AustralieFrV1, Main, Exploration, bibRecord, 001276

A perspective on the contribution of animal models to the pharmacological treatment of posttraumatic stress disorder.

Identifieur interne : 001276 ( Main/Exploration ); précédent : 001275; suivant : 001277

A perspective on the contribution of animal models to the pharmacological treatment of posttraumatic stress disorder.

Auteurs : Valerie Bertaina-Anglade [France] ; Susan M. O'Connor [Australie] ; Emile Andriambeloson [France]

Source :

Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists [ 1440-1665 ] ; 2017.

RBID : pubmed:28747120

Abstract

Posttraumatic stress disorder (PTSD) is a prevalent, chronic, disabling disorder that may develop following exposure to a traumatic event. This review summarizes currently used animal models of PTSD and their potential role in the development of better therapeutics. Heterogeneity is one of the main characteristics of PTSD with the consequence that many pharmacological approaches are used to relieve symptoms of PTSD. To address the translational properties of the animal models, we discuss the types of stressors used, the rodent correlates of human PTSD (DSM-5) symptoms, and the efficacy of approved, recommended and off-label drugs used to treat PTSD in 'PTSD-animals'.

DOI: 10.1177/1039856217716288
PubMed: 28747120

Affiliations:

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<front><div type="abstract" xml:lang="en">Posttraumatic stress disorder (PTSD) is a prevalent, chronic, disabling disorder that may develop following exposure to a traumatic event. This review summarizes currently used animal models of PTSD and their potential role in the development of better therapeutics. Heterogeneity is one of the main characteristics of PTSD with the consequence that many pharmacological approaches are used to relieve symptoms of PTSD. To address the translational properties of the animal models, we discuss the types of stressors used, the rodent correlates of human PTSD (DSM-5) symptoms, and the efficacy of approved, recommended and off-label drugs used to treat PTSD in 'PTSD-animals'.</div>
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A perspective on the contribution of animal models to the pharmacological treatment of posttraumatic stress disorder.

A perspective on the contribution of animal models to the pharmacological treatment of posttraumatic stress disorder.

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur les relations entre la France et l'Australie
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