Late-born intermittently fasted juvenile garden dormice use torpor to grow and fatten prior to hibernation: consequences for ageing processes.
Identifieur interne : 001F65 ( Ncbi/Checkpoint ); précédent : 001F64; suivant : 001F66Late-born intermittently fasted juvenile garden dormice use torpor to grow and fatten prior to hibernation: consequences for ageing processes.
Auteurs : Sylvain Giroud [Autriche] ; Sandrine Zahn [France] ; François Criscuolo [France] ; Isabelle Chery [France] ; Stéphane Blanc [France] ; Christopher Turbill [Australie] ; Thomas Ruf [Autriche]Source :
- Proceedings. Biological sciences [ 1471-2954 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- croissance et développement : Myoxidae.
- génétique : Vieillissement.
- physiologie : Myoxidae.
- Animaux, Composition corporelle, Consommation alimentaire, Données de séquences moléculaires, Facteurs temps, Femelle, Hibernation, Homéostasie des télomères, Mâle, Privation alimentaire, Saisons, Torpeur.
English descriptors
- KwdEn :
- MESH :
- genetics : Aging.
- growth & development : Myoxidae.
- physiology : Myoxidae.
- Animals, Body Composition, Eating, Female, Food Deprivation, Hibernation, Male, Molecular Sequence Data, Seasons, Telomere Homeostasis, Time Factors, Torpor.
Abstract
Torpor is thought to slow age-related processes and to sustain growth and fattening of young individuals. Energy allocation into these processes represents a challenge for juveniles, especially for those born late in the season. We tested the hypothesis that late-born juvenile garden dormice (Eliomys quercinus) fed ad libitum ('AL', n = 9) or intermittently fasted ('IF', n = 9) use short torpor bouts to enhance growth and fat accumulation to survive winter. IF juveniles displayed more frequent and longer torpor bouts, compared with AL individuals before hibernation. Torpor frequency correlated negatively with energy expenditure and water turnover. Hence, IF juveniles gained mass at the same rate, reached similar pre-hibernation fattening and displayed identical hibernating patterns and mass losses as AL animals. We found no group differences in relative telomere length (RTL), an indicator of ageing, during the period of highest summer mass gain, despite greater torpor use by IF juveniles. Percentage change in RTL was negatively associated with mean and total euthermic durations among all individuals during hibernation. We conclude that torpor use promotes fattening in late-born juvenile dormice prior to hibernation. Furthermore, we provided the first evidence for a functional link between time spent in euthermy and ageing processes over winter.
DOI: 10.1098/rspb.2014.1131
PubMed: 25377448
Affiliations:
- Australie, Autriche, France
- Alsace (région administrative), Grand Est, Vienne (Autriche)
- Strasbourg, Vienne (Autriche)
- Université de Strasbourg
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Biological sciences</title><idno type="eISSN">1471-2954</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aging (genetics)</term><term>Animals</term><term>Body Composition</term><term>Eating</term><term>Female</term><term>Food Deprivation</term><term>Hibernation</term><term>Male</term><term>Molecular Sequence Data</term><term>Myoxidae (growth & development)</term><term>Myoxidae (physiology)</term><term>Seasons</term><term>Telomere Homeostasis</term><term>Time Factors</term><term>Torpor</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Composition corporelle</term><term>Consommation alimentaire</term><term>Données de séquences moléculaires</term><term>Facteurs temps</term><term>Femelle</term><term>Hibernation</term><term>Homéostasie des télomères</term><term>Myoxidae (croissance et développement)</term><term>Myoxidae (physiologie)</term><term>Mâle</term><term>Privation alimentaire</term><term>Saisons</term><term>Torpeur</term><term>Vieillissement (génétique)</term></keywords><keywords scheme="MESH" qualifier="croissance et développement" xml:lang="fr"><term>Myoxidae</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Aging</term></keywords><keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Myoxidae</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Vieillissement</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Myoxidae</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Myoxidae</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Body Composition</term><term>Eating</term><term>Female</term><term>Food Deprivation</term><term>Hibernation</term><term>Male</term><term>Molecular Sequence Data</term><term>Seasons</term><term>Telomere Homeostasis</term><term>Time Factors</term><term>Torpor</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Composition corporelle</term><term>Consommation alimentaire</term><term>Données de séquences moléculaires</term><term>Facteurs temps</term><term>Femelle</term><term>Hibernation</term><term>Homéostasie des télomères</term><term>Mâle</term><term>Privation alimentaire</term><term>Saisons</term><term>Torpeur</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Torpor is thought to slow age-related processes and to sustain growth and fattening of young individuals. Energy allocation into these processes represents a challenge for juveniles, especially for those born late in the season. We tested the hypothesis that late-born juvenile garden dormice (Eliomys quercinus) fed ad libitum ('AL', n = 9) or intermittently fasted ('IF', n = 9) use short torpor bouts to enhance growth and fat accumulation to survive winter. IF juveniles displayed more frequent and longer torpor bouts, compared with AL individuals before hibernation. Torpor frequency correlated negatively with energy expenditure and water turnover. Hence, IF juveniles gained mass at the same rate, reached similar pre-hibernation fattening and displayed identical hibernating patterns and mass losses as AL animals. We found no group differences in relative telomere length (RTL), an indicator of ageing, during the period of highest summer mass gain, despite greater torpor use by IF juveniles. Percentage change in RTL was negatively associated with mean and total euthermic durations among all individuals during hibernation. We conclude that torpor use promotes fattening in late-born juvenile dormice prior to hibernation. Furthermore, we provided the first evidence for a functional link between time spent in euthermy and ageing processes over winter.</div></front></TEI><affiliations><list><country><li>Australie</li><li>Autriche</li><li>France</li></country><region><li>Alsace (région administrative)</li><li>Grand Est</li><li>Vienne (Autriche)</li></region><settlement><li>Strasbourg</li><li>Vienne (Autriche)</li></settlement><orgName><li>Université de Strasbourg</li></orgName></list><tree><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Giroud, Sylvain" sort="Giroud, Sylvain" uniqKey="Giroud S" first="Sylvain" last="Giroud">Sylvain Giroud</name></region><name sortKey="Ruf, Thomas" sort="Ruf, Thomas" uniqKey="Ruf T" first="Thomas" last="Ruf">Thomas Ruf</name></country><country name="France"><region name="Grand Est"><name sortKey="Zahn, Sandrine" sort="Zahn, Sandrine" uniqKey="Zahn S" first="Sandrine" last="Zahn">Sandrine Zahn</name></region><name sortKey="Blanc, Stephane" sort="Blanc, Stephane" uniqKey="Blanc S" first="Stéphane" last="Blanc">Stéphane Blanc</name><name sortKey="Chery, Isabelle" sort="Chery, Isabelle" uniqKey="Chery I" first="Isabelle" last="Chery">Isabelle Chery</name><name sortKey="Criscuolo, Francois" sort="Criscuolo, Francois" uniqKey="Criscuolo F" first="François" last="Criscuolo">François Criscuolo</name></country><country name="Australie"><noRegion><name sortKey="Turbill, Christopher" sort="Turbill, Christopher" uniqKey="Turbill C" first="Christopher" last="Turbill">Christopher Turbill</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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