Washington, Seattle, WA, USA [3] Deparment of Health Services, University of Washington, Seattle, WA, USA [4] Group Health Research Unit, Group Health Cooperative, Seattle, WA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA [2] Deparment of Epidemiology, University of Washington, Seattle, WA, USA [3] Deparment of Health Services, University of Washington, Seattle, WA, USA [4] Group Health Research Unit, Group Health Cooperative, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Redmond, P" sort="Redmond, P" uniqKey="Redmond P" first="P" last="Redmond">P. Redmond</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Reppermund, S" sort="Reppermund, S" uniqKey="Reppermund S" first="S" last="Reppermund">S. Reppermund</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rotter, J I" sort="Rotter, J I" uniqKey="Rotter J" first="J I" last="Rotter">J I Rotter</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center, Los Angeles, CA, USA [2] Division of Genetic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center, Los Angeles, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center, Los Angeles, CA, USA [2] Division of Genetic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center, Los Angeles, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schmidt, H" sort="Schmidt, H" uniqKey="Schmidt H" first="H" last="Schmidt">H. Schmidt</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Department of Neurology, Medical University of Graz, Graz, Austria [2] Centre for Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>1] Department of Neurology, Medical University of Graz, Graz, Austria [2] Centre for Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz</wicri:regionArea>
<wicri:noRegion>Graz</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schuur, M" sort="Schuur, M" uniqKey="Schuur M" first="M" last="Schuur">M. Schuur</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schofield, P W" sort="Schofield, P W" uniqKey="Schofield P" first="P W" last="Schofield">P W Schofield</name>
<affiliation wicri:level="1"><nlm:affiliation>School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Medicine and Public Health, University of Newcastle, Newcastle, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Scott, R J" sort="Scott, R J" uniqKey="Scott R" first="R J" last="Scott">R J Scott</name>
<affiliation wicri:level="1"><nlm:affiliation>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Steen, V M" sort="Steen, V M" uniqKey="Steen V" first="V M" last="Steen">V M Steen</name>
<affiliation wicri:level="1"><nlm:affiliation>1] K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen, Bergen, Norway [2] Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>1] K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen, Bergen, Norway [2] Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen</wicri:regionArea>
<wicri:noRegion>Bergen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stott, D J" sort="Stott, D J" uniqKey="Stott D" first="D J" last="Stott">D J Stott</name>
<affiliation wicri:level="4"><nlm:affiliation>Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow</wicri:regionArea>
<orgName type="university">Université de Glasgow</orgName>
<placeName><settlement type="city">Glasgow</settlement>
<region type="country">Écosse</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Van Swieten, J C" sort="Van Swieten, J C" uniqKey="Van Swieten J" first="J C" last="Van Swieten">J C Van Swieten</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Erasmus University Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Taylor, K D" sort="Taylor, K D" uniqKey="Taylor K" first="K D" last="Taylor">K D Taylor</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center, Los Angeles, CA, USA [2] Department of Pediatrics, Harbor-UCLA Medical Center, Los Angeles, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center, Los Angeles, CA, USA [2] Department of Pediatrics, Harbor-UCLA Medical Center, Los Angeles, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Trollor, J" sort="Trollor, J" uniqKey="Trollor J" first="J" last="Trollor">J. Trollor</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Trompet, S" sort="Trompet, S" uniqKey="Trompet S" first="S" last="Trompet">S. Trompet</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands [2] Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands [2] Department of Cardiology, Leiden University Medical Center, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Uitterlinden, A G" sort="Uitterlinden, A G" uniqKey="Uitterlinden A" first="A G" last="Uitterlinden">A G Uitterlinden</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands [3] Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands [3] Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Weinstein, G" sort="Weinstein, G" uniqKey="Weinstein G" first="G" last="Weinstein">G. Weinstein</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Widen, E" sort="Widen, E" uniqKey="Widen E" first="E" last="Widen">E. Widen</name>
<affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName><settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Windham, B G" sort="Windham, B G" uniqKey="Windham B" first="B G" last="Windham">B G Windham</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Geriatrics, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Geriatrics, Department of Medicine, University of Mississippi Medical Center, Jackson, MS</wicri:regionArea>
<placeName><region type="state">État du Mississippi</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jukema, J W" sort="Jukema, J W" uniqKey="Jukema J" first="J W" last="Jukema">J W Jukema</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands [2] Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands [3] Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands [2] Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands [3] Interuniversity Cardiology Institute of the Netherlands, Utrecht</wicri:regionArea>
<placeName><settlement type="city">Utrecht</settlement>
<region nuts="2" type="province">Utrecht (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wright, A F" sort="Wright, A F" uniqKey="Wright A" first="A F" last="Wright">A F Wright</name>
<affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Wright, M J" sort="Wright, M J" uniqKey="Wright M" first="M J" last="Wright">M J Wright</name>
<affiliation wicri:level="1"><nlm:affiliation>Neuroimaging Genetics Group, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Neuroimaging Genetics Group, QIMR Berghofer Medical Research Institute, Brisbane, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Yang, Q" sort="Yang, Q" uniqKey="Yang Q" first="Q" last="Yang">Q. Yang</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Framingham Heart Study, Framingham, MA, USA [2] Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Framingham Heart Study, Framingham, MA, USA [2] Department of Biostatistics, Boston University School of Public Health, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Amieva, H" sort="Amieva, H" uniqKey="Amieva H" first="H" last="Amieva">H. Amieva</name>
<affiliation wicri:level="4"><nlm:affiliation>Inserm U897, Université Bordeaux Segalen, Bordeaux, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Inserm U897, Université Bordeaux Segalen, Bordeaux</wicri:regionArea>
<placeName><region type="region">Nouvelle-Aquitaine</region>
<region type="old region">Aquitaine</region>
<settlement type="city">Bordeaux</settlement>
<settlement type="city">Bordeaux</settlement>
</placeName>
<orgName type="university">Université Bordeaux II</orgName>
</affiliation>
</author>
<author><name sortKey="Attia, J R" sort="Attia, J R" uniqKey="Attia J" first="J R" last="Attia">J R Attia</name>
<affiliation wicri:level="1"><nlm:affiliation>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bennett, D A" sort="Bennett, D A" uniqKey="Bennett D" first="D A" last="Bennett">D A Bennett</name>
<affiliation wicri:level="2"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Brodaty, H" sort="Brodaty, H" uniqKey="Brodaty H" first="H" last="Brodaty">H. Brodaty</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Dementia Collaborative Research Centre, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Dementia Collaborative Research Centre, University of New South Wales, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="De Craen, A J M" sort="De Craen, A J M" uniqKey="De Craen A" first="A J M" last="De Craen">A J M. De Craen</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hayward, C" sort="Hayward, C" uniqKey="Hayward C" first="C" last="Hayward">C. Hayward</name>
<affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Ikram, M A" sort="Ikram, M A" uniqKey="Ikram M" first="M A" last="Ikram">M A Ikram</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [3] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands [4] Department of Radiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [3] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands [4] Department of Radiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lindenberger, U" sort="Lindenberger, U" uniqKey="Lindenberger U" first="U" last="Lindenberger">U. Lindenberger</name>
<affiliation wicri:level="3"><nlm:affiliation>Max Planck Institute for Human Development, Berlin, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Max Planck Institute for Human Development, Berlin</wicri:regionArea>
<placeName><region type="land" nuts="3">Berlin</region>
<settlement type="city">Berlin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nilsson, L G" sort="Nilsson, L G" uniqKey="Nilsson L" first="L-G" last="Nilsson">L-G Nilsson</name>
<affiliation wicri:level="1"><nlm:affiliation>ARC, Karolinska Institutet, Stockholm and UFBI, Umeå University, Umeå, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>ARC, Karolinska Institutet, Stockholm and UFBI, Umeå University, Umeå</wicri:regionArea>
<wicri:noRegion>Umeå</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Porteous, D J" sort="Porteous, D J" uniqKey="Porteous D" first="D J" last="Porteous">D J Porteous</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK [3] Generation Scotland, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK [3] Generation Scotland, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="R Ikkonen, K" sort="R Ikkonen, K" uniqKey="R Ikkonen K" first="K" last="R Ikkönen">K. R Ikkönen</name>
<affiliation wicri:level="4"><nlm:affiliation>Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName><settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Reinvang, I" sort="Reinvang, I" uniqKey="Reinvang I" first="I" last="Reinvang">I. Reinvang</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Psychology, University of Oslo, Oslo, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Department of Psychology, University of Oslo, Oslo</wicri:regionArea>
<placeName><settlement type="city">Oslo</settlement>
<region nuts="2">Østlandet</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rudan, I" sort="Rudan, I" uniqKey="Rudan I" first="I" last="Rudan">I. Rudan</name>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Sachdev, P S" sort="Sachdev, P S" uniqKey="Sachdev P" first="P S" last="Sachdev">P S Sachdev</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schmidt, R" sort="Schmidt, R" uniqKey="Schmidt R" first="R" last="Schmidt">R. Schmidt</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Medical University of Graz, Graz, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Neurology, Medical University of Graz, Graz</wicri:regionArea>
<wicri:noRegion>Graz</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schofield, P R" sort="Schofield, P R" uniqKey="Schofield P" first="P R" last="Schofield">P R Schofield</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Neuroscience Research Australia, Sydney, NSW, Australia [2] Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Neuroscience Research Australia, Sydney, NSW, Australia [2] Faculty of Medicine, University of New South Wales, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Srikanth, V" sort="Srikanth, V" uniqKey="Srikanth V" first="V" last="Srikanth">V. Srikanth</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Menzies Research Institute, Hobart, Tasmania [2] Stroke and Ageing Research, Medicine, Southern Clinical School, Monash University, Melbourne, VIC, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Menzies Research Institute, Hobart, Tasmania [2] Stroke and Ageing Research, Medicine, Southern Clinical School, Monash University, Melbourne, VIC</wicri:regionArea>
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</affiliation>
</author>
<author><name sortKey="Starr, J M" sort="Starr, J M" uniqKey="Starr J" first="J M" last="Starr">J M Starr</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
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<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Turner, S T" sort="Turner, S T" uniqKey="Turner S" first="S T" last="Turner">S T Turner</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.</nlm:affiliation>
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<author><name sortKey="Weir, D R" sort="Weir, D R" uniqKey="Weir D" first="D R" last="Weir">D R Weir</name>
<affiliation wicri:level="2"><nlm:affiliation>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wilson, J F" sort="Wilson, J F" uniqKey="Wilson J" first="J F" last="Wilson">J F Wilson</name>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
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<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Van Duijn, C" sort="Van Duijn, C" uniqKey="Van Duijn C" first="C" last="Van Duijn">C. Van Duijn</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
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</affiliation>
</author>
<author><name sortKey="Launer, L" sort="Launer, L" uniqKey="Launer L" first="L" last="Launer">L. Launer</name>
<affiliation wicri:level="2"><nlm:affiliation>Intramural Research Program National Institutes on Aging, National Institutes of Health, Bethesda, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Intramural Research Program National Institutes on Aging, National Institutes of Health, Bethesda, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fitzpatrick, A L" sort="Fitzpatrick, A L" uniqKey="Fitzpatrick A" first="A L" last="Fitzpatrick">A L Fitzpatrick</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Deparment of Epidemiology, University of Washington, Seattle, WA, USA [2] Department of Global Health, University of Washington, Seattle, WA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Deparment of Epidemiology, University of Washington, Seattle, WA, USA [2] Department of Global Health, University of Washington, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Seshadri, S" sort="Seshadri, S" uniqKey="Seshadri S" first="S" last="Seshadri">S. Seshadri</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mosley, T H" sort="Mosley, T H" uniqKey="Mosley T" first="T H" last="Mosley">T H Mosley</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Geriatrics, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Geriatrics, Department of Medicine, University of Mississippi Medical Center, Jackson, MS</wicri:regionArea>
<placeName><region type="state">État du Mississippi</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Deary, I J" sort="Deary, I J" uniqKey="Deary I" first="I J" last="Deary">I J Deary</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).</title>
<author><name sortKey="Davies, G" sort="Davies, G" uniqKey="Davies G" first="G" last="Davies">G. Davies</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Armstrong, N" sort="Armstrong, N" uniqKey="Armstrong N" first="N" last="Armstrong">N. Armstrong</name>
<affiliation wicri:level="4"><nlm:affiliation>School of Mathematics and Statistics, University of Sydney, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Mathematics and Statistics, University of Sydney, Sydney, NSW</wicri:regionArea>
<orgName type="university">Université de Sydney</orgName>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bis, J C" sort="Bis, J C" uniqKey="Bis J" first="J C" last="Bis">J C Bis</name>
<affiliation wicri:level="4"><nlm:affiliation>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Bressler, J" sort="Bressler, J" uniqKey="Bressler J" first="J" last="Bressler">J. Bressler</name>
<affiliation wicri:level="2"><nlm:affiliation>Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX</wicri:regionArea>
<placeName><region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chouraki, V" sort="Chouraki, V" uniqKey="Chouraki V" first="V" last="Chouraki">V. Chouraki</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique, Lille, France [2] Department of Neurology, Boston University School of Medicine, Boston, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique, Lille, France [2] Department of Neurology, Boston University School of Medicine, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Giddaluru, S" sort="Giddaluru, S" uniqKey="Giddaluru S" first="S" last="Giddaluru">S. Giddaluru</name>
<affiliation wicri:level="1"><nlm:affiliation>1] K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen, Bergen, Norway [2] Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>1] K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen, Bergen, Norway [2] Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen</wicri:regionArea>
<wicri:noRegion>Bergen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hofer, E" sort="Hofer, E" uniqKey="Hofer E" first="E" last="Hofer">E. Hofer</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Department of Neurology, Medical University of Graz, Graz, Austria [2] Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>1] Department of Neurology, Medical University of Graz, Graz, Austria [2] Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz</wicri:regionArea>
<wicri:noRegion>Graz</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ibrahim Verbaas, C A" sort="Ibrahim Verbaas, C A" uniqKey="Ibrahim Verbaas C" first="C A" last="Ibrahim-Verbaas">C A Ibrahim-Verbaas</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
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</affiliation>
</author>
<author><name sortKey="Kirin, M" sort="Kirin, M" uniqKey="Kirin M" first="M" last="Kirin">M. Kirin</name>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Lahti, J" sort="Lahti, J" uniqKey="Lahti J" first="J" last="Lahti">J. Lahti</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland [2] Folkhälsan Research Centre, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>1] Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland [2] Folkhälsan Research Centre, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName><settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Van Der Lee, S J" sort="Van Der Lee, S J" uniqKey="Van Der Lee S" first="S J" last="Van Der Lee">S J Van Der Lee</name>
<affiliation wicri:level="3"><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
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</placeName>
</affiliation>
</author>
<author><name sortKey="Le Hellard, S" sort="Le Hellard, S" uniqKey="Le Hellard S" first="S" last="Le Hellard">S. Le Hellard</name>
<affiliation wicri:level="1"><nlm:affiliation>1] K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen, Bergen, Norway [2] Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>1] K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen, Bergen, Norway [2] Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen</wicri:regionArea>
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</affiliation>
</author>
<author><name sortKey="Liu, T" sort="Liu, T" uniqKey="Liu T" first="T" last="Liu">T. Liu</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Max Planck Institute for Human Development, Berlin, Germany [2] Max Planck Institute for Molecular Genetics, Berlin, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>1] Max Planck Institute for Human Development, Berlin, Germany [2] Max Planck Institute for Molecular Genetics, Berlin</wicri:regionArea>
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<settlement type="city">Berlin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Marioni, R E" sort="Marioni, R E" uniqKey="Marioni R" first="R E" last="Marioni">R E Marioni</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK [3] Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK [3] Queensland Brain Institute, The University of Queensland, Brisbane, QLD</wicri:regionArea>
<orgName type="university">Université d'Édimbourg</orgName>
<placeName><settlement type="city">Édimbourg</settlement>
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</placeName>
</affiliation>
</author>
<author><name sortKey="Oldmeadow, C" sort="Oldmeadow, C" uniqKey="Oldmeadow C" first="C" last="Oldmeadow">C. Oldmeadow</name>
<affiliation wicri:level="1"><nlm:affiliation>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW</wicri:regionArea>
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</author>
<author><name sortKey="Postmus, I" sort="Postmus, I" uniqKey="Postmus I" first="I" last="Postmus">I. Postmus</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Smith, A V" sort="Smith, A V" uniqKey="Smith A" first="A V" last="Smith">A V Smith</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Icelandic Heart Association, Kopavogur, Iceland [2] University of Iceland, Reykjavik, Iceland.</nlm:affiliation>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>1] Icelandic Heart Association, Kopavogur, Iceland [2] University of Iceland, Reykjavik</wicri:regionArea>
<wicri:noRegion>Reykjavik</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Smith, J A" sort="Smith, J A" uniqKey="Smith J" first="J A" last="Smith">J A Smith</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Thalamuthu, A" sort="Thalamuthu, A" uniqKey="Thalamuthu A" first="A" last="Thalamuthu">A. Thalamuthu</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW</wicri:regionArea>
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</affiliation>
</author>
<author><name sortKey="Thomson, R" sort="Thomson, R" uniqKey="Thomson R" first="R" last="Thomson">R. Thomson</name>
<affiliation><nlm:affiliation>Menzies Research Institute, Hobart, Tasmania.</nlm:affiliation>
<wicri:noCountry code="subField">Tasmania</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Vitart, V" sort="Vitart, V" uniqKey="Vitart V" first="V" last="Vitart">V. Vitart</name>
<affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Wang, J" sort="Wang, J" uniqKey="Wang J" first="J" last="Wang">J. Wang</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Framingham Heart Study, Framingham, MA, USA [2] Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Framingham Heart Study, Framingham, MA, USA [2] Department of Biostatistics, Boston University School of Public Health, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yu, L" sort="Yu, L" uniqKey="Yu L" first="L" last="Yu">L. Yu</name>
<affiliation wicri:level="2"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zgaga, L" sort="Zgaga, L" uniqKey="Zgaga L" first="L" last="Zgaga">L. Zgaga</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Department of Public Health and Primary Care, Trinity College Dublin, Dublin, Ireland [2] Andrija Stampar School of Public Health, Medical School, University of Zagreb, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>1] Department of Public Health and Primary Care, Trinity College Dublin, Dublin, Ireland [2] Andrija Stampar School of Public Health, Medical School, University of Zagreb, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhao, W" sort="Zhao, W" uniqKey="Zhao W" first="W" last="Zhao">W. Zhao</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Boxall, R" sort="Boxall, R" uniqKey="Boxall R" first="R" last="Boxall">R. Boxall</name>
<affiliation wicri:level="3"><nlm:affiliation>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Harris, S E" sort="Harris, S E" uniqKey="Harris S" first="S E" last="Harris">S E Harris</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Hill, W D" sort="Hill, W D" uniqKey="Hill W" first="W D" last="Hill">W D Hill</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Liewald, D C" sort="Liewald, D C" uniqKey="Liewald D" first="D C" last="Liewald">D C Liewald</name>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Luciano, M" sort="Luciano, M" uniqKey="Luciano M" first="M" last="Luciano">M. Luciano</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Adams, H" sort="Adams, H" uniqKey="Adams H" first="H" last="Adams">H. Adams</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ames, D" sort="Ames, D" uniqKey="Ames D" first="D" last="Ames">D. Ames</name>
<affiliation wicri:level="4"><nlm:affiliation>1] National Ageing Research Institute, Royal Melbourne Hospital, Melbourne, VIC, Australia [2] Academic Unit for Psychiatry of Old Age, St George's Hospital, University of Melbourne, Kew, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] National Ageing Research Institute, Royal Melbourne Hospital, Melbourne, VIC, Australia [2] Academic Unit for Psychiatry of Old Age, St George's Hospital, University of Melbourne, Kew</wicri:regionArea>
<orgName type="university">Université de Melbourne</orgName>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Amin, N" sort="Amin, N" uniqKey="Amin N" first="N" last="Amin">N. Amin</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Amouyel, P" sort="Amouyel, P" uniqKey="Amouyel P" first="P" last="Amouyel">P. Amouyel</name>
<affiliation wicri:level="3"><nlm:affiliation>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique, Lille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique, Lille</wicri:regionArea>
<placeName><region type="region">Hauts-de-France</region>
<region type="old region">Nord-Pas-de-Calais</region>
<settlement type="city">Lille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Assareh, A A" sort="Assareh, A A" uniqKey="Assareh A" first="A A" last="Assareh">A A Assareh</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Au, R" sort="Au, R" uniqKey="Au R" first="R" last="Au">R. Au</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Becker, J T" sort="Becker, J T" uniqKey="Becker J" first="J T" last="Becker">J T Becker</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA [2] Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA [3] Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA [2] Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA [3] Department of Psychology, University of Pittsburgh, Pittsburgh, PA</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">Pittsburgh</settlement>
</placeName>
<orgName type="university">Université de Pittsburgh</orgName>
</affiliation>
</author>
<author><name sortKey="Beiser, A" sort="Beiser, A" uniqKey="Beiser A" first="A" last="Beiser">A. Beiser</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Berr, C" sort="Berr, C" uniqKey="Berr C" first="C" last="Berr">C. Berr</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Inserm, U106, Montpellier, France [2] Université Montpellier I, Montpellier, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>1] Inserm, U106, Montpellier, France [2] Université Montpellier I, Montpellier</wicri:regionArea>
<placeName><region type="region">Occitanie (région administrative)</region>
<region type="old region">Languedoc-Roussillon</region>
<settlement type="city">Montpellier</settlement>
<settlement type="city">Montpellier</settlement>
</placeName>
<orgName type="university">Université Montpellier 1</orgName>
</affiliation>
</author>
<author><name sortKey="Bertram, L" sort="Bertram, L" uniqKey="Bertram L" first="L" last="Bertram">L. Bertram</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Max Planck Institute for Molecular Genetics, Berlin, Germany [2] Faculty of Medicine, School of Public Health, Imperial College, London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>1] Max Planck Institute for Molecular Genetics, Berlin, Germany [2] Faculty of Medicine, School of Public Health, Imperial College, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Boerwinkle, E" sort="Boerwinkle, E" uniqKey="Boerwinkle E" first="E" last="Boerwinkle">E. Boerwinkle</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA [2] Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas Health Science Center at Houston, Houston, TX, USA [3] Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA [2] Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas Health Science Center at Houston, Houston, TX, USA [3] Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX</wicri:regionArea>
<placeName><region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Buckley, B M" sort="Buckley, B M" uniqKey="Buckley B" first="B M" last="Buckley">B M Buckley</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology and Therapeutics, University College Cork, Cork, Ireland.</nlm:affiliation>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Department of Pharmacology and Therapeutics, University College Cork, Cork</wicri:regionArea>
<wicri:noRegion>Cork</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Campbell, H" sort="Campbell, H" uniqKey="Campbell H" first="H" last="Campbell">H. Campbell</name>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Corley, J" sort="Corley, J" uniqKey="Corley J" first="J" last="Corley">J. Corley</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="De Jager, P L" sort="De Jager, P L" uniqKey="De Jager P" first="P L" last="De Jager">P L De Jager</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA [2] Harvard Medical School, Boston, MA, USA [3] Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA [2] Harvard Medical School, Boston, MA, USA [3] Program in Medical and Population Genetics, Broad Institute, Cambridge, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dufouil, C" sort="Dufouil, C" uniqKey="Dufouil C" first="C" last="Dufouil">C. Dufouil</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Inserm U708, Neuroepidemiology, Paris, France [2] Inserm U897, Université Bordeaux Segalen, Bordeaux, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>1] Inserm U708, Neuroepidemiology, Paris, France [2] Inserm U897, Université Bordeaux Segalen, Bordeaux</wicri:regionArea>
<placeName><region type="region">Nouvelle-Aquitaine</region>
<region type="old region">Aquitaine</region>
<settlement type="city">Bordeaux</settlement>
<settlement type="city">Bordeaux</settlement>
</placeName>
<orgName type="university">Université Bordeaux II</orgName>
</affiliation>
</author>
<author><name sortKey="Eriksson, J G" sort="Eriksson, J G" uniqKey="Eriksson J" first="J G" last="Eriksson">J G Eriksson</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Folkhälsan Research Centre, Helsinki, Finland [2] National Institute for Health and Welfare, Helsinki, Finland [3] Department of General Practice and Primary health Care, University of Helsinki, Helsinki, Finland [4] Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>1] Folkhälsan Research Centre, Helsinki, Finland [2] National Institute for Health and Welfare, Helsinki, Finland [3] Department of General Practice and Primary health Care, University of Helsinki, Helsinki, Finland [4] Unit of General Practice, Helsinki University Central Hospital, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName><settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Espeseth, T" sort="Espeseth, T" uniqKey="Espeseth T" first="T" last="Espeseth">T. Espeseth</name>
<affiliation wicri:level="3"><nlm:affiliation>1] K.G. Jebsen Centre for Psychosis Research, Norwegian Centre For Mental Disorders Research (NORMENT), Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway [2] Department of Psychology, University of Oslo, Oslo, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>1] K.G. Jebsen Centre for Psychosis Research, Norwegian Centre For Mental Disorders Research (NORMENT), Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway [2] Department of Psychology, University of Oslo, Oslo</wicri:regionArea>
<placeName><settlement type="city">Oslo</settlement>
<region nuts="2">Østlandet</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Faul, J D" sort="Faul, J D" uniqKey="Faul J" first="J D" last="Faul">J D Faul</name>
<affiliation wicri:level="2"><nlm:affiliation>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ford, I" sort="Ford, I" uniqKey="Ford I" first="I" last="Ford">I. Ford</name>
<affiliation wicri:level="1"><nlm:affiliation>Robertson Center for Biostatistics, Glasgow, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Robertson Center for Biostatistics, Glasgow</wicri:regionArea>
<wicri:noRegion>Glasgow</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gottesman, R F" sort="Gottesman, R F" uniqKey="Gottesman R" first="R F" last="Gottesman">R F Gottesman</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Griswold, M E" sort="Griswold, M E" uniqKey="Griswold M" first="M E" last="Griswold">M E Griswold</name>
<affiliation wicri:level="2"><nlm:affiliation>Center of Biostatistics and Bioinformatics, University of Mississippi Medical Center, Jackson, MS, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center of Biostatistics and Bioinformatics, University of Mississippi Medical Center, Jackson, MS</wicri:regionArea>
<placeName><region type="state">État du Mississippi</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gudnason, V" sort="Gudnason, V" uniqKey="Gudnason V" first="V" last="Gudnason">V. Gudnason</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Icelandic Heart Association, Kopavogur, Iceland [2] University of Iceland, Reykjavik, Iceland.</nlm:affiliation>
<country xml:lang="fr">Islande</country>
<wicri:regionArea>1] Icelandic Heart Association, Kopavogur, Iceland [2] University of Iceland, Reykjavik</wicri:regionArea>
<wicri:noRegion>Reykjavik</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Harris, T B" sort="Harris, T B" uniqKey="Harris T" first="T B" last="Harris">T B Harris</name>
<affiliation wicri:level="2"><nlm:affiliation>Intramural Research Program National Institutes on Aging, National Institutes of Health, Bethesda, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Intramural Research Program National Institutes on Aging, National Institutes of Health, Bethesda, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Heiss, G" sort="Heiss, G" uniqKey="Heiss G" first="G" last="Heiss">G. Heiss</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hofman, A" sort="Hofman, A" uniqKey="Hofman A" first="A" last="Hofman">A. Hofman</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Holliday, E G" sort="Holliday, E G" uniqKey="Holliday E" first="E G" last="Holliday">E G Holliday</name>
<affiliation wicri:level="1"><nlm:affiliation>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Huffman, J" sort="Huffman, J" uniqKey="Huffman J" first="J" last="Huffman">J. Huffman</name>
<affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Kardia, S L R" sort="Kardia, S L R" uniqKey="Kardia S" first="S L R" last="Kardia">S L R. Kardia</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kochan, N" sort="Kochan, N" uniqKey="Kochan N" first="N" last="Kochan">N. Kochan</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Knopman, D S" sort="Knopman, D S" uniqKey="Knopman D" first="D S" last="Knopman">D S Knopman</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, Mayo Clinic, Rochester, MN, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Mayo Clinic, Rochester, MN</wicri:regionArea>
<placeName><region type="state">Minnesota</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kwok, J B" sort="Kwok, J B" uniqKey="Kwok J" first="J B" last="Kwok">J B Kwok</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Neuroscience Research Australia, Randwick, NSW, Australia [2] School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Neuroscience Research Australia, Randwick, NSW, Australia [2] School of Medical Sciences, University of New South Wales, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lambert, J C" sort="Lambert, J C" uniqKey="Lambert J" first="J-C" last="Lambert">J-C Lambert</name>
<affiliation wicri:level="3"><nlm:affiliation>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique, Lille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Inserm-UMR744, Institut Pasteur de Lille, Unité d'Epidémiologie et de Santé Publique, Lille</wicri:regionArea>
<placeName><region type="region">Hauts-de-France</region>
<region type="old region">Nord-Pas-de-Calais</region>
<settlement type="city">Lille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lee, T" sort="Lee, T" uniqKey="Lee T" first="T" last="Lee">T. Lee</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Li, G" sort="Li, G" uniqKey="Li G" first="G" last="Li">G. Li</name>
<affiliation wicri:level="4"><nlm:affiliation>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Li, S C" sort="Li, S C" uniqKey="Li S" first="S-C" last="Li">S-C Li</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Max Planck Institute for Human Development, Berlin, Germany [2] Technische Universität Dresden, Dresden, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>1] Max Planck Institute for Human Development, Berlin, Germany [2] Technische Universität Dresden, Dresden</wicri:regionArea>
<placeName><region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
<settlement type="city">Dresde</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Loitfelder, M" sort="Loitfelder, M" uniqKey="Loitfelder M" first="M" last="Loitfelder">M. Loitfelder</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Medical University of Graz, Graz, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Neurology, Medical University of Graz, Graz</wicri:regionArea>
<wicri:noRegion>Graz</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lopez, O L" sort="Lopez, O L" uniqKey="Lopez O" first="O L" last="Lopez">O L Lopez</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of Pittsburgh, Pittsburgh, PA</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">Pittsburgh</settlement>
</placeName>
<orgName type="university">Université de Pittsburgh</orgName>
</affiliation>
</author>
<author><name sortKey="Lundervold, A J" sort="Lundervold, A J" uniqKey="Lundervold A" first="A J" last="Lundervold">A J Lundervold</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway [2] Kavli Research Centre for Aging and Dementia, Haraldsplass Deaconess Hospital, Bergen, Norway [3] K.G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>1] Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway [2] Kavli Research Centre for Aging and Dementia, Haraldsplass Deaconess Hospital, Bergen, Norway [3] K.G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen, Bergen</wicri:regionArea>
<wicri:noRegion>Bergen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lundqvist, A" sort="Lundqvist, A" uniqKey="Lundqvist A" first="A" last="Lundqvist">A. Lundqvist</name>
<affiliation wicri:level="1"><nlm:affiliation>Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå</wicri:regionArea>
<wicri:noRegion>Umeå</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mather, K A" sort="Mather, K A" uniqKey="Mather K" first="K A" last="Mather">K A Mather</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mirza, S S" sort="Mirza, S S" uniqKey="Mirza S" first="S S" last="Mirza">S S Mirza</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nyberg, L" sort="Nyberg, L" uniqKey="Nyberg L" first="L" last="Nyberg">L. Nyberg</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden [2] Department of Radiation Sciences, Umeå University, Umeå, Sweden [3] Department of Integrative Medical Biology, Umeå University, Umeå, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>1] Umeå Center for Functional Brain Imaging (UFBI), Umeå University, Umeå, Sweden [2] Department of Radiation Sciences, Umeå University, Umeå, Sweden [3] Department of Integrative Medical Biology, Umeå University, Umeå</wicri:regionArea>
<wicri:noRegion>Umeå</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Oostra, B A" sort="Oostra, B A" uniqKey="Oostra B" first="B A" last="Oostra">B A Oostra</name>
<affiliation wicri:level="3"><nlm:affiliation>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Palotie, A" sort="Palotie, A" uniqKey="Palotie A" first="A" last="Palotie">A. Palotie</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK [2] Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland [3] Department of Medical Genetics, University of Helsinki and University Central Hospital, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>1] Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK [2] Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland [3] Department of Medical Genetics, University of Helsinki and University Central Hospital, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName><settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Papenberg, G" sort="Papenberg, G" uniqKey="Papenberg G" first="G" last="Papenberg">G. Papenberg</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Max Planck Institute for Human Development, Berlin, Germany [2] Karolinska Institutet, Aging Research Center, Stockholm University, Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>1] Max Planck Institute for Human Development, Berlin, Germany [2] Karolinska Institutet, Aging Research Center, Stockholm University, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
<settlement type="city">Stockholm</settlement>
</placeName>
<orgName type="university">Université de Stockholm</orgName>
</affiliation>
</author>
<author><name sortKey="Pattie, A" sort="Pattie, A" uniqKey="Pattie A" first="A" last="Pattie">A. Pattie</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Petrovic, K" sort="Petrovic, K" uniqKey="Petrovic K" first="K" last="Petrovic">K. Petrovic</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Medical University of Graz, Graz, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Neurology, Medical University of Graz, Graz</wicri:regionArea>
<wicri:noRegion>Graz</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Polasek, O" sort="Polasek, O" uniqKey="Polasek O" first="O" last="Polasek">O. Polasek</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Medicine, Department of Public Health, University of Split, Split, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Faculty of Medicine, Department of Public Health, University of Split, Split</wicri:regionArea>
<wicri:noRegion>Split</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Psaty, B M" sort="Psaty, B M" uniqKey="Psaty B" first="B M" last="Psaty">B M Psaty</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA [2] Deparment of Epidemiology, University of Washington, Seattle, WA, USA [3] Deparment of Health Services, University of Washington, Seattle, WA, USA [4] Group Health Research Unit, Group Health Cooperative, Seattle, WA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA [2] Deparment of Epidemiology, University of Washington, Seattle, WA, USA [3] Deparment of Health Services, University of Washington, Seattle, WA, USA [4] Group Health Research Unit, Group Health Cooperative, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Redmond, P" sort="Redmond, P" uniqKey="Redmond P" first="P" last="Redmond">P. Redmond</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Reppermund, S" sort="Reppermund, S" uniqKey="Reppermund S" first="S" last="Reppermund">S. Reppermund</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rotter, J I" sort="Rotter, J I" uniqKey="Rotter J" first="J I" last="Rotter">J I Rotter</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center, Los Angeles, CA, USA [2] Division of Genetic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center, Los Angeles, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center, Los Angeles, CA, USA [2] Division of Genetic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center, Los Angeles, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schmidt, H" sort="Schmidt, H" uniqKey="Schmidt H" first="H" last="Schmidt">H. Schmidt</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Department of Neurology, Medical University of Graz, Graz, Austria [2] Centre for Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>1] Department of Neurology, Medical University of Graz, Graz, Austria [2] Centre for Molecular Medicine, Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz</wicri:regionArea>
<wicri:noRegion>Graz</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schuur, M" sort="Schuur, M" uniqKey="Schuur M" first="M" last="Schuur">M. Schuur</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schofield, P W" sort="Schofield, P W" uniqKey="Schofield P" first="P W" last="Schofield">P W Schofield</name>
<affiliation wicri:level="1"><nlm:affiliation>School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Medicine and Public Health, University of Newcastle, Newcastle, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Scott, R J" sort="Scott, R J" uniqKey="Scott R" first="R J" last="Scott">R J Scott</name>
<affiliation wicri:level="1"><nlm:affiliation>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Steen, V M" sort="Steen, V M" uniqKey="Steen V" first="V M" last="Steen">V M Steen</name>
<affiliation wicri:level="1"><nlm:affiliation>1] K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen, Bergen, Norway [2] Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>1] K.G. Jebsen Centre for Psychosis Research and the Norwegian Centre for Mental Disorders Research (NORMENT), Department of Clinical Science, University of Bergen, Bergen, Norway [2] Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen</wicri:regionArea>
<wicri:noRegion>Bergen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stott, D J" sort="Stott, D J" uniqKey="Stott D" first="D J" last="Stott">D J Stott</name>
<affiliation wicri:level="4"><nlm:affiliation>Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow</wicri:regionArea>
<orgName type="university">Université de Glasgow</orgName>
<placeName><settlement type="city">Glasgow</settlement>
<region type="country">Écosse</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Van Swieten, J C" sort="Van Swieten, J C" uniqKey="Van Swieten J" first="J C" last="Van Swieten">J C Van Swieten</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Erasmus University Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Taylor, K D" sort="Taylor, K D" uniqKey="Taylor K" first="K D" last="Taylor">K D Taylor</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center, Los Angeles, CA, USA [2] Department of Pediatrics, Harbor-UCLA Medical Center, Los Angeles, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Institute for Translational Genomics and Population Sciences Los Angeles BioMedical Research Institute, Harbor-UCLA Medical Center, Los Angeles, CA, USA [2] Department of Pediatrics, Harbor-UCLA Medical Center, Los Angeles, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Trollor, J" sort="Trollor, J" uniqKey="Trollor J" first="J" last="Trollor">J. Trollor</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Trompet, S" sort="Trompet, S" uniqKey="Trompet S" first="S" last="Trompet">S. Trompet</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands [2] Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands [2] Department of Cardiology, Leiden University Medical Center, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Uitterlinden, A G" sort="Uitterlinden, A G" uniqKey="Uitterlinden A" first="A G" last="Uitterlinden">A G Uitterlinden</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands [3] Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands [3] Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Weinstein, G" sort="Weinstein, G" uniqKey="Weinstein G" first="G" last="Weinstein">G. Weinstein</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Widen, E" sort="Widen, E" uniqKey="Widen E" first="E" last="Widen">E. Widen</name>
<affiliation wicri:level="4"><nlm:affiliation>Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName><settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Windham, B G" sort="Windham, B G" uniqKey="Windham B" first="B G" last="Windham">B G Windham</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Geriatrics, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Geriatrics, Department of Medicine, University of Mississippi Medical Center, Jackson, MS</wicri:regionArea>
<placeName><region type="state">État du Mississippi</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jukema, J W" sort="Jukema, J W" uniqKey="Jukema J" first="J W" last="Jukema">J W Jukema</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands [2] Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands [3] Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands [2] Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands [3] Interuniversity Cardiology Institute of the Netherlands, Utrecht</wicri:regionArea>
<placeName><settlement type="city">Utrecht</settlement>
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<author><name sortKey="Wright, A F" sort="Wright, A F" uniqKey="Wright A" first="A F" last="Wright">A F Wright</name>
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<country xml:lang="fr">Royaume-Uni</country>
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<placeName><settlement type="city">Édimbourg</settlement>
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<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
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<author><name sortKey="Wright, M J" sort="Wright, M J" uniqKey="Wright M" first="M J" last="Wright">M J Wright</name>
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<country xml:lang="fr">Australie</country>
<wicri:regionArea>Neuroimaging Genetics Group, QIMR Berghofer Medical Research Institute, Brisbane, QLD</wicri:regionArea>
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</author>
<author><name sortKey="Yang, Q" sort="Yang, Q" uniqKey="Yang Q" first="Q" last="Yang">Q. Yang</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Framingham Heart Study, Framingham, MA, USA [2] Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Framingham Heart Study, Framingham, MA, USA [2] Department of Biostatistics, Boston University School of Public Health, Boston, MA</wicri:regionArea>
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</placeName>
</affiliation>
</author>
<author><name sortKey="Amieva, H" sort="Amieva, H" uniqKey="Amieva H" first="H" last="Amieva">H. Amieva</name>
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<country xml:lang="fr">France</country>
<wicri:regionArea>Inserm U897, Université Bordeaux Segalen, Bordeaux</wicri:regionArea>
<placeName><region type="region">Nouvelle-Aquitaine</region>
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<settlement type="city">Bordeaux</settlement>
<settlement type="city">Bordeaux</settlement>
</placeName>
<orgName type="university">Université Bordeaux II</orgName>
</affiliation>
</author>
<author><name sortKey="Attia, J R" sort="Attia, J R" uniqKey="Attia J" first="J R" last="Attia">J R Attia</name>
<affiliation wicri:level="1"><nlm:affiliation>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Hunter Medical Research Institute and Faculty of Health, University of Newcastle, Newcastle, NSW</wicri:regionArea>
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</author>
<author><name sortKey="Bennett, D A" sort="Bennett, D A" uniqKey="Bennett D" first="D A" last="Bennett">D A Bennett</name>
<affiliation wicri:level="2"><nlm:affiliation>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Brodaty, H" sort="Brodaty, H" uniqKey="Brodaty H" first="H" last="Brodaty">H. Brodaty</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Dementia Collaborative Research Centre, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Dementia Collaborative Research Centre, University of New South Wales, Sydney, NSW</wicri:regionArea>
<wicri:noRegion>NSW</wicri:noRegion>
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</author>
<author><name sortKey="De Craen, A J M" sort="De Craen, A J M" uniqKey="De Craen A" first="A J M" last="De Craen">A J M. De Craen</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hayward, C" sort="Hayward, C" uniqKey="Hayward C" first="C" last="Hayward">C. Hayward</name>
<affiliation wicri:level="4"><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Ikram, M A" sort="Ikram, M A" uniqKey="Ikram M" first="M A" last="Ikram">M A Ikram</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [3] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands [4] Department of Radiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [3] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands [4] Department of Radiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
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<author><name sortKey="Lindenberger, U" sort="Lindenberger, U" uniqKey="Lindenberger U" first="U" last="Lindenberger">U. Lindenberger</name>
<affiliation wicri:level="3"><nlm:affiliation>Max Planck Institute for Human Development, Berlin, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Max Planck Institute for Human Development, Berlin</wicri:regionArea>
<placeName><region type="land" nuts="3">Berlin</region>
<settlement type="city">Berlin</settlement>
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</affiliation>
</author>
<author><name sortKey="Nilsson, L G" sort="Nilsson, L G" uniqKey="Nilsson L" first="L-G" last="Nilsson">L-G Nilsson</name>
<affiliation wicri:level="1"><nlm:affiliation>ARC, Karolinska Institutet, Stockholm and UFBI, Umeå University, Umeå, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>ARC, Karolinska Institutet, Stockholm and UFBI, Umeå University, Umeå</wicri:regionArea>
<wicri:noRegion>Umeå</wicri:noRegion>
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</author>
<author><name sortKey="Porteous, D J" sort="Porteous, D J" uniqKey="Porteous D" first="D J" last="Porteous">D J Porteous</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK [3] Generation Scotland, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK [3] Generation Scotland, University of Edinburgh Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
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<orgName type="university">Université d'Édimbourg</orgName>
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</author>
<author><name sortKey="R Ikkonen, K" sort="R Ikkonen, K" uniqKey="R Ikkonen K" first="K" last="R Ikkönen">K. R Ikkönen</name>
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<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Behavioural Sciences, University of Helsinki, Helsinki</wicri:regionArea>
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</affiliation>
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<author><name sortKey="Reinvang, I" sort="Reinvang, I" uniqKey="Reinvang I" first="I" last="Reinvang">I. Reinvang</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Psychology, University of Oslo, Oslo, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Department of Psychology, University of Oslo, Oslo</wicri:regionArea>
<placeName><settlement type="city">Oslo</settlement>
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</affiliation>
</author>
<author><name sortKey="Rudan, I" sort="Rudan, I" uniqKey="Rudan I" first="I" last="Rudan">I. Rudan</name>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
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<author><name sortKey="Sachdev, P S" sort="Sachdev, P S" uniqKey="Sachdev P" first="P S" last="Sachdev">P S Sachdev</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, Australia [2] Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW</wicri:regionArea>
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<author><name sortKey="Schmidt, R" sort="Schmidt, R" uniqKey="Schmidt R" first="R" last="Schmidt">R. Schmidt</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Medical University of Graz, Graz, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Neurology, Medical University of Graz, Graz</wicri:regionArea>
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</author>
<author><name sortKey="Schofield, P R" sort="Schofield, P R" uniqKey="Schofield P" first="P R" last="Schofield">P R Schofield</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Neuroscience Research Australia, Sydney, NSW, Australia [2] Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Neuroscience Research Australia, Sydney, NSW, Australia [2] Faculty of Medicine, University of New South Wales, Sydney, NSW</wicri:regionArea>
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<author><name sortKey="Srikanth, V" sort="Srikanth, V" uniqKey="Srikanth V" first="V" last="Srikanth">V. Srikanth</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Menzies Research Institute, Hobart, Tasmania [2] Stroke and Ageing Research, Medicine, Southern Clinical School, Monash University, Melbourne, VIC, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>1] Menzies Research Institute, Hobart, Tasmania [2] Stroke and Ageing Research, Medicine, Southern Clinical School, Monash University, Melbourne, VIC</wicri:regionArea>
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<author><name sortKey="Starr, J M" sort="Starr, J M" uniqKey="Starr J" first="J M" last="Starr">J M Starr</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Turner, S T" sort="Turner, S T" uniqKey="Turner S" first="S T" last="Turner">S T Turner</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN</wicri:regionArea>
<placeName><region type="state">Minnesota</region>
</placeName>
</affiliation>
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<author><name sortKey="Weir, D R" sort="Weir, D R" uniqKey="Weir D" first="D R" last="Weir">D R Weir</name>
<affiliation wicri:level="2"><nlm:affiliation>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
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<author><name sortKey="Wilson, J F" sort="Wilson, J F" uniqKey="Wilson J" first="J F" last="Wilson">J F Wilson</name>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
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<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Van Duijn, C" sort="Van Duijn, C" uniqKey="Van Duijn C" first="C" last="Van Duijn">C. Van Duijn</name>
<affiliation wicri:level="3"><nlm:affiliation>1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Ageing, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
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</affiliation>
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<author><name sortKey="Launer, L" sort="Launer, L" uniqKey="Launer L" first="L" last="Launer">L. Launer</name>
<affiliation wicri:level="2"><nlm:affiliation>Intramural Research Program National Institutes on Aging, National Institutes of Health, Bethesda, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Intramural Research Program National Institutes on Aging, National Institutes of Health, Bethesda, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fitzpatrick, A L" sort="Fitzpatrick, A L" uniqKey="Fitzpatrick A" first="A L" last="Fitzpatrick">A L Fitzpatrick</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Deparment of Epidemiology, University of Washington, Seattle, WA, USA [2] Department of Global Health, University of Washington, Seattle, WA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Deparment of Epidemiology, University of Washington, Seattle, WA, USA [2] Department of Global Health, University of Washington, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
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<orgName type="university">Université de Washington</orgName>
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</author>
<author><name sortKey="Seshadri, S" sort="Seshadri, S" uniqKey="Seshadri S" first="S" last="Seshadri">S. Seshadri</name>
<affiliation wicri:level="2"><nlm:affiliation>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>1] Department of Neurology, Boston University School of Medicine, Boston, MA, USA [2] Framingham Heart Study, Framingham, MA</wicri:regionArea>
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</affiliation>
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<author><name sortKey="Mosley, T H" sort="Mosley, T H" uniqKey="Mosley T" first="T H" last="Mosley">T H Mosley</name>
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<country xml:lang="fr">États-Unis</country>
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<author><name sortKey="Deary, I J" sort="Deary, I J" uniqKey="Deary I" first="I J" last="Deary">I J Deary</name>
<affiliation wicri:level="4"><nlm:affiliation>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK [2] Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
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<settlement type="city">Édimbourg</settlement>
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<series><title level="j">Molecular psychiatry</title>
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<front><div type="abstract" xml:lang="en">General cognitive function is substantially heritable across the human life course from adolescence to old age. We investigated the genetic contribution to variation in this important, health- and well-being-related trait in middle-aged and older adults. We conducted a meta-analysis of genome-wide association studies of 31 cohorts (N=53,949) in which the participants had undertaken multiple, diverse cognitive tests. A general cognitive function phenotype was tested for, and created in each cohort by principal component analysis. We report 13 genome-wide significant single-nucleotide polymorphism (SNP) associations in three genomic regions, 6q16.1, 14q12 and 19q13.32 (best SNP and closest gene, respectively: rs10457441, P=3.93 × 10(-9), MIR2113; rs17522122, P=2.55 × 10(-8), AKAP6; rs10119, P=5.67 × 10(-9), APOE/TOMM40). We report one gene-based significant association with the HMGN1 gene located on chromosome 21 (P=1 × 10(-6)). These genes have previously been associated with neuropsychiatric phenotypes. Meta-analysis results are consistent with a polygenic model of inheritance. To estimate SNP-based heritability, the genome-wide complex trait analysis procedure was applied to two large cohorts, the Atherosclerosis Risk in Communities Study (N=6617) and the Health and Retirement Study (N=5976). The proportion of phenotypic variation accounted for by all genotyped common SNPs was 29% (s.e.=5%) and 28% (s.e.=7%), respectively. Using polygenic prediction analysis, ~1.2% of the variance in general cognitive function was predicted in the Generation Scotland cohort (N=5487; P=1.5 × 10(-17)). In hypothesis-driven tests, there was significant association between general cognitive function and four genes previously associated with Alzheimer's disease: TOMM40, APOE, ABCG1 and MEF2C.</div>
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